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1.
Background  Few studies have used body mass index (BMI), waist-to-hip ratio (WHR) and waist circumference (WC) at the same time to investigate the association between obesity and colorectal adenoma. This study examined the strength of association between colorectal adenoma and obesity using not only BMI, but also WHR and WC.
Methods  Subjects of this study included 1322 asymptomatic patients who underwent colonoscopy for cancer screening from January 2006 to June 2008. Anthropometric measurements, blood test results, and a self-administered questionnaire from each subject were analyzed.
Results  Four hundred and fourteen adenoma cases were identified in 1322 subjects. Using univariate analysis, the prevalence of adenoma was associated with BMI and WHR and was higher among the abdominal obesity group using WC guidelines of the Korean Society for the Study of Obesity, but not using WC guidelines of the International Diabetes Federation. In multiple Logistic regression analysis, general obesity (BMI ≥25 kg/m2) increased the risk of colorectal adenoma (odds ratio (OR), 1.43; 95% confidence interval (CI), 1.05–1.94). Also, abdominal obesity by the WC cutoffs and the highest WHR percentile group (WHR ≥0.95) were significantly associated with adenoma. Among three measures of obesity, however, only BMI had a persistent association with adenoma after adjusting reciprocally for BMI, WC, and WHR (OR, 1.30; 95% CI, 1.02–1.80; and 1.49; 1.06–2.10, adjusted for WC and WHR, respectively).
Conclusion  The data suggest that general obesity is associated with an increased risk of colorectal adenoma.
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2.
Objective To compare the application of two different definitions of MS (IDF2005 and ATP Ⅲ 2001)in this study population.Accroding to IDF2005.evaluate the impact of body fat content and its distribution for the risk of metabolic syndrome.Methods The sample of 818 subiects maseaure the simple anthropometric parameters including body mass index(BMI),waist circumference,waist-hip ratio (WHR),and so on. Body fat mass and distribution were measured by dual-energy X-ray abosorbtiometry (DEXA).Quatile method is used to analyse the relevance ratio of MS in different value of BF and TF.ROC curve is used in evaluating of tipping point of BF,TF,simple body composition parameters and reliability of diagnosis.The risk of MS were analyzed by logistic regression.Results According to IDF2005,when BF,TF≥P50.the relevance ratio of MS has a remarkable increasing(P<0.01),its matching BMI is 24 and 23 kg/m2,according to NCEP ATPⅢ2001,when BF、TF≥P75,the relevance ratio of MS has a remarkable increasing,too(P<0.01),its matching BMI value is 26 kg/m2,BF and TF of MS patients which diagnosed by IDF2005 are lower than ATPⅢ2001(P<0.05).For each additional level of BF,the odds ratios of MS prevalence were 1.952(male) and 2.644(female);for each additional level of TF,the odds ratios of MS prevalence were 3.276(male) and 3.058(female),BMI,WHR were not into the equation.The AUCROC which used to evaluate the exist of MS by BF and TF is larger than 0.9.and has better performance in sensitivity and specificity than BMI and WHR;the best point of contact of MS in BF is 25%(male),35% (female),in TF is 30%(male),38%(female).Conclusion ATPⅢ standards may have been mi8Sed MS patients with normal high fasting blood glucose value and abdominal obesity.The applicaton of IDF2005 standards was proved better in this populatin.Compared with simple anthropometric parameters,the accmulation of body fat,especially trunk fat even more harmful,to is better to identify the risk of MS in Fuzhou adults population.  相似文献   

