基于“冬病夏治”论穴位贴敷结合小儿推拿治疗小儿慢性咳嗽

目的:观察、比较穴位贴敷法、小儿推拿法及两者结合法治疗小儿慢性咳嗽疗效差异,为小儿慢性咳嗽的治疗提供参考。方法:90例小儿慢性咳嗽患者随机分为穴位贴敷组、小儿推拿组、两者结合组,每组30例。穴位贴敷组选用辽宁中医药大学第一附属医院的"伏九贴膏"在每年的三伏进行穴位贴敷,每10天1次,3次为1个疗程;小儿推拿组通过选取肺经、肝经、内八卦、膻中等进行穴位按摩,每天1次,连续10 d为1个疗程,两者结合组采用"伏九贴膏"与小儿推拿的结合方法,操作次数与疗程和另两组相同。通过回访观测证候量表分数的变化,从而比较单纯及结合疗法的不同疗效。结果:穴位贴敷组、小儿推拿组和两者结合组的总有效率分别为90.0%、86.7%和93.3%,治疗后3组证候积分比较,差异具有统计学意义(P0.05)。结论:穴位贴敷疗法、小儿推拿疗法及两者结合法对小儿慢性咳嗽均具有良好的治疗效果,但两者结合效果更为显著,安全有效适宜推广。     

针刺四缝穴联合中药穴位贴敷辅助治疗小儿疳证的可行性分析

目的:研究针刺四缝穴配合中药穴位贴敷联合越鞠丸加减方治疗小儿疳证的效果。方法:将我院收治的60例小儿疳证患者随机分为观察组和对照组各30例,对照组给予越鞠丸加减方口服治疗,观察组在此基础上给予针刺四缝穴配合中药穴位贴敷治疗,所有患儿治疗时间均为4wk,比较两组治疗前后临床症状及体征积分和治疗总有效率。结果:两组治疗后临床症状及体征积分均较治疗前显著降低(P0.01),观察组治疗后各症状及体征积分均显著低于对照组(P0.01);观察组治疗总有效率83.3%显著高于对照组治疗总有效率60.0%(P0.05)。结论:针刺四缝穴配合中药穴位贴敷联合越鞠丸加减方可显著提高小儿疳证的治疗效果,值得临床推广。     

板门穴联合四缝穴点刺治疗小儿功能性消化不良的临床观察

目的明确板门穴联合四缝穴点刺治疗小儿功能性消化不良的临床疗效。方法将90例小儿功能性消化不良患者随机分为对照组、观察组,每组45例。对照组给予常规治疗;观察组给予四缝穴联合板门穴点刺治疗,两组均治疗4周。分别于治疗前、治疗后、随访2周、随访4周评价小儿疳证证候积分,于治疗前、治疗后检测血清中肿瘤坏死因子-α(TNF-α)、白细胞介素-10(IL-10)、胃动素(MTL)的表达,并进行临床疗效评定。结果治疗后两组小儿疳证证候积分及均较治疗前有明显改善(P 0.01),且观察组优于对照组(P 0.01);两组随访2周时积分均优于本组治疗后(P 0.05),且观察组优于对照组(P 0.01);两组随访4周时积分与本组随访2周时积分无明显差异,但观察组随访4周时积分优于对照组(P 0.01)。治疗后两组TNF-α、IL-10、MTL水平均较治疗前有明显改善(P 0.01),且观察组优于对照组(P 0.01)。对照组总有效率为77.7%,治疗组总有效率为93.3%,卡方统计显示两组有效率存在显著统计学差异,观察组优于对照组(P 0.05)。结论本研究发现四缝穴联合板门穴点刺治疗小儿功能性消化不良,可明显降低小儿疳证证候积分,调节炎症因子及胃肠激素表达,值得临床推广应用。     

隐形针灸片穴位贴敷治疗小儿食积的临床疗效观察

目的观察隐形针灸片穴位贴敷治疗小儿食积症的临床疗效。比较隐形针灸片穴位贴敷与针刺四缝两种治疗方法的临床效果。方法选取2014年6月~2015年6月本院收治的60例小儿积食患者为研究对象,并按随机数字表法随机分为对照组和观察组,每组30例。对照组给予针刺四缝穴,观察组患者予隐形针灸片穴位贴敷治疗,比较两组治疗后的疗效。结果治疗组总有效率为96.7%,对照组为90.0%,两组比较差异有统计学意义(P0.05)。结论隐形针灸是一种治疗小儿食积症的有效方法,具有操作简便、价廉、安全、无创痛等优点,值得临床普及推广应用。     

