重组牛碱性成纤维细胞生长因子滴眼液在全麻手术患者眼睛保护中的应用

目的 观察重组牛碱性成纤维细胞生长因子滴眼液(贝复舒滴眼液)及四环素眼膏对全麻手术患者眼睛的保护作用.方法 选择2013年6~12月在我院外科住院手术治疗的全麻患者60例,再按住院号单双随机分为两组.对照组30例,全麻后常规用四环素眼膏涂眼;观察组30例,全麻后应用贝复舒滴眼液进行眼睛保护.比较两组患者眼睛的使用效果.结果 观察组患者术后共出现并发症4例,发生率为13.3%,其中暂时性视力模糊者3例,出现异物感1例,未见暴露性角膜炎及结膜炎发生.对照组术后共出现并发症17例,发生率为56.7%,其中暂时性视力模糊者15例,暴露性角膜炎症状3例,出现或合并异物感7例;3例暴露性角膜炎患者中有2例合并结膜炎,应用贝复舒及复方硫酸新霉素滴眼液治疗2~4d后症状消失.两组患者的并发症发生率比较差异有统计学意义(P<0.05).结论 全麻手术患者术前使用贝复舒滴眼液进行眼睛保护,可减少术后暴露性角膜炎等常见眼科疾病的发生,为全麻手术提供一种效果好、便捷、安全可靠的新型眼睛保护方法.     

术后暴露性角膜炎6例临床分析

暴露性角膜炎 (又名兔眼性角膜炎 ) ,凡眼睑不能遮盖角膜的一切疾病或外因都可引起暴露性角膜炎[1] 。我院 2 0 0 1年 1～ 7月发生 6例术后暴露性角膜炎 ,通过及时治疗、护理全部治愈 ,报告如下。1　临床资料1 1　一般资料 :见表 1。表 1　 6例术后暴露性角膜炎的一般资料例序 1 2 3 4 5 6年龄 (岁 ) 1 946 32 392 752性别男男男男女女手术名称内窥镜下右上颌窦根治术左乳突根治术+鼓室成形术甲状舌骨囊肿切除术右下颌骨囊肿切除术腮腺切除术胆囊切除 +胆总管探查术麻醉方法局麻 局麻 +强化麻醉 全麻全麻全麻全麻手术时间 (ｈ) 1 .5 3 .5 1 …     

我院全麻术暴露性角膜炎防治与护理104例体会

目的 探讨暴露性角膜炎的防治与护理.方法 观察组54例用鱼腥草热敏凝胶滴眼液术前术后滴眼,并施行专科康复护理和心理护理;对照组50例用抗菌消炎眼药水滴眼和常规防患护理,术后3d观察临床症状,并用荧光素染色.结果 观察组阳性检出率明显低于对照组(P＜0.01).结论 用热敏凝胶点眼并施行专业护理能有效防治全麻术暴露性角膜炎.     

医用水凝胶护眼贴预防全麻术后暴露性角膜炎疗效观察

目的探讨医用水凝胶护眼贴预防全麻术后暴露性角膜炎的临床效果。方法将120例全麻患者随机分为试验组和对照组,每组各60例。试验组术中使用医用水凝胶护眼贴,对照组术中使用金霉素眼膏联合无菌薄膜粘贴眼睛预防术后角膜炎的发生。术后分别观察比较两组患者结膜红肿、黏滞感、异物感、视物模糊等不适症状的发生率。结果两种眼部保护方式术后不适感比较差异有统计学意义（P〈0.05,P〈0.01）。结论采取医用水凝胶护眼贴能有效预防全麻术后暴露性角膜炎的发生,降低患者眼部不适率的发生,具有较好的临床应用价值。     

复方洗必泰滴眼液治疗真菌性角膜炎的临床研究

目的　探讨复方洗必泰滴眼液对真菌性角膜炎的治疗作用。方法　将真菌性角膜炎患者 65例68眼分为两组 ,每组 34眼 ,实验组用复方洗必泰滴眼液点眼。对照组用 0 .3%二性霉素B溶液滴眼治疗 ,并且回顾研究以前接治的未采用以上两法治疗的 30例病人的情况。疗效观察比较 ,所获数据经 χ2 检验。结果　实验组有效率 82 .35% ,阳性对照组有效率 67.65% ,卡方检验 ,P <0 .0 5,有统计学差异 ;回顾以前病人有效率 4 0 % ,与实验组比较 ,P <0 .0 0 5,差异显著。结论　复方洗必泰滴眼液可以作为临床抗真菌性角膜炎的一线局部用药 ,其疗效明显高于二性霉素B及其它传统药物治疗效果。     