3.
Objective To compare the application of two different definitions of MS (IDF2005 and ATP Ⅲ 2001)in this study population.Accroding to IDF2005.evaluate the impact of body fat content and its distribution for the risk of metabolic syndrome.Methods The sample of 818 subiects maseaure the simple anthropometric parameters including body mass index(BMI),waist circumference,waist-hip ratio (WHR),and so on. Body fat mass and distribution were measured by dual-energy X-ray abosorbtiometry (DEXA).Quatile method is used to analyse the relevance ratio of MS in different value of BF and TF.ROC curve is used in evaluating of tipping point of BF,TF,simple body composition parameters and reliability of diagnosis.The risk of MS were analyzed by logistic regression.Results According to IDF2005,when BF,TF≥P50.the relevance ratio of MS has a remarkable increasing(P<0.01),its matching BMI is 24 and 23 kg/m2,according to NCEP ATPⅢ2001,when BF、TF≥P75,the relevance ratio of MS has a remarkable increasing,too(P<0.01),its matching BMI value is 26 kg/m2,BF and TF of MS patients which diagnosed by IDF2005 are lower than ATPⅢ2001(P<0.05).For each additional level of BF,the odds ratios of MS prevalence were 1.952(male) and 2.644(female);for each additional level of TF,the odds ratios of MS prevalence were 3.276(male) and 3.058(female),BMI,WHR were not into the equation.The AUCROC which used to evaluate the exist of MS by BF and TF is larger than 0.9.and has better performance in sensitivity and specificity than BMI and WHR;the best point of contact of MS in BF is 25%(male),35% (female),in TF is 30%(male),38%(female).Conclusion ATPⅢ standards may have been mi8Sed MS patients with normal high fasting blood glucose value and abdominal obesity.The applicaton of IDF2005 standards was proved better in this populatin.Compared with simple anthropometric parameters,the accmulation of body fat,especially trunk fat even more harmful,to is better to identify the risk of MS in Fuzhou adults population.  相似文献   

4.
Objective Central obesity is considered to be a central component of metabolic syndrome. Waist circumference(WC) has been widely used as a simple indicator of central obesity. This study is aimed to evaluate the sensitivity of WC cut-off values for predicting metabolic risk factors in middle-aged Chinese. Methods The study involved 923 subjects aged 40-65 years. The metabolic risk factors were defined according to the Chinese Joint Committee for Developing Chinese Guidelines on Prevention and Treatment of Dyslipidemia in Adults. WC cut-off 85-90 cm and ≥90 cm were used as cut-off values of central pre-obesity and central obesity in males, respectively, while WC 80-85 cm and ≥85 cm were used as cut-off values of central pre-obesity and central obesity in females. Results First, WC values corresponding to body mass index(BMI) 24 kg/m2 and visceral fat area(VFA) 80 cm2 were 88.55 cm and 88.51 cm in males, and 81.46 cm and 82.51 cm in females respectively. Second, receiver operating characteristic curves showed that the optimal WC cut-off of value was 88.75 cm in males, higher than that in females(81.75 cm). Third, the subjects with higher WC values were more likely to have accumulating metabolic risk factors. The prevalence of metabolic risk factors increased linearly and significantly in relation to WC levels. Conclusion WC cut-off values of central pre-/central obesity are optimal to predict multiple metabolic risk factors.  相似文献   

5.
Objective To compare dietary intake and composition of women with and without polycystic ovary syndrome (PCOS), and finally to figure out the relationship between dietary intake and PCOS. Methods Eighty-six women attending an outpatient gynecological endocrinology unit, underwent evaluation of anthropometry, dietary intakes by means of a food frequency questionnaire (FFQ), 47 women with PCOS and 39 age-matched control women were investigated. Dietary intake was assessed by 24 h recalls. Associations between nutrients, BMI, WHR and glycometabolic measurements of PCOS were analyzed using multiple linear correlation and multiple linear regression analysis. Results 1) Obesity PCOS patients (BMI≥25 kg/m2) took significantly more carbohydrates (P<0.05) and fat (P<0.01) of diet than the control women in 24 h before the first visit. There was significantly lower ratio of protein (P<0.01) and higher ratio of lipid (P<0.01) in obesity PCOS patients than those in the control. Obesity PCOS women took significantly more calories (P<0.05) and higher ratio of lipid (P<0.01) than non-obesity PCOS women (BMI<25 kg/m2). There were no significantly statistical differences between the non-obesity PCOS women and controls. 2) There were positive correlations between BMI and energy lipid intake, but negative correlations between BMI and the ratio of protein in the diet intake (P<0.05). In PCOS women, fasting insulin (FINS), area under curve of insulin (IAUC), and homeostasis model assessment of insulin resistance (HOMA-IR) were all positively related with BMI (all P<0.05). 3) Multiple stepwise regression analysis showed that BMI was positively associated with the amount of fat and negatively associated with the ratio of protein in diet in 24 h (both P<0.001). HOMA-IR was positively related with fat intake and negatively related with protein composition (both P<0.05). Conclusion The statistical differences exist in the nutritional composition of obesity PCOS patient’s diets, which may contribute to obesity PCOS development.  相似文献   

