吻合器痔上黏膜环切术治疗重度混合痔的效果分析

目的探讨吻合器痔上黏膜环切术在重度混合痔中的应用效果。方法选取2012-06~2014-07该院收治的58例重度混合痔患者为研究对象,按照奇偶随机方法分为对照组和观察组,各29例,对照组采用传统的外剥内扎术治疗,观察组采用吻合器痔上黏膜环切术治疗,观察比较两组治疗方式的治疗效果。结果观察组的手术时间、术中出血量、住院时间、住院费用均少于对照组,组间比较差异有统计学意义(P0.01);观察组的并发症发生率为17.24%,对照组为65.52%,组间比较差异有统计学意义(P0.05)。结论吻合器痔上黏膜环切术在重度混合痔中的应用效果显著,有利于患者恢复,安全可靠,并发症少,值得在临床上推广。     

改良吻合器痔上黏膜环切术治疗重度环状混合痔58例

2009年1-11月,我们采用改良吻合器痔上黏膜环切术（PPH）治疗重度环状混合痔患者58例,效果较好。现报告如下。     

吻合器痔上黏膜环切术联合外痔切除术治疗Ⅲ、Ⅳ度混合痔80例疗效观察

目的观察吻合器痔上黏膜环切术（PPH）联合外痔切除术治疗Ⅲ、Ⅳ度混合痔的临床疗效。方法将同期收治的160例Ⅲ、Ⅳ度混合痔患者随机分为观察组和对照组各80例,观察组行PPH联合外痔切除术,对照组仅行PPH。观察两组临床疗效、手术时间、术中出血量、住院时间、术后48 h视觉模拟疼痛（VAS）评分及并发症发生情况。结果观察组痊愈率显著高于对照组,术中出血量、住院时间及术后48 h VAS评分均显著少于对照组,并发症发生率显著低于对照组（P〈0.05或0.01）。结论 PPH联合外痔切除术治疗Ⅲ、Ⅳ度混合痔疗效显著,且患者术中出血少、术后恢复较快、并发症较少。     

痔上黏膜环切钉合术与外剥内扎术对老年环状混合痔患者术后肛门功能的影响

目的探讨痔上黏膜环切钉合术(PPH)与外剥内扎术(Milligan-Morgan)对老年环状混合痔患者术后肛门功能的影响。方法 115例老年环状混合痔患者按照随机分组方法分为PPH组(59例)和Milligan-Morgan组(56例)。术前及术后3个月分别进行Wexner便秘评分、Cleveland Clinic失禁评分及肛门直肠测压。结果两组性别、年龄、病程、住院天数均无明显差异(P0.05)。Wexner便秘评分两组之间及手术前、后均无显著差异(P0.05)。Cleveland Clinic失禁评分、肛管静息压、肛管最大收缩压、肛管高压带长度术前均无显著差异(P0.05),术后Cleveland Clinic失禁评分Milligan-Morgan组较PPH组显著升高(P0.05),肛管静息压、肛管最大收缩压Milligan-Morgan组较PPH组显著下降(P0.05),肛管高压带长度Milligan-Morgan组较PPH组显著变短(P0.05)。结论与Milligan-Morgan比较,PPH治疗老年环状混合痔患者对肛门功能影响更小,具有一定优势。     

吻合器痔上黏膜环切钉合术的手术处理与并发症预防

目的探讨吻合器痔上黏膜环切钉合术（PPH）的手术处理与并发症预防。方法对该院2010—10—2012—10实施PPH手术136例患者的临床资料进行回顾性分析。结果全组有效率为93．4％,手术并发症发生率为14．7％,主要为术后出血、感染、吻合口狭窄、肛门疼痛和肛门门口感觉异常。结论PPH是治疗重度痔、直肠内脱垂的首选方法,规范的手术操作及围手术期处理是减少手术并发症的主要措施。     

