首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 46 毫秒
1.
目的了解肺炎支原体(MP)感染肺外并发症的临床特征。方法以ELISA方法检测MP-lgM≥1:80且冷凝集试验≥1:32确诊MP感染患儿共298例,对其临床资料进行回顾性分析。结果298例均有呼吸道症状,275例有肺部罗音,主要为干罗音;X线肺部摄片均有明显改变:37例呈大片状阴影,206例呈斑点状阴影,55例呈间质性肺炎改变;106例(35.57%)有肺外并发症,以消化、皮肤黏膜及淋巴、心血管、泌尿、血液、神经等系统多见,分别占20.13%、5.03%、4.03%、2.68%、1.01%,其中2.01%为川崎病。经大环内酯类抗生素治疗,治愈255例,好转43例,无1例死亡。结论MP感染可引起多系统、多脏器损伤。  相似文献   

2.
路元芳 《吉林医学》2011,(34):7214-7215
目的:为更好地了解小儿肺炎支原体(Mycoplasma Pneumoniae,MP)感染及肺外并发症的临床特征。方法:对经治疗并确诊为MP的62例患儿进行回顾性临床分析。结果:58例(93.5%)以呼吸道症状为主,其中25例(40.3%)有肺外并发症,有4例(6.5%)以肺外系统症状、体征首发。受累系统以血液、心血管、消化、泌尿等系统多见,分别为11.3%、9.7%、8.1%、3.2%。全部病例经大环内酯类抗生素规范治疗痊愈。结论:MP感染可引起多系统多脏器损害,对于常规治疗疗效不佳及有多脏器损害的呼吸系统感染者,应注意MP感染,尤其是以肺外并发症为首发症状者。  相似文献   

3.
小儿肺炎支原体肺炎肺外并发症23例临床分析   总被引:4,自引:1,他引:3  
目的:探讨小儿肺炎支原体(MP)肺炎的肺外并发症.方法:回顾分析105例肺炎的临床资料.结果:105例MP感染中,23例有肺外并发症,发生率为21.9%.主要并发症有支原体脑炎、心肌炎、泌尿系统及消化系统损害、皮疹、关节炎等.结论:MP感染可引起机体多系统损害.部分患儿可同时合并2个系统或以上的损害.少数病例肺外并发症为首发症状,易误诊、漏诊,应引起高度重视.  相似文献   

4.
目的:探讨儿童肺炎支原体(MP)肺炎临床及肺外并发症的特点.方法:分析438例儿童MP肺炎的临床特点及肺外并发症的发生情况.结果:438例中319例为学龄前期(3~6岁);153例肺外并发症中年龄≥3岁143例,3岁以下10例;并发症中以心血管、消化、神经系统多见,分别为51.0%、29.4%、17.6%;所有病例经阿奇霉素治疗14天左右好转.辅助检查:血 MP-IgM均≥1∶ 80,咽拭子MP培养阳性率32.6%.胸片肺间质改变238例,肺泡炎症121例,混合病变79例.结论:MP感染临床特征及胸部X线表现缺乏特异性,且易有肺外并发症,以肺外并发症为首发症状时,易造成误诊;对于治疗不理想且伴有肺外并发症的肺炎,应考虑MP感染可能,及时进行相关检测,早确诊,早治疗.  相似文献   

5.
目的 探讨小儿肺炎支原体(MP)感染的肺外并发症.方法 回顾分析426例 MP感染患儿的临床资料.结果 426例MP感染中,72例有肺外并发症,发生率16.9%,主要有支原体脑炎、心肌炎、泌尿系统受累、肝功能损害、粒细胞减少、皮疹等.结论 MP感染可引起机体多系统损害,部分患儿可同时有2种或2种以上的合并症,少数以肺外合并症为首发症状,易误诊、漏诊,应引起重视.  相似文献   

6.
目的:了解肺炎支原体(MP)感染肺外并发症的临床特征。方法:对350例确诊MP感染患儿的临床资料进行回顾性分析,其中肺外表现122例。结果:350例均有呼吸道症状,122例(34%)有肺外并发症,以消化系统(37.7%)、心血管系统(17.2%)、神经系统(12.2%)、泌尿系统(7.3%)、血液(5.7%)等系统多见。结论:MP感染可引起多系统、多脏器损伤。  相似文献   

7.
小儿肺炎支原体感染肺外脏器损害22例分析   总被引:1,自引:0,他引:1  
目的:探讨小儿肺炎支原体(MP)感染肺外脏器损害的临床特征。方法:回顾分析56例MP感染患儿的临床资料。结果:56例MP感染中,22例有肺外脏器损害,发生率为39.29%,主要累及消化系统、心血管系统、泌尿系统、血液系统、皮肤,分别为36.36%、31.82%、22.73%、22.73%、18.18%。结论:MP感染除引起肺部病变外,可同时有1个或1个以上肺外脏器受累,对有多脏器受累的患儿,应考虑MP感染可能,及早确诊,积极对因治疗,预后较好。  相似文献   

