藏药独一味(片、胶囊)的临床应用

藏药独一味[Lamzo Phlomis Rotata(Benth)Kudo]是唇形科独一味属植物独一味的根及茎或全草. 独一味药业有限公司出品的独一味片剂或胶囊是通过对藏药独一味进行系统研究后开发出来的新型药物.在临床应用中的常规剂量为1粒/次,每日3次.     

藏药独一味植物属文献计量学研究

目的 独一味是珍稀濒危藏药,本文基于文献分析探讨藏药独一味的研究现状.方法 收集2000年～2010年在国内公开发表的关于独一味的研究文献,建立文献研究数据库.结果 共检索到相关文献210篇,分布于112种期刊中.文献主题涉及临床研究(133篇)、药理研究(18篇)、成分分析(35篇)、制剂工艺(15篇)、种苗繁育和栽...     

藏药独一味治疗骨折镇痛疗效机理探讨

独一味胶囊是在藏药独一味经过化学和药理研究的基础上,总结出来具有止血,镇痛,活血化瘀,抗菌消炎等作用的新药,近年来,我们在临床上应用独一味胶囊治疗骨折早期疼痛,发现独一味胶囊在止痛和消肿方面具有独到治疗效果,现将近2年来收治有完整病例记录病历总结如下。     

藏药独一味种群结构及更新规律初步研究

目的 研究藏药独一味种群结构及更新规律.方法 采用植物种群生态学研究方法,调查独一味密度、叶展距、重量、根茎芽数目,计算样方内独一味大小结构、根茎芽生长规律.结果 独一味种群能适应退化草场生态环境.单株独一味每年更新依靠根茎芽萌发,根茎芽数目与独一味植株大小呈正相关;独一味地上部分重量与地下部分重量呈正相关.独一味种群...     

独一味和糙苏属关系的研究进展

目的:回顾分析近年来有关传统藏药独一味和糙苏属植物研究的各类文献资料,从植物形态学、孢粉学、植物化学、细胞学及植物分子系统学角度理解独一味和糙苏属的关系,为寻找独一味代用品及提取其活性物质的原料提供有益思路.     

独一味片提取工艺研究

“独一味片”是由藏药“独一味”全草提取而得到的浸膏片，用于治疗外伤及风湿性关节炎疼痛等证，临床疗效确切。本文对独一味片的提取工艺进行了筛选研究，确定了以总黄酮含量作为该工艺的质量检测方法。     

独一味止血镇痛作用临床观察

藏药独一味Lamiopholmisrotata(Benth.)Kudo是藏、蒙及纳西族民间经常用来治疗刀、枪伤、跌打损伤、浮肿后流黄水、关节炎等疾患的草药。具有止血止痛、抗菌消炎、活血化瘀的功效。独一味胶囊是天然藏药独一味的提取物。现对我院自1999-01以来应用独一味胶囊的临床疗效观察报道如下:1　病例和方法1.1　一般资料病例选择我院创伤骨科住院患者160例,随机分为三组。独一味组86人为治疗组;云南白药组42例,三七片组32人皆为对照组。病种包括各种术后患者、外伤骨折患者、软组织损伤和关节炎、腰肌劳损患者等。患者男124人,女36例。年龄在20～68…     

应用藏药独一味片止痛化瘀临床观察

藏药独一味具有活血止痛、化瘀止血功效。基础研究证明该药有镇痛、止血、抗菌和提高免疫功能等作用。用独一味片治疗外伤、手术后疼痛、痛经、功能性子宫内出血有较好疗效     

镇痛止血药独一味的研究概况

综述了近年来有关藏药独一味的化学成分、药理、临床应用的研究进展.独一味具有显著的镇痛、止血活性,是治疗手术刀口疼痛、外伤骨折、软组织扭挫伤的良药,但其有效成分的研究有待进一步开展.     

