黄春林教授分型治疗IgA肾病的中医用药经验

IgA 肾病是我国最常见的原发性肾小球疾病,现无特效治疗方法,现代医学一般根据不同临床分型,采取相应治疗方法,黄春林教授借鉴现代医学分型治疗IgA 肾病的方法,结合自身经验,提出了相应的中医用药经验,具有一定的临床指导意义。     

IgA肾病中医分型的研究进展

目的:探讨IgA肾病中医分型的研究进展.方法:通过分析、概括近年来研究、治疗IgA肾病的相关文献,从病理表现辅助中医辨证分型的研究、临床证候与中医的辨证分型相结合、从治疗效果看中医辨证分型3个方面进行阐述.结论:IgA肾病辨证分型多缺乏统一的标准,应形成统一的辨证思维模式.     

脾肾相关理论在IgA肾病中的临床应用

目的：总结李顺民教授治疗IgA肾病的辨证思路和临证经验。方法：以重视脾肾相关理论为纲,结合病因病机、分型辨证治疗、多靶点理论、饮食调摄为目,从不同角度总结和剖析了李教授的对IgA肾病的理解和治疗经验。结论李顺民教授重视脾肾相关理论的临证思路在IgA肾病的治疗中具有独创性、可行性和实用性,值得我们学习和深入研究。     

活血化瘀法治疗不同病理分型IgA肾病疗效观察

目的:观察活血化瘀法治疗不同病理分型IgA肾病的疗效。方法:40例IgA肾病患者,经过肾活检确诊为IgA肾病,均给予活血化瘀法中药复肾汤治疗,观察不同病理分型患者的尿蛋白定量、尿红细胞计数及临床疗效。结果:完全缓解14例,基本缓解8例,好转12例,无效6例。总有效率85%。各病理分型均有良好的疗效,病理分型为Ⅰ、Ⅱ级的患者疗效显著,总有效率均为100%,病理分型为Ⅲ、Ⅳ级的患者总有效率分别为83.3%、60.0%。提示病理分型对IgA肾病临床疗效有一定影响,病理分型越差者,治疗效果相应降低。治疗后各病理分型患者尿蛋白定量及尿红细胞计数均有不同程度的好转(P<0.05),甚至消失,不同病理分型的结果有所不同。再次提示不同病理分型疗效有一定差异。结论:活血化瘀治疗IgA肾病疗效显著,但不同病理分型治疗效果有一定差异。     

中医辨证治疗单纯血尿性IgA肾病43例

目的:探索单纯血尿性IgA肾病的中医辨证临床分型特点。方法:观察以大火草为主的中药基本方对43例IgA肾病血尿为主的肾疾病疗效。结果:治疗后尿红细胞有显著改善,总有效率89.7%。结论:中医药辨证分型治疗单纯血尿性IgA肾病有一定疗效。     

辨证分型治疗IgA肾病92例疗效观察

目的:观察辨证分型治疗IgA肾病的临床疗效。方法:将92例患者依据其肾穿病理结果和临床表现,分为气阴两虚、脉络瘀阻型,脾肾气虚、湿浊内留型,肾气亏虚、三焦疏泄不利型进行辨证治疗。结果:完全缓解30例,基本缓解37例,有效17例,无效8例,总有效率为91.30%。结论:辨证分型治疗IgA肾病疗效可靠。     

IgA肾病的中医辨证研究 --附108例临床资料分析

IgA肾病是我国最常见的原发性肾小球疾病,由于发病机理不明,迄今现代医学仍缺乏特异性治疗,故人们寄希望于中医药。为此,我们开展了IgA肾病的中医辨证研究,旨在寻求IgA肾病的中医辨证规律,从而为中医药治疗IgA肾病提供依据。现将经肾穿刺活检确诊的108例IgA肾病的临床病理资料整理报道如下。     

杜雨茂教授治疗IgA肾病的经验

IgA肾病是一免疫病理学诊断名称。文章总结了杜雨茂教授从中医角度对IgA肾病病因、病机的认识，以及辨证用药的经验。经多年临床观察运用本治法及经验治疗IgA肾病Ⅰ至Ⅴ级均有肯定疗效，对并发肾功能不全者亦有改善。     

翟文生教授治疗免疫球蛋白A沉积性肾病（IgA nephropathy）的经验

目的：总结翟文生教授治疗原发性免疫球蛋白A沉积性肾病（IgA nephropathy）临床经验。方法：探讨该病的病因病机,提出热、瘀、虚是IgA肾病病机、辨证论治的关键;重视清热解毒利咽、活血化瘀、扶正补虚在治疗中的作用。结果与结论：翟文生教授治疗IgA肾病的经验对临床有重要的指导意义。     

IgA肾病的中医药治疗进展

IgA肾病(IgAN)是一组不伴有系统性疾病,肾活检免疫病理检查在肾小球系膜区有以IgA为主的颗粒样沉积,临床上以血尿为主要表现的肾小球肾炎,是我国主要的肾小球疾病之一,也是导致终末期肾功能衰竭的一个最主要原因.中医药治疗IgA肾病具有一定的优势.从IgA肾病临床证候特点来看,可归属于中医学“尿血”、“腰痛”、“水肿”、“虚劳”等范畴,易反复发作,缠绵难愈,好发于本虚之体.本病以脾肾虚为本;湿、热为标,瘀血内结贯穿始终,为本虚标实之证.中医药对IgA肾病的治疗多分为分型分期治疗、守方治疗和中药注射剂治疗.     

