糖尿病患者生存质量影响因素分析

目的 了解糖尿病患者生存质量、社会支持及伴发焦虑、抑郁的现状,探讨其相关的影响因素.方法 应用糖尿病人生存质量特异性量表(DSQL)、社会支持量表(SSRS)、焦虑自评量表(SAS)、抑郁自评量表(SDS),对504例糖尿病患者进行调查.结果 糖尿病对健康的损害率为95.64%,对心理、人际关系的影响率为76.19%、30.36%;伴发焦虑、抑郁的比例为11.31%、29.96%;生存质量与病程等因素显著相关(r=0.18～0.55,P＜0.01);社会支持与年龄等因素显著相关(r＞0.11,P＜0.01);焦虑、抑郁与并发症等因素显著相关(r＞0.20,P＜0.01);生存质量、社会支持、焦虑、抑郁在病程、并发症等变量的不同水平之间差异有显著性(P＜0.05).结论 并发症、伴发焦虑、抑郁是影响患者生存质量的主要因素,预防和控制并发症,改善不良情绪是提高生存质量的关键.     

产妇焦虑和抑郁影响因素的Logistic回归分析

目的探讨济宁市产妇心理特征，分析其影响因素，为围产期妇女的健康教育和护理提供依据。方法采用自制一般状况问卷、焦虑自评量表及抑郁自评量表对济宁市中区三所医院中住院的所有产妇进行问卷调查。结果505名产妇中，抑郁情绪的发生率为26．5％，焦虑者占18．8％。文化程度（r=-0．148，P〈0．01）、别人的照顾（r=-0．0178，P〈0．01）、职业是产后焦虑、抑郁情绪的保护性因素而担心手术影响胎儿智力（r=0．167，P〈0．01）、分娩方式是产后焦虑、抑郁情绪的危险因素。结论产妇焦虑、抑郁情绪发生率较高，对围产期妇女进行卫生保健和心理护理工作尤为重要。     

铁路职工焦虑抑郁情绪与人格特征、社会支持的相关性研究

目的：探讨铁路职工焦虑抑郁情绪、人格特征、社会支持及其相互关系。方法：采用分层整群随机抽样的方法，抽取302名济南铁路分局铁路职工。对所抽样本进行焦虑自评量表（SAS）、抑郁自评量表（SDS）、艾森克个性问卷（EPQ），社会支持评定量表（SSRS）的调查。结果：铁路职工焦虑、抑郁的发生率分别为18．5％、35．1％，男性焦虑发生率为21．6％、女性为2．1％。女性获得的社会支持要多于男性（P〈0．01）。铁路职工的情绪偏向于不稳定性。SAS、SDS得分与EPQ—N、EPQ—P得分呈显著正相关，与SSRS总分呈显著负相关（P均〈0．01）。结论：铁路职工有着较多的焦虑抑郁情绪，且人格特征、社会支持对铁路职工焦虑抑郁情绪具有重要的影响作用。应积极采取干预措施，提高其情绪调节的能力、社会支持水平及社会支持利用度，从而缓解不良情绪，提高生活质量。     

567例门诊性病患者焦虑情绪的调查

目的：为了探索性病患者伴发的焦虑情绪及影响焦虑的有关因素。方法：随机选择某皮肤科门诊患者567例，采用焦虑自评量表（SAS）、抑郁自评量表（SDS）及自拟问卷进行调查。结果：该组性病患者的焦虑、抑郁自评量表的平均粗分与正常人群国内常模比较差异有显著性（P〈0．01）；诊断为性病患者的焦虑分值与诊断为非性病患者比较差异也有显著性（P〈0．01）。结论：在治疗性病患者的同时，应开展性生理咨询、心理治疗并可适时应用抗焦虑剂，有利于患者早日康复。     

284例门诊女性性病患者焦虑情绪的调查

目的探索女性性病伴发的焦虑情绪及影响焦虑的有关因素。方法随机选择某皮肤科门诊女性284例，采用焦虑自评量表（SAS）、抑郁自评量表（SDS）及自拟问卷进行调查。结果该组女性性病患者的焦虑、抑郁自评量表的平均粗分与正常人群国内常模比较差异有显著性（P〈0．01）；诊断有性病的女性患者的焦虑分值与诊断为非性病女性患者比较差异也有显著性（P〈0．01）。结论在治疗女性性病患者的同时。应开展性生理咨询、心理治疗并可适时应用抗焦虑剂。     

