共查询到18条相似文献,搜索用时 156 毫秒
1.
该文对半红树玉蕊地上部分的化学成分进行了研究,运用硅胶柱色谱、Sephadex LH-20凝胶柱色谱、HPLC等方法从半红树玉蕊的甲醇冷浸提取物中分离得到12个化合物,利用理化常数测定和各种谱学(NMR,MS)数据分析等鉴定其结构分别为3-O-反式对-香豆酰马斯里酸(3β-p-E-coumaroymaslinic acid,1),顺式-careaborin(cis-careaborin,2),careaborin(3),马斯里酸(maslinic acid,4),2α,3β,19α-三羟基-12-烯-24,28-齐墩果酸(2α,3β,19α-trihydroxyolean-12-ene-24,28-dioic acid,5),3-O-顺式对-香豆酰科罗索酸(3β-p-Z-coumaroylcorosolic acid,6),科罗索酸(corosolic acid,7),1α,2α,3β,19α-四羟基-12-烯-28-乌苏酸(1α,2α,3β,19α-tetrahydroxyurs-12-en-28-oic acid,8),19α-羟基熊果酸(19α-hydroxyl ursolic acid,9),3α,19α-二羟基-12-烯-24,28-乌苏酸(3α,19α-dihydroxyurs-12-en-24,28-dioic acid,10),委陵菜酸(tormentic acid,11),3-羟基-7,22-二烯-麦角甾醇(3-hydroxy-7,22-dien-ergosterol,12)。化合物1~4,7~12均为首次从玉蕊属中分离得到的化合物。以上化合物对MCF-7(乳腺癌细胞株)和A549(人肺腺癌细胞)均无明显的细胞毒作用(IC5050 mg·L-1)。 相似文献
2.
目的研究荔枝草Salvia plebaia的化学成分。方法利用硅胶色谱、Sephadex LH-20色谱等方法进行分离纯化,通过理化鉴别和波谱方法鉴定化合物结构。结果从荔枝草中分离鉴定了10个化合物,分别为β-谷甾醇(β-sitosterol,1)、齐墩果酸(oleanic acid,2)、粗毛豚草素(hispidulin,3)、2α,3β,24-三羟基-12-烯-28-齐墩果酸(2α,3β,24-trihydroxy-olea-12-en-28-oic acid,4)、3,4-二羟基苯甲酸(3,4-dihydroxy benzoic acid,5)、2α,3β-二羟基-12-烯-28-乌苏酸(2α,3β-dihydroxy-urs-12-en-28-oic acid,6)、2α,3β-二羟基-12-烯-28-齐墩果酸(2α,3β-dihydroxy-olea-12-en-28-oic acid,7)、高车前苷(homoplantaginin,8)、印度荆芥苷(nepitrin,9)、β-胡萝卜苷(β-daucosterol,10)。结论化合物2、4~7为首次从该植物中分得,化合物4为首次从该属植物中分得。 相似文献
3.
蓝萼香茶菜三萜成分的研究 总被引:7,自引:1,他引:7
从蓝萼香茶菜Rabdosia japonica var.galaucocalyx茎叶的醋酸乙酯部分分得9个化合物,利用现代波谱学方法进行了结构鉴定,它们分别是:软木三萜酮(Ⅰ),3β,28-二羟基乌苏烷(Ⅱ),熊果酸(Ⅲ),3β-乙酰氧基-12-烯-28-乌苏酸(Ⅳ),2α,3α-二羟基-12-烯-28-乌苏酸(Ⅴ),2α,3α,23-三羟基-12-烯-28-乌苏酸(Ⅵ),齐墩果酸(Ⅶ),β-谷甾醇(Ⅷ),β-胡萝卜苷(Ⅸ)。化合物Ⅰ,Ⅱ,Ⅳ,Ⅴ,Ⅵ为首次从该植物中分离得到。 相似文献
4.