6.
Objective To assess the obesity prevalence in Saudi adults according to the international standards of body mass index (BMI) and body fat percentage (BF%). Methods Five hundred and thirty healthy Saudi adults aged 18-72 years (mean 36.91±15.22 years) were enrolled in this study. Their body composition was assessed by bioelectrical impendence analysis with a commercially available body composition analyzer. Standard BMI and BF% values were used to define obesity. Results The prevalence of underweight, normal underweight, overweight and obesity in Saudi adults according to the BMI criteria (<18.5 kg/m 2 , 18.5-24.4 kg/m 2 , 25-29.9 kg/m 2 , 30 kg/m 2 and above, respectively) was 2.5%, 30.2%, 33.6%, and 33.8%, respectively, whereas the obesity prevalence was 60% (n=318) in Saudi adults according to the BF% criteria (25% for males and 30% for females), which was significantly higher than that according to BMI criteria. However, it was 50.6% (n=268) when the BMI cutoff point was 27.5 kg/m 2 , proposed by WHO for the Asian population. Kappa analysis showed that the obesity prevalence defined by BMI and BF% was higher in females than in males (k=0.530 vs k=0.418, P<0.0001). The sensitivity and specificity of BMI (30 kg/m 2 and 27.5 kg/m 2 ) were 54.1% and 96.7% and 76.4% and 88.2%, respectively, for obesity. A lower BMI cutoff point (26.60 kg/m 2 ) was proposed in this study, which gave the maximum sensitivity (84.3%) and specificity (85.4%), with a moderate kappa agreement (k=0.686). Moreover, the obesity prevalence at this cutoff point (56.4%) was significantly higher than that recommended by WHO. Conclusion The specificity of BMI for obesity is high and its sensitivity is low in both sexes. Its sensitivity can be increased by changing BMI cutoff to a lower value. The choice of BF% reference is of great influence for the assessment of obesity prevalence according to the BMI.  相似文献   

7.
Objective To examine the association between habitual sleep duration and obesity among Chinese adults. Methods The association of sleep duration and obesity was investigated among 7,094 community-dwelling Chinese adults. Sleep duration was self-reported. In this study, obesity was defined as follows: body mass index(BMI) ≥ 28 kg/m~2, waist circumference(WC) ≥ 85 cm in men and ≥ 80 cm in women, and percent body fat(%BF) ≥ 25 in men and ≥ 35 in women. Logistic and quantile regressions were employed to examine relationships of interest. Results Overall, 6.42% of the participants reported short sleep durations( 6 h/d) while 14.71% reported long(≥ 9 h/d) sleep durations. Long sleepers(≥ 9 h/d) represented a greater frequency of women with obesity [odds ratio(OR): 1.30; 95% confidence interval(CI), 1.02-1.67] and high body fat(1.43, 1.04-1.96) than those who slept 7-8 h/d. An association between long sleep times and higher BMI estimations was found across the 10~(th)-75~(th) percentile of the BMI distribution. Among men, long sleepers(≥ 9 h/d) presented lower risks of developing abdominal obesity compared with individuals who slept 7-8 h/d(OR = 0.79, 95% CI: 0.44-0.99). Conclusion Our study suggests that long sleep durations are associated with general obesity in Chinese women but reduced waist circumferences in men. Confirmatory studies are needed to determine the heterogeneous association of sleep time and obesity by gender.  相似文献   

