足三里穴药物注射治疗围化疗期恶心、呕吐的疗效观察及护理

目的:化疗是肿瘤患者常用的治疗方法,治疗中产生的恶心、呕吐不良反应常引起脱水、代谢紊乱等不良后果,严重者可影响化疗的正常进行。因此,为减轻患者化疗所致的胃肠道反应,采用胃复安加VitB6足三里穴位注射。方法:按随机对照原则,建立相应的治疗组和对照组,治疗组采用胃复安加VitB6足三里穴位注射,对照组采用胃复安肌内注射。结果:治疗组发生恶心反应42例,占87.5%,呕吐反应23例,占47.9%,6例无明显恶心呕吐;对照组发生恶心反应47例,占100%,呕吐反应38例,占80.8%,两组比较差异有统计学意义(P<0.05)。结论:足三里穴位药物注射治疗围化疗期恶心、呕吐的疗效显著。     

足三里穴位注射预防癌症患者化疗消化道反应的临床研究

目的 观察维生素B6足三里穴位注射对癌症患者化疗消化道反应的预防作用;方法将147例确诊为恶性肿瘤患者随机单盲法均分为三组:组1(维生素B6静脉滴注组)、组2(静脉推注恩丹西酮组)和组3(维生素B6穴位注射组),组1采用静脉滴注维生素B6200毫克,组2采用静脉推注恩丹西酮8毫克,组3采用足三里穴位注射维生素B6每穴各100毫克;均在化疗前30分钟开始治疗,然后观察化疗后第一、二、三天患者出现恶心呕吐、便秘、腹胀、腹痛的总的情况,并进行统计学分析比较;结果组3预防化疗后消化道反应完全有效、总有效率均极显著优于组1、组2(P<0.01);便秘、腹胀等副作用均极显著少于组1、组2 (P<0.01)并具有显著的效价比;结论维生素B6足三里穴位注射具有极显著的预防癌症化疗患者胃肠道毒性反应的作用,价效比显著,无明显不良反应,易推广.     

穴位注射防治全麻术后恶心呕吐的临床疗效观察

目的:观察穴位注射足三里防治全麻术后恶心呕吐的疗效。方法:对300例全麻手术患者进行术后临床观察,对照组150例,术前半小时给予胃复安、维生素B6静脉注射。治疗组150例,采用穴位注射足三里。结果:治疗组术后恶心、呕吐总发生率为9%,对照组术后恶心、呕吐总发生率为30%,两组发生率经统计学处理P<0.01,有明显差异。结论:穴位注射明显降低术后恶心、呕吐的发生率。     

穴位注射加耳穴压豆防治恶性肿瘤患者化疗致呕吐的临床观察

目的观察耳穴压豆加穴位注射方法预防和治疗恶性肿瘤病人在进行化疗时导致恶心呕吐的临床疗效。方法采取自身对照的方法对病人进行疗效观察。将21例病人首次化疗疗程采用传统静脉注射方法预防和治疗化疗药物导致的恶心呕吐。第2次化疗疗程则采用耳穴压豆加穴位注射来预防和治疗化疗药物导致的恶心呕吐。观察患者在化疗期间有无恶心呕吐等主观感受。结果其穴位注射加耳穴压豆法总有效率达85.6%,而传统治疗法为62%,差异有统计学意义(P<0.05)。结论穴位注射加耳穴压豆防治恶性肿瘤病人化疗导致呕吐的疗效明显。     

穴位贴敷疗法防治乳腺癌患者化疗所致恶心呕吐的临床观察

目的:观察穴位贴敷疗法防治乳腺癌患者化疗所致恶心呕吐的疗效。方法:选取乳腺癌患者200例作为研究对象,按照随机数字法分为对照组和观察组,每组各100例。对照组患者接受常规治疗干预,观察组患者在对照组基础上,穴位贴敷疗法;比较两组患者的对化疗所致恶心呕吐的临床疗效。结果:观察组患者的临床治疗效果显著优于对照组(P<0.01)。结论:在常规治疗基础上采用穴位贴敷疗法对缓解乳腺癌患者化疗所致恶心呕吐效果明显。     

温阳健脾理气汤联合穴位注射防治乳腺癌化疗后胃肠道不良反应临床研究

目的:研究温阳健脾理气汤联合穴位注射防治乳腺癌化疗后胃肠道不良反应的临床疗效。方法:选择108患者作为研究对象,随机分为3组,每组各36例,均予以盐酸多柔比星+环磷酰胺方案化疗,化疗同时空白组静脉滴注生理盐水,对照组采用静脉滴注盐酸阿扎司琼氯化钠注射液预防治疗,治疗组采用口服自拟温阳健脾理气汤加减联用足三里穴位注射维生素B6预防治疗。观察3组患者胃肠道反应的发生情况。结果:与空白组比较,对照组与治疗组中、重度胃肠道不良反应均较低,且治疗组低于对照组,差异有统计学意义(P0.01);未出现及出现轻度胃肠道反应方面,治疗组优于对照组,差异有统计学意义(P0.01)。结论:温阳健脾理气汤联用足三里穴位注射维生素B6在预防乳腺癌化疗后胃肠道反应中收效良好。     