全麻下头面部手术患者的眼部护理

目的观察全麻下头面部手术患者眼睛的护理效果。方法将172例患者随机分为对照组、试验组,各86例,对照组仅用红霉素眼膏涂抹患者双眼,试验组用红霉素眼膏联合3L手术粘贴巾覆盖患者双眼,观察术后两组患者眼睛有无结膜炎、角膜炎等症状。结果试验组出现结膜炎、角膜炎等症状明显少于对照组（P〈0.05）。结论全麻下头面部手术患者眼睛护理能减少术后结膜炎、角膜炎等症状。     

全麻复合硬膜外阻滞在上腹部手术中的应用

目的　观察全麻复合硬膜外阻滞在上腹部手术中的应用效果。方法　选 2 0例择期胃癌根治术或胆道探查术患者 ,随机分为全麻组 (对照组 )和全麻复合硬膜外组 (观察组 ) ,每组 10例。两组病人全麻诱导方法相同 ,观察组病人于全麻前行T8-9或T9-10 椎间隙硬膜外穿刺置管 ,局麻药用 2 %利多卡因 ,麻醉平面控制在T4以下 ,术中维持每 6 0min追加局麻药 1次 ,并吸入笑气和异氟醚。全麻组术中间断静注芬太尼和维库溴铵 ,并吸入笑气和异氟醚维持麻醉。对照组MAC控制在 1 3左右 ,观察组MAC控制在 0 . 8左右即可。结果　观察组芬太尼、维库溴铵用量及术中异氟醚吸入浓度明显低于对照组 (P <0 . 0 5 ) ,笑气吸入浓度无显著差异。两组病人术中均无知晓 ,对照组 2例病人拔管后躁动 ,而观察组无 1例发生。观察组术后止痛药物的用量明显少于对照组。结论　全麻复合硬膜外麻醉是一种值得推广的麻醉方法。     

Acyclovir for the treatment and prevention of recurrent infectious herpes simplex keratitis

目的　观察无环鸟苷对HSV 1角膜炎的治疗和预防复发作用。方法　选用 1 0 5例HSV角膜炎病人 ,将病人按临床表现分为 4组 ,即上皮型、基质型、坏死型及HSV角膜炎行角膜移植及结膜瓣遮盖术 ,并对 4组病人选用全身 +局部无环鸟苷治疗。愈后将上皮质型和基质型患者随机分为2组 ,抗复发治疗组和对照组。治疗组给予口服预防量无环鸟苷 3 0 0mg/d ,持续一年。对照组未给予任何药物。结果　上皮型经口服及局部点眼后 96%痊愈。基质型给予口服加局部无环鸟苷点眼 ,同时给予激素滴眼治愈率为 1 0 0 %。坏死型经 1 0 0 0mg/d无环鸟苷静脉应用 ,治愈率达 3 3 % ,余穿孔行结膜瓣遮盖及角膜移植术 ,术后静脉应用无环鸟苷 2周尽快控制病情 ,角膜植片及结膜与伤口愈合。上皮质型和基质型的角膜炎治愈后持续应用无环鸟苷口服 3 0 0mg/d ,随访 1年 ,治疗组有 5例复发 ,对照组有 1 4例复发 ,两组比较有显著的统计学差 (P <0 0 1 )。结论　无环鸟苷局部 +全身治疗对HSV角膜炎有较好的治疗作用 ,低剂量长期口服对控制复发有良好的作用。随访期间未见全身及局部副作用     

