中西医对肛瘘术后创面的治疗概况

从中医和西医两方面对临床有关促进肛瘘术后创面愈合的研究进行归纳和总结,经过分析和说明,全面地总结了近年临床的研究成果,并对中西医结合治疗肛瘘术后创面进行了初探,对现阶段存在的问题和对策进行了总结。     

老年人和脾虚患者消化系统功能的观察

本文采用胰功肽和 D-木糖试验作为消化吸收的指标,对老年人和脾虚患者进行了临床观察,并与正常组进行了比较。结果初步表明老年人和脾虚患者均有不同程度的消化吸收功能障碍,并对产生这种障碍的机理进行了初步的讨论。     

中药化妆品的研发现况与发展前景

对中药化妆品的概念、历史渊源、分类和特点与优势进行了概述,从国内和国际两个角度对其研发现状进行了详细地介绍,并简要的介绍了我国中药化妆品的申报审批制度,最后从研发、上市面临的问题和研发策略两个方面对我国中药化妆品的发展前景进行了探讨和建议。     

《核磁共振波谱法》在研究生教学中的问题分析

硕士研究生课程《核磁共振波谱法》教学过程中的一些常见和重要问题进行了讨论,并对自己的教学心得进行了总结和归纳。     

西红花活络油的制备与质量控制初步研究

对西红花活络油的制备和质量控制进行了初步研究。对其中主要成分进行了薄层确认和光谱鉴别。     

美洲凌霄的栽培与利用

首先对美洲凌霄的植物学特征进行了描述,然后重点对繁殖方式和栽培管理要点进行了总结,最后对其在园林、医药等方面的应用方式和价值进行了探讨,旨在对美洲凌霄的资源开发和利用提供依据。     

中医药多媒体资源分类与元数据探讨

对中医药多媒体信息资源及其发展现状和存在问题进行了概述,并阐述了中医药媒体资源分类和元数据规范建设的必要性,在此基础上对多媒体资源的分类和元数据规范进行了探讨,并提出了可供参考的中医药多媒体资源的分类体系和元数据规范。     

槲皮素硫酸酯钠的合成与精制

目的:为提高槲皮素的水溶性,探讨及改进槲皮素硫酸酯钠的合成和精制方法。方法:以槲皮素和硫酸为原料进行磺化反应制备槲皮素硫酸酯钠,并对产物进行精制和检测。结果:得到了合成及精制产物。结论:合成得到了槲皮素硫酸酯钠,并进行了结构确证。     

辨证论治的思考

从全新的角度对中医辨证论治的内涵和外延进行了阐述。对病、证、症、证候和症候群的概念进行了明确和区分,从中西医对比的角度阐释了辨病论治和辨证论治的不同,从而从发展的角度揭示出辨证论治的全新内涵。在此基础上,对中医临证和基础研究的方法论问题进行了探讨。     

针刺治疗心律失常的研究进展

心律失常是一种常见的临床疾病,针灸在治疗和预防心律失常方面近二十年来积累了大量的经验,在针灸治疗心律失常的机理方面也进行了很多有意义的探索,就此进行综述并对存在的问题和前景进行了评述.     

HPLC．DAD法测定银屑优化颗粒中芍药苷、甘草苷、落新妇苷、迷迭香酸和甘草酸

目的建立同时测定银屑优化颗粒中芍药苷、甘草苷、落新妇苷、迷迭香酸和甘草酸5种成分的HPLC-DAD测定方法。方法采用高效液相色谱波长切换法。Lichrospher C18色谱柱（250mm×4．6mm,5μm）;流动相为乙腈-0．1％磷酸溶液,梯度洗脱;检测波长在230、254、290nm切换;体积流量为1mL／min;柱温为30℃;进样体积10μL。结果5种成分的线性关系良好。芍药苷在69．12~691．20ng线性关系良好,平均加样回收率为97．45％,RSD值为1．54％;甘草苷在39．02~390．20ng线性关系良好,平均加样回收率为97．10％,RSD值为1．90％;落新妇苷在30．03~300．30ng线性关系良好,平均加样回收率为99．98％,RSD值为1．22％;迷迭香酸在7．82~78．20ng线性关系良好,平均加样回收率为100．83％,RSD值为1．36％;甘草酸在31．09～310．90ng线性关系良好,平均加样回收率为97．52％,RSD值为1．49％。结论本方法具有方法简便、快速、准确等特点,可同时测定银屑优化颗粒中5种活性成分。     

