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1.
作者采用超短波加红外线治疗贝尔麻痹 ,并与单纯音频电治疗的效果进行比较。现报告如下。1 对象和方法1.1 对象 将 1998年 1月~ 2 0 0 1年6月来我院门诊求治、经药物治疗无明显疗效的 12 7例患者随机分成 2组。超短波加红外线组 :6 8例 ,其中男 36例 ,女 32例 ;平均年龄 4 7.4± 6 .9岁 ,左侧 2 6例 ,右侧 4 2例。单纯音频电组 :5 9例 ,其中男 35例 ,女 2 4例 ;平均年龄 4 6 .9± 7.4岁 ,左侧 2 2例 ,右侧 37例。病程均为 2~ 15天。1.2 方法 单纯音频电组 :采用上海产YL - 3型音频电疗机 ,频率 2 0 0 0Hz ,电极 1.5cm× 5cm外包 3… 相似文献
2.
目的 :探讨鼻声反射和鼻阻力对测定少年儿童鼻功能的意义。方法 :测试 16 8例 ,男女各半。按年龄分为 3组 ,4~ 6岁 4 6例 ,9~ 10岁 6 0例 ,13~ 14岁 6 2例。鼻塞多涕多嚏和感冒者 ,以及鼻甲肥大 ,中隔明显偏曲 ,鼻黏膜充血伴脓涕者排除。用丹麦Oticom公司提供的RhinoMetrics鼻功能检查仪 ,在学校内安静、没有噪声 ,维持常温 (18~ 2 5 )℃的教室测定。每例测 3次 ,鼻声反射测鼻腔 2个部位即下鼻甲前端(MCA1) ,下鼻甲中段即中鼻甲前端 (MCA2 )的截面积 (CSA )和与前鼻孔的距离 (MCA距 ) ,以及 0~ 5cm容积 ,取均值。每组计算均值和标准差 ,计算 90 %可信区限。结果 :鼻声反射MCA1距 (cm) ,MCA1(cm3) ,MCA2距 (cm) ,MCA2 (cm3) ,0~ 5cm容积 90 %可信区间分别是第 1组 :0 .39± 1.5 4,0 .31± 0 .5 5 ,2 .2 0± 2 .2 0 ,0 .5 5± 1.14 ,4 .2 5± 7.0 4cm3;第 2组 :0 .39± 2 .2 0 ,0 .2 4± 0 .6 5 ,2 .2 0± 3.85 ,0 .2 6± 1.17,1.15± 5 .5 3cm3;第 3组 :0 .77± 2 .2 0 ,0 .4 1± 0 .80 ,2 .2 0± 2 .7,0 .4 4± 1.2 4 ,2 .6 2± 8.4 4cm3。鼻阻力呼气流量 (cm3/s) ,90 %可信限 ,吸气流量 (cm3/s) ,90 %可信限 (kPa ,s/L)分别是第 1组 :16 8.2± 2 1.4 ,14 0 .5± 2 0 5 .3,14 6 .4± 2 0 .8,113.5 相似文献
3.
椎动脉的解剖学研究及其临床意义 总被引:9,自引:0,他引:9
目的为椎动脉的重建术提供解剖学依据。方法在 2 2具 4 4侧经防腐处理的成人尸体标本上 ,观察椎动脉颅外部各段的走行、分支情况 ,测量各段起点的外径、长度。结果椎动脉第 1段起点的外径左侧为 4 .35± 0 .78mm ,右侧为 3.97± 0 .5 6mm ,长度左侧为 4 0 .1± 5 .8mm ,右侧为 39.6± 9.3;第 2段起点外径左侧为 3.5 6± 0 .6 7mm ,右侧为 3.0 4± 0 .82mm ,长度左侧为 5 9.8± 7.3mm ,右侧为 6 0 .2±6 .9mm ;第 3段起点外径左侧为 3.0 3± 0 .4 8mm ,右侧为 2 .98± 0 .75mm ,长度左侧为 38.7± 2 .5mm ,右侧为 39.2± 3.1mm。结论椎动脉颅外部各段测量结果对椎动脉重建术有重要参考价值 相似文献
4.
