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1.
方丽  储成凤  杨明  陈龙桂  张俭 《现代医学》2006,34(2):116-118
目的评价同层动态CT增强扫描对肺癌性与肺结核性结节的鉴别诊断价值。方法选择周围型肺癌41例和肺结核球20例,病灶平扫后静脉注入对比剂,行同层动态增强CT扫描,测量增强前后病灶CT值,计算最大净增值,并观察其强化类型。结果周围型肺癌与肺结核球平扫时二者间无显著性差异(P〉0.05);增强后除195s外,二者间所有时间段的CT强化值均有显著性差异(P〈0.05);二者的最大净增值亦有显著性差异(P〈0.05)。周围型肺癌增强后各时间段强化值与其平扫CT值相比,皆有显著性差异(均P〈0.05);肺结核球增强后各时间段强化值与平扫CT值相比无显著性差异(均P〉0.05)。周围型肺癌的强化类型以中-重度结节状强化为主,肺结核球以无强化或轻度边缘性强化为主。结论同层动态CT增强扫描有利于周围型肺癌性与肺结核性结节的定性诊断。  相似文献   

2.
鲁勇  肖香佐  曾献军 《中外医疗》2012,31(34):167+169-167,169
目的研究并探讨动态CT增强扫描对孤立性肺结节(SPN)的定性价值。方法以该院及南昌大学第一附属医院2008年12月—2011年12月期间共收集的50例孤立性肺结节患者为研究对象,并对所有的患者进行同层动态CT增强扫描,分别为患者进行平扫与增强之后的15s、75s、135s以及195s测量患者的病灶CT值,进而观察患者病灶的时间—密度曲线,并对其进行统计学分析。结果小肺癌、肺炎性结节以及肺结核结节的平扫CT差异无统计学意义,增强扫描可以较为清晰的显示小肺癌与结核瘤的CT强化程度,二者差异有统计学意义。小肺癌、肺炎性结节以及肺结核结节3种疾病的密度曲线形态不同。结论动态CT强化扫描能够较为清晰的扫描出孤立性肺炎结节的特征,对于该项疾病的临床诊断具有十分重要的现实意义,是鉴别孤立性肺结节良性与恶性的有效方式,值得在临床中推广与应用。  相似文献   

3.
目的 :评价同层CT动态增强扫描在肺孤立结节外科治疗中的价值。方法 :回顾性总结手术治疗的 42例肺孤立结节病变的临床资料 ,分析CT动态增强扫描前后CT增强值的变化 ,与术后病理结果进行对照 ,研究相关性。结果 :肺癌和肺炎性结节显著强化 ,肺结核球和肺错构瘤轻度强化或不强化 ,肺癌和肺结核球在 85s和 13 5s时间段中均有显著性差异 (P <0 .0 5 )。结论 :同层CT动态增强对肺孤立性结节的鉴别极有价值 ,CT动态增强中应重视淋巴结的观察 ,术前常规进行有助于手术方案的选择  相似文献   

4.
目的探讨螺旋CT动态增强扫描在孤立性肺结节鉴别诊断中的价值。方法分析24例经手术病理证实的肺内孤立性结节的CT动态增强扫描资料,包括肺癌18例和肺结核球6例。测量各结节CT动态增强扫描中不同时间点(0s、30s、70s、120s和180s)相同层面感兴趣区的CT值,描绘并比较两种结节的CT动态增强时间-密度曲线。结果肺癌结节CT增强扫描后各时间点平均CT值较增强前增高在30Hu以上,而肺结核强化CT平均值增高在10Hu以下。两种结节的CT动态增强扫描的时间-密度曲线形态不同。结论螺旋CT动态增强扫描有助于肺癌和肺结核结节的鉴别诊断。  相似文献   