半夏厚朴汤君臣佐使配伍对和厚朴酚与厚朴酚含量的影响

目的:研究半夏厚朴汤君臣佐使相关配伍对抗抑郁有效成分和厚朴酚与厚朴酚含量的影响,以期分析与抗抑郁成分变化的关系。方法:采用高效液相色谱法测定半夏厚朴汤及其君臣佐使相关配伍水煎液中和厚朴酚及厚朴酚的含量。结果:佐以茯苓后提高了君臣配伍中和厚朴酚与厚朴酚含量,佐以生姜则降低君臣配伍中和厚朴酚与厚朴酚含量。使以紫苏叶未显著影响君臣配伍中和厚朴酚与厚朴酚含量。而在半夏厚朴汤全方君臣佐使配伍中缺少佐、使药之一时,其和厚朴酚与厚朴酚含量却明显降低。结论:半夏厚朴汤君臣佐使药配伍与其抗抑郁有效成分含量存在一定的内在关系。     

Caffeic acid phenethyl ester: A review on its pharmacological importance,and its association with free radicals,COVID-19, and radiotherapy

Caffeic acid phenethyl ester (CAPE), a main active component of propolis and a flavonoid, is one of the natural products that has attracted attention in recent years. CAPE, which has many properties such as anti-cancer, anti-inflammatory, antioxidant, antibacterial and anti-fungal, has shown many pharmacological potentials, including protective effects on multiple organs. Interestingly, molecular docking studies showed the possibility of binding of CAPE with replication enzyme. In addition, it was seen that in order to increase the binding security of the replication enzyme and CAPE, modifications can be made at three sites on the CAPE molecule, which leads to the possibility of the compound working more powerfully and usefully to prevent the proliferation of cancer cells and reduce its rate. Also, it was found that CAPE has an inhibitory effect against the main protease enzyme and may be effective in the treatment of SARS-CoV-2. This review covers in detail the importance of CAPE in alternative medicine, its pharmacological value, its potential as a cancer anti-proliferative agent, its dual role in radioprotection and radiosensitization, and its use against coronavirus disease 2019 (COVID-19).     

莪术行气破血、消积止痛的相关药理研究

目的 探讨莪术的传统中药药性与现代药理学研究的相关性.方法 通过查阅中国期刊全文数据库(CNKI)、中国生物医学文献数据库(CBM)、万方数据库和维普全文数据库,汇总1989～2007年间莪术的药性与药理的相关文献,对莪术的中药药性(如性味、归经、功效等)与现代药理学研究进行归纳分析,探讨两者之间的相关性.结果 莪术行气、破血、消积,具有抗肿瘤、改善血液流变学、抗炎、抗病毒及抗肝损伤等作用;温中止痛可改善脾胃及子宫功能;归肝脾经可增强免疫.结论 莪术的传统中药药性与现代药理作用有吻合之处,但还有待于进一步探讨,从而为莪术的临床应用提供更好依据.     

Antiinflammatory,Antioxidant, and Immunological Effects of Carum copticum L. and Some of Its Constituents

Carum copticum L. has been used traditionally for its various therapeutic effects. The plant contains various components such as thymol and carvacrol. Different therapeutic effects such as antifungal, antioxidant, antibacterial, antiparasitic, and antilipidemic were described for the plant and its constituents. Therefore, antiinflammatory, antioxidant, and immunological effects of C. copticum and its constituents, thymol and carvacrol, were discussed in the present review. Previous studies have shown potent antiinflammatory, antioxidant, and immunological effects for C. copticum and its constituents, thymol and carvacrol. Therefore, the plant and its constituents have therapeutic values in several inflammatory and immunological disorders as well as in the oxidative stress conditions. Copyright © 2014 John Wiley & Sons, Ltd.     

