剖宫产术后瘢痕子宫再妊娠分娩方式的临床分析

目的探讨剖宫产术后产妇再妊娠分娩方式的选择及对母婴的影响。方法对210例剖宫产术后再妊娠产妇分娩方式及母婴并发症的发生进行回顾性分析,并随机抽取同期186例行首次剖宫产产妇和24例非瘢痕子宫分娩初产妇进行对比分析。结果210例剖宫产术后再妊娠产妇37例阴道试产,24例试产成功;剖宫产术后阴道分娩组产后出血量、住院时间、住院费用及腹腔粘连发生率与剖宫产术后阴道分娩组比较差异均有统计学意义（P〈0．05）,新生儿窒息及产褥感染发生率差异无统计学意义;再次剖宫产组腹腔粘连、切口乙级愈合及产后出血率与首次剖宫产组比较差异有统计学意义（P〈0．05）。结论瘢痕子宫并不是剖宫产手术的指征,再次行剖宫产致产妇并发症增加,适合试产条件的产妇应提倡阴道试产。     

剖宫产术后再次妊娠分娩方式的探讨

目的探讨剖宫产手术后再次妊娠分娩方式的选择。方法对剖宫产手术后再次妊娠210例孕妇的分娩方式、分娩结局、母婴并发症及医疗费用进行回顾性分析。结果210例中阴道试产40例,成功27例,成功率67．5％;再次剖宫产183例,手术产率87．14％。剖宫产术后阴道分娩组新生儿窒息、产后出血量、先兆子宫破裂发生率与非瘢痕子宫阴道分娩组比较差异无显著性（P＞0．05）。再次剖宫产组产后出血、腹腔粘连、切1：3乙级愈合发生率与首次剖宫产组比较差异有显著性（P〈0．05）。再次剖宫产组与剖宫产术后阴道分娩组比较产后出血量、住院费用差异均有显著性（P＜0．01）,住院天数差异有显著性（P＜0.05）。结论剖宫产术后再次妊娠,只要条件符合,应给予充分阴道试产的机会。     

疤痕子宫再次妊娠分娩方式的探讨

目的 探讨疤痕子宫再次妊娠的分娩方式。方法 对2000年5月-2006年5月我院128例剖宫产术后再次妊娠孕妇的分娩方式、分娩结局及母婴并发症进行回顾性分析，并将其中再次剖宫产（RCS）83例与随机抽取同期首次剖宫产（PCS）83例进行对照；将其中剖宫产术后阴道分娩（VBAC）45例与随机抽取同期非疤痕子宫阴道分娩（VBNC）45例进行对照。结果 128例中62例行阴道试产，45例试产成功，成功率72．58％；RCS83例，手术产率64．84％。VBAC组新生儿窒息、产后出血量、先兆子宫破裂发生率与VBNC组比较差异无显著性意义（P〉0．05）。RCS组产后出血量、平均住院天数与VBAC组比较差异有显著性意义（P〈0．05）；RCS组产后出血量、重度粘连，切口乙级愈合发生率与PCS组比较差异有显著性意义（P〈0．05）。结论 疤痕子宫再次妊娠分娩并非剖宫产绝对指征，符合试产条件者应给予充分的阴道试产机会。     

剖宫产术后再次妊娠158例临床分析

目的：探讨剖宫产术后再次妊娠的分娩方式。方法：对1996年1月-2006年12月我院158例剖宫产术后再次妊娠孕妇的分娩方式、分娩结局及母婴并发症进行回顾性分析，将再次剖宫产115例患者与随机抽样的同期首次剖宫产115例进行对照；将剖宫产术后再次妊娠阴道分娩的43例与随机抽取的同期非瘢痕子宫阴道分娩者43例进行对照。结果：158例中，66例进行阴道试产，43例成功阴道分娩，成功率65．2％；再次剖宫产115例，手术产率72．8％。剖宫产术后再次妊娠阴道分娩组无新生儿窒息，产后出血及子宫破裂发生率与对照组比较差异无统计学意义。再次剖宫产组产后出血量比剖宫产术后再次妊娠阴道分娩组高，平均住院天数长，产后出血、严重粘连、切口愈合不良发生率均较首次剖宫产组高，差异有统计学意义（P〈0．05）。结论：剖宫产术后再次妊娠分娩并非是剖宫产绝对指征，凡具备试产条件者在严密监护下阴道试产是安全的。     

剖宫产术后再次妊娠经阴道分娩可行性分析

目的：探讨剖宫产术后再次妊娠经阴道分娩的可行性。方法：回顾性分析本院收治的323例具有剖宫产史再次妊娠产妇的临床资料。将剖宫产术后选择经阴道试产组83例与选择再次剖宫产组240例的产后平均出血量、产后出血、新生儿窒息、产褥病、平均住院天数进行比较,并随机抽取同期非疤痕子宫选择经阴道试产组83例进行对照。结果：323例中83例选择阴道试产,占25．70％（83/323）,其中73例试产成功,成功率87．95％（73/83）,试产失败10例,占12．05％（10/83）,再次选择剖宫产240例,占74．30％（240/323）。剖宫产术后选择经阴道试产组与RCS组比较产后出血率、新生儿窒息率差异无统计学意义（P＞0．05）,产后平均出血量差异有统计学意义（P＜0．05）,平均住院天数差异有显著性意义（P＜0．01）。与对照组比较差异均无统计学意义（P＞0．05）。三组产妇均未并发产褥病。结论：严格把握剖宫产术后再次妊娠经阴道试产的适应证,严密监护下阴道试产是安全可行的,可比再次剖宫产组明显缩短平均住院天数。     

