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1.
良性前列腺增生术后真性压力性尿失禁发生率为2.6%,为泌尿外科临床的一道难题。目前治疗方法主要有经尿道腔内注射、球部尿道悬吊和人工括约肌安置术,疗效均不够满意,后两种方法采用人工材料,手术并发症多,尿道受压坏死和发生感染率分别达5%和3%。2003年2月至2007年4月,我科采用了球部尿道-膀胱出口吻合功能性尿道重建术,治疗前列腺术后真性压力性尿失禁患者20例,疗效较满意,现将护理体会报告如下。  相似文献   

2.
目的探讨膀胱尿道软镜联合绿激光治疗前列腺增生术后后尿道狭窄与闭锁的临床疗效。方法使用绿激光对经膀胱尿道软镜检查明确诊断的前列腺增生术后后尿道狭窄或闭锁的患者19例,行经尿道狭窄段或闭锁段绿激光汽化术。其中前列腺摘除术后后尿道狭窄10例,经尿道前列腺电切手术后9例。术后留置尿管1周~1个月。结果 19例患者手术均一次性成功,手术时间25~90 min,平均67 min,随访6~18个月,16例患者一次治愈或术后仅需2~3次尿道扩张后治愈,其余3例患者经多次定期尿道扩张后4~8个月内治愈。无尿失禁患者出现。结论膀胱尿道软镜联合绿激光治疗前列腺增生术后后尿道狭窄与闭锁安全有效。  相似文献   

3.
目的观察用Madigan手术治疗良性前列腺增生的疗效,评价分析Madigan术式切除前列腺的临床意义。方法用耻骨后保留尿道前列腺切除术治疗良性前列腺增生78例。探查并处理膀胱病变后,前列腺包膜逐一钳夹、切开、结扎,预留包膜对合线。在无血情况下游离腺体,剥离出尿道,切除前列腺腺体,将预留的包膜对合结扎,膀胱造瘘。结果所有患者均顺利完成手术,术中出血少。全部病例排尿通畅,无膀胱颈狭窄、尿道狭窄和尿失禁,未见远期并发症。结论耻骨后保留尿道前列腺切除术保留了尿道的完整性及连续性,减少了术后的并发症,是基层医院开展良性前列腺增生治疗的良好术式。  相似文献   

4.
目的 探讨经耻骨后 会阴联合切口行根治性前列腺切除术后尿道重建新方法的优缺点。方法 对 6例前列腺癌患者采用经耻骨后 会阴联合切口行前列腺癌根治性切除及后尿道重建术式 ,术中常规行耻骨后前列腺根治性切除后 ,另经会阴部切口游离 4~ 6cm残余尿道 ,将其拉入盆腔与膀胱颈部吻合。结果 术后留置尿管 14~2 8天 ,平均 2 1 6天。随访 2~ 17个月 ,平均 7 3月 ,5例排尿通畅 ,控尿能力良好 ,无尿失禁发生。1例术后 1个月内会阴部伤口感染 ,拔除尿管后排尿困难 ,现仍定期行尿道扩张中。结论 经耻骨后 会阴联合切口行根治性前列腺切除术及后尿道重建的新方法可使吻合口处显露良好 ,吻合张力低 ,粘膜对合整齐 ,可明显降低术后尿失禁及尿道狭窄发生率。但其远期疗效尚需大量病例的长期随访观察。  相似文献   

5.
目的 提高高危良性前列腺增生患者围手术期的治疗及护理水平,降低手术风险及死亡率.方法 采用经尿道前列腺电切术治疗高危良性前列腺增生患者24例.结果 24例均顺利完成手术,无手术死亡.术后发生尿潴留1例,经定期尿道扩张及膀胱功能锻炼2周后恢复自行排尿.尿失禁2例,经提肛训练1个月后,症状逐渐消失.结论 充分的术前准备及合理围手术期处理及护理是降低高危良性前列腺增生患者手术风险及死亡率的关键.  相似文献   