风湿性二尖瓣狭窄伴心房颤动患者经皮穿刺二尖瓣球囊成形术治疗 总被引:1,自引:0,他引:1
目的 :为研究二尖瓣狭窄伴心房颤动患者经皮穿刺二尖瓣球囊成形术治疗的疗效和安全性。方法 :对 330例病人施行PBMV。男 1 0 4例 ,女 2 2 6例 ,年龄 1 5~ 86岁 ,平均 (40 .3± 1 0 .2 )岁。 2 1 2例为窦性心律 (窦性心律组 )。 1 1 8例为二尖瓣狭窄心房颤动 (心房颤动组 ) :心房颤动病程 1~ 1 2 0 (1 6 .1± 1 8.3)月。二尖瓣狭窄心房颤动病人术后行复律治疗。结果 :330例病人中 32 7例完成手术并达到扩瓣终点 (99.1 % )。PBMV成功者 ,左房平均压从 (2 5 .4± 9.3)mmHg下降到 (1 0 .1± 3 .8)mmHg,肺动脉平均压从 (41 .7± 1 7.4)mmHg下降到 (2 5 .9± 1 3 .2 )mmHg。二尖瓣口面积从 (0 .95± 0 .2 7)cm2 增加到 (1 .82± 0 .2 4 )cm2 ,左房前后径从 (4.94± 0 .61 )cm缩短到 (4.2 8± 0 .53)cm。窦性心律组与心房颤动组PBMV成功率无明显差异 (99.5 %VS98 3 % ,P >0 .0 5)。心房颤动组瓣口面积增加 (0 .77± 0 .2 2 )cm2 ,略小于窦性心律组 (0 .89± 0 .2 4 )cm2 ,P <0 .0 5 ;左房前后径缩短 (0 .64± 0 .61 )cm ,较窦性心律组 (0 .71± 0 .50 )cm缩短程度略小 ,P <0 .0 5 ,而且最终左房前后径明显大于窦性心律组 ;左房平均压降低 (1 2 .2± 4 .4)mmHg,其下降程度也小于窦性心律组 (1 6 .9± 4 .8)mmH 相似文献
5.
血细胞分析仪检测网织红细胞三项参数正常值范围调查 总被引:5,自引:0,他引:5
目的 :确定CELL DYN 370 0血细胞分析仪检测网织红细胞三项参数正常值范围。方法 :用CELL DYN 370 0血细胞分析仪 ,对 10 2名正常成年人 (男、女各半 )作网织红百分比 (RET % )、网织红细胞绝对数 (RET # )和未完全成熟网织红细胞分数 (IRF)三项参数正常值范围调查 ,并将所得数据进行统计学分析。结果 :RET % :男性 (2 1~ 39周岁 ) 1.80± 0 .35 ,女性 (2 0~39周岁 ) 1.76± 0 .31,两组差异无显著性 (P >0 .0 5 ) ,合并后 10 2名RET %为 1.78± 0 .37(1.12~ 2 .4 4 ) ;RET # (× 10 9/L) :男性 91.4± 2 8.3(34.8~ 14 8.0 ) ,女性 72 .3± 2 5 .6 (2 1.1~ 12 3.5 ) ,两组差异有显著性 (P <0 .0 1) ;IRF :男性 0 .14± 0 .0 6 (0 .0 2~0 .2 6 ) ,女性 0 .13± 0 .0 5 (0 .0 3~ 0 .2 3) ,两组差异无显著性 (P >0 .0 5 ) ,合并后 10 2名IRF为 0 .14± 0 .0 5 (0 .0 4~ 0 .2 4 )。结论 :网织红细胞三项参数成人正常值范围的测定基本上与文献报道一致 ,但范围随性别、仪器等因素的影响而有差异。因此 ,各实验室应根据具体情况建立正常值参考范围 相似文献
6.