吻合器痔上黏膜环切术和Milligan-Morgan痔切除术后3a疗效比较

目的比较吻合器痔上黏膜环切术（PPH术）和Milligan-Morgan痔切除术（MM术）的近远期疗效。方法回顾性分析我院2006年1～12月101例PPH术及242例MM术患者的临床资料并进行了随访,比较术后近远期疗效及并发症情况。结果近期疗效,两组治愈率无统计学差异,两组在总并发症发生率、出血、水肿、疼痛程度、疼痛时间、手术时间、住院时间及住院费用方面,差异有统计学意义（P均〈0.01）。术后3 a,PPH术组复发率高于MM术组（P〈0.05）。结论 PPH术与MM术在近远期疗效上无显著性差异,PPH术在降低近期并发症上有一定优势,但远期复发率更高。     

吻合器痔上黏膜环切术联合外剥内扎手术治疗Ⅲ-Ⅳ度环状混合痔的疗效及对患者肛门功能的影响

目的:环状混合痔对于肛门功能的损害极大,本实验旨在探究患有Ⅲ-Ⅳ度环状混合痔患者经吻合器痔上黏膜环切术联合外剥内扎手术治疗后,对自身肛门功能产生的影响,使患者受益.方法:此次试验将对2018年6月-2019年6月来我科室就诊的98例Ⅲ-Ⅳ度环状混合痔患者展开研究,由医护人员通过计算机随机数分组法分成两组,两组人数均等,...     

吻合器痔上黏膜环切术和腹腔镜悬吊手术在重度直肠黏膜脱垂治疗中的疗效对比

重度直肠黏膜脱垂严重地影响患者的日常生活质量,因此,采取有效的手术治疗十分必要〔1,2〕。吻合器痔上黏膜环切术(PPH)和腹腔镜直肠悬吊手术是临床上常见的用于治疗重度直肠黏膜脱垂的手术方式〔3〕。本研究拟分析PPH和腹腔镜直肠悬吊手术各自疗效。     

保留灌肠促进吻合器痔上黏膜环切术后创面愈合的临床观察

目的观察甲硝唑＋布比卡因混合液保留灌肠对吻合器痔上黏膜环切术后创面愈合的影响。方法回顾性分析123例行吻合器痔上黏膜环切术患者的创面愈合情况,其中53例采用甲硝唑＋布比卡因混合液保留灌肠者作为实验组,70例未行保留灌肠的患者作为对照组,比较两组术后创面出血、水肿、疼痛感、吻合口愈合情况。结果两组术后创面出血的发生率无差异（P=0．247）;实验组术后创面水肿、疼痛情况均较对照组有改善（P〈0．01）;实验组术后吻合口炎发生率低于对照组（P=0．011）。结论保留灌肠法可以有效促进吻合器痔上黏膜环切术后创面愈合,减少患者痛苦,疗效确切安全。     

透明帽辅助内镜下硬化术与吻合器痔上黏膜环切钉合术治疗内痔的临床对照研究

目的　比较透明帽辅助内镜下硬化术（cap‑assisted endoscopic sclerotherapy,CAES）与吻合器痔上黏膜环切钉合术（procedure for prolapse and hemorrhoids,PPH）治疗内痔的有效性与安全性。方法　本研究为前瞻性双盲对照临床研究。将保定市第一中心医院2018年3月—2020年3月收治的80例符合纳入且不符合排除标准的内痔患者以随机数字表法分成CAES组（n=40）和PPH组（n=40）,分别接受不同的手术方式。比较两组围手术期相关指标,包括术中出血量、手术时间、术后24 h和48 h疼痛视觉模拟量表（visual analogue scale,VAS）评分、住院时间、治疗费用、恢复正常生活时间、治愈率。比较两组术后3个月并发症情况和术后1年复发情况。结果　受试者均顺利完成手术。与PPH组相比,CAES组术中出血量［（0.54±0.15）mL比（7.32±2.17）mL］和治疗费用［（6 249.53±435.67）元比（7 832.96±526.74）元］均显著减少（t=19.714,P<0.05;t=14.650,P<0.05）,住院时间［（3.53±0.94） d比（5.18±1.36） d］和恢复正常生活时间［（5.26±1.28） d比（7.17±2.09） d］均显著缩短（t=6.312,P<0.05;t=4.929,P<0.05）。两组手术时间对比差异无统计学意义（t=0.977,P>0.05）。CAES组术后24 h［（2.64±0.70）分比（3.59±0.93）分］、48 h［（1.28±0.31）分比（2.16±0.57）分］疼痛VAS评分均显著低于同期PPH组（t=5.162,P<0.05;t=8.578,P<0.05）。CAES组和PPH组治愈率比较差异无统计学意义［90.0%（36/40）比97.5%（39/40）,χ2=0.853,P=0.356］。术后3个月随访期间,CAES组尿潴留［0.0%（0/40）比15.0%（6/40）］、疼痛发生率［2.5%（1/40）比22.5%（9/40）］均显著低于PPH组（χ2=4.504,P<0.05;χ2=7.314,P<0.05）。80例患者均无其他并发症发生。随访1年,CAES组复发率为7.5%（3/40）,与PPH组5.0%（2/40）相比,差异无统计学意义（χ2=0.180,P>0.05）。结论　CAES作为一种治疗内痔的新型微创技术具有与PPH相当的治愈率和术后1年复发率。且与PPH相比,CAES具有创伤更小、痛苦更小、康复速度更快及费用更经济等优点。     