6.
目的 观察用Madigan手术治疗良性前列腺增生的疗效,评价分析Madigan术式切除前列腺的临床意义。方法 用耻骨后保留尿道前列腺切除术治疗良性前列腺增生78例。探查并处理膀胱痛变后,前列腺包膜逐一钳夹、切开、结扎,预留包膜对合线。在无血情况下游离腺体,剥离出尿道,切除前列腺腺体,将预留的包膜对合结扎,膀胱造瘘。结果 所有患者均顺利完成手术,术中出血少。全部病例排尿通畅,无膀胱颈狭窄、尿道狭窄和尿失禁,未见远期并发症。结论 耻骨后保留尿道前列腺切除术保留了尿道的完整性及连续性,减少了术后的并发症,是基层医院开展良性前列腺增生治疗的良好术式。  相似文献   

7.
目的探讨耻骨上经膀胱前列腺摘除术治疗良性前列腺增生患者的临床经验。方法对50例良性前列腺增生患者行耻骨上经膀胱前列腺摘除术治疗,观察手术时间、术中出血量、近期疗效及并发症等。结果 45例切口均一期愈合,5例切口延迟愈合。47例术后排尿通畅,无尿失禁及尿道狭窄等并发症,未发生继发性出血。3例术后发生暂时性尿失禁,经训练后排尿正常。结论耻骨上经膀胱前列腺摘除术治疗良性前列腺增生患者手术时间短,术中出血量及并发症少,疗效满意。  相似文献   

8.
良性前列腺增生术后排尿困难原因分析(附40例报告)   总被引:1,自引:0,他引:1  
目的探讨良性前列腺增生术后部分患者排尿困难症状无改善的原因。方法对40例良性前列腺增生术后出现排尿困难的患者行尿流动力学检查,IPSS评分,排尿性膀胱尿道造影及膀胱尿道镜检。结果尿道狭窄15例(开放手术5例、经尿道电切10例);膀胱颈挛缩10例(开放手术5例,经尿道电切5例);腺体残留7例(开放手术4例,经尿道电切3例);膀胱功能异常8例(开放手术1例,经尿道电切术后7例)。结论尿道狭窄,膀胱颈挛缩,腺体残留,膀胱功能异常是良性前列腺增生术后排尿困难的常见原因。  相似文献   

9.
目的 探讨耻骨后保留尿道起始部前列腺摘除术治疗良性前列腺增生的效果.方法 采用经耻骨后保留尿道起始部前列腺摘除术治疗良性前列腺增生56例.年龄61~92岁,平均73.5岁.急性尿潴留38例,合并膀胱结石13例,急性肾衰7例,中后叶明显突入膀胱19例.结果 56例手术顺利.手术时间50~90min.术中出血100~600mL.术后持续膀胱冲洗12~24h.10~12d拔尿管,均排尿通畅,术后B超测残余尿量小于40 mL.随访3~18个月无1例排尿困难、尿失禁发生.结论 耻骨后保留尿道起始部前列腺摘除术保留了膀胱颈的完整性,不损伤尿道外括约肌,无需作膀胱造瘘,膀胱冲洗时间短,术后并发症少,住院时间短,值得推广.  相似文献   

10.
目的 探讨新鲜后尿道损伤早期端端吻合术的处理.方法 11例后尿道损伤病人,在积极抗休克的同时,采取急诊尿道端端吻合术、膀胱造瘘和插入双腔气囊导尿管方法,平均置管八周.结果 好7例 较好3例,经尿道扩张2次排尿通畅 差1例,经二次手术治愈.11例病人随诊1~5年,排尿通畅,未发现阳萎和尿失禁现象.结论 早期行尿道重建术,断端吻合准确,术后尿道狭窄机会少,即使发生狭窄其长度也较短,且不增加术后阳萎和尿失禁的发生率.  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

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