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1.
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is an effective, even the only option to cure patients with certain hematological diseases.HSCT has been applied in China for about 30 years, and great improvement has been made during the past decade.A distinctive HSCT system with Chinese characteristics has been gradually stylized, which manifested in the following aspects.  相似文献   

2.
Ketamine in a variety of combina-tions with other compound for balancedanesthesia have been administered. Fourtypes of combination have been used: (1) A single dose of ketamineinjected intravenously for induction,followed by the repeat dose of ketamineas necessary for maintenance. (2) Induction was just same as(1), followed by 0.1%-0.2% ketaminesolution with continuous intravenousinfusion for maintenance.  相似文献   

3.
For some thirty years since the founding ofthe new China,ancient therapeutic measureshave been drawn upon in formulating new treat-ment methods through clinical practice.Aimshave been to expand indications for acumoxi-bustion and heighten therapeutic effect as wellas improving acumoxibustion manipulation.Var-ious new types of acupuncture have been deve-loped.Among these are acupuncture with fili-form needle,electric needle,hydroneedle(acu-point injection with small dose of drugs),hotneedle,searing needle,digital needle,blunt-tip  相似文献   

4.
Endoscopic management of bladder neck obstruction   总被引:1,自引:0,他引:1  
Objective To evaluate endoscopic management of bladder neck obstruction (BNO). Methods 44 patients suffering from BNO have been treated by transurethral resection of bladder neck (TURN). Results All patients have been followed up for 6 - 84 months with a mean of 48 months. The success rate has been 84 %. Recurrence was observed in 4 (11%) for all of which TURN was carried out twice or three times with success. The causes of the 7 failures were neurogenic bladder, detrusor-extrasphincter dyssynergy, BNO with chronic prostatitis (CP) or BNO with chronic cystitis in female patients. Conclusion Endoscopic management is a safe and efficient treatment for BNO. Careful consideration should be undertaken in case there is CP or for female patients. Postoperative adjunctive hormone supplement therapy and long-period urethral dilatation might be needed for prevention recurrence. 6 refs.  相似文献   

5.
1. be attacked with (or by) The child was attacked with measles,这孩子得了麻疹。 2. become ill He became sefious ill,他病得很厉害。 3. be ill (with) She was ill with heart disease.她患心脏病。 4. be sick (with) He has been sick for weeks,他病了几周了。 5. be taken ill  相似文献   

6.
Pediatric cerebral palsy (PCP) is ascommon disease in paediatrics.In the litera-ture there have been many reports on thetherapeutic methods for the disease,butvery few of them on the mechanisms of thesetherapies.PCP has been treated in our hos-pital by hydroacupuncture with satisfactoryresults.Since 1987,117 PCP cases have been  相似文献   

7.
The aim of this work was empirical verificationof discordant views upon the subject of morphologicalstructure of acupuncture points(AP)and meridians.Altogether about 11 thousands of slides have been in-vestigated and they were made of 147 cuttings takenfrom 21 corpses.The slides were stained with hema-toxiline-eosine and also with silver(Shultz modifiedmethod).Then they were examined with the help ofluminous microscope.The investigation of AP mor-phological structure showed the presence of alreadyknow,typical for skin morphological structures,within these points.The most common morphologi-cal structure in AP are free nerve endings.No mor-phological structures have been noticed on the skinwhich could correspond to acupuncture meridians.It has been observed that characteristic bioelectricproperties of AP are retained after death of an or-ganism.  相似文献   

8.
Pre-pubertal periodontitis(PPP) is a rare and rapidly progressive form of early onset periodontitis resulting in premature tooth loss of primary and permanent dentitions. Mutations in cathepsin C (CTSC) gene have been found in patients with pre-pubertal periodontitis and Papillon-Lefevre syndrome which also characterized with severe periodontitis and palmoplantar hyperkera-tosis. To date. more than 40 mutations of CTSC gene have been identified in ethnically diverse people worldwide. However. there is no such genetic analysis in China. In the present study, we report the mutation analysis of a Chinese patient with PPP.  相似文献   