Systematic Review on the Procedure for Prolapse and Hemorrhoids (Stapled Hemorrhoidopexy)

Purpose The procedure for prolapse and hemorrhoids (stapled hemorrhoidopexy) has been introduced as an alternative to conventional hemorrhoidectomy. This is a systematic review on stapled hemorrhoidopexy of all randomized, controlled trials that have been published until August 2006. Methods All published, randomized, controlled trials comparing stapled hemorrhoidopexy to conventional hemorrhoidectomy were identified from Ovid MEDLINE, EMBASE, CINAHL, and all Evidence-Based Medicine Reviews (Cochrane Central Register of Controlled Trial, Cochrane Database of Systemic Review, and Database of Abstracts of Reviews of Effects) between January 1991 and August 2006. Meta-analysis was performed by using the Forest plot review if feasible. Results A total of 25 randomized, controlled trials with 1,918 procedures were reviewed. The follow-up duration was from 1 to 62 months. Stapled hemorrhoidopexy was associated with less operating time (weighted mean difference, −11.35 minutes; P = 0.006), earlier return of bowel function (weighted mean difference −9.91 hours; P < 0.00001), and shorter hospital stay (weighted mean difference, −1.07 days; P = 0.0004). There was less pain after stapled hemorrhoidopexy, as evidenced by lower pain scores at rest and on defecation and 37.6 percent reduction in analgesic requirement. The stapled hemorrhoidopexy allowed a faster functional recovery with shorter time off work (weighted mean difference, −8.45 days; P < 0.00001), earlier return to normal activities (weighted mean difference, −15.85 days; P = 0.03), and better wound healing (odds ratio, 0.1; P = 0.0006). The patients’ satisfaction was significantly higher with stapled hemorrhoidopexy than conventional hemorrhoidectomy (odds ratio, 2.33; P = 0.003). Although there was increase in the recurrence of hemorrhoids at one year or more after stapled procedure (5.7 vs. 1 percent; odds ratio, 3.48; P = 0.02), the overall incidence of recurrent hemorrhoidal symptoms—early (fewer than 6 months; stapled vs. conventional: 24.8 vs. 31.7 percent; P = 0.08) or late (1 year or more) recurrence rate (stapled vs. conventional: 25.3 vs. 18.7 percent; P = 0.07)—was similar. The overall complication rate did not differ significantly from that of conventional procedure (stapled vs. conventional: 20.2 vs. 25.2 percent; P = 0.06). Compared with conventional surgery, stapled hemorrhoidopexy has less postoperative bleeding (odds ratio, 0.52; P = 0.001), wound complication (odds ratio, 0.05; P = 0.005), constipation (odds ratio, 0.45; P = 0.02), and pruritus (odds ratio, 0.19; P = 0.02). The overall need of surgical (odds ratio, 1.27; P = 0.4) and nonsurgical (odds ratio, 1.07; P = 0.82) reintervention after the two procedures was similar. Conclusions The Procedure for Prolapse and Hemorrhoid (stapled hemorrhoidopexy) is safe with many short-term benefits. The long-term results are similar to conventional procedure. Read at the meeting of The American Society of Colon and Rectal Surgeons, Seattle, Washington, June 3 to 7, 2006.     