护理干预对心脏瓣膜手术患者焦虑、抑郁状态的影响

目的观察护理干预对中青年心脏瓣膜手术患者焦虑、抑郁状态的影响。方法采用焦虑自评量表（SAS）和抑郁自评量表（SDS）对80例中青年心脏瓣膜手术患者在护理干预前后进行调查。结果护理干预前患者焦虑、抑郁人数分别为60例（75．00oA）与65例（81．25％）,护理干预后焦虑、抑郁人数分别为16例（20．00％）与12例（15．00％）,干预前后比较,均P〈0．01,差异有统计学意义;干预前后患者焦虑、抑郁分值比较,均P〈0．01,差异有统计学意义。结论心理护理、争取社会支持等护理干预能有效减轻中青年心脏瓣膜手术患者焦虑、抑郁程度,促进患者康复。     

脑卒中患者心理健康和生活方式的对照研究

目的探讨社会心理因素、心理健康状况、生活方式与脑卒中的病因学联系。方法对86例脑卒中患者和85例正常人应用简明智能状况检查表、生活事件量表、社会支持评定量表、症状自评量表、焦虑自评量表、抑郁自评量表，生活方式问卷测查表和一般情况调查表进行对照调查。结果与正常组对照，脑卒中组负性生活事件分更高（t=10．17，P〈0．01），社会支持度更低（t=3．83，P〈0．01）；心理健康状况方面脑卒中组在焦虑，抑郁，强迫，敌对，人际敏感，恐怖，偏执，躯体化精神病性等因子分均明显高于对照组（t=3．15～11．56，P〈0．05～0．01）；生活方式方面，脑卒中组在饮食不良习惯、业余生活单调、缺乏锻炼，嗜烟酒，睡眠无规律等均明显高于对照组（χ^2=5．62～17．37，P〈0．05～0．01）。结论负性生活事件多发，缺乏亲人和社会支持，心理健康状况差和不良的生活方式可能是脑卒中发生发展的危险因素。     

支持性心理治疗对系统性红斑狼疮患者的情绪障碍疗效分析

将84例系统性红斑狼疮（SLE）患者随机分为两组，对照组用常规治疗护理；治疗组在此基础上加支持性心理治疗。用抑郁自评量表（SDS）及焦虑自评量表（SAS）对患者入院时和住院治疗2周后的焦虑抑郁状态分别进行评定。探讨SLE患者抑郁焦虑发生的特点及支持性心理治疗对SLE住院期间消除抑郁焦虑的效果。结果：治疗前两组患者约84％有抑郁，约53％有焦虑。治疗后两组SDS、SAS评分均有改善。治疗后对照组抑郁焦虑评分下降无显著性（P〉0．05），而治疗组焦虑抑郁改善非常显著（P〈0．01）。提示支持性心理治疗有助于SLE患者焦虑抑郁状态的改善。     

糖尿病视网膜病变患者抑郁状况分析

目的探讨糖尿病视网膜病变患者抑郁状况及影响因素。方法对2003年至2005年在内分泌科住院的72例2型糖尿病患者进行基础资料采集，并在医师指导下完成艾森克个性问卷（EPQ）、社会支持度评定量表（SSRS）、焦虑自评量表（SAS）、抑郁自评量表（SDS）。然后对视网膜病变组及无视网膜病变组患者的资料进行对比分析。结果2组患者在病程、个性特征、客观支持分、对支持的利用度和焦虑分等方面的差异无统计学意义（P均〉0．05）；视网膜病变组患者SSRS总分、主观支持分低于无视网膜病变组（P均〈0．05）；年龄、餐后血糖、抑郁指数高于无视网膜病变组（P均〈0．05），抑郁发生率高、程度重，差异有统计学意义。结论糖尿病视网膜病变患者抑郁发生率高，程度重，主观支持分低。     

膀胱癌术后灌注患者心理健康、社会支持及生存质量研究

目的探讨膀胱癌术后灌注患者的心理健康状况、社会支持情况及生存质量。方法用症状自评量表（SCL-90）、社会支持评定量表（SSRS）及世界卫生组织生存质量量表简表（WHOQOL—BREF）对82例膀胱癌术后灌注患者（灌注组）进行调查分析,并与泌尿科普通就诊患者（普通组）进行比较分析。结果①灌注组在SCL-90中的躯体化、人际关系敏感、焦虑、抑郁、恐怖因子显著高于普通组（P〈0．01）;②灌注组在SSRS中的社会支持总分、客观支持、社会支持的利用度评分显著低于普通组（P〈0．01）;③灌注组在WHOQOL—BREF中的总体评价、生理领域、心理领域、社会关系评分显著低于普通组（P〈0．01）。结论膀胱癌术后灌注患者存在有明显的躯体化、人际敏感、抑郁、焦虑、恐怖等不良心理健康状况,在社会中所获得的支持程度和对支持的利用度均较低,生存质量较差。     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.