5.
目的 评价同层动态CT增强扫描技术对非钙化性肺癌结节的诊断作用。方法 选择本院2000年5月至2005年5月经病理证实的原发周围型肺癌43例,分别为腺癌28例(包括细支气管肺泡癌9例),鳞癌10例,腺鳞癌2例,小细胞未分化癌、鳞腺癌及黏液表皮样癌各1例。所有病例行同层动态CT增强扫描,并与同期行动态CT增强的肺结核球15例进行对照研究。结果 CT增强前非钙化性肺癌结节与肺结核球的CT值差异无统计学意义(P〉0.05)。非钙化性肺癌结节增强后各时间段强化值与增强前比较差异均有统计学意义(P〈0.05);非钙化性肺结核球增强后各时间段强化值与增强前比较差异无统计学意义(P〉0.05)。结论 同层动态CT增强扫描技术对良、恶性肺结节,尤其是非钙化性肺癌与肺结核瘤的鉴别诊断作用较大,可明显提高肺癌性结节的定性准确率。  相似文献   

6.
陈喜明 《中国现代医生》2012,50(19):89-90,92
目的运用同层动态CT增强扫描诊断肺孤立性结节(SPN)。方法选取30例周围型肺癌病例和12例肺结核球病例,分别行常规扫描和同层动态CT增强扫描,比较分析平扫CT和同层动态cT增强扫描结果。结果肺癌在增强CT后30~180S各期cT值均显著高于平扫CT值,且高于同期肺结核CT值,差异有统计学意义(F=133.111.P:0.000)。而肺结核在CT增强后各期CT值与平扫CT值相比差异不明显,无统计学意义(F=9.940,P=0.085)。肺癌患者中18例结节状均匀强化,12例不均匀斑片状强化,肺结核患者中有类圆形强化8例,不均匀强化2例.无强化2例。增强后肺癌诊断准确率达96.7%(29/30);肺结核准确率达83_3%(10/12)。结论SPN的同层动态CT增强扫描能够帮助鉴别诊断肺癌和肺结核。  相似文献   

7.
目的:探讨动态增强CT扫描对肺内孤立性小结节的鉴别诊断意义。方法:经手术病理证实肺内孤立小结节60例,其中小肺癌38例,炎性结节10例,结核球12例,术前均行CT平扫及注药后30s、1min、2min、3min、4min、5min、6min的动态增强扫描。根据病灶平扫CT值及不同时间增强扫描CT值,做出不同病变CT值的时间-密度曲线。结果:小肺癌与结核、炎症的平扫CT值无显著差异。结核球的强化程度明显低于小肺癌和炎性结节,但炎性结节与小肺癌的CT强化程度无显著差异。小肺癌、炎性结节和结核球三种病变增强后的时间-密度-曲线形态和强化形式不同。结论:动态增强CT扫描对肺内孤立性小结节鉴别诊断有一定意义。  相似文献   

8.
周围型肺癌的同层动态增强CT研究   总被引:1,自引:0,他引:1  
目的 研究周围型肺癌的同层动态增强CT特点。方法 回顾分析经病理证实为原发性肺癌的肺结节 3 6例 (直径≤ 4cm) ,分析其增强前后的CT值变化 ,绘制时间 密度曲线 ,观察其强化特点。结果 平扫时肺泡细胞癌CT值大于腺癌及鳞癌 (P <0 .0 5 ) ;腺癌与鳞癌相比无显著性差异 (P >0 .0 5 )。肺泡细胞癌增强后的最大CT净增值 (增强后最大CT值与平扫CT值之差 )低于腺癌和鳞癌 (P <0 .0 5 ) ;腺癌与鳞癌相比无显著性差异 (P >0 .0 5 )。增强后肺泡细胞癌、腺癌与鳞癌在 15、75、13 5、195s时间段及最大CT值均无显著性差异 ;腺癌、肺泡细胞癌以均匀强化为主 ,鳞癌以不均匀强化多见 ,甚至可出现明显坏死。结论 动态CT净增值及肺结节的强化特点对周围型肺癌的分型有一定帮助。  相似文献   