8.
<正>The aim of the study was to investigate whether the expression of obestatin in gastric body mucosa in abdominal obesity patients with norma body mass index(BMI)is different compared with healthy controls.Twenty abdominal obesity patients with normal BMI and twenty healthy controls were included in the study.The number of  相似文献   

9.
Objective To explore the impacts of types and degree of obesity on non‐alcoholic fatty liver disease (NAFLD) and related lipids disturbance in Chinese school‐age children. Methods A total of 1 452 school‐age Children of 7 to 17 years were recruited in Beijing with representative cluster sampling method. Data of anthropometric measurements including weight, height and waist circumference were collected from March to May of 2007. Body mass index(BMI)was calculated. Blood samples were obtained and lipid profil...  相似文献   

10.
Objective To investigate acrylamide(ACR)-induced subacute neurotoxic effects on the central nervous system(CNS) at the synapse level in rats. Methods Thirty-six Sprague Dawley(SD) rats were randomized into three groups,(1) a 30 mg/kg ACR-treated group,(2) a 50 mg/kg ACR-treated group, and(3) a normal saline(NS)-treated control group. Body weight and neurological changes were recorded each day. At the end of the test, cerebral cortex and cerebellum tissues were harvested and viewed using light and electron microscopy. Additionally, the expression of Synapsin Ⅰ and P-Synapsin Ⅰ in the cerebral cortex and cerebellum were investigated. Results The 50 mg/kg ACR-treated rats showed a significant reduction in body weight compared with untreated individuals(P 0.05). Rats exposed to ACR showed a significant increase in gait scores compared with the NS control group(P 0.05). Histological examination indicated neuronal structural damage in the 50 mg/kg ACR treatment group. The active zone distance(AZD) and the nearest neighbor distance(NND) of synaptic vesicles in the cerebral cortex and cerebellum were increased in both the 30 mg/kg and 50 mg/kg ACR treatment groups. The ratio of the distribution of synaptic vesicles in the readily releasable pool(RRP) was decreased. Furthermore, the expression levels of Synapsin Ⅰ and P-Synapsin Ⅰ in the cerebral cortex and cerebellum were decreased in both the 30 mg/kg and 50 mg/kg ACR treatment groups. Conclusion Subacute ACR exposure contributes to neuropathy in the rat CNS. Functional damage of synaptic proteins and vesicles may be a mechanism of ACR neurotoxicity.  相似文献   

11.
腹内脂肪面积切点与代谢综合征临床检出率的关系   总被引:13,自引:0,他引:13  
Chen J  Tian ZQ  Zhang WG  Chen JH  Yan ZC  Ni YX  Zhong J  Jin J  Zhao ZG  Mu H  Zhu ZM 《中华医学杂志》2006,86(30):2110-2113
目的探讨估测代谢综合征(MS)的腹内脂肪面积(VA)的切点,以及VA与代谢综合征检出率的关系。方法应用螺旋CT检测了564例代谢综合征、糖尿病和高血压病病人的腹内脂肪面积;分别应用ROC工作曲线和四分位法分析估测代谢综合征及其组分的VA临界点和该临界点所对应的简易体脂参数包括,体重指数(BMI)、腹围(WC)和腰臀比(WHR),以及不同VA面积下的代谢综合征的检出率。结果(1)女性病人出现血脂紊乱、腹型肥胖和代谢综合征时VA集中在70~72cm。之间,而男性病人出现以上代谢紊乱时VA多在91~107cm^2之间,未找到高血糖和高血压相应的VA切点。(2)罹患代谢紊乱时,女性腹围在82~84cm之间,BMI在24~25kg/m^2之间;男性腹围在89cm左右,BMI在25kg/m^2左右。(3)男性VA在70cm^2、71~101cm^2、102~133cm^2、≥134cm^2时代谢综合征检出率分别为16.9%、49.4%、72.7%和87.5%,VA≥70cm^2时代谢综合征检出率显著增高(P〈0.01);女性VA在〈55cm^2、55~84cm^2、85~104cm^2、≥105cm^2时代谢综合征检出率分别为7.7%、44.0%、67.2%和87.5%,VA≥55cm^2时代谢综合征检出率显著增高(P〈0.01)。结论代谢综合征病人腹内脂肪的堆积有性别差异;在临界超重或超重阶段,即已出现腹内脂肪堆积及各种代谢紊乱的聚集;随着腹内脂肪含量的增加,代谢综合征的临床检出率显著升高。  相似文献   