目的 对白花泡桐叶的三萜类化学成分进行分离与鉴定。方法 利用硅胶柱色谱进行分离纯化,通过波谱分析鉴定其结构。结果 从白花泡桐叶的乙酸乙酯部分分离鉴定了11个三萜类化合物,分别鉴定为:2α,3β,19β-三羟基-乌苏酸-28-O-β-D-吡喃半乳糖苷(1,3α-羟基-乌苏酸(2,19α-羟基-乌苏酸(坡模酸(3,乌苏酸(熊果酸(4,23-羟基-乌苏酸(5,2α,3α-二羟基-12-烯-28-乌苏酸(6,3β,28-二羟基-乌苏烷(7,2α,3α,23-三羟基-12-烯-28-乌苏酸(8,2α, 3β, 19, 23-四羟基-12-烯-28-乌苏酸(9,2α-羟基-齐墩果酸(山楂酸(10,arjunic acid(11。结论 化合物3,5~11为首次从该植物中分离得到。 相似文献
5.
目的 研究日本路边青Geum japonicum全草的化学成分.方法 以硅胶柱色谱、凝胶柱色谱等多种色谱方法分离,制备高效液相色谱,纯化得到单体化合物,以各种有机波谱鉴定化合物结构.结果 分离得到14个化合物,鉴定为坡模酸(pomolic acid,Ⅰ)、1β,2α,19α-trihydroxy-3-OXO-12-ursen-28-oic acid(Ⅱ)、3β-O-trans-ferulyl-2α,19α-dihydroxy-urs-12-en-28-oic acid(Ⅲ)、2α-羟基乌苏酸(corosolic acid,Ⅳ)、2v,3β,19v,23-四羟基乌苏-12-烯-28-酸(V)、乌苏酸(ursolic acid,Ⅵ)、2α-羟基齐墩果酸(maslinic acid,Ⅶ)、2α,19α-dihydroxy-3-oxo-12-ursen-28-oicacid(Ⅷ)、2α,3β,19α-三羟基乌苏-12-烯-28-酸(tormic acid,Ⅸ)、蔷薇酸(euscaphic acid,Ⅹ)、goreishic acid(Ⅺ)、swinhoeic acid(Ⅻ)、β-谷甾醇(β-sitosterol,ⅩⅢ)、胡萝卜苷(daucosterol,ⅩⅣ).结论 化合物Ⅰ~Ⅲ、Ⅺ~ⅩⅣ为首次从日本路边青中分离得到. 相似文献
6.
目的研究白木通藤茎的化学成分。方法通过反复硅胶柱色谱、ODS柱色谱和重结晶的方法分离纯化,根据化合物的理化性质和波谱数据鉴定结构。结果分离得到5个化合物,分别为2α,3,β23,29-tetrahydroxyolean-12-en-28-oic acid(Ⅰ),齐墩果酸-3-O-β-D-吡喃葡萄糖-(1→3)-α-L-吡喃阿拉伯糖苷(Ⅱ),齐墩果酸-3-O-β-D-吡喃葡萄糖-(1→2)-α-L-吡喃阿拉伯糖苷(Ⅲ),3-O-β-D-glucopyranosyl-(1→2)-α-L-arabino pyranosyl-30-norolean-12-en-28-oic acid(Ⅳ),3-O-β-D-葡萄糖-(1→3)-α-L-阿拉伯糖-常春藤皂苷(Ⅴ)。结论5个化合物均为首次从本植物中分离得到。 相似文献
7.
8.
9.