1991年 1月~ 1 999年 1月我院收治支气管哮喘患者 434例 ,将这些患者按年龄不同分成青年组和老年组 ,并对比分析其各临床特点。1 临床资料 所有病例均符合《全国第一届哮喘会议》诊断标准。分为 1 4~ 39岁 1 0 3例 (青年组 ) ;40~ 59岁 1 2 6例 ;≥ 60岁 2 0 5例 (老年组 )。哮喘在老年期起病者 56例 (老年发病组 ) ,占老年组 2 7 3 % ,占总数的1 2 9%。病程 :老年组、老年发病组、青年组分别为 (1 9 5± 1 5 0 )、(5 7± 5 6)和 (9 0± 1 0 2 )年。首次发病年龄 :在 1 4岁以前老年组4 2 % ,青年组 30 1 % ,两者差异显著 (P <0 … 相似文献
7.
为了有效减除早孕女性人流术时的扩宫痛 ,我院2 0 0 2年 1~ 12月对 4 0例行人流术的早孕女性给予小剂量氯胺酮 ,再静注异丙酚维持麻醉 ,起到了良好的镇痛效果 ,现报告如下。1 临床资料1 1 一般资料 :行人流术早孕 4 0例 ,随机等分为两组 :A组 :异丙酚组 (以下同 ) ;平均年龄 2 1 2 5± 1 92(2 0~ 2 5 )岁 ,孕期 5 1 7± 6 3(4 1~ 6 5 )d ;体重 5 1±5 15kg。B组 :氯胺酮异丙酚组 (以下同 ) ;平均年龄2 1 4 2± 1 8(2 0~ 2 6 )岁 ;孕期 5 0± 6 3(4 0~ 6 5 )d ;体重4 9 9± 4 87kg。两组年龄、孕期及体重均无显著性差… 相似文献
8.
目的 :为给通过临床造影术来诊断下肢静脉系统疾病提供参考依据 ;为断肢再植、自体大静脉移植或搭桥以重建血液循环术[1~ 3 ] 提供解剖学基础。方法 :取患有下肢静脉疾病的男性成人X线造影片和正常成人男尸下肢各 31侧 (左右各半 ) ,在股、静脉上取五个位点分别进行外管径测量。结果 :发现在第一、二、三、四、五位点上 ,男尸左侧依次为 9.9871± 0 .3385 (χ±Sχ)mm ,8.1194± 0 .4 0 5 2mm ,8.5 2 4 2± 0 .3812mm ,8.2 2 74± 0 .4 347mm ,8.1932± 0 .384 0mm ;男患左侧分别是 13.5 984± 0 .4 5 2 9mm ,13.95 97± 0 .345 2mm ,13.4 6 77± 0 .3379mm ,13.96 13± 0 .375 0mm ,13.0 74 2± 0 .3933mm ;男尸右侧为 9.4 80 6± 0 .390 3mm ,8.1790± 0 .3889mm ,8.2 935± 0 .3879mm ,7.772 6± 0 .3876mm ,8.0 387± 0 .4 393mm ;男患右侧 14.32 4 2± 0 .4 6 2 9mm ,12 .4 72 9± 0 .2 92 8mm ,14.2 30 6± 0 .4 16 7mm ,13.932 3± 0 .4 6 13mm ,13.796 8± 0 .4 4 5 6mm。经方差分析 ,P值 <0 .0 1。结论 :尸体与病理造影片的股、静脉外径大小有显著性差异 ,下肢静脉造影是临床诊断下肢静脉系统疾病的重要手段[4 ] 。尸体与病理造影的股、静脉管径均数比 ,有九个位点是 <0 .6 6 6 7,说明 相似文献
9.
目的 :建立 SD鼠脊髓下行传导束诱发电位 ( MEP)模型。 方法 :刺激颈髓段下行传导束 ,于双侧坐骨神经记录电位变化。采用 8个不同刺激强度区间 ,并结合脊髓部分损伤状态 ,评价其潜伏期和波幅的变化。结果 :诱发电位主要由 3个正负波峰组成。 N1的潜伏期 :右侧 ( 2 .89± 0 .2 2 ) ms,左侧 ( 2 .89± 0 .2 4) ms。传导速度 47.9m/s。 N1的波幅 :右侧 ( 3 .61± 2 .10 )μV,左侧 ( 3 .83± 2 .3 2 )μV。不同刺激强度组间潜伏期相差不显著 ,但组间波幅有显著性差异 (右侧 F =2 .2 2 ,df =72 0 1,P=0 .0 3 ;左侧 F =2 .11,df=72 0 6,P=0 .0 4)。 T9平面脊髓部分损伤后 ,潜伏期延长 ,右侧 14 % ,左侧 12 % ;波幅下降 ,右侧5 9 % ,左侧 3 1%。结论 :建立的颈髓段下行传导束诱发电位动物模型有效、可靠 ,重复性好。用此模型可准确地检测脊髓传导束的功能状态 相似文献
10.
