慢性乙型肝炎患者心理问题调查及分析

我国是乙型肝炎高发区。在我国乙型肝炎病毒携带者约有1．3亿，占我国人口的10％左右，占世界乙型肝炎病毒携带者的50％以上。由于慢性肝炎缺乏特效治疗方法，反复发作，病情迁延不愈，很多慢性乙肝患者出现一些不健康的心理状态。笔者对本院150例慢性乙肝患者心理状态进行了调查，现总结如下。     

《保肝方》治疗迁延性肝炎及慢性肝炎22例临床分析

中草药科研小组曾用中药“保肝方”治疗迁延性肝炎及慢性肝炎22例,有一定疗效。小结如下,以供参考。临床资料 1.诊断指标:凡肝炎病程迁延不愈,病期持续超过半年以上,仍有乏力、食欲减退、肝区不适、疼痛等症状,肝脏肿大及有压、叩痛、或有轻度脾肿大,肝功能检查反复不正常者,可诊断为迁延性肝炎。而肝炎病程在一年以上,症状经常出现,肝脏及脾脏肿大,肝功能检查持续或反复阳性,或蛋白成分亦见变化,诊为慢性肝炎。     

七味白术散治疗婴幼儿非感染性迁延性腹泻病15例

婴儿非感染性迁延性腹泻病是临床上常见的消化道病证。腹泻期间，其生长发育可能减慢或停止，甚至体重下降。本文报道近期应用七味白术散治疗非感染性迁延性腹泻病15例临床疗效如下。1．一般资料本组临床观察匕例，均收集自1998年7月至1999年5月本院门诊病人。年龄最小2个月，最大12个月，男性8例，女性7例，9例来自农村，6例来自城镇，病程最短2周，最长达2个月，经西药治疗无效者10例。2诊断标准参照1999年全国腹泻会议制定的诊断标准2．1．临床表现为大便决数增多，每日4～5次，多则10余次；大便塘薄反复不愈，病程2周至2个月，性状呈绿…     

重组干扰素a-2b治疗急性丙型肝炎观察

随着对丙型肝炎病毒（HCV）研究的进展，临床研究也日渐深入，急性HCV感染后约50％～87％的病例迁延不愈，其慢性化比例远高于乙型肝炎病毒感染者。我们在临床研究中发现，急性丙型肝炎自愈病例其ALT异常者约85％的病人在3个月内即可复常，病程超过3个月仍迁延不愈者极易转慢。为此，我们试用重组基因于扰素a-2b治疗了16例急性输血后丙型肝火，试图阻断其向慢性化的发展，现将结果报道如下。     

吗丁啉治疗非溃疡性消化不良34例疗效观察

1991年1月至1992年6月,在住院患者中凡符合下列标准者诊断为非溃疡性消化不良(NUD):反复上腹部饱胀、烧灼感、恶心、呕吐等消化不良症候群三个月以上,并经胃镜证实基本正常或仅有慢性浅表性胃炎而无溃疡、肿瘤等,除外肝胆疾病者。其中男36例,女28例,年龄16～73岁,病程>1年者占95％,<1年者占5％,90％以上病例以前服过胃复安治疗。分组与治疗随机分为治疗组和对照组,两组性别、年龄与病程相仿,有可比性。治疗组34例,口服     

广西肝癌高发区的散发性非甲非乙型肝炎

对来自广西肝癌高发区的204例散发急性病毒性肝炎患者研究的结果显示,非甲非乙型肝炎占47例(23％),乙型肝炎占92例(45％),甲型肝炎占63例(31％),巨细胞病毒感染占2例(1％),对2例所有乙肝病毒血清学指标均阴性的非甲非乙肝炎患者做了快速免疫电镜检查,结果在其中1例发现27nm病毒样颗粒。同时发现,有25％的急性非甲非肝炎转变成慢性。流行病学调查表明,在所有非甲非乙肝炎患者中,21.9％病前6个月内有经皮注射史,12.5％曾接触过病毒性黄疸肝炎病人,而65.6％找不到任何明确的感染途径。     