微波消解-电感耦合等离子体质谱法测定脉络宁注射液中25种矿物质元素

目的建立微波消解-电感耦合等离子体质谱(ICP-MS)直接稀释测定脉络宁注射液中25种矿物质元素(Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V、As、Cd和Hg)的方法。方法分别对微波消解条件和测试条件进行考察;样品经微波消解后,采用电感耦合质谱仪测定25种矿物质元素,并对测定方法学进行考察。结果确定最佳消解条件为3步缓慢升温:400 W 80℃升温10 min,保留5 min;600 W 120℃升温10 min,保留5 min;900 W 200℃升温20 min,保留20 min;25种矿物质元素在各自的线性范围内线性关系良好,r≥0.999 6,精密度、稳定性和重复性试验的RSD均符合定量分析要求;加标回收率为94.7%~106.1%,RSD在0.34%~2.79%。脉络宁注射液中检测出Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V,未检出As、Cd和Hg。结论该方法简便、迅速、准确,适用于脉络宁注射液中25种矿物质元素的同时测定。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

基于ICP-MS法的加味左金丸中无机元素分析

目的 通过电感耦合等离子体质谱（inductively coupled plasma mass spectrometry,ICP-MS）法建立加味左金丸中Cd、Pb、As、Hg、Co、V、Ni、Cu、Li、Sb、Ba、Mo、Sn、Cr、Na、Mg、Al、Ca、Ti、Mn、Fe、Zn、Ga、Se、Sr、Tl共计26种无机元素的测定方法。方法 加味左金丸通过微波消解法处理后,根据相对分子质量的大小选择内标物,其中⁷Li、²³Na、²⁴Mg、²⁷Al、⁴⁰Ca、⁴⁸Ti、⁵¹V、⁵²Cr、⁵⁵Mn、⁵⁶Fe、⁵⁸Ni、⁵⁹Co、⁶³Cu、⁶⁶Zn、⁷⁰Ga、⁷⁵As、⁷⁷Se、⁸⁶Sr以⁷²Ge作为内标;⁹⁵Mo、¹¹⁴Cd、¹¹⁸Sn、¹²¹Sb、¹³⁷Ba以¹¹⁵In作为内标;²⁰²Hg、²⁰⁵Tl、²⁰⁸Pb以²⁰⁹Bi作为内标。对标准品溶液、空白溶液与供试品溶液进行分析,采用标准曲线法进行定量分析。通过ICP-MS法进行测定。结果 26种无机元素线性的相关系数r ≥ 0.999 6,检出限为0.001~1.500μg/L,定量限为0.01~5.00 μg/L,精密度与重复性试验的RSD均小于5%,平均回收率在82.64%~106.44%,RSD均小于5%。对3个厂家的12批样品进行了测定,26种元素的含量差异较大,其中Na、Mg、Ca、Fe 4种元素的含量比较高,均大于500 μg/g,Cd、Pb、As、Hg、Co、Li、Sb、Mo、Sn、Cr、Se、Tl的含量比较低,均小于1 μg/g。由结果可知,人体的常量元素,如Na、Mg、Ca的含量比较高,Cd、Pb、As、Hg等有害元素含量比较低。根据《中国药典》2020年版一部的要求,本品中Cd、Pb、As、Hg与Cu均符合规定。结论 该方法快速、准确,可以用于加味左金丸中无机元素的测定。     

Erstaunliches Ergebnis einer Schädelakupunktur nach Yamamoto bei Hemihypsarrhythmie rechts

A girl, three and a half years old at the respective date, premature in 25th week of gestation, had been presented. On day three after birth, she had had a IVH III° right and left with severe involvement of parenchyma and other multiple complications, e. a. infant respiratory distress syndrome up to the 42nd day postpartum, and epileptic attacks with apnoeic events.     

Journal of Acupuncture and Tuina Science Instructions for Authors

The Journal of Acupuncture and Tuina Science, a journal with an international scope （IS SN 1672-3597, CN 31-1908/R, Bimonthly）, is embodied by ＇Springer Verlag＇ Database, Index Copernicus （IC） and Chinese Scientific and Technical Paper and Citations Data （CSTPCD）. You can search full text on http：//www, springerlink, com/content/1672 -3597.     

Yerba Mate or Paraguay Tea

正Beverages based on Ilex paraguariensis A.St.-Hil.are used in the south Brazil and other Latin American countries located at the so-called southern cone.It is known as chimarro or mate in south and southeast Brazil,tererêin     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

七味红花殊胜散对缺血再灌注肝损伤的保护作用

目的::研究七味红花殊胜敬对缺血再灌注肝损伤的保护作用.方法:在大鼠肝缺血再灌注模型上,观察七味红花殊胜散对缺血再灌注肝损伤引起的血清丙二醛(MDA)、超氧化物歧化酶(SOD)、谷胱甘肽过氧化物酶(GSH-Px)、一氧化氮(NO)含量的变化.结果:七味红花殊胜散对大鼠血清MDA、SOD、GSH与再灌组比较有明显差异(P<0.05),NO含量与再灌组比较有明显差异(P<0.05).结论:七味红花殊胜散对大鼠急性缺血再灌注肝损伤具有保护作用.     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.