9.
Levonorgestrel (LNG) and naproxen have been used as active constituents for progestogen-relcasing and prostaglandin synthetasc inhibitor (PGSI) -releasing IUDs.For development of new medicated IUDs, effects of norgestimate and DPE9 have been compared with those of LNG and naproxen respectively in our institute.  相似文献   

10.
Hypertrophic cardiomyopathy (HCM) is a myocardial disorder characterized by unexplained ventricular hypertrophy and myofibrillar disarray, with a prevalence of about 0.2% in general population. HCM is associated with gene abnormalities. Nearly 200 mutations have been described in ten genes in patients with HCM  相似文献   

11.
目的评价非甾体抗炎药氯诺昔康用于妇科开腹手术后患者自控镇痛(patient-controlled analgesia,PCA)的安全性及有效性.方法选择89例择期妇科开腹手术患者,术后随机分为L组(n=30),M组(n=30)和T组(n=29),接受PCA治疗.L组使用氯诺昔康(1 mg/次,总量32 mg/24 h),M组使用吗啡(1.25mg/次,总量40mg/24 h),T组使用曲马多(12.5 mg/次,总量400mg/24 h).结果氯诺昔康组与吗啡及曲马多组的疼痛缓解评分总和(TOTPAR)分别为15.2±3.9,16.4±3.5和15.9±4.4(P>0.05),疼痛程度差值总和(SPID)分别为10.3±3.1,9.0±2.0和9.2±4 7(P>0.05).氯诺昔康组的胃肠道副作用低于吗啡和曲马多组,三组分别为3例(10.0%),8例(26.7%)和5例(17.2%).结论氯诺昔康用于妇科开腹手术后PCA的效应与吗啡和曲马多接近,可引起轻度的胃肠道症状.  相似文献   

12.
丁丙诺啡对腹部肿瘤手术后患者自控镇痛的临床研究   总被引:1,自引:0,他引:1  
①目的 评价丁丙诺啡在腹部肿瘤手术后患者自控镇痛 (PCA)的效果和安全性。②方法  1 2 0例肿瘤手术患者在手术后随机分为丁丙诺啡组 (A组 )和芬太尼组 (B组 ) ,每组均为 60例接受PCA治疗。A组使用丁丙诺啡 ,B组使用芬太尼。采用视觉模拟评分法 (VAS)评估。③结果 两组患者 2 4小时总的疼痛缓解程度 (TPR)和 2 4小时总的疼痛差值 (SPID)均无显著性差异 (P >0 .0 5) ,且无任何严重毒副作用。④结论 丁丙诺啡在腹部肿瘤手术后PCA的镇痛效应和芬太尼相同  相似文献   

13.
闫睿  武婕 《新疆医学》2012,42(8):32-35
目的:帕瑞昔布钠超前镇痛在腹腔镜直肠癌(保肛)根治术中的疗效。方法 :将60例美国麻醉师协会分级(ASA)Ⅰ或Ⅱ级择期腹腔镜直肠癌(保肛)根治术患者随机分为A、B两组,A组分别于麻醉诱导时静脉注射帕瑞昔布钠40 mg及术后12 h静脉注射帕瑞昔布钠40 mg,而B组在麻醉诱导时给予0.9%氯化钠溶液4 ml及术后12 h静脉注射帕瑞昔布钠40 mg。两组患者术后均采用芬太尼进行患者自控静脉镇痛(PCA)。观察术后12和24 h患者自控静脉镇痛(PCA)的总按压次数和PCA有效按压次数、术后2、4、6、12和24 h的疼痛强度(VAS评分)、满意程度(BCS评分)、镇痛的补救措施以及相关不良反应。结果与B组比较,A组术后12和24 hPCA总按压次数和PCA有效按压次数降低(P<0.05),术后2、4、6和12 h的VAS评分降低而BCS评分提高(P<0.05),而两组24 h疼痛强度和满意度以及有关不良反应发生率差异无统计学意义。结论:腹腔镜直肠癌(保肛)根治术超前应用帕瑞昔布钠,能减少术后芬太尼的用量,提高镇痛质量。  相似文献   