针灸防治肿瘤患者化疗后恶心呕吐临床研究进展

探索针灸治疗肿瘤化疗后恶心呕吐最新临床研究进展,检索中国知网、万方、pubmed等中英文数据库,总结分析针灸治疗肿瘤患者化疗后恶心呕吐常用干预措施及其疗效,发现针灸治疗化疗后恶心呕吐常用干预方法有针刺、电针、经皮穴位电刺激、耳穴疗法、穴位注射、穴位按压、穴位贴敷等手段,针灸疗法不仅可以有效改善肿瘤患者胃肠道反应,而且对肿瘤患者生活质量、焦虑、抑郁等其他症状都有一定的改善作用,说明针灸疗法对肿瘤患者化疗产生的副作用具有较好的调节作用。     

中药减轻乳腺癌术后化疗毒副反应的临床观察

目的:观察中药对乳腺癌术后化疗毒副反应的辅助治疗作用。方法:将120例乳腺癌术后化疗患者随机分为观察组和对照组,对照组给予西药治疗,观察组给予中药治疗,第6个疗程化疗结束后比较两组患者恶心呕吐、骨髓抑制及生存情况。结果:观察组患者恶心呕吐和骨髓抑制发生率明显低于对照组(P<0.05),观察组生存情况明显好于对照组(P<0.05)。结论:中药在缓解乳腺癌术后化疗毒副反应方面有明显效果,可以提高患者抗癌能力和生活质量。     

格拉司琼用于抗肿瘤化疗所致恶心和呕吐的临床观察

目的:比较临床常规止吐治疗和加用格拉司琼在抗肿瘤化疗期间的止吐疗效.方法:选取100例恶性肿瘤患者随机分为对照组和观察组各50例 ,对照组在化疗期间给予泮托拉唑、甲氧氯普胺、维生素B6常规止吐治疗 ,观察组在此基础上加用格拉司琼3毫克 ,每日两次静脉注射 ,一天后停用甲氧氯普胺.而格拉司琼从化疗当日起使用一周.分别对两组患者化疗期间(化疗中和化疗后共计7天)进行呕吐频次、进餐频次、进餐量、体重、睡眠、药物副反应情况进行比较.结果:观察组各项指标好于对照组 ,对照组治疗有效率96% ,观察组治疗有效率72%.结论:格拉司琼用于治疗抗肿瘤化疗所致恶心呕吐的疗效比较理想 ,值得借鉴和推广.     

扶正祛邪法改善乳腺癌患者化疗毒副作用的临床观察

为观察扶正祛邪法对改善乳腺癌患化疗毒副作用的疗效。将60例乳腺癌化疗患分为两组。治疗组化疗期间接受中医治疗。对照组常规处理化疗期间的毒副反应。比较两组患在骨髓抑制、恶心呕吐、免疫功能、肝肾功能等方面的差异。结果：治疗组在白细胞抑制、恶心呕吐、部分细胞免疫指标方面均较对照组有明显改善。在心肌损害、肝肾功能及淋巴转移方面两组差异无显性意义。以扶正祛邪为原则的中医治疗可部分减轻乳腺癌患化疗毒副作用。提高其免疫功能。     

Electroacupuncture for control of myeloablative chemotherapy-induced emesis: A randomized controlled trial