独一味胶囊在月经异常中临床应用

藏药独一味系唇形科独一味属植物，产于西藏、四川、甘肃。具有多种药用成分，主要为黄酮类、皂苷、甾醇、人体必需的17种氨基酸，以及多种微量元素。普遍认为独一味具有活血化瘀、镇痛、止血、消肿、抗炎和增强人体免疫功能的作用。药理实验表明，独一味具有良好的镇痛作用。现将其在妇科中的应用概述如下。     

基于ICP-MS法的加味左金丸中无机元素分析

目的 通过电感耦合等离子体质谱（inductively coupled plasma mass spectrometry,ICP-MS）法建立加味左金丸中Cd、Pb、As、Hg、Co、V、Ni、Cu、Li、Sb、Ba、Mo、Sn、Cr、Na、Mg、Al、Ca、Ti、Mn、Fe、Zn、Ga、Se、Sr、Tl共计26种无机元素的测定方法。方法 加味左金丸通过微波消解法处理后,根据相对分子质量的大小选择内标物,其中⁷Li、²³Na、²⁴Mg、²⁷Al、⁴⁰Ca、⁴⁸Ti、⁵¹V、⁵²Cr、⁵⁵Mn、⁵⁶Fe、⁵⁸Ni、⁵⁹Co、⁶³Cu、⁶⁶Zn、⁷⁰Ga、⁷⁵As、⁷⁷Se、⁸⁶Sr以⁷²Ge作为内标;⁹⁵Mo、¹¹⁴Cd、¹¹⁸Sn、¹²¹Sb、¹³⁷Ba以¹¹⁵In作为内标;²⁰²Hg、²⁰⁵Tl、²⁰⁸Pb以²⁰⁹Bi作为内标。对标准品溶液、空白溶液与供试品溶液进行分析,采用标准曲线法进行定量分析。通过ICP-MS法进行测定。结果 26种无机元素线性的相关系数r ≥ 0.999 6,检出限为0.001~1.500μg/L,定量限为0.01~5.00 μg/L,精密度与重复性试验的RSD均小于5%,平均回收率在82.64%~106.44%,RSD均小于5%。对3个厂家的12批样品进行了测定,26种元素的含量差异较大,其中Na、Mg、Ca、Fe 4种元素的含量比较高,均大于500 μg/g,Cd、Pb、As、Hg、Co、Li、Sb、Mo、Sn、Cr、Se、Tl的含量比较低,均小于1 μg/g。由结果可知,人体的常量元素,如Na、Mg、Ca的含量比较高,Cd、Pb、As、Hg等有害元素含量比较低。根据《中国药典》2020年版一部的要求,本品中Cd、Pb、As、Hg与Cu均符合规定。结论 该方法快速、准确,可以用于加味左金丸中无机元素的测定。     

Erstaunliches Ergebnis einer Schädelakupunktur nach Yamamoto bei Hemihypsarrhythmie rechts

A girl, three and a half years old at the respective date, premature in 25th week of gestation, had been presented. On day three after birth, she had had a IVH III° right and left with severe involvement of parenchyma and other multiple complications, e. a. infant respiratory distress syndrome up to the 42nd day postpartum, and epileptic attacks with apnoeic events.     

七味红花殊胜散对缺血再灌注肝损伤的保护作用

目的::研究七味红花殊胜敬对缺血再灌注肝损伤的保护作用.方法:在大鼠肝缺血再灌注模型上,观察七味红花殊胜散对缺血再灌注肝损伤引起的血清丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、一氧化氮(NO)含量的变化.结果:七味红花殊胜散对大鼠血清MDA、SOD、GSH与再灌组比较有明显差异(P<0.05),NO含量与再灌组比较有明显差异(P<0.05).结论:七味红花殊胜散对大鼠急性缺血再灌注肝损伤具有保护作用.     

Methodology of Canine/Feline YNSA and Tail Acupuncture

BackgroundYamamoto New Scalp Acupuncture (YNSA) is a well-known acupuncture system for human patients which was developed by Dr. Yamamoto.ObjectiveMy aim was to transpose the human YNSA map onto canines and felines.MethodI started researching a canine/feline YNSA map in 2002. I investigated approximately 3,000 canines and felines for YNSA and 2,500 for Tail Acupuncture. The ratio of canines and felines was 6 to 4. I researched and found all the equivalent points by palpating animal patients on the basis of an exact Neck Diagnosis.ResultsI nearly completed the map in 2006. The points in the occipital region are incomplete and my research is still in progress. In the process of researching canine/feline YNSA points, I accidentally found the other microsystems around the tail and named it “Tail Acupuncture”.ConclusionsYNSA and Tail Acupuncture are acupuncture systems utilizing microsystems and support each other in canines and felines. The merits of YNSA and Tail Acupuncture are 1) immediate effects, such as in cases of lameness, 2) simplicity in finding the exact points to treat and 3) the scalp and the tail can be utilized separately or together as treatment zones, according to the situation.     