8.
257例小儿肺炎支原体感染肺外并发症临床分析   总被引:16,自引:0,他引:16       下载免费PDF全文
[目的]分析小儿肺炎支原体(MP)感染肺外并发症的临床特征和转归.[方法]采用ELISA方法检测血MP-IgM、IgC,对MP-IgM≥1:80且确诊为MP感染的632例患儿的临床资料进行回顾性分析.[结果]632例中257例(40.66%)发生肺外不同脏器、系统的损害,其中以消化、泌尿及血液系统多见,分别为41.25%、31.52%和20.62%.全部病例经大环内酯类抗生素治疗14 d好转.[结论]MP感染常引起肺外并发症,当以肺外表现为首发症状时,易造成误诊误治.因此对于治疗不理想及不能完全以细菌、病毒感染解释的多脏器受累的呼吸道感染,应考虑MP感染的可能,及时进行相关检查,尽早确诊.  相似文献   

9.
小儿肺炎支原体肺炎132例临床分析   总被引:6,自引:2,他引:6  
目的对小儿肺炎支原体(MP)感染所致的肺炎及肺外并发症进行探讨。方法回顾性分析132例MP感染的肺炎支原体肺炎临床资料。结果132例MP感染患儿中,有肺外并发症33例。结论MP感染能引起小儿肺炎,并可引起多系统多器官损害,易造成漏诊、误诊,我院采用金标免疫斑点试剂法监测MP-1gM,使误诊率下降,有并发症者根据病情采取综合治疗,均痊愈。  相似文献   

10.
小儿肺炎支原体感染肺外并发症50例分析   总被引:1,自引:0,他引:1  
张善梅 《医学理论与实践》2006,19(12):1455-1456
目的:探讨肺炎支原体(MP)感染的肺外并发症。方法:回顾性分析143例MP感染患儿的临床资料。结果:在143例MP感染患儿中,伴有肺外并发症的有50例。结论:MP感染可引起大量肺外并发症,故对不能完全以细菌、病毒感染解释的多脏器受累的呼吸道感染应考虑到MP感染的可能。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

19.
Objective To measure Derpl and Blot5 allergen levels in asthmatics' homes in Hongkong.Methods Seventy houses were enrolled for a mite indoor environment study. Dust samples were obtained from two sites of each patients' house: bed and floor. Derpl and Blot5 levels were quantified by a two-site monoclonal antibody-based ELISA technique.Results The levels of Derpl allergens found in bed (geometric mean (GM) 3.43 μg/g of dust; 95%CI, 1.89-4.96 μg/g)and on the floor (GM 1.12 μg/g of dust; 95%CI, 0.71-1.53 μg/g) indicated significant differences (P=0.005). However, the levels of Blot5 allergens found in bed (GM 19.00 μg/g of dust; 95%CI, 0.89-38.90 μg/g) and on the floor (GM 6.14 μg/g of dust; 95%CI, 0.40-11.90 μg/g) showed no statistically significant difference. In addition, in regards to the exposure index for Derpl and Blot5 allergens found in bed and on the floor, 17.6% in bed and 8.6% on the floor had levels of Blot5 ≥ 10 μg/g of dust, higher than those obtained for Derp1 (7.2% and 0% in bed and on the floor respectively, P< 0.05); higher percentages in bed and on the floor (25.0% and 35.7%) were observed for levels of Blot5 =0 μg/g of dust as compared with Derpl in bed and on the floor (4.3% and 14.5% respectively, P< 0.05).Conclusions Derpl and Blot5 are the major allergens found in this regional study, Blot5 is a more potent allergen in Hongkong, probably reflecting the high level of exposure to Blomia tropicalis (Bt). Bt and Dermatophagoides pteronyssinus (Dp) allergens should be included for precise diagnosis and effective immuno-therapeutic treatment of mite allergy in Hongkong.  相似文献   

20.
ANTI-PROLIFERATION EFFECT OF ORIDONIN ON HL-60 CELLS AND ITS MECHANISM   总被引:4,自引:0,他引:4  
Objcetive To investigate the anti-proliferation effect of oridonin on leukemic HL-60 cells and its mechanism. Methods HL-60 cells in vitro in culture medium were given different concentrations of oridonin. The inhibitory rate of cells were measured by microculture tetrazolium (MTT) assay, cell apoptotic rate was detected by flow cytometry (FCM), morphology of cell apoptosis was observed by hoechst 33258 fluorescence staining, and the activity of telomerase was detected using telomere repeat amplification protocol (TRAP) PCR-ELISA before and after apoptosis occurred. Results Oridonin could decrease telomerase activity, inhibit growth of HL-60 cells, and cause apoptosis significantly. The suppression was both in time- and dose-dependent manner. Marked morphological changes of cell apoptosis including condensation of chromatin and nuclear fragmentation were observed clearly by hoechst 33258 fluorescence staining especially after cells were treated 48-60 hours by oridonin. Conclusions Oridonin has apparent anti-proliferation and apoptotic effects on HL-60 cells in vitro, decreasing telomerase activity of HL-60 cells may be one of its most important mechanisms. These results will provide strong laboratory evidence of oridonin for clinical treatment of acute leukemia.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号