党参的本草考证及药理作用和质量控制的研究进展

通过查阅文献资料,对党参进行了本草考证,药理研究及党参质量研究做了阐述与总结,为党参的质量评价及党参现代化、标准化、国际化研究提供参考依据。     

A comprehensive review on ethnomedicine,phytochemistry, pharmacology,and toxicity of Tephrosia purpurea (L.) Pers.

Tephrosia purpurea (L.) Pers. is a well‐known plant in Ayurveda and named “Sarwa wranvishapaka” for its property to heal wounds. Traditionally, it is practiced for impotency, asthma, dyspepsia, hemorrhoids, syphilis gonorrhea, rheumatism, enlargement of kidney and spleen. It is an important component of herbal preparations like Tephroli and Yakrifti used to cure liver disorders. Various phytocompounds including pongamol, purpurin, purpurenone, tephrosin, bulnesol, tephrostachin, β‐sitosterol, and so on have been reported. Modern pharmacological studies have shown that the plant have wound healing, antileishmanial, anticarcinogenic, antimicrobial, antioxidant, hepatoprotective, antifertility, antispermatogenic, anti‐diarrheal, diuretic, and insecticidal properties. Acetylcholinesterase inhibitory action reported from this plant aids its utilization for the development of drugs for Alzheimer's and dementia neurological disorders. Among the known active compounds of T. purpurea, tephrostachin is responsible for antiplasmodial activity, tephrosin, pongaglabol, and semiglabrin exerts antiulcer activity while quercetin, rutin, β‐sitosterol, and lupeol are mainly responsible for its anti‐inflammatory and anti‐cancer properties. From different toxicological studies, concentrations up to 2,000 mg/kg were considered safe. The present review comprehensively summarizes the ethnomedicine, phytochemistry, pharmacology, and toxicology of T. purpurea. Further research on elucidation of the structure–function relationship among active compounds, understanding of multi‐target network pharmacology and clinical applications will intensify its therapeutic potential.     

仝小林运用黄芪、熟地黄、黄精气血精阴并补经验

气血精阴亏虚是多种慢性疾病发展至后期的共同病机。仝小林院士临床辨治具有此类病机的疾病时,首先横向把握疾病发展的全过程,明确气血精阴亏虚出现的先后次序和相互联系,而后纵向辨别刻下气血精阴的病机主次。结合不同疾病背景和病情程度,灵活加减,精确施量。临床常以黄芪、熟地黄、黄精三药组"四补三黄方",黄芪长于益气,兼具补血之效,用量多在30~120 g;熟地黄功在养血补血,但亦可补肾填精,用量多在15~60 g;黄精以养阴补精为主,但其归于肺脾肾三经,同样可益气补血,用量多在30~60 g。三药各有侧重,又相互兼顾,相互配伍,协同发挥气血精阴并补之功效。     

HPLC同时测定虎杖及其提取物中4种有效成分的含量

目的：建立同时测定虎杖及其提取物中白藜芦、大黄素、大黄酚、大黄素甲醚4种有效成分含量的高效液相色谱法。方法：Hypersil C18色谱柱（4.6 mm×200 mm,5 μm）,流动相为乙腈和1% HAc水溶液,梯度洗脱,流速1 mL·min^-1,检测波长287 nm。 结果: 方法的平均回收率及RSD分别为：白藜芦醇101.8%,1.7%;大黄素96.2%,1.4%;大黄酚99.7%,1.0%;大黄素甲醚98.6%,0.97%。结论： 该方法可用于虎杖药材及其提取物的质量控制。