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探讨杨绍伊《伊尹汤液经》学术思想,认为仲景论广《汤液经法》而成《伤寒论》,其书由《汤液经法》《伤寒论》、“遗论”三部分组成,论及王叔和对内容、文字进行多次编排;《胎胪药录》《平脉辨证》补充《伤寒论》内容;仲景既论“伤寒”又论“卒病”;《汤液经法》内容可概括为“一表二里之法”;对《伤寒论》重新编排,揭示了中医古籍形成及流传、发展的脉络,是研究《伤寒论》的重要著作。 相似文献
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现学界普遍认为陶弘景《辅行诀脏腑用药法要》所载《汤液经法》即为《汉书·艺文志》所载《汤液经法》,《辅行诀》以道家思想为指导,以五行体用制化图为核心,融合阴阳五行学说,将理论与临床相结合,全面论述了经方的组织制度,形成了一套完整的临床诊疗方法。《辅行诀》所载外感天行疾病用方有阴旦、阳旦、青龙、朱鸟、白虎、玄武六名,且各有大、小汤之分。阴阳二旦与四神不同,二旦补体即为助用,助用即可补体,而四神补体即为泻用,泻用即可补体,此阴阳调和,阴平阳秘之妙要也。 相似文献
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通过对《辅行诀》与《伤寒论》和《金匮要略》针灸条文比较,可知:第一,二者编写体倒和结构相似,均为方剂为主,参以针灸条文。为辅行诀针灸条文源自《汤液经法》提供了有力证据。第二,《辅行诀》中针灸条文的行文风格早于仲景所述,尤其是从其所载腧穴特点来看,《辅行诀》中针灸条文当早于仲景,腧穴内涵尚处在形成变化过程中。第三,仲景针灸学术思想较《辅行诀》针灸内容不仅面面相契,而且从各角度都有继承发展。第四,仲景又将针灸学术思想进行了发展。由上述进行推论,仲景针灸学术思想必然受到《汤液经法》针灸内容的影响。《伤寒杂病论》中针灸条文较《辅行决》而言,体现了由粗到精、由小到大、由少到多的历史发展规律。 相似文献
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乌梅丸载于《伤寒杂病论》厥阴篇,历代医家多认为其有温脏安蛔之功,临床应用范围较为局限,自清代医家柯琴提出其为厥阴病之主方后乌梅丸才被医家重视,其临床应用亦得以拓展。乌梅丸证之成因,实则归于厥阴风木气运失常,阴阳不相顺接,而非仅为蛔虫内扰所致。以《黄帝内经》“开阖枢”理论分析六经之功能,并结合《伤寒杂病论》原文可证“阴枢”实为厥阴,乌梅丸为厥阴病之主方,有顺接阴阳之功,故其可治疗厥阴枢机不利,寒热错杂之证。《辅行诀五脏用药法要》与《伤寒杂病论》二者同源,均参考了《汤液经法》所载内容,《辅行诀五脏用药法要》中补泻诸方及救逆方之组成有规律可寻,均依文中所载“汤液经法图”而成,与五行理论密切相关。该文通过探索“汤液经法图”组方规律及药物五行归属,以“汤液经法图”组方规律剖析乌梅丸,可证乌梅丸主要作用于肝、脾、心三脏,依黄帝内经五脏藏神理论,此三脏与情志调节密切相关,故以乌梅丸论治厥阴枢机不利、寒热错杂所致之情志病有据可循,文末亦列举概述近年乌梅丸治疗情志病的报道。该文为临床应用乌梅丸治疗情志病提供了思路及依据,扩展了其应用范围,古方亦能为今用。 相似文献
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1“脾在液为涎”的研究现状及存在问题《素问·宣明五气》曰:“五液化液……脾为涎”,经后世医家对其要旨的不断阐发,“脾在液为涎”已成为中医藏象理论的经典学说之一。涎为五液之一,出于口,脾开窍于口,其脉“连舌本,散舌下”(《灵枢·经脉》),故“脾主涎”。《大素·脏腑气液》曰:“脾足太阴脉,通于五谷之液,上出廉泉,故名曰涎”, 相似文献
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Zhuoxin Yang Pengdian Chen Haibo Yu Wenshu Luo Min Pi Yonggangwu Ling Wang Fuxia Yang Yanhua Gou 《Journal of traditional Chinese medicine》2013,(6):779-786
OBJECTIVE: To investigate the combinatorial ef- fects of conception and governor vessel electroacu- puncture (EA) and human umbilical cord blood-de- rived mesenchymal stem cells (HUCB-MSCs) on pathomorphologic lesion and cellular apoptosis in rats with cerebral ischemia/reperfusion. METHODS: With the HUCB-MSCs isolated, cultured and identified and the models of cerebral isch- emia-reperfusion established, the HUCB-MSCs of passage three were intracranially transplanted andthe EA at conception and governor vessels was ap- plied. The pathomorphologic lesion by hematoxy- lin-eosin staining and the cellular apoptosis by ter- minal deoxynucleotidyl transferase-mediated nick-end labeling method around the ischemic fo- cus were observed. RESULTS: The cultured adherent HUCB-MSCs ex- hibited a spindle shape and expressed MSC-specif- ic markers, with the cell purity and proliferation rate significantly increasing after the primary pas- sage. HE staining showed that there were no patho- logical changes observed in the sham surgery group. However, in the PBS transplantation group, degeneration and necrosis of a great number of nerve cells were seen. In both the HUCB-MSCs transplantation group and the HUCB-MSCs trans- plantation + EA group, reparative changes of the pathomorphism of the tissue were found. Both combination treatment and simple MSCs treat- ment were able to improve the pathomorphorlogic lesion following cerebral ischemia and reduce the abnormal TUNEL-positive numbers, with former better than latter. CONCLUSION: HUCB-MSCs improve pathological lesions and inhibit the cellular apoptosis around the cerebral ischemic area. EA at conception and governor vessels also improve pathological lesion and inhibit the cellular apoptosis in rats treated with HUCB-MSCs transplantation, which effects were superior to that of simple HUCB-MSCs trans- plantation. 相似文献
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Effects of feeding tyrosine and phenylalanine on the accumulation of phenylethanoid glycosides to Cis-tanche deserticola cell suspension culture 总被引:1,自引:0,他引:1