防毒灵汤为主治疗复发性单纯疱疹性角膜炎40例

目的 :观察防毒灵汤为主治疗复发性单纯疱疹性角膜炎炎症期的疗效。方法 :70例 (78只眼 )单纯疱疹性角膜炎患者随机分为治疗组和对照组 ,治疗组用防毒灵汤加减内服及防毒滴眼液滴眼 ,对照组用无环鸟苷滴眼液。结果 :对于树枝状角膜炎 ,治疗组和对照组的有效率分别为 10 0 % ,88.2 4 % ;治疗组和对照组治愈时间分别为 (7.5 8± 1.6 6 )d ,(10 .11± 4 .5 1)d ,两组比较有显著性差异 (t =2 .32 ,P <0 .0 5 )。对于地图状角膜炎 ,治疗组和对照组有效率分别为94 .4 4% ,83.33% ;治疗组和对照组治愈时间分别为 (18.90± 3.2 1)d ,(2 5 .30± 7.2 8)d ,两组比较有显著性差异 (t =2 .4 0 ,P <0 .0 5 )。两组的视力治疗后比治疗前都有明显提高。结论 :防毒灵汤为主对急性期复发性单纯疱疹性角膜炎炎症期疗效优于无环鸟苷滴眼液。     

手术治疗儿童先天性上睑下垂63例

目的：探讨儿童先天性上睑下垂的手术方式、临床效果及术后并发症的处理.方法：对我院住院的63例（89只眼）先天性上睑下垂患者行手术治疗,患者年龄3～12岁,平均7.5岁.按上睑下垂的严重程度分为A、B两组,分别行额肌瓣悬吊术（A组）与提上睑肌缩短术（B组）,术后追踪3个月至4年,观察术后上睑下垂矫正效果,上睑弧度形态及内翻倒睫、结膜脱垂、暴露性角膜炎等并发症.结果：A组38只眼中,欠矫2只眼,暴露性角膜炎2只眼;B组51只眼中,欠矫3只眼,过矫3只眼,结膜脱垂2只眼;结膜脱垂病人其中1只眼经加压包扎及使用激素眼药水点眼后结膜脱垂消失,另1只眼行从穹窿部穿越皮肤的褥式缝合使结膜回位;暴露角膜炎患者经保护角膜、抗生素点眼等治疗后症状完全缓解;两组患者术后初期均有不同程度的闭睑不全,观察3个月至4年,A组患者中有20只眼能闭睑完全,B组患者中有48只眼能闭睑完全;绝大多数患者上睑弧度自然,重睑成形优美,上睑下垂无复发,效果良好.结论：提上睑肌缩短术和额肌瓣悬吊术对于儿童先天性上睑下垂均为安全有效的手术方式,手术并发症发生率低,疗效确切.     

Acupuncture Treatment of Vomiting

CASE HISTORY A female patient, 46 years old, head of the foreign affairs department of a certain university in Beijing, paid her first visit on October 9, 2006, with the chief complaint of vomiting for one month. She got vomiting after meals in early September. Before that, she had discomfortable sensation in the stomach due to angry with others, but she didn't pay much attention. Later, it developed into vomiting after eating. After the vomiting, the discomfort would be relieved, but with slight hypodynamia. She was once diagnosed as having 'neurogenic vomiting'. Having taken some western and Chinese drugs, the above symptoms were a little bit improved, but she would have nausea upon eating and with regurgitation. Because of the fear for vomiting, she did not dare to have food intake, with body weight reduction of 6 kilos in one month.     

Qiu Baoguo''''s Experience in Treating Consumptive Syndromes after Radio-Chemotherapies

Radiotherapy and chemotherapy are the important modern medical therapies for malignant tumors,yet they can also bring about serious local and systemic toxic side reactions so to decrease the patient;'s life quality,manifested by a series of consumptive symptoms.Having engaged in the combined work of Chinese and western medicine for nearly 50 years,the research fellow Qiu Baoguo in Henan Provincial Academy of TCM has developed his unique views on the TCM study of consumptive syndromes.The author of this essay had once the fortune tO follow Dr.Qiu in clinic,and specially would like to introduce in the following Dr.Qiu's experience in treating consumptive syndromes after radio-chemotherapies for patients with malignant tumor.     

