疏肝补肾汤联合来曲唑治疗多囊卵巢综合征所致不孕症临床效果观察

目的:分析疏肝补肾汤联合来曲唑治疗多囊卵巢综合征所致不孕症的临床疗效。方法:选取2016年1月-2017年12月106例医院收治多囊卵巢综合征所致不孕症患者,随机将入选106例患者分为观察组(53例)与对照组(53例)。对照组采用单药来曲唑治疗,观察组则在对照组的基础上加入疏肝补肾汤治疗。随访1年观察两组患者的临床疗效、排卵率和妊娠率等方面的比较差异。结果:观察组治疗有效率、排卵率和妊娠率均明显高于对照组(P 0.05)。结论:疏肝补肾汤与来曲唑联合应用在多囊卵巢综合征所致不孕症患者的临床治疗中具有较好的应用价值,能够有效提高患者的临床疗效、排卵率与妊娠率。     

补肾化痰祛瘀方治疗多囊卵巢综合征35例

目的:观察补肾化痰祛瘀方治疗多囊卵巢综合征的疗效.方法:选择多囊卵巢综合征患者35例,采用补肾化痰祛瘀方治疗,对照组予克罗米芬口服,观察比较两组有效率.结果:治疗组痊愈27例,有效6例,无效2例,总有效率94.29%.对照组痊愈23例,有效5例,无效7例,总有效率80%.两组疗效比较,差异有显著性意义(P＜0.05).结论:补肾化痰祛瘀方治疗多囊卵巢综合征有较好疗效.     

补肾疏肝化痰法治疗青春期肥胖型多囊卵巢综合征30例

目的:探讨补肾疏肝化痰法对青春期肥胖型多囊卵巢综合征患者肥胖相关指标的影响。方法:予符合青春期肥胖型多囊卵巢综合征的患者口服补肾疏肝化痰中药,疗程3个月,观察治疗前后患者在体重、体重指数(BMI)、月经的改善情况及瘦素(LP)、雄激素(T)的改善情况。结果:治疗后患者月经情况,LT,T水平及BMI改善明显。结论:补肾疏肝化痰法对青春期肥胖型多囊卵巢综合征疗效明显。     

疏肝补肾汤联合来曲唑治疗多囊卵巢综合征不孕症临床研究

目的:观察疏肝补肾汤联合来曲唑治疗多囊卵巢综合征不孕症的临床疗效。方法:纳入56例肝郁肾虚型多囊卵巢综合征不孕症患者作为研究对象,随机分为观察组和对照组各28例,对照组予来曲唑治疗,观察组予疏肝补肾汤联合来曲唑治疗,2组均治疗3个月经周期。观察治疗前后2组患者卵泡数量、子宫内膜厚度、卵巢体积、宫颈黏液评分及激素水平的变化,对比治疗后的临床疗效、排卵率及妊娠率。结果:观察组临床疗效总有效率为89.29%,对照组总有效率为67.86%,2组比较,差异有统计学意义(P0.05)。2组卵泡数量、子宫内膜厚度、卵巢体积、宫颈黏液情况均较治疗前有所改善,观察组卵泡数量、子宫内膜厚度值、卵巢体积值、宫颈黏液评分均高于对照组,差异均有统计学意义(P0.05)。2组黄体生成素、雌二醇、孕酮水平均较治疗前有所改善,观察组黄体生成素水平低于对照组,雌二醇、孕酮水平均高于对照组,差异均有统计学意义(P0.05)。观察组排卵率、妊娠率均高于对照组,差异均有统计学意义(P0.05)。结论:应用疏肝补肾汤联合来曲唑治疗多囊卵巢综合征不孕症,可有效增加卵泡数量、子宫内膜厚度及卵巢体积,合理调节体内激素水平,改善患者的卵巢功能和身心健康。     

针灸辅助二甲双胍治疗肥胖型多囊卵巢综合征不孕症75例

目的观察针灸辅助二甲双胍对肥胖型多囊卵巢综合征不孕症临床疗效。方法选取150例肥胖型多囊卵巢综合征不孕症患者,随机分成对照组75例和观察组75例,对治疗前后体征、实验室指标、排卵率和妊娠率进行比较,评估疗效。结果治疗6个月后,每组患者的各项疗效指标均较治疗前明显下降,组内无显著差异(P0.05);组间对比:观察组疗效更加显著;特别是观察组治疗后周期排卵率、妊娠率明显优于对照组。结论针灸辅助二甲双胍对肥胖型多囊卵巢综合征不孕症能进一步降低BMI,改善激素代谢水平,增加排卵率和妊娠率。     