糙苏根的化学成分研究 总被引:4,自引:1,他引:3
目的:研究糙苏根的化学成分.方法:用硅胶柱色谱、凝胶柱色谱等多种柱色谱分离,制备高效液相色谱纯化,得到单体化合物,用各种有机波谱鉴定化合物结构.结果:分离得到13个化合物,鉴定为齐墩果酸(oleanolic acid,1),2α-羟基乌苏酸(corosolic acid,2),3β,23-二羟基-12-烯-28-齐墩果酸(hederagenin,3),2α,3β,23-三羟基-12-烯-28-齐墩果酸(arjunolic acid,4),2α,3β,23,24-四羟基-12-烯-28-齐墩果酸(belleric acid,5),3β-hydroxy-29-al-12-en-28-oleanoic acid(6),butyrospermol (7),β-谷甾醇(β-sitosterol,8),β-胡萝卜苷(daucosterol,9),咖啡酸(caffeic acid,10),3-甲氧基4-羟基-苯甲酸(vanillic acid,11),对羟基苯甲酸(p-hydroxy-benzoic acid,12),3,4-二羟基-苯甲酸(3,4-dihydroxy-benzoic acid,13).结论:化合物3~9,11~13为首次从糙苏中分离得到的化合物. 相似文献
10.
广西产美味猕猴桃根正丁醇部位化学成分研究 总被引:4,自引:0,他引:4
目的:研究广西产美味猕猴桃根正丁醇部位的化学成分。方法:应用色谱技术分离纯化,根据理化性质和波谱数据鉴定化合物结构。结果:从美味猕猴桃根正丁醇部位中分离并鉴定了6个化合物,分别为毛花猕猴桃酸B(1),2α,3β,24 -三羟基-12-烯-28-乌苏酸(2),2α,3α,24 -三羟基-12-烯-28-乌苏酸(3),2α,3α,23-三羟基-12,20(30)-二烯-28-乌苏酸(4),2α,3α,24-三羟基-12,20(30)-二烯-28-乌苏酸(5),正丁基-O-β-D-吡喃果糖苷(6)。结论:化合物1~4,6均为首次从该植物中分离得到,其中化合物6为首次从猕猴桃属植物中分得。 相似文献
11.
An investigation on the constituents of the callus tissues of Ternstroemia gymnanthera has led to the isolation of five phytosterols, 15 known triterpenoids, and four new triterpenoids (1-4). The new compounds were characterized by spectroscopic study as 3-epi-corosolic acid lactone (2 alpha,3 alpha-dihydroxyurs-11-en-13 beta,28-olide) (1), 3-epi-ternstroemic acid (2 alpha,3 alpha-dihydroxyurs-12-en-11-on-28-oic acid) (2), ternstroemic acid (2 alpha,3 beta-dihydroxyurs-12-en-11-on-28-oic acid) (3), and gymnantheraic acid (2 alpha,3 alpha-dihydroxy-11 alpha-methoxyurs-12-en-28-oic acid) (4). The isolated triterpenes were compared with those from actinidiaceous plant callus tissues from a chemotaxonomic point of view. 相似文献
12.
13.
Three new triterpenes from Nerium oleander and biological activity of the isolated compounds 总被引:4,自引:0,他引:4
Fu L Zhang S Li N Wang J Zhao M Sakai J Hasegawa T Mitsui T Kataoka T Oka S Kiuchi M Hirose K Ando M 《Journal of natural products》2005,68(2):198-206
New ursane-type triterpene 1, oleanane-type triterpene 2, and dammarane-type triterpene 15 were isolated from the leaves of Nerium oleander together with 12 known triterpenes, 3beta-hydroxy-12-ursen-28-oic acid (ursolic acid, 3), 3beta,27-dihydroxy-12-ursen-28-oic acid (4), 3beta,13beta-dihydroxyurs-11-en-28-oic acid (5), 3beta-hydroxyurs-12-en-28-aldehyde (6), 28-norurs-12-en-3beta-ol (7), urs-12-en-3beta-ol (8), urs-12-ene-3beta,28-diol (9), 3beta-hydroxy-12-oleanen-28-oic acid (oleanolic acid, 10), 3beta,27-dihydroxy-12-oleanen-28-oic acid (11), 3beta-hydroxy-20(29)-lupen-28-oic acid (betulinic acid, 12), 20(29)-lupene-3beta,28-diol (betulin, 13), and (20S,24R)-epoxydammarane-3beta,25-diol (14). On the basis of their spectroscopic data, the structures of the new compounds 1, 2, and 15 were established as 3beta,20alpha-dihydroxyurs-21-en-28-oic acid, 3beta,12alpha-dihydroxyoleanan-28,13beta-olide, and (20S,24S)-epoxydammarane-3beta,25-diol, respectively. The anti-inflammatory activity of the seven isolated compounds and methyl esters of ursolic acid and oleanoic acid in vitro was examined on the basis of inhibitory activity against the induction of the intercellular adhesion molecule-1 (ICAM-1). The anticancer activity of the 14 isolated compounds, including 1, 2, 15, and methyl esters of ursolic acid and oleanolic acid in vitro was examined on the basis of the cell growth inhibitory activities toward three kinds of human cell lines. 相似文献
14.