直肠黏膜环切术治疗直肠前突30例疗效观察

目的观察直肠黏膜环切术(PPH)治疗直肠前突的临床疗效。方法将60例直肠前突患者随机分为治疗组30例,采用PPH术;对照组30例,采用经直肠切开修补术(Sehapayah法)。观察两组患者治愈率及术后并发症。结果治疗组与对照组治愈率分别为70.0%和43.3%,差异有统计学意义(P0.05)。术后排空困难、会阴膨出感的发生率治疗组低于对照组(P0.05或0.01)。结论治疗直肠前突PPH术与传统经直肠切开前突修补术相比,具有手术操作简单、术后并发症少、恢复时间短、安全性高等优点。     

Procedure for prolapse and hemorrhoids vs traditional surgery for outlet obstructive constipation

AIM: To compare the clinical efficacies of two surgical procedures for hemorrhoid rectal prolapse with outlet obstruction-induced constipation.METHODS: One hundred eight inpatients who underwent surgery for outlet obstructive constipation caused by internal rectal prolapse and circumferential hemorrhoids at the First Affiliated Hospital of Xinjiang Medical University from June 2012 to June 2013 were prospectively included in the study.The patients with rectal prolapse hemorrhoids with outlet obstructioninduced constipation were randomly divided into two groups to undergo either a procedure for prolapse and hemorrhoids(PPH)(n = 54) or conventional surgery(n = 54; control group).Short-term(operative time,postoperative hospital stay,postoperative urinary retention,postoperative perianal edema,and postoperative pain) and long-term(postoperative anal stenosis,postoperative sensory anal incontinence,postoperative recurrence,and postoperative difficulty in defecation) clinical effects were compared between the two groups.The short- and long-term efficacies of the two procedures were determined.RESULTS: In terms of short-term clinical effects,operative time and postoperative hospital stay were significantly shorter in the PPH group than in the control group(24.36 ± 5.16 min vs 44.27 ± 6.57 min,2.1 ± 1.4 d vs 3.6 ± 2.3 d,both P 0.01).The incidence of postoperative urinary retention was higher in the PPH group than in the control group,but the difference was not statistically significant(48.15% vs 37.04%).Theincidence of perianal edema was significantly lower in the PPH group(11.11% vs 42.60%,P 0.05).The visual analogue scale scores at 24 h after surgery,first defecation,and one week after surgery were significantly lower in the PPH group(2.9 ± 0.9 vs 8.3 ± 1.1,2.0 ± 0.5 vs 6.5 ± 0.8,and 1.7 ± 0.5 vs 5.0 ± 0.7,respectively,all P 0.01).With regard to long-term clinical effects,the incidence of anal stenosis was lower in the PPH group than in the control group,but the difference was not significant(1.85% vs 5.56%).The incidence of sensory anal incontinence was significantly lower in the PPH group(3.70% vs 12.96%,P 0.05).The incidences of recurrent internal rectal prolapse and difficulty in defecation were lower in the PPH group than in the control group,but the differences were not significant(11.11% vs 16.67% and 12.96% vs 24.07%,respectively).CONCLUSION: PPH is superior to the traditional surgery in the management of outlet obstructive constipation caused by internal rectal prolapse with circumferential hemorrhoids.     