山茛菪碱、非那根、双氢克尿塞联合治疗婴幼儿非感染性腹泻

非感染性腹泻是婴幼儿时期常见病多发病,多见于1岁以下的小儿,腹泻病程常在1～2周,部分迁延2个月或更长.近几年,口服补液盐的应用及治疗方法的增多,其病死率明显下降.但腹泻迁延不愈,可引起营养不良,严重影响小儿的生长发育.目前临床常提倡在治疗该病时以微生态制剂为主.但仍能见到腹泻发作,迁延不愈,致脱水及代谢性酸中毒及其他并发症出现.为防止病情迁延加重及出现并发症,我科采用"山茛菪碱、非那根、双氢克尿塞"3种药物(简称"止泻三联")联合用药,治疗107例非感染性腹泻,获得显著效果.     

87例小儿病毒性心肌炎随访报告

对87例临床诊断为病毒性心肌炎的小儿进行了1～6年的随访。随访结果:37例治愈,19例好转,16例迁延不愈,11例有后遗症,4例死亡。30例于6个月以内恢复,1年以上不愈者病程常趋于迁延或遗有后遗症。按病情轻重将患儿分为普通型(65例)重型(19例)、暴发型(3例)。普通型大多预后良好,治愈好转率达72.31%);     

慢性乙肝患者出院的家庭护理指导

<正>慢性乙型肝炎是一种目前无特殊治愈办法的常见病及多发病,在我国乙型肝炎病毒携带者达1.3亿之多,目前慢性乙型肝炎患者有3000万之多。慢性乙型肝炎传染性强、病程长、反复发作、病情迁延不愈。尽管临床治疗积极,仍有一部患     

六枝特区慢性非传染性疾病调查

慢性非传染性疾病（noncommunicable disease）,简称慢性病,是一类起病隐匿,病程长且病情迁延不愈,缺乏确切的传染性生物病因证据,病因复杂,且有些尚未完全被确认的疾病的概括性总称。以恶性肿瘤、心脑血管疾病、慢性阻塞性肺疾病、糖尿病等为代表,     

APPLICATION OF LORNOXICAM TO PATIENT-CONTROLLED ANALGESIA IN PATIENTS UNDERGOING ABDOMINAL SURGERIES

FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…     

Dr.Zhang Ren''''s Experience in the Acupuncture Treatment of Different Diseases with the Same Therapeutic Principle

Dr.Zhang Ren,the chief physician,is the chairman of Shanghai Acupuncture and Moxibustion Association.Having been engaged in medicine for about 40 years,he is experienced in treating various intractable diseases.In his long years of clinical practice,he advocates taking the TCM differentiation as the basis to seek for the acupuncture method for treatment of modern intractable diseases.The author of this essay had the fortune to follow Dr.Zhang in study.The following is a summary of Dr.Zhang's experience in the acupuncture treatment for different intractable diseases with the same therapeutic principle.     

Luo Lingjie''''s Experience in Treating Chronic Nephropathy

In treating chronic nephropathy,Luo Lingjie,a chief physician,pays attention to regulating the balance between yin and yang,treating infection if present,and removing pathogenic factors.He prescribes gentle drugs and uses carefully strongly warming-tonifying ones,emphasizes the importance of persuading the patient to persist in treatment with medication and nurse one's health for recuperation,and is good at combined use of TCM and western medicine therapy and brings the merits of various therapies into full play,with obvious theraoeutic effects.     

Acupuncture Combined with Spinal Tui Na for Treatment of Primary Dysmenorrhea in 30 Cases

Objective: To observe the therapeutic effects in acupunture treatment of primary dysmenorrhea combined with spinal Tui Na, and study its mechanism. Methods: Thirty cases of the treatment group were treated by acupuncture combined with spinal Tui Na, and thirty cases in the control group were treated by routine acupuncture. Results: The total effective rate was 93.3% in the treatment group, and 73.3% in the control group, with a significant difference between the two groups (P<0.05). Conclusions: Acupuncture combined with spinal Tui Na has good prospects for treatment of primary dysmenorrhea.     

