靶控输注异丙酚复合瑞芬太尼用于结肠镜检查的麻醉

目的 观察异丙酚靶控输注及复合瑞芬太尼在结肠镜检查监护麻醉中的静脉麻醉效能及其对呼吸循环功能的影响和药物的副作用.方法 60例患者,随机分为异丙酚靶控输注瑞芬太尼组(A组)及单纯异丙酚靶控输注组(B组),记录诱导、插镜、苏醒及留现时间,记录各时点MAP,HR,SpO2,RR,记录术中肢动,呼吸暂停等副作用,随访患者满意度.结果 A组诱导时间明显短于B组(P＜0.05),T1,T2点B组MAP低于A组(P＜0.05),术中A组肢动明显少于B组(P＜0.05),呼吸暂停A组多于B组(P＜0.05),A组患者对镇静镇痛的满意度高于B组.结论 异丙酚靶控输注复合瑞芬太尼静脉麻醉的效果确切,术后苏醒迅速,并发症少.     

瑞芬太尼复合异丙酚在小儿麻醉中的临床观察

目的 观察瑞芬太尼复合异丙酚在小儿麻醉中对血流动力学和并发症的影响.方法 选择60例手术患儿随机分为两组,每组30例.麻醉诱导采用静脉注射异丙酚、维库溴铵、咪唑安定、瑞芬太尼或芬太尼,气管插管全麻.麻醉维持:A组持续静脉泵注瑞芬太尼和异丙酚,B组持续静脉泵注芬太尼和异丙酚.观察诱导前、诱导后1 min、气管插管后2、5 min MAP、HR的变化,同时观察麻醉效果、麻醉苏醒时间及不良反应等情况.结果 麻醉诱导后1 min,A、B两组MAP、HR均有所降低(P＜0.01),但在正常范围.插管后2、5 min与诱导后1 min比较,A组MAP、HR变化不大(P＞0.05),B组变化明显(P＜0.01).两组清醒时间、拔管时间A组短于B组(P＜0.01);拔管后呼吸道梗阻、SpO2＜90%A组低于B组(P＜0.05),但躁动发生率A组高于B组(P＜0.05).结论 瑞芬太尼复合异丙酚在小儿插管全麻中有效性和安全性优于芬太尼复合异丙酚.     

瑞芬太尼复合丙泊酚靶控输注在小儿扁桃体摘除术麻醉中的应用

目的 观察瑞芬太尼复合丙泊酚靶控输注(TCI)应用于小儿扁桃体摘除术的麻醉效果.方法 选择择期行扁桃体摘除术小儿80例,随机分为观察组(A组,n=40)和对照组(B组,n=40),A组采用瑞芬太尼和丙泊酚靶控输注(TCI)诱导和维持.B组采用丙泊酚和芬太尼诱导,异氟烷吸入维持.观察记录术中循环功能、清醒时间及术后不良反应.结果 A组术中循环功能相对稳定,平均动脉压(MAP)和心率(HR)在置入开口器时、扁桃体切除时及拔管时的即刻值与B组同时点值相比波动较小,有统计学意义(P<0.05).A组清醒时间与苏醒期不良反应发生与B组比较有统计学意义(P<0.05).结论 瑞芬太尼复合丙泊酚TCI全凭静脉麻醉(TIVA)可以为小儿扁桃体摘除术提供稳定的血流动力学状态,术后清醒完全迅速且质量满意.     

异丙酚靶控输注复合瑞芬太尼全凭静脉麻醉的效果观察

目的探讨异丙酚靶控输注复合瑞芬太尼全凭静脉麻醉的临床效果。方法40例ASA I~Ⅱ级择期行腹部手术的病人随机分为异丙酚靶控输注复合瑞芬太尼组(PR,20例)和异丙酚靶控输注复合芬太尼组(PF,20例)进行麻醉。记录两组麻醉前、诱导后、插管时、切皮时、手术开始后30m in和60m in及术毕时病人的平均动脉压(MAP)、心率(HR)以及术后的恢复情况。结果PF组术中MAP、HR均高于PR组,应激反应较大;PF组术后呼吸恢复时间、拔管时间晚于PR组。结论异丙酚靶控输注复合瑞芬太尼全凭静脉麻醉对血流动力学影响小,术后恢复快,是一种较为适宜的麻醉方法。     

瑞芬太尼、异丙酚全凭静脉麻醉在小儿腺样体切除手术中的应用

目的:比较瑞芬太尼、异丙酚全凭静脉麻醉用于小儿麻醉与静吸复合麻醉对血流动力学的影响.方法:选择30例行腺样体切除术的患儿随机分为全静脉麻醉(A)组和静吸复合麻醉(B)组,每组15例,A组静脉输注瑞芬太尼、异丙酚全凭静脉麻醉维持, B组吸入异氟醚及静脉输注异丙酚维持麻醉,记录术中的血压(BP)、心率(HR)、脉搏氧饱和度(SpO2).结果:B组术中的HR较A组增快.结论:瑞芬太尼、异丙酚全凭静脉麻醉用于小儿与静吸复合麻醉比较是一种较好的麻醉方法.     