PPH术与外剥内扎术治疗环形混合痔临床对比观察

目的比较吻合器痔上黏膜环形切除术（PPH）与外剥内扎术治疗环形混合痔临床效果。方法将156例环形混合痔患者随机分为A组（PPH组）和B组（对照组）各78例，分别进行吻合器痔上黏膜环切术和外剥内扎术。比较两组手术时间、创面愈合时间、住院时间及其术后疼痛指数、肛门功能、术后并发症发生情况。结果两组患者术后原有症状均得到了有效控制。手术时间、创面愈合时间、住院时间及其术后疼痛指数、肛门功能A组均优于B组。肛管压力测定A组手术前后无变化，B组术后明显降低。结论与外剥内扎术相比，PPH术安全、有效、手术时间短、住院时间短、恢复快、并发症少。     

Stapled Hemorrhoidopexy Is Associated with a Higher Long-Term Recurrence Rate of Internal Hemorrhoids Compared with Conventional Excisional Hemorrhoid Surgery

Purpose The purpose of this systematic review was to compare the long-term results of stapled hemorrhoidopexy with conventional excisional hemorrhoidectomy in patients with internal hemorrhoids. Methods A systematic review of all randomized, controlled trials comparing stapled hemorrhoidopexy and conventional hemorrhoidectomy with long-term results was performed by using the Cochrane methodology. The minimum follow-up was six months. Primary outcomes were hemorrhoid recurrence, hemorrhoid symptom recurrence, complications, and pain. Results Twelve trials were included. Follow-up varied from six months to four years. Conventional hemorrhoidectomy was more effective in preventing long-term recurrence of hemorrhoids (odds ratio (OR), 3.85; 95 percent confidence interval (CI), 1.47–10.07; P < 0.006). Conventional hemorrhoidectomy also prevents hemorrhoids in studies with follow-up of one year or more (OR, 3.6; 95 percent CI, 1.24–10.49; P < 0.02). Conventional hemorrhoidectomy is superior in preventing the symptom of prolapse (OR, 2.96; 95 percent CI, 1.33–6.58; P < 0.008). Conventional hemorrhoidectomy also is more effective at preventing prolapse in studies with follow-up of one year or more (OR, 2.68; 95 percent CI, 0.98–7.34; P < 0.05). Nonsignificant trends in favor of conventional hemorrhoidectomy were seen in the proportion of asymptomatic patients, bleeding, soiling/difficultly with hygiene/incontinence, the presence of perianal skin tags, and the need for further surgery. Nonsignificant trends in favor of stapled hemorrhoidopexy were seen in pain, pruritus ani, and symptoms of anal obstruction/stenosis. Conclusions Conventional hemorrhoidectomy is superior to stapled hemorrhoidopexy for prevention of postoperative recurrence of internal hemorrhoids. Fewer patients who received conventional hemorrhoidectomy complained of hemorrhoidal prolapse in long-term follow-up compared with stapled hemorrhoidopexy. Podium presentations at the Canadian Surgical Forum, Montreal, Quebec, Canada, September 8 to 11, 2005, and the Tripartite Colorectal Meeting, Dublin, Ireland, July 5 to 7, 2005. This paper is based on a Cochrane Review published in The Cochrane Library 2006, Issue 4. Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, The Cochrane Library should be consulted for the most recent version of the review.     

吻合器痔上黏膜环形切除术治疗内痔的研究进展

吻合器痔上黏膜环形切除术(procedure for prolapse and hemorrhoids,PPH)是根据肛垫下移学说发明.因该手术方法具有治疗效果显著,住院时间短,术后疼痛轻,愈合快,并发症少等优点,已作为一项新的外科技术广泛应用于临床治疗Ⅲ-Ⅳ度内痔.本文拟结合国内外吻合器痔上黏膜环形切除术的临床实践和对比研究,对这一手术方法的现状及发展进行综合阐述.     