9.
目的探讨螺旋CT动态增强扫描直径≤3cm周围型肺癌血流动力学特点。方法回顾性分析我院经病理证实或临床针对性治疗有效的77例直径≤3cm孤立性肺结节病灶(其中周围型肺癌50例,肺炎性结节21例,结核球5例,转移瘤1例)患者的资料。所有患者均行螺旋CT动态增强扫描,分别于注射对比剂后8、15、22、29、36、43、50、60、90、120、180s各扫描1次,绘出病灶动态增强时间-密度曲线,计算病灶最大增强线性斜率(SS)、强化峰值(PH)、血流灌注量(BP)。结果肺癌时间-密度曲线形态主要表现为起始呈慢升,后呈急升达峰值,再慢降型;肺炎性结节时间-密度曲线形态主要表现为起始呈急升、再慢升达峰值、再慢降型;肺结核球、转移瘤的时间-密度曲线形态多呈一低平曲线。肺癌平均SS、BP、PH分别为3.12±2.11%/s、0.79±0.72ml·min-1·ml-1、39.36±16.67Hu。肺炎性结节平均SS、BP、PH分别为4.86±3.39%/s、1.28±0.98ml·min-1·ml-1、65.89±21.35Hu。结核球平均SS、BP、PH分别为0.66±0.1%/s、0.17±0.05ml·min-1·ml-1、12.75±3.75Hu。转移瘤PH为4.47Hu。结论螺旋CT动态增强扫描反映直径≤3cm周围型肺癌的血流动力学有特征性,对周围型肺癌诊断与鉴别诊断有较大临床价值。  相似文献   

10.
CT动态增强扫描对肺内孤立性小结节的鉴别诊断价值   总被引:2,自引:0,他引:2  
目的 探讨动态增强CT扫描对肺内孤立性小结节的鉴别诊断意义。方法 经手术病理证实肺内孤立小结节60例,其中小肺癌38例,炎性结节10例,结核球12例,术前均行CT平扫及注药后30S、1min、2min、3min、4min、5min、6min的动态增强扫描。根据病灶平扫CT值及不同时间增强扫描CT值,做出不同病变CT值的时间一密度曲线。结果 小肺癌与结核、炎症的平扫CT值无显著差异。结核球的强化程度明显低于小肺癌和炎性结节,但炎性结节与小肺癌的CT强化程度无显著差异。小肺癌、炎性结节和结核球三种病变增强后的时间-密度-曲线形态和强化形式不同。结论 动态增强CT扫描对肺内孤立性小结节鉴别诊断有一定意义。  相似文献   

11.
Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P< 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P< 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.  相似文献   

12.
Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P < 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (>0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P <0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P < 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.  相似文献   

13.
Objective: To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods: SD rats served as both donors and recipients. 4℃ sodium lactate Ringer's was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava (IVC) inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results: Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion: This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.  相似文献   

14.
Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.  相似文献   

15.
Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.  相似文献   

16.
A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care(~'4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.  相似文献   

17.
Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.  相似文献   

18.
FOR anesthesiologis s ,treatingpostoperativepainhas alwaysbeen a problem.Althoughopioidshave been provedtobe effective,theirsideeffectscouldnotbeignored.With thedevelopmentofscienceand pharmacology,many drugs with aspectsof satisfactoryanalgesicefficacyand couldbe welltoleratedby patientshave been developed.And lornoxicamisone of them, which isa non-steroidalanti-inflammatorydrug (NSAID ), with analgesic, anti-infl-ammatory,andantipyreticproperties.Itseliminationhalf-time(3 to 5 hours) isle…  相似文献   

19.
Journal of Nanjing Medical University (English Edition) JNMU, sponsored by Nanjing Medical University, was established in 1987. It is a bimonthly comprehensive English medical journal published locally and abroad.Since 2007, Journal of Nanjing Medical University (English Edition )was granted Elsevier the full publishing and distribution rights worldwide for the Electronic Edition, excluding the People's Republic of China.  相似文献   

20.
目的:评价使用安心颗粒对急诊经皮冠状动脉介入术(PPCI)术后生活质量的影响.方法:将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组(术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次)和对照组(仅接受基础药物治疗).所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表(MIDAS)、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果:入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异(P>0.05);出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低(P<0.05);组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低(P<0.05).两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血(P>0.05).两组发生轻度血小板减少症的患者数比较无差异(P>0.05).结论:PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.  相似文献   

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