猪肺磷脂注射液联合经鼻持续气道正压通气对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性的影响

目的 探讨猪肺磷脂注射液联合经鼻持续气道正压通气(NCPAP)对呼吸衰竭早产儿的临床疗效及肌酸激酶同工酶活性(CK-MB)的影响.方法 选取呼吸衰竭早产儿80例,分为观察组和对照组各40例.对照组采用NCPAP给氧治疗,观察组给予NCPAP给氧联合猪肺磷脂气管内给药.观察两组患儿治疗前及治疗12h、24 h后PaO2、PaCO2、血氧饱和度(SaO2)、pH的变化情况,检测治疗前及治疗5d后血清CK-MB水平;评估两组患儿的临床治疗效果.结果 两组患儿PaO2、PaCO2、SaO2、pH比较,差异均有统计学意义(P＜0.05),其中观察组治疗后的PaO2、SaO2、pH均高于对照组,PaCO2则低于对照组.两组的PaO2、SaO2、pH均随观察时间延长而升高(P＜0.05),PaCO2均随观察时间的延长而降低(P＜0.05).观察组治疗有效率为87.5％,显著高于对照组的70.0％ (P ＜0.05).治疗5d后两组患儿血清CK-MB水平均较前降低(P＜0.05),且观察组明显低于对照组(P＜0.05).结论 猪肺磷脂注射液气管内给药联合NCPAP可以显著降低呼吸衰竭早产儿CK-MB的含量,提高治疗有效率,起到很好的呼吸循环支持作用.     

Survey and practice of reporting quality of randomized controlled clinical trials on traditional Chinese medicine

Evidence obtained from randomized controlled trials （RCTs） has been generally accepted as the gold standard in the evaluation of clinical effectiveness. Readers need to understand the trial design, implementation, results, analysis and interpretation, so as to fully Jnderstand the results of RCTs. Thus, the investigators of RCTs have to report these items in a complete, accurate and clear manner. Since 1998, we have conducted several evaluations on the reporting quality of RCTs published in Chinese journals on traditional Chinese medicine （TCM） and results have shown that there is an urgent need for higher quality RCTs on TCM.     

TCM Treatment of Ankylosing Spondylitis by Tonifying the Kidney and Strengthening the Governor Vessel

Ankylosing spondylitis is a chronic and progressive disorder with inflammation mainly involving the central axis joints. It mainly affects the cervical spine and the lumbosacral area, with the pathogenesis closely related to the kidney and the Governor Vessel (GV). TCM holds that the syndrome is deficiency in origin and excess in superficiality, which is due to insufficiency of the kidney, deficiency of GV, and blocking of the channels with the invasion of exogenous evil, leading to poor circulation of qi and blood and malnutrition of the bones, muscles and joints. The TCM method of tonifying the kidney and strengthening GV to regulate circulation of qi and blood and check the arthralgia pain should be adopted, with the Kidney-Tonifying and GV Strengthening Decoction (益肾强督汤) prescribed.     

IMPROVING P-gp EXPRESSION IN HUMAN MONONUCLEAR CELLS IN VITRO TRANSFECTED BY MULTIDRUG RESISTANCE-1 mRNA

CHEMOTHERAPY playsa greatrolein the treat- ment of malignanttumors,especiallyingynecolo- gicalones.But inanticancerchemotherapy,leuko-cytopeniaisfrequentlytheprimarydose-limitingsideeffect factor.Moreover,cancersarefrequentlychemoresistantbe-causeof overexpressionof P-glycoprotein(P-gp), which isencodedby multidrugresistancegene (MDR1 ) and detectableinup to50% ofhuman cancersand renderscellsresistancetoanticancerdrugs.The safetyand potentialtherapeuticbenefitof mdr1 gene transferredto h…