目的 :为临床腹膜后手术中下腔静脉的定位和保护提供解剖学基础。方法 :解剖 5 0具成人尸体标本 ,在下腔静脉起始段 (左右髂总静脉汇合处至左肾静脉上缘之间 )对下腔静脉及其属支进行定位观测。结果 :(1)该段下腔静脉长 13.12± 1.5 1cm ,管径 2 .2 5± 0 .2 4cm。静脉属支 8.75± 2 .0 2支 ,6 6 .3%开口于该段静脉后壁 ,6 6 .4 %位于肾段。 (2 )静脉属支 :①右睾丸 (卵巢 )静脉 (84 .9% ) ,距左肾静脉上缘 3.5 6± 0 .85cm ,汇入该段下腔静脉前壁 ;②腰静脉 (10 0 % ) ,变异大 ,均不成对 ,左腰静脉 (3~ 4支 )较右侧 (2~ 3支 )多 ;③肠系膜外科静脉 (86 % ) ,距左肾静脉上缘 6 .5 4± 1.2 1cm ,从下腔静脉前壁左侧汇入 ;④右肾上腺静脉 (2 0 % ) ;⑤右付肾静脉 (2 5 % ) ;⑥右肾周静脉 (36 % ) ;⑦右膈下静脉 (6 % )。结论 :以上对下腔静脉起始段及属支的观测结果 ,为临床腹膜后影像学及各类手术提供了新的解剖学基础。 相似文献
11.
血管性痴呆患者颅脑影像学改变与认知功能障碍的关系探讨 总被引:11,自引:1,他引:10
目的探讨血管性痴呆患者颅脑影像学改变特点及其与认知功能障碍的关系.方法采用MRI技术测定30例缺血性血管性痴呆患者和30例正常对照者脑叶和海马体积.采用CT技术测定30例缺血性血管性痴呆和30例缺血性卒中对照患者脑室和脑沟线性指标.应用MMSE、BSSD和RSPM评定受试者认知功能.结果血管性痴呆组与卒中对照组和正常对照组比较,额叶和颞叶体积显著较小(P<0.05),海马结构、顶叶和枕叶体积无显著差异(P>0.05).额叶和颢叶体积减小的程度与MMSE、BSSD评分的降低呈正相关.病灶位于额叶和颞叶、多发病灶以及病灶总体积大于50 mm3的血管性痴呆患者认知功能减退更加显著(P<0.05).结论额叶和颞叶萎缩是发生血管性痴呆的危险因素.关键部位病变、病灶数量和病灶体积是影响血管性痴呆患者认知功能的重要因素. 相似文献
12.
DIAGNOSTIC VALUE OF INTERICTAL DIFFUSION-WEIGHTED IMAGING IN EVALUATION OF INTRACTABLE TEMPORAL LOBE EPILEPSY 总被引:2,自引:0,他引:2
Objective To explore the ability of interictal diffusion-weighted imaging (DWI) to localize the temporal lobe of seizure origin and to predict postoperative seizure control in patients with temporal lobe epilepsy (TLE). Methods Twenty-seven patients with intractable TLE considered for surgery and 19 healthy volunteers were studied with conventional magnetic resonance imaging (MRI) and DWI. Apparent diffusion coefficients (ADCs) of bilateral hippocampi in both TLE patients and control subjects were obtained. Lateralization to either temporal lobe with hippocampal ADC was based on the threshold values derived from±1SD of right/left ratios in normal subjects. And the postoperative pathology was reviewed. Results Hippocampal ADCs were higher on the side of surgery compared with those on the contralateral side as well as the ipsilateral side in control subjects [resected side (109.8±7.3)×10^-5 cm^2/s, contralateral side (91.7±4.7)×10^-5cm^2/s, control subjects (81.6±5.2)×10^-5 cm^2/s, all P 〈 0.01 ]. Right/left hippocampal ADC ratio and conventional MRI lateralized to the operated temporal lobe in 21 of 27 (77.8%) and in 18 of 27 (66.7%) patients. Lateralization to the surgical side was not associated with postoperative seizure control with right/left hippocampal ADC ratio ( P 〉 0.05 ). Conclusions Conventional MRI is a sensitive method to detect hippocampal sclerosis. Accuracy of the right/left hippocampal ADC ratio for lateralizing to the side of surgery is very high, but it isn't a better predictor of surgical outcome. 相似文献
13.