??OBJECTIVE To study the chemical constituents from the roots of Rubus parvifolius. METHODS Various chromatographic techniques such as silica gel, Sephadex LH-20, and prep-HPLC column chromatography were used. RESULTS Nineteen compounds, including 12 triterpenoids were isolated from the roots of Rubus parvifolius. Based on the analysis of their spectroscopic data, the structures of these 19 compounds were identified as p-hydroxybenzoic acid(1), 4-hydroxy-3,5-dimethoxybenzoic acid(2), 3-methoxy-4-hydroxybenzoic acid(3), ??-sitosterol(4), oleanolic acid(5), ursolic acid(6), 2-oxopomolic acid(7), pomolic acid(8), p-hydroxyphenylethyl alcohol(9), psiguanin A(10), 2??-hydroxyursolic acid(11), tormentic acid(12), 2??,3??,19??,23-tetrahydroxyurs-12-en-28-oic acid(13), L-epicatechin(14), 2??,3??,19??,24- tetrahydroxyolean-12-en-28-oic acid(15), 2??,3??,19??,24-tetrahydroxyurs-12-en-28-oic acid(16), 2??,3??,19??-trihydroxyolean-12-en-23,28-dioic acid(17), suavissimoside R1 (18), and daucosterol(19), respectively. CONCLUSION Compounds 1-3, 5, 7-10, 12, and 15-17 are isolated from the roots of R. parvifolius for the first time. Compounds 7 and 9 are isolated from the genus Rubus L. for the first time. Compounds 10 and 15-17 are isolated from the family Rosaceae for the first time. 相似文献
15.
16.
17.
金毛七化学成分研究 总被引:1,自引:0,他引:1
目的:研究金毛七Astilbe myriantha的化学成分。方法:运用柱层析、重结晶等多种分离技术,根据理化性质和波谱数据鉴定化合物的结构。结果:从金毛七95%乙醇提取物中分离得到10个化合物,分别鉴定为:β-谷甾醇(1)、对羟基苯甲酸甲酯(2)、阿魏酸(3)、岩白菜素(4)、没食子酸(5)、(+)-儿茶素(6)、3β-acetoxy-6β-hydroxy-olean-12-en-27-oic acid(7)、3β-hydroxyolean-12-en-27-oic acid(8)、3β,6β-dihydrolean-12-en-27-oic acid(9)和3β-hydroxyurs-12-en-27-oic acid(10)。结论:化合物1~7为首次从该植物中分离得到。 相似文献
18.
Three new triterpenoids, designated as acinospesigenin-A (1), -B (2), and -C (3), isolated from the berries of Phytolacca acinosa, have been characterized as 3 beta-acetoxy-11 alpha,23-dihydroxytaraxer-14-en-28-oic acid, olean-12-en-23-al-2 beta,3 beta-dihydroxy-30-methoxycarbonyl-28-oic acid and olean-12-en-23-al-2 beta,3 beta,11 alpha-trihydroxy-30-methoxycarbonyl-28-oic acid, respectively. The compounds have shown antiedemic activity (LD(50) 10-15 mg/kg mass) in albino rats. 相似文献