异丙酚靶控输注复合瑞芬太尼在纤维支气管镜检查中的应用

目的观察异丙酚靶控输注及复合瑞芬太尼在纤维支气管镜检查监护麻醉中的静脉麻醉效能，及其对呼吸、循环功能的影响和药物的不良反应。方法42例患者，随机分为异丙酚靶控输注复合瑞芬太尼组（A组）及单纯异丙酚靶控输注组（B组）。在不同时间点监测平均动脉压（MAP），心率（HR），脉搏血氧饱和度（SpO2）。记录不良反应。结果A组诱导时间明显短于B组（P〈0．05），T1、T2点B组MAP低于A组（P〈0．05），术中A组肢动明显少于B组（P〈0．05），呼吸暂停A组多于B组（P〈0.05），A组病人对镇静镇痛的满意程度高于B组。结论异丙酚靶控输注复合瑞芬太尼静脉麻醉的效果确切、术后苏醒迅速，并发症少。     

异丙酚复合瑞芬太尼在无痛流产术中的应用

目的 探讨异丙酚复合瑞芬太尼用于无痛流产的麻醉效能.方法 120例拟行无痛流产的病人,随机分为2组,每组60例.术中A组仅单纯靶控输注(TCI)10 g/L的异丙酚,设定血浆靶浓度为8.0 mg/L;B组在输注异丙酚前1 min给予瑞芬太尼0.4 μg/kg体质量,并设定异丙酚的血浆靶浓度为5.0 mg/L.监测生命体征的变化、呼吸抑制程度、苏醒时间、术中体动情况、术后宫缩痛时间及异丙酚的用量等.结果 两组病人呼吸抑制发生率、苏醒时间比较差异无显著性(P>0.05).术中体动发生率、术后宫缩痛发生率及异丙酚用量B组明显减少(χ2=24.51、22.32,t=84.60,P＜0.01).结论 异丙酚复合瑞芬太尼用于无痛流产明显改善了术中体动及术后宫缩痛,并减少了异丙酚的用量,使无痛人工流产术更加安全有效.     

异丙酚联合瑞芬太尼靶控输注在胃镜诊疗中的应用研究

目的研究异丙酚静注联合应用瑞芬太尼靶控输注(TCI)在胃镜诊疗中的镇静效果和安全性。方法实行无痛胃镜诊疗的60例患者,随机分为2组,分别予以异丙酚静注联合瑞芬太尼靶控输注(RP组)和单纯静注异丙酚镇静(P组),观察诱导前、进镜时、诊疗时及术毕时BIS、SpO2、平均动脉压(MAP)、HR的变化以及比较检查操作时间、意识消失时间、意识恢复时间、异丙酚用量。结果与诱导前相比,2组术中BIS降低(P<0.05),P组术中MAP和HR及术毕时HR降低(P<0.05)。与P组比较,RP组术中BIS升高(P<0.05),MAP、HR、SpO2差异无显著性。结论瑞芬太尼靶控输注联合异丙酚静注用于胃镜检查及治疗时,麻醉迅速、平稳,苏醒快,镇静效果满意。     

喉罩吸入七氟醚复合瑞芬太尼麻醉在小儿腹股沟疝手术中的应用

目的 比较喉罩吸入七氟醚复合瑞芬太尼麻醉与异丙酚复合氯胺酮静脉麻醉在小儿腹股沟疝手术中应用的优劣.方法 择期腹股沟疝手术患儿40例,ASA Ⅰ级,随机分为喉罩吸入七氟醚复合瑞芬太尼组(A组)和异丙酚复合氯胺酮组(B组),每组20例.术中均保留自主呼吸,记录呼吸循环变化、诱导和苏醒时间、术中体动和术后不良反应发生率.结果 B组切皮后15min和术毕时HR明显快于A组和诱导前(P＜0.05),B组患儿术中体动反应、术后不良反应发生率明显高于A组(P＜0.05),在诱导时间、苏醒时间上A组较B组明显缩短(P＜0.05).结论 对于腹股沟疝手术患儿,喉罩吸入七氟醚复合瑞芬太尼麻醉比异丙酚复合氯胺酮静脉麻醉效果更好.     

异丙酚复合瑞芬太尼气管插管与复合氯胺酮非气管插管麻醉在烧伤手术中的比较

目的 比较异丙酚复合瑞芬太尼气管插管与复合氯胺酮非气管插管麻醉在烧伤手术中的特点.方法 60例择期烧伤手术病人,ASAⅠ-Ⅱ级,按序贯实验分为氯胺酮组(A组)和瑞芬太尼组(B组),每组30例.A组麻醉诱导用安定和氯胺酮,维持麻醉用微量泵持续输注异丙酚和氯胺酮,术中保留自主呼吸并用鼻导管给氧;B组麻醉诱导用安定、阿曲库铵、丙泊酚、瑞芬太尼,气管插管后行机械通气,维持麻醉用微量泵持续输注瑞芬太尼、丙泊酚、阿曲库铵.观察麻醉前、麻醉诱导后、手术开始时、术中45 min、术毕5 min各时点的平均动脉压(MAP)、HR和SpO2的变化以及术后苏醒时间和术中、术毕时出现的不良反应.结果 麻醉诱导后A组MAP明显增高(P＜0.05),而B组MAP显著下降(P＜0.05);2组比较,差异也有统计学意义P<0.05);麻醉诱导后A组SpO2明显下降(P＜0.05),而B组SpO2稍有增高(但P＞0.05);B组苏醒时间明显比A组短(P<0.01);A组术中易发生躁动、谵妄和呼吸抑制等不良反应.结论 异丙酚复合瑞芬太尼气管插管麻醉用于烧伤手术,呼吸循环稳定,苏醒及时,不良反应少,提高了麻醉的安全性,且便于麻醉管理.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.     

Development Is A High Level Inheritance for China Time-honored Brand Products

<正>As culture is the soul of a nation,the three books,"History of Chinese Philosophy,""History of Chinese Culture"and"History of Chinese Science and Technology"have demonstrated the superiority of our great Chinese culture,and its significant impact in the field of international culture.Both core value and practical value of the Chinese culture are very clear,reflected in the views of universe,nature,life,health,disease,and therapy and related considerations,concepts,and technical methods.