目的:研究海马硬化患者的MRI表现。方法:应用GE 1.5THorizon LX超导MR机及Siemens 3.0TMR机对15例病人进行多序列扫描,并对获得图象进行分析。结果:海马硬化的MRI表现有:(1)海马结构萎缩;(2)T2加权像上海马结构的高信号;(3)颞叶前部萎缩;(4)颞角扩大。结论:MRI是检测海马硬化的首选方法。 相似文献
14.
Velasco AL Boleaga B Brito F Jiménez F Gordillo JL Velasco F Velasco M 《Archives of medical research》2000,31(1):62-74
BACKGROUND: There is controversy in the literature regarding the strategy used to obtain better outcomes after performing an anterior temporal lobectomy (ATL). Some investigators prefer to reduce the risks and costs of the predictor studies despite the fact that the number of patients cured after ATL (no seizures with no medication) is relatively small. Other investigators prefer to attempt a total cure in all patients by using all available predictor studies regardless of risks and costs. The latter strategy was the aim of the present work. METHODS: The absolute (%) and relative (ratio differences) predictor values of non-invasive and invasive studies for the outcome 24 months post-ATL were determined on 22 patients suffering from intractable non-lesional temporal lobe epilepsy. RESULTS: Under these conditions, 11 (50%) patients had excellent outcomes (seizure-free, no medication), 8 ( 36%), good outcomes (only auras with medication), and 3 (13.6%), poor ou tcomes (1 with >70%-seizure reduction and two no changes in seizure frequency). Predictors of excellent (vs. poor outcome) include the following: complex partial seizures (CXP) alone or associated with secondary generalized tonic-clonic seizures; ictal motionless stare and postictal amnesia; abnormal bitemporal spikes (prominent ipsilateral to ATL) and secondary bilateral synchrony EEG activities; focal hippocampal ictal EEG activities, and the presence of focal anterior temporal delta EEG activity 3 months after ATL. Predictors of poor (vs. excellent) outcomes include the following: CXP associated with other generalized seizure types; CTS, MRI, and EEG extratemporal abnormalities, and generalized basotemporal ictal EEG activities and the presence of seizures and focal anterior temporal spikes 3 months after ATL.CONCLUSIONS: The present study corroborates that no single predictive study (including non-invasive MRI and invasive ictal EEG activity) is predictive of the success or failure of ATL. Rather, a concordant combination of non-invasive and invasive studies is more likely to be predictive of a high probability of success. The high efficiency of ATL (86% of patients seizure-free) was accomplished by using all available predictor studies. 相似文献
15.