AIM: To investigate the effects of feeding phenylalanine (Phe) and tyrosine (Tyr) on the accumulation of total phenolic compounds and four phenylethanoid glycosides (PeGs) to a cell suspension culture of the parasitic plant Cistanche deserticola.METHOD: A cell suspension culture of C. deserticola was established and precursors of different concentrations were fed. In each group, the cell was sampled at the 24^th day after inoculation. The content of total phenolic compounds and four PeGs compounds were determined using the Folin-Ciocalteu method and an HPLC method, respectively.RESULTS: In the Phe fed cells, the maximum PeGs yield was achieved when Phe was fed at 1.5 mmol·L^-1 and the yield reached 1.13 times the control cell concentration. In the Tyr fed cells, the maximum yield of PeGs was 1.60 times of control when 0.75 mmol·L^-1 Tyr was fed to the cells. Furthermore, it was found that the salidroside yield was 4.01 times of control group when 5 mmol·L^-1 Tyr was fed.CONCLUSION: Tyr is a better precursor for PeGs accumulation compared with Phe, and the rate limiting enzymes might be involved in the Tyr branch. 相似文献
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Tao Huang Lijian Yang Shuyong Jia Xiang Mu Mozheng Wu HangYe Weizhe Liu Xinnong Cheng 《Journal of traditional Chinese medicine》2013,(6):757-760
OBJECTIVE; To observe capillary blood flow at acu- points during acupuncture treatment of primary dysmenorrhea and gain new insights into its anal- gesic mechanism. METHODS: Patients with primary dysmenorrhea were enrolled and randomly assigned to a treat- ment or control group. Subjects' symptoms were differentiated into various Traditional Chinese Medi- cine (TCM) syndromes and treated for 10 sessions with puncturing acupuncture or self-pressing right-hand Hegu (LI 4), adding other acupoints based on syndrome. Laser speckle was used tocompare the change in the vasomotor amplitude and perfusion of the capillaries in Hegu (LI 4) be- fore and during the treatment. Each subject was re- quired to finish the period pain symptoms observa- tion form, verbal rating scales, numerical rating scale, pain rating index, face rating scale, Zung self-rating depression scale, Zung self-rating anxi- ety scale, and numerical rating scale before and af- ter treatments. RESULTS: After 10 sessions, the symptom scores, pain index (PI), and visual analog scale (VAS) de- creased significantly in treatment group. The vol- ume of blood flow in Hegu (LI 4) declined slightly. No significant evidence supported that needling caused capillary contraction, but the capillary vaso- motor amplitude at Hegu (LI 4) increased remark- ably. CONCLUSION: Acupuncture can increase the capil- lary blood flow, thus promoting the flow of Qi and blood in terms of TCM theory, which facilitates pain relief. 相似文献
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1 六经病的脉证应用要略
1.1太阳病本病提纲为“太阳之为病,脉浮,头项强痛而恶寒”(1条)。提示太阳病主脉象浮,为阳证,主症为头项强痛而恶寒。
《脉经》云:“尺寸俱浮者,太阳受病也,当一二日发。以其脉上连风府,故头项痛,腰脊强。.”临证所见,太阳病独脉为寸部脉浮,尤以左寸浮明显。 相似文献
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连建伟教授现任浙江中医药大学副校长、博士生导师、中华中医药学会方剂分会主任委员、第三批和第四批全国老中医药专家学术经验继承工作指导老师,其治学严谨,学验俱丰,医术精湛,临床上擅长以调和中焦方法治疗内科疑难病。连教授认为中医治病当以辨证为要,外科疾患虽见症于体表,然四诊合参,细审其因, 相似文献
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ZHAO Ren-Ping LIN Sen-Sen YUAN Sheng-Tao YU Bo-Yang BAI Xian-Shu SUN Li ZHANG Lu-Yong 《中国天然药物》2014,(1):24-29
AIM: To investigate the anticancer activity of DT-13 under normoxia and determine the underlying mechanisms of action. METHODS: MDA-MB-435 cell proliferation, migration, and adhesion were performed to assess the anticancer activity of DT-13, a saponin from Ophiopogonjaponicus, in vitro. In addition, the effects of DT-13 on tumor growth and metastasis in vivo were evaluated by orthotopic implantation of MDA-MB-435 cells into nude mice; mRNA levels of vascular endothelial growth factor (VEGF), C-C chemokine receptor type 5 (CCR5) and hypoxia-inducible factor 1a (HIF-1a) were evaluated by real-time quantitative PCR; and CCR5 protein levels were detected by Western blot assay. RESULTS: At 0.01 to 1 umol·L -1, DT-13 inhibited MDA-MB-435 cell proliferation, migration, and adhesion significantly in vitro. DT-13 reduced VEGF and CCR5 mRNAs, and decreased CCR5 protein expression by down-regulating HIF-1 a. In addition, DT-13 inhibited MDA-MB-435 cell lung metastasis, and restricted tumor growth slightly in vivo. CONCLUSION: DT-13 inhibited MDA-MB-435 cell proliferation, adhesion, and migration in vitro, and lung metastasis in vivo by reducing VEGF, CCR5, and HIF-la expression. 相似文献