14.
为对比有无背景给药的病人自控镇痛(PCA)在开颅术后的镇痛效果,将120例择期全麻颅脑术后患者随机分为4组(每组30例):芬太尼组(Ⅰ组)、芬太尼背景组(Ⅱ组)、曲马多组(Ⅲ组)、曲马多背景组(Ⅳ组)。背景组于术后24 h停止背景给药,仅予单纯PCA。术后4、8 h、次日晨、24、48 h记录VAS、用药量、PCA按压次数、镇静程度及不良反应。结果:单纯PCA组的PCA按压次数、有效次数和VAS疼痛评分均明显高于背景组,而用药量明显少于背景组;2个背景组比较,芬太尼组的PCA按压次数、有效次数和用药量明显高于曲马多组,VAS疼痛评分无差异。提示:芬太尼和曲马多背景用药加PCA用于颅脑术后镇痛比单纯PCA镇痛效果更佳。  相似文献   

15.
剖宫产术后不同药物自控镇痛效果临床观察   总被引:1,自引:1,他引:0  
目的观察低浓度舒芬太尼、芬太尼和曲马多3种药物对剖宫产患者术后自控镇痛(PCA)的效果及不良反应。方法 60例腰硬联合麻醉下行剖宫产手术且自愿接受PCA的产妇随机分为舒芬太尼组、芬太尼组和曲马多组,每组20例。观察3组产妇术后各时点疼痛视觉模拟(VAS)评分、镇痛满意度、镇静Ramsay评级及不良反应等。结果 3组患者VAS评分、镇痛药耗量、镇静Ramsay评分、镇痛满意度评分比较差异均无统计学意义(P>0.05);3组患者恶心、呕吐、皮肤瘙痒、尿潴留等并发症的发生率比较差异也无统计学意义(P>0.05)。结论低浓度舒芬太尼、芬太尼和曲马多用于剖宫产术后PCA,均能起到良好的镇痛效果,安全性高,不良反应发生率低。  相似文献   

16.
氟比洛芬酯复合芬太尼术后镇痛的临床观察   总被引:16,自引:1,他引:16  
目的观察氟比洛芬酯复合芬太尼用于术后静脉自控镇痛的有效性和不良反应。方法择期腹部手术患者50例,手术结束后随机分为两组:对照组术毕静脉注射芬太尼0.1 mg为负荷剂量后接PCA泵,泵内药物为芬太尼1.2 mg、氟哌利多5 mg,100 ml·48 h-1;实验组术毕静脉注射氟比洛芬酯50 mg为负荷剂量后接PCA泵,泵内药物为氟比洛芬酯50 mg 芬太尼0.5 mg 氟哌利多5 mg,100 ml·48h-1。记录术后24 h内镇痛评分(VAS)、镇静评分(SS)及不良反应。结果两组镇痛效果的差异无统计学意义(P>0.05),对照组镇静度和恶心呕吐的不良反应明显高于实验组 (P<0.05)。结论氟比洛芬酯复合芬太尼用于术后静脉自控镇痛,可减少芬太尼的不良反应,提高镇痛质量。  相似文献   

17.
目的 观察小剂量NMDA受体拮抗剂氯胺酮复合芬太尼和氯诺昔康皮下镇痛(PCSA)的安全性和有效性。方法 择期在全麻下行椎弓根钉内固定术患者60例,ASAI~II级,术中均用丙泊酚+瑞芬太尼维持麻醉,术后镇痛按药物配伍不同随机分为3组(n=20):A组芬太尼0.01mg/kg+氯诺昔康0.6mg/kg,B组氯胺酮2mg/kg+芬太尼0.01mg/kg+氯诺昔康0.6mg/kg,C组芬太尼0.02mg/kg+氯诺昔康0.6mg/kg。氯诺昔康用无菌用水稀释,然后用0.9%生理盐水配制成混合药液100mL。应用PCA泵,3组术后经皮镇痛(PCSA)均采用负荷量+持续背景量+PCA量模式:负荷剂量3mL,背景剂量2mL/h,PCA剂量0.5mL,锁定时间15min。观察术后4 h (T1)、8 h (T2)、16 h(T3)、24 h (T4)、48 h(T5)各时点视觉模拟评分(VAS)、Ramsay镇静评分、血压(BP)、心率(HR)、脉搏血氧饱和度(SpO2)、呼吸频率(RR)和患者对PCA综合满意度评价及不良反应。结果 3组患者镇痛效果均良好,在术后镇痛T1时点静息和活动时VAS评分B组和C组均小于A组,差异有统计学意义(P<0.05)。B组和C组的PCA综合满意度为优的例数显著多于A组(P<0.05)。3组术后各时点Bp、HR、RR、SpO2均在正常范围内波动,差异无统计学意义(P>0.05)。各组不良反应发生率较低且差异无统计学意义(P>0.05)。结论 瑞芬太尼全麻患者应用小剂量氯胺酮复合芬太尼和氯诺昔康皮下术后镇痛安全、有效,且不良反应少。  相似文献   