火针联合左归疏肝汤对多囊卵巢综合征不孕症患者排卵情况、血清睾酮水平的影响

目的观察火针联合左归疏肝汤对多囊卵巢综合征不孕症患者排卵情况、血清睾酮(TSTO)水平及妊娠率的影响。方法依据随机数字表法将134例多囊卵巢综合征不孕症患者分为两组,对照组67例接受左归疏肝汤治疗,观察组67例接受火针联合左归疏肝汤治疗,评价两组疗效,统计排卵情况,测定血清TSTO水平,比较妊娠率、卵巢过度刺激综合征(OHSS)发生率。结果观察组总有效率明显高于对照组(P0.05);观察组排卵数量、排卵例数明显高于对照组(P0.05);治疗后两组血清TSTO水平较治疗前明显下降(P0.05),且观察组明显低于对照组(P0.05);对照组妊娠率明显低于观察组(P0.05);两组OHSS发生率比较差异无统计学意义(P0.05)。结论火针联合左归疏肝汤在增进多囊卵巢综合征不孕症患者临床疗效、增加排卵数量与排卵例数、降低血清TSTO水平、提高妊娠率等诸多方面具有突出优势。     

中药治疗痰湿型多囊卵巢综合征合并不孕症的临床观察

目的研究中药辅助治疗痰湿型多囊卵巢综合征合并不孕症的临床疗效。方法将中医辨证为痰湿型多囊卵巢综合征合并不孕症的62例患者随机分成观察组和对照组,对照组给予克罗米芬、达英-35等常规治疗,观察组在对照组基础上加用燥湿化痰补肾活血方加减治疗,观察2组治疗前后雌激素指标(FSH、LH、T、E_2)变化,并评价临床妊娠率及总体有效率。结果观察组治疗前后雌激素LH、T、E_2和FSH差值明显大于对照组,组间对比差异有统计学意义(P0.05)。观察组周期排卵率为81.3%,对照组为80.0%,2组比较差异无统计学意义。观察组妊娠率为62.5%,总体有效率为90.6%,分别高于对照组的33.3%、70.0%,比较差异均有统计学意义(P0.05)。结论常规治疗辅助燥湿化痰补肾活血方治疗痰湿型多囊卵巢综合征合并不孕症,能明显改善患者雌激素水平,提高临床妊娠率,疗效确切,具有研究推广价值。     

中西医结合治疗多囊卵巢综合征所致不孕症临床观察

目的:观察补肾化痰祛瘀中药加克罗米芬治疗多囊卵巢综合征(PCOS)所致不孕症的临床疗效。方法:将多囊卵巢综合征患者83例随机分为两组,均予相同剂量的克罗米芬治疗,治疗组同时加用补肾化痰祛瘀中药。结果:治疗组治疗后雄性激素、促黄体生成素水平较治疗前明显下降(P<0.01)。治疗组排卵率为72.9%,总妊娠率为48.8%;对照组排卵率为72.5%,总妊娠率为22.5%。两组妊娠率比较有显著性差异(P<0.05)。结论:补肾化痰祛瘀中药加克罗米芬治疗PCOS所致的不孕症疗效优于单纯用克罗米芬治疗。     

中西药合用治疗多囊卵巢综合征合并不孕症临床观察

目的:观察中西药合用治疗多囊卵巢综合征合并不孕症的临床疗效。方法:86例随机分为观察组和对照组各43例,两组均用常规西医治疗,观察组加用中药治疗。结果:总有效率观察组高于对照组(P0.05),且周期排卵率和成功妊娠率观察组均高于对照组(P0.05)。结论:中西药合用治疗多囊卵巢综合征合并不孕症可提高临床疗效,促进排卵和妊娠。     

中西医结合治疗多囊卵巢综合征不孕症临床观察

目的:观察中西医结合治疗多囊卵巢综合征不孕症的效果。方法:82例随机分为观察组和对照组各41例,两组均用常规西药治疗,观察组加用苍附益坤汤联合针刺治疗,比较两组临床疗效、治疗前后子宫内膜厚度及妊娠率。结果:总有效率观察组高于对照组(P0.05),子宫内膜厚度观察组厚于对照组(P0.05),妊娠率观察组高于对照组(P0.05)。结论:中西医结合治疗多囊卵巢综合征不孕症疗效较好。     

微波消解-电感耦合等离子体质谱法测定脉络宁注射液中25种矿物质元素

目的建立微波消解-电感耦合等离子体质谱(ICP-MS)直接稀释测定脉络宁注射液中25种矿物质元素(Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V、As、Cd和Hg)的方法。方法分别对微波消解条件和测试条件进行考察;样品经微波消解后,采用电感耦合质谱仪测定25种矿物质元素,并对测定方法学进行考察。结果确定最佳消解条件为3步缓慢升温:400 W 80℃升温10 min,保留5 min;600 W 120℃升温10 min,保留5 min;900 W 200℃升温20 min,保留20 min;25种矿物质元素在各自的线性范围内线性关系良好,r≥0.999 6,精密度、稳定性和重复性试验的RSD均符合定量分析要求;加标回收率为94.7%~106.1%,RSD在0.34%~2.79%。脉络宁注射液中检测出Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V,未检出As、Cd和Hg。结论该方法简便、迅速、准确,适用于脉络宁注射液中25种矿物质元素的同时测定。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

Yerba Mate or Paraguay Tea

正Beverages based on Ilex paraguariensis A.St.-Hil.are used in the south Brazil and other Latin American countries located at the so-called southern cone.It is known as chimarro or mate in south and southeast Brazil,tererêin     