麻杏石甘汤(农本方)合穴位贴敷治疗小儿外感咳嗽的临床研究

目的观察麻杏石甘汤合穴位贴敷治疗小儿外感咳嗽的临床疗效。方法将100例患儿随机分为观察组40例、中药对照组和西药对照组各30例,观察组采用中药麻杏石甘汤加味口服,外加中药(咳喘膏)贴敷天突、肺俞穴。中药对照组予相同中药口服,不予中药外敷。西药对照组予小儿氨酚黄那敏、利巴韦林颗粒、氨溴特罗溶液口服,治疗6 d,比较各组临床症状与阳性体征消失时间,证候疗效。结果观察组在症状与体征消失时间优于中药对照组和西药对照组(P0.05)。而两对照组组间比较,差异无统计学意义(P0.05)。中医证候疗效总有效率观察组为92.11%,西药对照组为76.67%,中药对照组为68.97%,观察组分别与中药对照组和西药对照组比较,差异均具有统计学意义(P0.05)。结论麻杏石汤合穴位贴敷治疗小儿外感咳嗽疗效肯定,简便易行。     

点刺四缝穴与捏脊疗法治疗疳证疗效对照研究

目的比较点刺四缝穴法、捏脊法、点刺四缝穴配合捏脊法治疗疳证的疗效差异。方法采取简单随机方法,将96例患者分为点刺组(32例)、捏脊组(32例)、联合组(32例)。治疗1个月为1个疗程。3组患者分别于治疗前和治疗1个疗程后采用症候积分量表评分,结合中医症状疗效标准评定疗效。结果各组治疗后症状总积分皆较治疗前明显低(P0.01),提示3组均有效;3组治疗后症状总积分经方差分析两两比较,联合组治疗后症状总积分较点刺组、捏脊组降低(P0.05)。3组治疗方案对患者体重、身高的改善均无统计学差异(P0.05);而对于食欲、精神、睡眠、多汗、感染、大便失调、腹胀、头发光泽度症状均有明显改善,差异有统计学意义(P0.01)。点刺组愈显率为51.6%,捏脊组为48.4%,联合组为77.4%;联合组与点刺组、捏脊组经两两比较临床疗效差异有统计学意义(P0.05),说明联合组临床疗效优于点刺组及捏脊组。结论点刺四缝穴、捏脊及二者联合3种治疗方案均能明显改善疳证的临床症状,二者联合法的临床疗效明显优于单纯采用点刺四缝穴法和捏脊法。     

中药穴位贴敷治疗痰湿蕴肺型慢性咳嗽疗效观察

目的:观察穴位贴敷治疗痰湿蕴肺慢性咳嗽的疗效及价值。方法:将从2016年2月至2017年2月年来我院治疗的慢性咳嗽患者60例随机分为对照组和试验组,各30例,对照组患者采用常规药物方案治疗,试验组患者则在常规药物基础上,予中药穴位贴敷治疗。2组均以治疗10天为1个疗程。对比分析2组患者治疗前后主要临床症状以及体征、中医证候等指标。结果:治疗后,在疾病疗效以及中医证候疗效方面,治疗组明显优于对照组,P0.05或P0.01。结论:中药穴位贴敷治疗可明显提高常规药物口服治疗痰湿蕴肺慢性咳嗽的临床疗效。     

中西医结合治疗冠心病心绞痛56例

目的 观察中药穴位贴敷治疗冠心病心绞痛疗效。方法 将56例患者随机分为对照组与治疗组,两组均予常规治疗,治疗组加用中药穴位贴敷,疗程均为2周。观察治疗前后患者临床症状、体征,中医证候积分及心电图的改善情况。结果 中医证候疗效两组总有效率分别为92.9%和82.1%,有显著差异（P〈0.05）;心电图疗效两组总有效率分别为75.0%和71.4%,无显著差异（P〉0.05）。结论 加用中药穴位贴敷治疗冠心病心绞痛患者比单纯常规治疗,在改善症状及中医证候方面,疗效更佳。     