Chinesische Orthopädie: Teil 1: Die Zukunft der Akupunktur in der Postmoderne

The locomotor system is one of the major fields of application for acupuncture. The results of the large acupuncture studies funded by German Health Insurances from 2000 until 2006 are impressive and repressive: they restrict acupuncture application by allocation of reimbursement and create the necessity of reorientation, since acupuncture can neither be adequately described nor prescribed solely on the basis of disease entities. Regarding these disease entities, it seems rather necessary to analyse the layers of problems and formulate a hierarchy of therapeutic goals instead. Only in this way the effects of acupuncture, related techniques and further therapeutic modalities can be matched with the set of objectives. The article presents general principles and follows their application from biological aspects to implications for the locomotor system and consequences for the application of physical therapy. The manual of acupuncture focuses on therapeutic effects and objectives first, and then goes on to sketch simple therapeutic strategies and finally complex approaches within acupuncture. These may encompass acupuncture, microsystem acupuncture and complex therapeutic modes.     

Patientin mit chronisch rezidivierenden Gelenks- und Wirbelsäulenschmerzen

Background

Acupuncture as a regulative therapy is well-suited for the treatment of functional, reversible disorders. Additionally, the WHO recommends its application for pain therapy in cases of arthritis and back pain due to various causes. This case study should clarify which paths to take in the case of a multi-morbid patient suffering from chronic pains due to polyarthrosis.

Objective

Pain reduction and improvement of quality of life as well as improvement of sleep quality.

Methods

Annual treatment series consisting of 10 sessions each, one session per week.

Results

short-term pain reduction before undergoing endoprosthetic surgery; considerable improvement of general status and sleep.

Conclusions

Acupuncture may bring temporal relief in cases of chronic pain due to osteoarthritis and should therefore be applied in combination with western medicine. Acupuncture is particularly well-suited to treat the co-emergent vegetative symptoms.     

Fallbericht: Patientin mit Schlafstörung

Background

Since the onset of her menopause about ten years ago, a sixty-year old patient has been suffering from hot flashes and sleep disorders causing her to become increasingly anxious and nervous. As the patient's mother had died of breast cancer, substitution of hormones was not advisable. Relaxation methods such as Yoga and Autogenic Training could only mildly alleviate the symptoms.

Objective

To effectively treat the sleep disorder, improve quality of life, lessen frequency and severity of hot flashes

Methods

Weekly sessions with ear- and body acupuncture for ten weeks

Results

After the third acupuncture session the patient reported a decrease of nightly waking episodes but suffered from acute pain in the neck as well as shoulder region. After nine therapy sessions, the patient reported a 50% decrease of nightly waking episodes. The hot flashes, however, remained unchanged.

Discussion

In this case, acupuncture significantly improved the patient's sleeping disorder. It also reduced the symptoms of anxiety and nervousness. Other menopausal symptoms such as hot flashes and dryness of mucous tissues, could not be influenced.     

常见证候荷瘤小鼠神经内分泌免疫组织基因转录的总体特征

目的揭示常见证候荷瘤小鼠神经-内分泌-免疫组织基因转录的总体特征。方法采用小鼠标准化四诊及辨证方法，及Gene Chip Mouse Exon1．0ST Array等技术，检测H22荷瘤小鼠早期邪毒壅盛（邪毒）和气虚、中期阳气虚、中晚期气阴阳虚等4个常见证候下丘脑、垂体、肾上腺、睾丸、脾脏、胸腺、肿瘤RNA的转录与剪接。结果正常昆明种雄性小鼠下丘脑、垂体、肾上腺RNA电泳的28S峰低于18S，而睾丸、脾脏、胸腺、肿瘤相反。肿瘤发生的早期，下丘脑、垂体、肾上腺基因表达模式发生显著改变，邪毒尤甚，出现了失代偿。下丘脑28SRNA迅速抬升并持续，气虚强于邪毒。垂体RNA总量降低，28S陡降，邪毒尤甚。肾上腺RNA电泳特征类似垂体，气虚与邪毒相近，中晚期气阴阳虚尤甚。睾丸变化不明显。随着病情发展，脾脏重量持续增加，而胸腺相反，重量持续下降，蛋白合成和糖代谢下降。肿瘤组织蛋白合成与糖代谢，邪毒大于气虚。以上7个组织与正常对照组相比，有9127个基因表达发生差异、51126个外显子剪接发生差异。结论神经-内分泌-免疫网络组织基因转录的差异是荷瘤小鼠不同证候内在重要的物质基础。