12.
腹型肥胖内脏脂肪定量检测的评估及其临床意义   总被引:5,自引:0,他引:5  
目的 分析临床常用体脂检测方法与内脏脂肪型肥胖(VFO)诊断切点的相关性,及其在判断腹型肥胖类型中的价值.方法 4301例研究对象,其中659例接受了CT、生物电阻抗(体脂仪)和B超3项检查.以CT检查确定的腹内脂肪面积(VA)≥100 cm2作为判断VFO的诊断标准,应用受试者工作特征(ROC)曲线分别分析简易体脂参数(腰围、体重指数、腰臀比),体脂仪参数(全身脂肪含量、全身脂肪重量),超声测值(腹壁脂肪厚度、腹内脂肪厚度)判断VFO的切点及其敏感性和特异性.结果 (1)腰围、脂肪重量、体重指数、腹内脂肪厚度、全身脂肪含量、腰臀比诊断VFO均有较高准确性(ROC曲线下面积为0.718~0.837),其中腰围判断VFO的诊断效率最好.(2)判断VFO的最佳切点及其敏感性和特异性在男性和女性分别是:腰围为89.5、85.5 cm;体重指数为25、26 kg/m2;腰臀比为0.97、0.95;全身脂肪含量为29%、38%;全身脂肪重量为18.6、20.4 kg;腹内脂肪厚度为38.5、34.7 mm.结论 简易体脂参数、体脂仪、超声可用于临床定量评估内脏脂肪变化.在确定腰围的前提下,结合超声或体脂仪参数可进一步判断腹型肥胖的类型.  相似文献   

13.
INTRODUCTION Obesity increases the risk of type2diabetes,hypertension,dyslipidemia,atherosclerosis,several types of cancer and many other diseases.These diseases have been shown more closely related to the accumulation of visceral(intra-abdominal)adipose …  相似文献   

14.
目的研究2型糖尿病患者简易体脂参数与腹壁皮下(SA)及腹腔内脂肪含量(VA)的关系,并且用简易体脂参数来建立预测SA及VA的方程。方法应用计算机断层扫描对91例男性2型糖尿病患者在腰椎4-5间隙水平进行SA及VA的测量,同时测量其体重(W)、身高(H)、体重指数(BMI)、腰围(WC)、臀围(HC)以及腰臀比(WHR)。随机抽取80%的病例(77例)通过多元逐步回归分析,分别以SA及VA为因变量,W、BMI、WC以及WHR为自变量.建立回归方程,用剩余的20%受试者(14例)对回归方程进行回代验证。结果在男性2型糖尿病患者,预测SA的回归方程中包含了BMI,预测VA的回归方程中包含了WC和BMI;在回代验证中,SA的预测值与测量值之间的平均差异为+4.34%.VA的预测值与测量值之间的平均差异为+2.06%,预测值与测量值之间的吻合程度较好。结论男性2型糖尿病患者的SA及VA可以通过简易体脂参数来预测。  相似文献   