Subacute and chronic electrical stimulation of the hippocampus on intractable temporal lobe seizures: preliminary report 总被引:7,自引:0,他引:7
Velasco AL Velasco M Velasco F Menes D Gordon F Rocha L Briones M Márquez I 《Archives of medical research》2000,31(3):316-328
Recent animal experiments show that the application of an electrical stimulus to the amygdala or hippocampus following the kindling stimulus produced a significant and long-lasting suppressive effect on this experimental model of epilepsy. This is a preliminary report on the development of a surgical neuromodulatory procedure by chronic electrical stimulation of the hippocampus (CHCS) for control of intractable temporal lobe seizures in patients in whom anterior temporal lobectomy is not advisable, i.e., patients with bilateral temporal foci or a unilateral focus spreading to surrounding cerebral regions of the dominant hemisphere.This work was divided in two main consecutive stages. In the first stage, we demonstrated that subacute hippocampal stimulation (SAHCS) blocks intractable temporal lobe epileptogenesis with no additional damage to the stimulated tissue, and in a second stage, we attempt to demonstrate that CHCS may produce a sustained, long-lasting antiepileptic condition without additional undesirable effects on language and memory. In addition, taking advantage of this unique and ethically permissible situation, we attempt to determine whether or not the antiepileptic effects of SAHCS and CHCS are due to inhibition of the stimulation of hippocampal tissue by means of a number of electrophysiological, single photon computed tomography (SPECT) perfusion, and autoradiographic techniques.SAHCS during 3-4 weeks prior to anterior temporal lobectomy applied to a critical area located either at the anterior Pes hippocampus close to the amygdala or at the parahippocampal gyrus close to the entorhinal cortex abolished clinical seizures and significantly decreased the number of interictal spikes at focus after 5-6 days. Microscopy analysis of the stimulated tissue showed no evident histopathological differences between stimulated vs. non-stimulated hippocampal tissues. Additionally, CHCS persistently blocked temporal lobe epileptogenesis for 3-4 months with no apparent additional undesirable effects on short memory. Also, inhibition of the stimulated hippocampus seems to be one of the possible mechanisms underlying the beneficial antiepileptic effects of SAHCS and CHCS. This was revealed by increased threshold and decreased duration of the afterdischarges induced by hippocampal stimulation, flattening of the hippocampal-evoked response recovery cycles, SPECT hypoperfusion of the hippocampal region, and increased hippocampal benzodiazepine receptor binding.Future studies increasing the number and time of follow-up of patients under hippocampal stimulation are necessary before considering CHCS a reliable procedure for controlling intractable temporal lobe seizures. 相似文献
16.
Turner综合征矮身材的治疗 总被引:2,自引:1,他引:1
This study was aimed to examine the growth-promoting effects of recombinant human growth hormone (r-hGH) and low dose of thyroid hormone on short stature in girls with Turner syndrome. 8 girls with Turner syndrome, at the chronological age of 8.5-14.5 years (12.3 +/- 2.1 years) and bone age of 8.3-12.7 years (9.8 +/- 1.7 years) were observed. The maximum serum GH levels in 3 patients out of 5 with provocative testing available were > or = 10 ng/ml (10.0, 10.0 and 15.52 ng/ml, respectively), and in the other 2 of the 5 patients were < 10 ng/ml (9.3 and 9.5 ng/ml). Thyroid function including T3, T4 and TSH were measured in 5 patients. The TSH in one patient was slightly higher; the T3, T4 and TSH in other patients were normal. All patients were treated with r-hGH 1.0 IU/(kg.wk) and thyroideum 15 mg/d for 6-36 months. The results showed that the growth rate after treatment was remarkably higher than that before treatment (2.2 +/- 1.1 cm/yr). The growth rates in the first 6 month, the first year, the second year and the third year were 7.9 +/- 1.6 cm/yr, 7.5 +/- 1.2 cm/yr, 6.9 +/- 0.2 cm/yr and 5.0 +/- 0.2 cm/yr, respectively. Height standard deviation score (HSDS) increased 1.3 +/- 1.1 SD, compared with that pretreatment. The annual bone age growth rate after treatment was 0.6 +/- 0.2 yr/yr (0.43-0.8 yr/yr). These data indicated that r-hGH and low dose of thyroid hormone had remarkable effects of growth-promoting in the girls with Turner syndrome. 相似文献
17.
目的 探讨颅内电极长程记录在颞叶癫痫定位、定侧中的应用,评价其临床价值.方法 2006年1月至2010年10月北京天坛医院神经外科60例经颅内电极定位的颞叶癫痫患者,电极类型采用硬膜下条状、栅状以及深部电极,手术方式包括颅骨钻孔电极植入、立体定向深部电极植入和骨瓣开颅电极植入.结果 额-颞皮层电极植入34例,额-颞前-颞枕交界电极植入7例,双颞皮层电极植入7例,深部电极联合颞叶皮层电极植入7例,颞前-颞枕交界电极植入3例,条状电极联合栅状电极植入2例.手术方式包括前颞叶切除术50例,联合额叶致痫灶切除7例,联合胼胝体切开1例,颞后枕新皮层痫灶切除联合海马杏仁核切除2例.结论 颅内电极长程记录是一种有效的检查方法和重要的定位手段,可应用于无创评估方法难以定位、定侧的颞叶癫痫. 相似文献
18.