Journal of Acupuncture and Tuina Science Instructions for Authors

The Journal of Acupuncture and Tuina Science, a journal with an international scope （IS SN 1672-3597, CN 31-1908/R, Bimonthly）, is embodied by ＇Springer Verlag＇ Database, Index Copernicus （IC） and Chinese Scientific and Technical Paper and Citations Data （CSTPCD）. You can search full text on http：//www, springerlink, com/content/1672 -3597.     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

基于ICP-MS法的加味左金丸中无机元素分析

目的 通过电感耦合等离子体质谱（inductively coupled plasma mass spectrometry,ICP-MS）法建立加味左金丸中Cd、Pb、As、Hg、Co、V、Ni、Cu、Li、Sb、Ba、Mo、Sn、Cr、Na、Mg、Al、Ca、Ti、Mn、Fe、Zn、Ga、Se、Sr、Tl共计26种无机元素的测定方法。方法 加味左金丸通过微波消解法处理后,根据相对分子质量的大小选择内标物,其中⁷Li、²³Na、²⁴Mg、²⁷Al、⁴⁰Ca、⁴⁸Ti、⁵¹V、⁵²Cr、⁵⁵Mn、⁵⁶Fe、⁵⁸Ni、⁵⁹Co、⁶³Cu、⁶⁶Zn、⁷⁰Ga、⁷⁵As、⁷⁷Se、⁸⁶Sr以⁷²Ge作为内标;⁹⁵Mo、¹¹⁴Cd、¹¹⁸Sn、¹²¹Sb、¹³⁷Ba以¹¹⁵In作为内标;²⁰²Hg、²⁰⁵Tl、²⁰⁸Pb以²⁰⁹Bi作为内标。对标准品溶液、空白溶液与供试品溶液进行分析,采用标准曲线法进行定量分析。通过ICP-MS法进行测定。结果 26种无机元素线性的相关系数r ≥ 0.999 6,检出限为0.001~1.500μg/L,定量限为0.01~5.00 μg/L,精密度与重复性试验的RSD均小于5%,平均回收率在82.64%~106.44%,RSD均小于5%。对3个厂家的12批样品进行了测定,26种元素的含量差异较大,其中Na、Mg、Ca、Fe 4种元素的含量比较高,均大于500 μg/g,Cd、Pb、As、Hg、Co、Li、Sb、Mo、Sn、Cr、Se、Tl的含量比较低,均小于1 μg/g。由结果可知,人体的常量元素,如Na、Mg、Ca的含量比较高,Cd、Pb、As、Hg等有害元素含量比较低。根据《中国药典》2020年版一部的要求,本品中Cd、Pb、As、Hg与Cu均符合规定。结论 该方法快速、准确,可以用于加味左金丸中无机元素的测定。     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.     

Erstaunliches Ergebnis einer Schädelakupunktur nach Yamamoto bei Hemihypsarrhythmie rechts

A girl, three and a half years old at the respective date, premature in 25th week of gestation, had been presented. On day three after birth, she had had a IVH III° right and left with severe involvement of parenchyma and other multiple complications, e. a. infant respiratory distress syndrome up to the 42nd day postpartum, and epileptic attacks with apnoeic events.     

Veränderungen der Herzratenvariabilität (HRV) während Low Level Lasernadelakupunktur: Placebokontrollierte Studie an 19 herzgesunden Probanden

Background

Experimental and clinical studies postulate a neurobiological mechanism of acupuncture by modulating central pain systems, neurohormones and -transmitters. It seems to be quite likely that the autonomic nervous system (ANS) plays an important mediating role in this neuromodulation.

Aim

In measuring heart rate variability (HRV), as a non-invasive approach to the ANS-function, the object of this study was to monitor probable acupuncture-induced changes of autonomic balance. The innovative technology of laser-needle acupuncture offers for the first time a stimulation method which fulfils the demands on a placebo-controlled acupuncture trial not requiring controversial sham acupuncture.

Method

19 healthy voluntary subjects underwent 3 treatments in randomized sequence, consisting of placebo-, 1-point- (PC 6) and simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle-stimulation over 20 minutes. Before, during and after placebo-/verum laser-needle acupuncture, HRV-data for normalized HF(high frequency)- and LF(low frequency)-Power (nHF, nLF) and their quotient nLF/nHF obtained by power spectrum analysis (FFT), were measured and analyzed statistically at 5 different time points (ANOVA repeated measures, p < 0,05).

Results

During both verum applications, the 1-point- (PC 6) as well as the simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle stimulation, significant changes of the ANS-activity were found in comparison to the placebo application. The most significant modification of HRV was an increase of nHF (p < 0,05 (PC 6), p < 0,0001 (PC 6, LR 3, SI 3)) as an expression of growing vagal activity during acupuncture.

Conclusion

Laser-needle acupuncture causes in 1-point-stimulation (PC 6) as well as in simultaneous 3-point-stimulation (PC 6, LR 3, SI 3) significant changes in HRV in comparison to placebo application. HRV-monitoring seems to be a suitable approach in exploration of acupuncture-induced changes of ANS and could possibly be established in combination with laser needle acupuncture as a standard for further scientific and clinical acupuncture investigations which are greatly needed.