温中散穴位贴敷联合双歧杆菌四联活菌片、蒙脱石散口服治疗小儿风寒泻的临床观察

目的:观察温中散穴位贴敷联合双歧杆菌四联活菌片、蒙脱石散口服治疗小儿风寒泻的临床疗效。方法:将90例风寒泻患儿随机分成对照组和观察组,每组45例。对照组给予双歧杆菌四联活菌片、蒙脱石散口服治疗,观察组在对照组治疗基础上给予温中散穴位贴敷治疗。比较两组临床疗效、腹泻恢复正常时间、不良反应发生情况及治疗前后中医证候积分变化情况。结果:治疗前,两组中医证候积分比较,差异无统计学意义(P>0.05)。治疗后,两组中医证候积分均低于治疗前,且观察组低于对照组,差异均有统计学意义(P<0.05)。观察组腹泻恢复正常时间为(2.22±0.32)d,显著短于对照组的(3.41±0.61)d,差异具有统计学意义(P<0.05)。观察组治疗总有效率为95.6%(43/45),明显高于对照组的82.2%(37/45),差异具有统计学意义(P<0.05)。两组均未出现不良反应。结论:温中散穴位贴敷治疗小儿风寒泻临床疗效显著,值得临床推广。     

子午流注纳支法穴位贴敷治疗老年性骨质疏松症:随机对照研究

目的:比较子午流注纳支法穴位贴敷与传统穴位贴敷治疗老年性骨质疏松症(SOP)的临床疗效差异。方法:将76例肝肾不足证SOP患者随机分为观察组和对照组各38例。两组患者均在接受口服钙尔奇D治疗的基础上,观察组根据子午流注纳支法选穴和取穴原则选取阴谷、太溪、大钟、复溜、至阴进行按时穴位贴敷,对照组对所选取的穴位进行非按时穴位贴敷,即传统穴位敷贴,均每次贴敷6h,每天1次,连续5d后休息2d,4周为一疗程,共2个疗程。于干预前、干预4周后、干预8周后采用视觉模拟评分法(VAS)和简体中文版Oswestry功能障碍指数(ODI)问卷表分别评价患者疼痛和功能障碍情况,于干预前、干预8周后采用骨质疏松症症状评定量表和骨质疏松症生活质量调查问卷表(QUALEFFO-41)分别评价中医证候和生活质量,通过中医证候的改善情况进行临床疗效评估。结果:干预后两组患者各项观察指标均显著改善(P0.01,P0.05)。观察组干预4周后、8周后VAS和ODI均低于同期对照组(均Ρ0.05);VAS和ODI在组间效应、时间效应、两者交互作用均有统计学意义(均Ρ0.01),进一步两两比较显示,VAS和ODI后一时间点得分均低于前一时间点(均Ρ0.01)。观察组干预后QUALEFFO-41和中医证候评分均低于对照组(均Ρ0.05)。观察组总有效率为85.7%(30/35),优于对照组的74.3%(26/35,P0.05)。结论:子午流注纳支法穴位贴敷治疗肝肾不足型SOP患者在改善疼痛、功能障碍、中医证候、生活质量方面优于传统穴位贴敷,临床疗效显著。     

微波消解-电感耦合等离子体质谱法测定脉络宁注射液中25种矿物质元素

目的建立微波消解-电感耦合等离子体质谱(ICP-MS)直接稀释测定脉络宁注射液中25种矿物质元素(Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V、As、Cd和Hg)的方法。方法分别对微波消解条件和测试条件进行考察;样品经微波消解后,采用电感耦合质谱仪测定25种矿物质元素,并对测定方法学进行考察。结果确定最佳消解条件为3步缓慢升温:400 W 80℃升温10 min,保留5 min;600 W 120℃升温10 min,保留5 min;900 W 200℃升温20 min,保留20 min;25种矿物质元素在各自的线性范围内线性关系良好,r≥0.999 6,精密度、稳定性和重复性试验的RSD均符合定量分析要求;加标回收率为94.7%~106.1%,RSD在0.34%~2.79%。脉络宁注射液中检测出Mg、Ca、Fe、Cu、Zn、Mn、Al、B、Ba、Co、Cr、K、Li、Mo、Na、Ni、P、Pb、Sr、Th、Ti、V,未检出As、Cd和Hg。结论该方法简便、迅速、准确,适用于脉络宁注射液中25种矿物质元素的同时测定。     