目的研究部分去背根对神经生长抑制因子Sema3A在脊髓及其受体NP-1在备用背根节内表达的影响。方法建立猫的单侧备用背根模型,分别在术后7d、14d取L3、L5、L6脊髓节段及手术侧L6背根节进行免疫组织化学ABC法染色,同时设置正常对照组。脊髓背角内检测Sema3A免疫阳性产物的平均光密度值(OD值),背根节内计数NP-1阳性中小神经元数。结果在L3脊髓节段,Sema3A的表达术后7d(0.25±0.14)、14d(0.27±0.09)较正常对照组(0.37±0.87)减弱(P<0.05);在L5脊髓节段,Sema3A的表达术后7d(0.26±0.11)较正常组减弱(P<0.05),术后14d(0.33±0.09)时有所恢复;L6脊髓节段各组Sema3A的表达无明显变化。背根节内,术后7dNP-1阳性中小神经元数(30.85±10.26)较正常组(45.06±12.47)减少(P<0.05),14d时阳性中小神经元数(40.73±12.25)较7d时有所增加(P<0.05)。结论脊髓部分去背根后,Sema3A及其受体NP-1表达的时空变化可能与脊髓损伤后可塑性有关。 相似文献
19.
目的 探讨颅内电极长程记录在颞叶癫痫定位、定侧中的应用,评价其临床价值.方法 2006年1月至2010年10月北京天坛医院神经外科60例经颅内电极定位的颞叶癫痫患者,电极类型采用硬膜下条状、栅状以及深部电极,手术方式包括颅骨钻孔电极植入、立体定向深部电极植入和骨瓣开颅电极植入.结果 额-颞皮层电极植入34例,额-颞前-颞枕交界电极植入7例,双颞皮层电极植入7例,深部电极联合颞叶皮层电极植入7例,颞前-颞枕交界电极植入3例,条状电极联合栅状电极植入2例.手术方式包括前颞叶切除术50例,联合额叶致痫灶切除7例,联合胼胝体切开1例,颞后枕新皮层痫灶切除联合海马杏仁核切除2例.结论 颅内电极长程记录是一种有效的检查方法和重要的定位手段,可应用于无创评估方法难以定位、定侧的颞叶癫痫. 相似文献
20.
心区交感神经阻滞对严重心力衰竭左心室舒张功能的影响 总被引:11,自引:0,他引:11
目的观察心区交感神经阻滞对严重心力衰竭患者左心室舒张功能的影响。方法随机选择有严重心力衰竭,左心室射血分数<35%的扩张型心肌病患者39例,分为心区交感神经阻滞组(TEB组)和对照组。对照组给予常规抗心力衰竭治疗,TEB组在给予药物治疗的同时,予以TEB。于治疗前和治疗后1个月行超声心动图检查,测量左心房内径(Lad)、左心室内径(LVEDd)、左心室射血分数(EF),二尖瓣环6个位点心肌组织舒张早期速度和舒张晚期速度(Em和Am),并取平均值(MEm和MAm),比较两组上述指标变化。结果TEB组Lad、LVEDd显著缩小(LVEDd66mm±6mmvs71mm±6mm,P<0.05),EF显著增加(35%±7%vs23%±6%,P<0.05),二尖瓣环6个位点的Em和3个位点的Am均显著增加,MEm和MAm也显著增加(MEm5.7cm/s±1.5cm/svs7.1m/s±1.7cm/s,P<0.05),对照组Lad、LVEDd和EF无显著变化,二尖瓣环只有2个位点Em显著增加,Am、MEm和MAm均无变化。结论同常规治疗相比,TEB能在缩小严重心力衰竭患者左心室腔径、增强射血功能的同时显著改善左心室舒张功能。 相似文献