剖宫产术后再次妊娠分娩300例临床分析

目的探讨剖宫产术后再次妊娠的分娩方式。方法对300例剖宫产术后再次妊娠孕妇的分娩方式、分娩结局及母婴并发症进行回顾分析，并与随机抽取同期首次剖宫产216例进行对照，将其中剖宫产术后阴道分娩80例与随机抽取同期非瘢痕子宫阴道分娩80例进行对照。结果300例中108例阴道试产，80例试产成功，成功率为74.07％。剖宫产术后阴道分娩组无新生几窒息、产后出血量、先兆子宫破裂发生率与对照组比较差异无统计学意义。再次剖宫产术后出血量比剖宫产术后阴道分娩组高，平均住院天数比剖宫产术后经阴道分娩组长，产后出血、严重粘连发生率均较首次剖宫产组高，差异有统计学意义（P〈0．05）：结论剖宫产术后再次妊娠分娩并非是剖宫产绝对指征，符合试产条件者，严密监护下阴道试产是安全的。     

剖宫产术后再次妊娠分娩方式的临床分析

目的：研讨剖宫产术后再次妊娠妇女再次剖宫产和经阴道分娩方式的选择及其临床意义。方法：收集我院生产的产妇资料,筛选其中经剖宫产术再次妊娠的产妇共465例,按其选择的分娩方式将其分为剖宫产组（ n＝340）和阴道分娩组（ n＝125）,比较两种分娩方式下产妇及新生儿的临床结局。结果：剖宫产组产妇产后出血量（289．51±4．37）mL、住院时间（6．95±1．02）d,产后感染发生率12．65％,显著高于阴道试产组的相关指标,差异均有统计学意义（P ＜0．05）。剖宫产组新生儿体重（3495±511）g,5 min Apgar评分＜710例,新生儿感染率4．71％,与阴道分娩组相关指标无显著性差异（P＞0．05）。结论：剖宫产术后再次妊娠产妇在选择分娩方式的时候,在条件允许、严密监控的情况下经阴道试产安全、有效、经济,且能在一定程度上改善产妇的临床结局。     

瘢痕子宫再次妊娠分娩方式剖析

目的：对瘢痕子宫再次妊娠分娩方式进行分析。方法：选取2009年12月～2013年12月瘢痕子宫再次妊娠患者306例,随机分为2组,试产组152例,进行阴道试产;手术组154例,均进行再次剖宫产手术;对比患者的分娩成功率。结果：试产组成功阴道分娩80例,试产成功率52．63％,其中72例中转剖宫产手术;2组患者新生儿Apgar评分差异无统计学意义（P〉0．05）,但试产组剖宫产手术手术时间、术中出血量、产后出血比例明显高于剖产组,差异有统计学意义（P〈0．05）。无新生儿和产妇死亡病例。结论：针对瘢痕子宫患者再次妊娠分娩,应依据患者的情况进行再次分娩的方法选择,但应选择对产妇和胎儿安全的分娩方式,产妇身体条件较好,在严格观察的情况下,可进行阴道试产。     

剖宫产术后再次妊娠分娩方式168例临床分析

目的探讨剖宫产术后再次妊娠分娩方式的选择。方法对本院剖宫产后再次妊娠的168例孕妇分娩方式进行回顾性分析。结果阴道试产38例（试产率21．43％）,阴道分娩33例,试产成功率91．67％;再次剖宫产135例（占80．36％）,其中有剖宫产指征者64例（47．41％）,无指征者71例（52．59％）。再次剖宫产（RCS）组的出血量、平均住院日等与阴道分娩（VBAC）组相比,差异有统计学意义（P〈0．05）。结论单纯剖宫产史作为再次剖宫产的指征是不合理的,阴道分娩可减少再次手术给患者带来的各种痛苦、并发症和经济负担。如无产科指征,应给予阴道试产的机会。     

52例剖宫产后再次妊娠阴道分娩的可行性分析

目的探讨剖宫产术后再次妊娠阴道分娩对母婴结局的影响。方法选取52例剖宫产术后再次妊娠经阴道分娩的患者为观察对象,随机选取同期58例经阴道分娩的初产妇为对照组,对比分析两组产妇阴道试产成功率、不同产程时间、新生儿阿氏评分、产妇出血量以及住院时间。结果观察组阴道分娩试产成功率为57．69％,对照组为87．93％,两组比较差异无统计学意义（P〉0．05）。两组产妇产程所需时间、出血量、新生儿阿氏评分以及住院时间比较差异无统计学意义（P〉0．05）。结论瘢痕子宫不能作为剖宫产术的手术指征,对于符合阴道分娩的产妇应给予阴道试产的计划,提高瘢痕子宫患者自然分娩率。     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…