CONTEXT: High-dose chemotherapy poses considerable challenges to emesis management. Although prior studies suggest that acupuncture may reduce nausea and emesis, it is unclear whether such benefit comes from the nonspecific effects of attention and clinician-patient interaction. OBJECTIVE: To compare the effectiveness of electroacupuncture vs minimal needling and mock electrical stimulation or antiemetic medications alone in controlling emesis among patients undergoing a highly emetogenic chemotherapy regimen. DESIGN: Three-arm, parallel-group, randomized controlled trial conducted from March 1996 to December 1997, with a 5-day study period and a 9-day follow-up. SETTING: Oncology center at a university medical center. PATIENTS: One hundred four women (mean age, 46 years) with high-risk breast cancer. INTERVENTIONS: Patients were randomly assigned to receive low-frequency electroacupuncture at classic antiemetic acupuncture points once daily for 5 days (n = 37); minimal needling at control points with mock electrostimulation on the same schedule (n = 33); or no adjunct needling (n = 34). All patients received concurrent triple antiemetic pharmacotherapy and high-dose chemotherapy (cyclophosphamide, cisplatin, and carmustine). MAIN OUTCOME MEASURES: Total number of emesis episodes occurring during the 5-day study period and the proportion of emesis-free days, compared among the 3 groups. RESULTS: The number of emesis episodes occurring during the 5 days was lower for patients receiving electroacupuncture compared with those receiving minimal needling or pharmacotherapy alone (median number of episodes, 5, 10, and 15, respectively; P<.001). The electroacupuncture group had fewer episodes of emesis than the minimal needling group (P<.001), whereas the minimal needling group had fewer episodes of emesis than the antiemetic pharmacotherapy alone group (P =.01). The differences among groups were not significant during the 9-day follow-up period (P =.18). CONCLUSIONS: In this study of patients with breast cancer receiving high-dose chemotherapy, adjunct electroacupuncture was more effective in controlling emesis than minimal needling or antiemetic pharmacotherapy alone, although the observed effect had limited duration. JAMA. 2000;284:2755-2761.     

清脂肝三联针穴位注射治疗中、重度酒精性脂肪肝的临床观察

目的 :探讨清脂肝三联针穴位注射治疗中、重度酒精性脂肪肝的临床疗效。方法 :穴位组 30例用清脂肝三联针穴位注射 ;对照组 2 0例不使用清脂肝三联针穴位注射。两组患者均给予血脂康胶囊、益肝灵片、维生素E等治疗。结果 :2组患者经过 4个月治疗后 ,穴位组治愈率、有效率及血清AST、ALT与治疗前及对照组治疗后比较 ,均有显著性差异 (P <0 .0 1) ,两组患者血清TC治疗后有明显下降 (P <0 .0 5 ) ,血清TG治疗后显著下降 (P <0 .0 1)。结论 :采用清脂肝三联针穴位注射治疗中、重度酒精性脂肪肝的疗效 ,明显优于单用祛脂保肝等药物的疗效。     

恩丹西酮联合维生素B6防治儿童化疗呕吐的疗效观察

目的观察恩丹西酮联合维生素比对儿童实体瘤化疗所致呕吐的疗效。方法42例化疗患者采用自身随机对照,分为AB组与BA组。AB组第一疗程为A方案,止吐治疗为每天化疗前静脉注射恩丹西酮5mg／m2配合维生素B6 4mg／kg静脉滴注;第Z-疗程为B方案,化疗前单纯静脉注射恩丹西酮5mg／m2。BA组则相反。均使用含顺铂方案化疗,A、B两疗程化疗方案一致。结果A方案化疗后控制急性呕吐和延迟性呕吐的有效率分别为90．5％,92．9％。B方案化疗后控制急性呕吐和延迟性呕吐的有效率分别为69．0％,73．8％。A方案止吐疗效明显优于B方案（P〈0．05）。副作用主要为便秘,两组发生率相似。结论恩丹西酮配合维生素民对儿童实体瘤化疗所致呕吐有协同防治的作用。     

艾易舒注射液联合化疗治疗非小细胞肺癌临床疗效观察

目的:观察斑蝥酸钠维生素B6注射液(艾易舒)对晚期肺癌患者化疗的协同治疗作用。方法:60例患者随机分为两组,治疗组30例,应用艾易舒合并化疗;对照组30例,单用化疗,比较两组抗肿瘤疗效、临床症状变化、化疗不良反应的发生情况。结果:治疗组30例,抗肿瘤有效率为40%,对照组30例,抗肿瘤有效率为33.3%;治疗组的症状改善率为86.7%,对照组的症状改善率为53.3%;治疗组KPS评分增高率为50.0%,对照组KPS评分增高率为23.3%;治疗组白细胞减少和消化道反应发生率分别为:30.0%、23.3%,对照组白细胞减少和消化道反应发生率分别为:46.7%、43.3%。结论:斑蝥酸钠维生素B6注射液具有增强化疗疗效、改善患者症状、减少化疗毒副反应的作用。     

针刺加TDP照射治疗遗尿56例临床分析

目的:探讨针刺加TDP照射治疗功能性遗尿的疗效.方法:对56例功能性遗尿的患者采用针刺加TDP照射治疗.按辨证分型取穴,肾阳不足型取穴百会、关元、中极、肾俞、膀胱俞及太溪,脾肺气虚型取穴百会、气海、太渊、足三里及三阴交,1～2疗程后观察疗效.结果:56例患者,治愈41例,好转13例,无效2例,总有效率为96.4%.结论:针刺加TDP照射治疗功能性遗尿疗效显著,治以补脾肺温肾阳.     