15.
目的:探讨简易体脂参数与腹壁皮下(SA)及腹腔内脂肪含量(VA)的关系,并且用年龄、简易体脂参数来建立预测SA及VA的方程。方法:应用计算机断层扫描对309例志愿受试者(男88例,女221例)在腰椎4、5间隙水平进行SA及VA的测量,同时测量其体重(W)、身高(H)、体重指数(BMI)、腰围(WC)、腹围(AC)、臀围(HC)以及腰臀比(WHR)。随机抽取80%的受试者(259例,其中男性78例,女性181例)通过多元逐步回归分析,分别以SA及VA为因变量,年龄、W、H、BMI、WC、AC、HC以及WHR为自变量,建立回归方程,用剩余的20%受试者(50例,其中男性10例,女性40例)对回归方程进行回代验证。结果:在男性,预测SA和VA的回归方程中均包含了WC和年龄;在女性,预测SA的回归方程中包含了AC和BMI,预测VA的回归方程中包含了WHR、W和年龄。在回代验证中,VA的预测值与测量值之间的平均差异在男、女性分别为-7.83%和-6.94%;SA的预测值与测量值之间的平均差异在男、女性分别为8.01%和O.69%,预测值与测量值之间的吻合程度较好。结论:SA及VA可以通过年龄与简易体脂参数来预测。  相似文献   

16.
Background Obesity is a risk factor for multiple chronic diseases. Aim To determine the relationship between overall or abdominal obesity and various metabolic abnormalities. Methods The medical records of participants undergoing examination from January 2000 to December 2002 were analysed. Body mass index (BMI; kg/m2) for overall obesity and waist circumference (WC; cm) indicating abdominal obesity were measured. Four groups were studied: (1) BMI<27kg/m2, WC: female<80cm or male<90cm; (2) BMI≥ 27kg/m2, WC: female<80cm or male< 90cm; (3) BMI<27kg/m2, WC: female ≥ 80cm or male = 90cm; (4) BMI≥ 27kg/m2, WC: female ≥ 80cm or male≥ 90cm. Results There were 1,342 (44%) females and 1,711 males aged 20–87 years. The prevalence of overall obesity was 20.4% and abdominal obesity was 48%. Obese subjects had more metabolic abnormalities than non-obese in terms of risk of hypertension, hyperglycaemia, hypercholesterolaemia, hypertriglyceridaemia, high level of LDL, low level of HDL, high ratio of TC/HDL, hyperuricaemia and fatty liver. Conclusions As overall and abdominal obesity may predict clustering of metabolic abnormalities we suggest that BMI and WC are convenient methods for assessing metabolic abnormalities in primary healthcare settings.  相似文献   

17.
Generalised obesity and central obesity are risk factors for Type II diabetes mellitus and cardiovascular diseases. Waist circumference (WC) has been suggested as a single screening tool for identification of overweight or obese subjects in lieu of the body mass index (BMI) for weight management in public health program. Currently, the recommended waist circumference cut-off points of > or = 94cm for men and > or =80cm for women (waist action level 1) and > or = 102cm for men and > or = 88cm for women (waist action level 2) used for identification of overweight and obesity are based on studies in Caucasian populations. The objective of this study was to assess the sensitivity and specificity of the recommended waist action levels, and to determine optimal WC cut-off points for identification of overweight or obesity with central fat distribution based on BMI for Malaysian adults. Data from 32,773 subjects (14,982 men and 17,791 women) aged 18 and above who participated in the Third National Health Morbidity Survey in 2006 were analysed. Sensitivity and specificity of WC at waist action level 1 were 48.3% and 97.5% for men; and 84.2% and 80.6% for women when compared to the cut-off points based on BMI > or = 25kg/m2. At waist action level 2, sensitivity and specificity were 52.4% and 98.0% for men, and 79.2% and 85.4% for women when compared with the cut-off points based on BMI (> or = 30 kg/m2). Receiver operating characteristic analyses showed that the appropriatescreening cut-off points for WC to identify subjects with overweight (> or = 25kg/m2) was 86.0cm (sensitivity=83.6%, specificity=82.5%) for men, and 79.1cm (sensitivity=85.0%, specificity=79.5%) for women. Waist circumference cut-off points to identify obese subjects (BMI > or = 30 kg/m2) was 93.2cm (sensitivity=86.5%, specificity=85.7%) for men and 85.2cm (sensitivity=77.9%, specificity=78.0%) for women. Our findings demonstrated that the current recommended waist circumference cut-off points have low sensitivity for identification of overweight and obesity in men. We suggest that these newly identified cut-off points be considered.  相似文献   