18.
目的 :评价芬太尼与氯诺昔康联合平衡镇痛用于妇科开腹术后病人皮下自控镇痛 (PCSA)的效果。方法 :6 0例在全麻下行开腹妇科手术的患者 ,随机分为芬太尼组 (Ⅰ组 )、芬太尼 +氯诺昔康组 (Ⅱ组 )和氯诺昔康组(Ⅲ组 )各 2 0例行术后镇痛。用双盲法研究。观察用药后 8、12、2 4、4 8h各时间点安静、咳嗽时VAS评分 ,镇静程度 ,病人对疼痛治疗的总体满意度 ,并记录副作用和用药总剂量。结果 :Ⅱ组芬太尼和氯诺昔康的所用剂量分别与Ⅰ组和Ⅲ组比有非常显著性差异 (P <0 .0 1) ,三组安静和咳嗽时VAS评分无显著性差异 (P >0 .0 5 ) ,Ⅱ组消化道副反应发生率 (10 % )比Ⅰ组 (2 5 % )和Ⅲ组 (2 0 % )低 ;Ⅱ组病人满意度 (95 % )比Ⅰ组 (80 % )和Ⅲ组 (85 % )稍高。结论 :芬太尼与氯诺昔康联用平衡镇痛可显著减少每种药的剂量 ,PCSA效果确切 ,副作用较单一用药少 ,可作为术后PCSA的较佳配方选择。  相似文献   

19.
氯诺昔康及曲马多用于肠道手术后自控镇痛的比较研究   总被引:2,自引:0,他引:2  
目的:评价氯诺昔康及曲马多用于肠道手术后患者自控镇痛(PCA)的安全性及有效性。方法:50例在全麻下行肠道肿瘤切除术的患者,随机分为氯诺昔康组(L组)和曲马多组(T组),每组各25例。将所配制药液注入PCA泵,设定PCA泵给药速率为2ml/11,术毕时启动PCA泵进行镇痛,镇痛完毕后由患者完成对疼痛的评分,并记录发生的副作用。结果:在病人镇痛总体印象评分中,L组镇痛满意的比例略高于T组,但无统计学差异。T组恶心与呕吐的发生率明显高于L组。结论:氯诺昔康用于肠道肿瘤切除术后PCA的效果与曲马多接近,但副作用少,更适用于急性疼痛的治疗。  相似文献   

20.
目的比较芬太尼PCIA与帕瑞昔布+芬太尼PCIA应用于下腹部手术后镇痛的效果及部分不良反应发生情况.斤法28例ASAⅠ-Ⅱ级全麻下行盆、腹部手术的患者,分为A组单纯芬太尼组,B组帕瑞昔布+芬太尼组,每组14例.两组于气管导管拨除后芬太尼静脉PCA镇痛(100mL溶液内含芬太尼1mg,B组缝皮前静注帕瑞西布40mg(生理盐水4mL稀释).记录术后24h芬太尼用量、PCA的次数(实际次数及有效次数),于术后4h,24h随访病人,进行VSA评分,询问恶心、呕吐等不良反应发生情况.结果B组24hPCA次数及芬太尼用量低于A组,VAS评分术后4h两组相比,B组VAS评分低于A组:术后24h两组相比差异无统计学意义(P〉0.05).B组恶心呕吐及皮肤搔痒的实际发生频数低于A组.结论芬太尼PCIA+帕瑞昔布联合用于下腹部手术的术后镇痛安全、有效,值得在临床推广应用.  相似文献   

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