中西医结合三联疗法治疗慢性乙肝

使用口服抗病毒中药、穴位左旋咪唑涂布剂透皮吸收及穴位肌注干扰素三联疗法治疗慢性乙肝２６例，基本治愈１１例、显效１２例、有效２例、无效１例；在与单纯使用干扰素、中药、涂布剂３个对照组的疗效对比研究中，联合治疗组在主要病毒指标、肝功指标、症状指标三方面的疗效上，都取得了优于其它３个对照组的疗效，证明中西医结合多联疗法在治疗慢性乙肝方面更具优势。     

应用希罗达所致手足综合征的临床观察及护理

目的：观察塞来昔布联合维生素B6防治希罗达所致手足综合征的临床效果及护理措施。方法：将符合条件的恶性肿瘤患者82例随机分为观察组（42例）和对照组（40例）。两组化疗方案相同。观察组予以口服塞来昔布和维生素B6,同时给予对症及心理护理,对照组无预防性药物及给予常规护理。结果：观察组手足综合征发生率为11.9%,对照组手足综合征发生率为52.5%,两组比较,差异有高度统计学意义（χ2=15.592,P〈0.01）。结论：塞来昔布联合维生素B6可有效防治希罗达所致手足综合征的发生,及时的护理可明显缓解症状,缓解患者的紧张情绪,保护好皮肤,防止症状进一步发展。     

针灸对血管性痴呆中医证候的改善作用

Objective： To study the effects of acupuncture on Chinese medicine syndromes of vascular dementia （VaD）. Methods： Sixty-three VaD patients were divided into three groups. Those willing to be randomized were randomly assigned to receive either acupuncture （random acupuncture group, 24 cases） or rehabilitation training （guided rehabilitation group, 24 cases） for 6 weeks. Those unwilling to be randomized also received acupuncture for 6 weeks （non-random acupuncture group, 19 cases）. Patient syndromes and their severity were evaluated before treatment （baseline）, at the end of treatment, and at 4-week follow-up after the completion of treatment using a CM scoring system （scale of differentiation of syndromes of vascular dementia, SDSVD）. The SDSVD scores of the random and non-random acupuncture groups, and of all patients who received acupuncture （combined acupuncture group, 43 cases）, were compared with those in the guided rehabilitation group. Results： In the random, non-random, and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment and at follow- up than at baseline. In the guided rehabilitation group, SDSVD scores were similar to baseline scores at the end of treatment and at follow-up. However, there were no significant differences in SDSVD scores among the three groups or between the combined acupuncture group and the guided rehabilitation group at any time points. In the non-random and combined acupuncture groups, SDSVD scores were significantly reduced at the end of treatment than at baseline in patients with hyperactivity of Liver （Gan）-yang or phlegm obstruction of the orifices. Conclusions： Acupuncture reduced the severity of VaD. The improvement was the greatest in patients undergoing their treatment of choice. Treatments in this study were more effective for excess syndromes, such as Liver-yang hyperactivity or phlegm obstruction of the orifices than deficiency syndromes, such as Kidney （Shen）-essence deficiency.     

银质针联合梨状肌注射治疗梨状肌综合征的疗效

目的探讨银质针联合梨状肌注射治疗梨状肌综合征的治疗效果。方法梨状肌综合征患者60例,随机分为A组（31例）和B组（29例）。A组接受银质针联合梨状肌注射治疗,B组仅梨状肌注射治疗。分别于治疗后1周和3周及1个月时所有患者均行VAs评分,并按改良Mac—Nab标准评价疗效。结果A组治疗后各时点VAS评分均低于B组,差异均有统计学意义（P〈0．05）。A组治疗后3周和1个月时优良率分别为93．5％（29／31例）、87．1％（27／31例）均高于B组72．4％（21／29例）、58．6％（17／29例）,差异均有统计学意义（P〈0．05）。各组均未见明显并发症。结论银质针联合梨状肌注射治疗梨状肌综合征的效果优于单纯梨状肌注射治疗。     

针刺结合康复训练治疗中风偏瘫临床观察

[目的]探讨针刺结合康复训练疗法治疗中风偏瘫的有效性。[方法]50例中风偏瘫患者随机分为2组,治疗组25例,对照组25例,并进行疗效及神经功能缺损评定。[结果]治疗组总有效率为94·2%,对照组总有效率为80·7%,2组比较有显著差异(P<0·05);组间比较有显著差异(P<0·05),治疗前后神经功能缺损评分有显著差异(P<0·01),Asworth评定组间比较有显著差异(P<0·05)。[结论]针刺结合康复训练治疗中风偏瘫的疗效确切。