18.
Chen L  Xiang KS  Jia WP  Lu JX  Bao YQ  Lu HJ 《中华医学杂志》2005,85(21):1456-1459
目的探讨血清脂联素浓度与体脂分布及组织胰岛素敏感性的关系。方法对44例上海地区正常糖耐量中国人,其中正常体重组(体重指数<25kg/m2)12例、超重组(25kg/m2≤体重指数<30kg/m2)19例及肥胖组(体重指数≥30kg/m2)13例进行扩展高胰岛素正葡萄糖钳夹试验,以钳夹稳态期的胰岛素介导的葡萄糖利用率(Rd)来判定周围组织的胰岛素敏感性。同时测定总体脂[体重指数、体脂百分比(FAT%)、身体脂肪块重量(FM)]、局部体脂[腰围、臀围、腰臀比、腹部皮下脂肪面积(SA)、腹腔内脂肪面积(VA)和股部皮下脂肪面积(FA)],并应用放射免疫法测定空腹血清脂联素浓度。结果(1)在校正年龄、性别后,超重组及肥胖组的血清脂联素浓度(8.7mg/L±4.8mg/L及6.7mg/L±0.8mg/L)均低于正常体重组(15.7mg/L±1.8mg/L,均P<0.01);(2)血清脂联素浓度与体重指数、腰围、腰臀比、FAT%、FM、VA均呈负相关,但与腰围、VA的相关性最强(r值分别为-0.46和-0.53,均P<0.01);(3)血清脂联素浓度与Rd(r=0.52,P<0.01)及糖原合成率(r=0.36,P<0.05)呈正相关,而与游离脂肪酸浓度呈负相关(r=-0.41,P<0.05);(4)多元逐步回归分析表明,血清脂联素浓度是除性别、体重指数、腰臀比或VA、SA以外,对Rd的独立影响因素,其贡献值分别为3.52%和4.84%(均P<0.05)。结论(1)血清脂联素浓度降低与总体脂增加,尤其是腹腔内体脂增加关系最为密切;(2)血清脂联素浓度是独立于体脂因素之外的影响胰岛素敏感性的因素之一。  相似文献   

19.
目的:通过比较人体测量学方法与定量CT (QCT )方法,探讨人体测量方法与QCT测量腹内脂肪的相关性及预测误差。方法测量568名中国成人(男234人,女334人)身高、体质量、腰围、臀围,并进行腰椎CT 扫描。采用Mindways QCT软件的体质成分测量功能定量测量腹部脂肪分布,测得T12、L1、L2、L3、L4、L5椎体下缘水平及脐层面的腹内脂肪面积(VFA)和总脂肪面积(TFA),计算出皮下脂肪面积(SFA)、总腹内脂肪体积(TVFV)、总皮下脂肪体积(TSFV)、总脂肪体积。采用线性回归分析体质量指数(BMI)、腰围、臀围和腰臀比同VFA的相关性,用标准估计误差(SEE)预测VFA同实际脂肪面积的误差值。结果腰围与不同解剖位置的 VFA相关性均优于臀围、BMI和腰臀比,其相关系数 R2分别为0.48~0.64(男)、0.53~0.66(女),P<0.01。腰围预测VFA同实际脂肪面积的 SEE分别为25.36~31.57 cm2(男),23.64~25.31 cm2(女)。达均值为23.13%~27.78%(男),25.44%~36.03%(女)。结论人体测量学参数预测VFA的 SEE较显著,而QCT可以更精确地测量VFA ,具有临床应用潜力。  相似文献   

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