改良单荷包四点牵引PPH在环状混合痔中的应用

目的比较改良单荷包四点牵引法与传统单荷包单点牵引法吻合器痔上黏膜环切术（PPH）治疗环状混合痔中的临床疗效。 方法选取2017年1月至2019年1月联勤保障部队第九〇〇医院普通外科收治的140例环状混合痔患者的临床资料,随机分成改良组和传统组,各70例,改良组采用单荷包四点牵引PPH,传统组采用单荷包单点牵引PPH。对两组临床疗效、术中情况、术后并发症及复发情况进行比较。 结果改良组与传统组治愈率分别为95.71%和82.86%,差异有统计学意义（χ²=6.048,P=0.014）。改良组切除的黏膜环的宽度（t=12.772,P<0.05）、黏膜环均匀程度（χ²=7.368,P<0.05）、痔核完全回缩（χ²=6.048,P<0.05）均优于传统组,差异有统计学意义;术后随访1年,改良组和传统组复发率分别为0.00%和7.14%,差异有统计学意义（χ²=5.185,P<0.05）;两组手术时间（t=1.081,P>0.05）和术中出血（χ²=0.085,P>0.05）差异无统计学意义;术后第1天、第7天的VAS疼痛评分差异无统计学意义（t_1d=0.731,t_7d=1.243;P>0.05）;改良组与传统组术后并发症总体发生率分别为8.57%和20%,差异无统计学意义（χ²=3.773,P>0.05）;两组住院时间差异无统计学意义（t=0.335,P>0.05）。 结论改良的单荷包四点牵引法PPH与传统单荷包单点牵引法PPH相比,术中切除的黏膜环较均匀一致,痔核回缩效果好,治愈率高,复发率低,值得临床应用。     

吻合器痔上黏膜适形切除钉合术治疗Ⅲ~Ⅳ度环状混合痔的临床疗效分析

目的观察吻合器痔上黏膜适形切除钉合术治疗Ⅲ~Ⅳ度环状混合痔的临床疗效。 方法采用回顾性队列研究方法。收集2019年1月~2020年1月在温州医科大学附属第二医院、育英儿童医院确诊并接受手术的Ⅲ~Ⅳ度环状混合痔患者,根据手术方式的不同将患者分为适形切除组和传统痔上黏膜环切术（PPH）组。回顾性分析比较两组手术相关指标、术后1年并发症等情况。 结果共有275例患者符合纳入标准,77例患者接受适形切除术,198例患者接受传统PPH术,两组在性别构成、年龄、病程及痔分度等方面差异无统计学意义。适形切除组术中失血量（Z=-6.472,P＜0.01）和术后24 h疼痛评分（t=-5.152,P＜0.01）明显低于传统PPH组,手术时间（均值35.2 vs. 31.9 min,t=-2.871;P=0.004）略长于传统PPH组。但两组住院天数（t=-0.467,P＞0.05）及住院费用（t=1.141,P＞0.05）指标差异无统计学意义。适形切除组术后总体并发症发生率明显低于传统PPH组［9.1%（7/77）vs. 35.8%（71/198）,χ²=19.55;P=0.000］,其中术后复发［2.6%（2/77）vs. 10.1%（20/198）,χ²=4.241;P=0.039］明显低于传统PPH组,中度肛门狭窄及Ⅱ度肛门失禁程度以上并发症两组比较差异无统计学意义（P＞0.05）,但轻度肛门狭窄适形切除组明显低于传统PPH组［1.3%（1/77）vs. 8.1%（16/198）,χ²=3.305;P=0.069］,I度肛门失禁适形切除组明显低于传统PPH组［0%（0/77）vs. 7.1%（14/198）,χ²=4.366;P=0.037］。术后慢性疼痛（P＞0.05）、术后出血（P＞0.05）、肛周分泌物（χ²=0.870,P＞0.05）、肛门坠胀感（χ²=0.010,P＞0.05）在两组间差异无统计学意义（P＞0.05）。适形切除组无术后出血、术后慢性疼痛及肛门失禁的并发症发生。 结论吻合器痔上黏膜适形切除钉合术可安全有效地用于Ⅲ~Ⅳ度环状混合痔的治疗,具有较轻的术后疼痛,较低的术后并发症和复发率,值得临床推广应用。     

改良PPH术治疗老年重度痔46例临床分析

目的 应用改良吻合器痔上黏膜环切术(PPH术)治疗老年重度痔,观察疗效,总结临床经验.方法 回顾分析我科2007年6月至2009年6月期间应用改良PPH术治疗以肿块脱出及便血为主要症状的46例老年Ⅲ、Ⅳ期痔患者的临床资料和随访结果. 结果 改良PPH术创伤小、疼痛轻、恢复快,且对控制出血、防止脱垂以及减少并发症的作用显著,患者满意度达97.3%. 结论 改良PPH术治疗老年重度痔疗效确切、并发症少、术后恢复快,切实可行.