Die Lateralität und Lateralitätsinstabilität in der Diagnostik und Therapie

The disturbance and instability of laterality are obstacles to diagnostics and therapy. Correction prior to starting therapy is required. They also predispose toward defined health problems and unspecific diseases. Numerous research activities provide evidence of the relevance of undisturbed laterality in diagnostics and therapy. Techniques of testing and therapeutic corrections will allow for optimized therapy success.     

Yerba Mate or Paraguay Tea

正Beverages based on Ilex paraguariensis A.St.-Hil.are used in the south Brazil and other Latin American countries located at the so-called southern cone.It is known as chimarro or mate in south and southeast Brazil,tererêin     

Journal of Acupuncture and Tuina Science Instructions for Authors

The Journal of Acupuncture and Tuina Science, a journal with an international scope （IS SN 1672-3597, CN 31-1908/R, Bimonthly）, is embodied by ＇Springer Verlag＇ Database, Index Copernicus （IC） and Chinese Scientific and Technical Paper and Citations Data （CSTPCD）. You can search full text on http：//www, springerlink, com/content/1672 -3597.     

Ethnopharmacologic study of chinese rhubarb

This paper deals with an interdisciplinary study covering historic, botanical, phytochemical, pharmacological and clinical aspects of rhubarb and related species, to lay stress on the correlation between plant phylogeny, chemical constituents and purgative activity.

It was found that the official rhubarbs were exclusively restricted in the Sect. Palmata e.g. Rheum palmatum R. palmatum var. tanguticum R. officinale; the following criteria may serve as their standard, viz., the presence of sennoside derivatives and rhein, the occurrence of the reduced form of rhein and aloe-emodin, the leaves with any kind of palmate incision. Comprehensive multivariate analyses showed that there is a very close relationship between the leaf incision, existence of sennosides or rhein and purgative activity.     

基于ICP-MS法的加味左金丸中无机元素分析

目的 通过电感耦合等离子体质谱（inductively coupled plasma mass spectrometry,ICP-MS）法建立加味左金丸中Cd、Pb、As、Hg、Co、V、Ni、Cu、Li、Sb、Ba、Mo、Sn、Cr、Na、Mg、Al、Ca、Ti、Mn、Fe、Zn、Ga、Se、Sr、Tl共计26种无机元素的测定方法。方法 加味左金丸通过微波消解法处理后,根据相对分子质量的大小选择内标物,其中⁷Li、²³Na、²⁴Mg、²⁷Al、⁴⁰Ca、⁴⁸Ti、⁵¹V、⁵²Cr、⁵⁵Mn、⁵⁶Fe、⁵⁸Ni、⁵⁹Co、⁶³Cu、⁶⁶Zn、⁷⁰Ga、⁷⁵As、⁷⁷Se、⁸⁶Sr以⁷²Ge作为内标;⁹⁵Mo、¹¹⁴Cd、¹¹⁸Sn、¹²¹Sb、¹³⁷Ba以¹¹⁵In作为内标;²⁰²Hg、²⁰⁵Tl、²⁰⁸Pb以²⁰⁹Bi作为内标。对标准品溶液、空白溶液与供试品溶液进行分析,采用标准曲线法进行定量分析。通过ICP-MS法进行测定。结果 26种无机元素线性的相关系数r ≥ 0.999 6,检出限为0.001~1.500μg/L,定量限为0.01~5.00 μg/L,精密度与重复性试验的RSD均小于5%,平均回收率在82.64%~106.44%,RSD均小于5%。对3个厂家的12批样品进行了测定,26种元素的含量差异较大,其中Na、Mg、Ca、Fe 4种元素的含量比较高,均大于500 μg/g,Cd、Pb、As、Hg、Co、Li、Sb、Mo、Sn、Cr、Se、Tl的含量比较低,均小于1 μg/g。由结果可知,人体的常量元素,如Na、Mg、Ca的含量比较高,Cd、Pb、As、Hg等有害元素含量比较低。根据《中国药典》2020年版一部的要求,本品中Cd、Pb、As、Hg与Cu均符合规定。结论 该方法快速、准确,可以用于加味左金丸中无机元素的测定。     

Wirksamkeit der Akupunktur bei der Therapie von idiopathischen Schmeckstörungen: Eine randomisierte Placebo-kontrollierte Studie

Background

At present, the state-of-the-art medication in treating idiopathic taste disorder (gustatory dysfunction) is zinc. If zinc medication was unsuccessful, not tolerated or if it is contraindicated the persons affected can hardly be helped.