Insomnia Due to Deficiency of Both the Heart and Spleen Treated by Acupuncture-Moxibustion and Chinese Tuina

OBJECTIVE: To observe therapeutic effects of the comprehensive therapy of acupuncture-moxibustion and Chinese Tuina for treatment of insomnia due to deficiency of both the heart and spleen. METHODS: 92 cases were divided randomly into the treatment group (treated by acupuncture-moxibustion and Chinese Tuina) and the control group (treated by acupuncture-moxibustion). RESULTS: The therapeutic effect of the treatment group was obviously superior to that of the control group (the CHI2 test showed P < 0.01). CONCLUSIONS: The comprehensive therapy of acupuncture-moxibustion and Chinese Tuina can give marked therapeutic effects for treatment of insomnia due to deficiency of both the heart and spleen.     

Analysis of CK-19,PDX-1,Nestin,Ngn3 in different donor islet purity in rats

Objective: To investigate if there are the CK-19, PDX-1, Nestin, Ngn3 positive cells in the donor islets of different purity in rats. Methods: Thirty male adult SD rats were randomly divided into 3 groups. Islets were isolated using digestion by ductal injection of collagenase. Group Ⅰ (n=10): Separating cell preparations were not purified, Group Ⅱ(n=10): Islet sediment was purified with 25% Ficoll400 ,Group Ⅲ (n=10): Islet sediment was purified with 25% and 11% Ficoll-400. The levels of protein of CK-19, PDX-1, Nestin and Ngn3 were detected by immunohistochemistry and the mRNA of CK-19, PDX-1, Nestin, Ngn3 was amplified by RT-PCR. Results: After two different purification methods applied, three islet preparations of different purities were obtained. The difference of islet purity was significant among various groups (P＜0.05). Compared with group Ⅱ and group Ⅲ,the protein and mRNA of CK-19, PDX-1, Nestin,Ngn3 were both higher in group Ⅰ; group Ⅲ was poorly expressed. Conclusions: The three different islet purity donor islet have different CK-19, PDX-1, Nestin, Ngn3 positive cells within them, indicating that there are some islet stem cells in the purified donor islet.     

A preliminary screening study on the associated proteins in human psoriasis vulgaris by serum proteomics technologies

Objective：To investigate the optimum screening conditions of associated proteins in human psoriasis vulgaris by serum proteomics technique, and to screen the different expression proteins related with psoriasis vulgaris. Methods：Serum samples of peripheral blood were collected from newly diagnosed psoriasis vulgaris patients in the clinic, and 20 matched healthy persons. Serum albumin IgG was removed by filtering with ProteoExtract Albumin/IgG. After comparative proteomics analysis the different protein spots were identified using 2-DE and MS. Results ：Electrophoresis figures with high resolution and reproducibility were obtained. Three different expression proteins were found only in the serum from psoriasis vulgaris patients, while nine other different proteins expressing from healthy volunteers. Conclusion：The protein expression was different in the serum between the psoriasis vulgaris patients and healthy volunteers. It was hoped that we could find the biomarkers related to psoriasis vulgaris by using proteomics.     

A CASE OF HUGE GASTRIC DISOPYROBEZOAR

PYTOBEZOARS are common bezoars in gastrontestinal tract, commonly seen in stomach and mall intestine,1but huge disopyrobezoars are     

Acupuncture Treatment of Chest Bi Syndrome

CASE HISTORY A male,a retired officer of 61 years old,paid his first visit on May 12,2006.The patient stated that 2 weeks before he suddenly got paroxysmal precordial choking pain,with irregular attacks.Each attack would last several seconds to several minutes.The attack was accompanied with heavy oppressed sensation in the precordial region,palpitation,lassitude,and in severe cases,sweating,which was once diagnosed by a hospital as'coronary heart disease'.Recalling the case history,the patient said that several days before he got angry with others because of some affairs in work,and he was not so used to the life pattern since he had just retired from his busy working post.At usual times,he was quick tempered and peevish.In recent days,he had poor appetite,and loose stool.     

Instructions to Contributors

The English edition of Chinese Journal of Integrative Medicine is edited and published by the Chinese Journal of Integrated Traditional and Western Medicine Press.Original scientific papers of advanced clinical and experimental medicine in the field of complementary/alternative medicine or integrative medicine are expected.