Objectives

In a randomized placebo-controlled clinical trial an attempt was made to determine the efficacy of acupuncture.

Methods

The treatment group was treated with acupuncture needles, the placebo group with an inactive acupuncture-laser. Endpoints of the study were changes in the taste test, the quality of life and the severity of symptoms of depression (BDI) as well as mood changes (ZMS). Satisfaction with the success of the respective therapy was also evaluated. Data were collected before and after therapy and again for the treatment group 10 weeks after completion of the treatment period.

Findings

Treatment with real acupuncture showed a significant improvement in gustatory function as well as a significant improvement in psychological symptoms. Greater satisfaction with the treatment results was evident in the treatment group. The treatment results of acupuncture remained stable over a period of ten weeks after completion of the treatment.

Conclusion

Acupuncture was effective in the therapy of idiopathic taste disorders and therefore it is an effective alternative when zinc medication is not tolerated or unsuccessful. But it is also suitable as a therapy of first choice. Acupuncture can be considered as an extension of the therapeutic spectrum in the difficult treatment of taste disorders.     

Erstaunliches Ergebnis einer Schädelakupunktur nach Yamamoto bei Hemihypsarrhythmie rechts

A girl, three and a half years old at the respective date, premature in 25th week of gestation, had been presented. On day three after birth, she had had a IVH III° right and left with severe involvement of parenchyma and other multiple complications, e. a. infant respiratory distress syndrome up to the 42nd day postpartum, and epileptic attacks with apnoeic events.     

Veränderungen der Herzratenvariabilität (HRV) während Low Level Lasernadelakupunktur: Placebokontrollierte Studie an 19 herzgesunden Probanden

Background

Experimental and clinical studies postulate a neurobiological mechanism of acupuncture by modulating central pain systems, neurohormones and -transmitters. It seems to be quite likely that the autonomic nervous system (ANS) plays an important mediating role in this neuromodulation.

Aim

In measuring heart rate variability (HRV), as a non-invasive approach to the ANS-function, the object of this study was to monitor probable acupuncture-induced changes of autonomic balance. The innovative technology of laser-needle acupuncture offers for the first time a stimulation method which fulfils the demands on a placebo-controlled acupuncture trial not requiring controversial sham acupuncture.

Method

19 healthy voluntary subjects underwent 3 treatments in randomized sequence, consisting of placebo-, 1-point- (PC 6) and simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle-stimulation over 20 minutes. Before, during and after placebo-/verum laser-needle acupuncture, HRV-data for normalized HF(high frequency)- and LF(low frequency)-Power (nHF, nLF) and their quotient nLF/nHF obtained by power spectrum analysis (FFT), were measured and analyzed statistically at 5 different time points (ANOVA repeated measures, p < 0,05).

Results

During both verum applications, the 1-point- (PC 6) as well as the simultaneous 3-point- (PC 6, LR 3, SI 3) laser-needle stimulation, significant changes of the ANS-activity were found in comparison to the placebo application. The most significant modification of HRV was an increase of nHF (p < 0,05 (PC 6), p < 0,0001 (PC 6, LR 3, SI 3)) as an expression of growing vagal activity during acupuncture.

Conclusion

Laser-needle acupuncture causes in 1-point-stimulation (PC 6) as well as in simultaneous 3-point-stimulation (PC 6, LR 3, SI 3) significant changes in HRV in comparison to placebo application. HRV-monitoring seems to be a suitable approach in exploration of acupuncture-induced changes of ANS and could possibly be established in combination with laser needle acupuncture as a standard for further scientific and clinical acupuncture investigations which are greatly needed.