What counselling to give to workers occupationally exposed to asbestos?

When one approaches the issue of the follow-up of workers occupationally exposed to asbestos the first question to resolve is "what counselling to give?" This constitutes an essential first step because it allows people to decide whether or not they wish to accept the proposed follow up programme. The difficulty relates to the idea of exposure to a carcinogen. Facing this question is never easy and generates emotional responses that cannot be ignored. Therefore the content should include elements that allow an understanding of the diseased concerned, the risk (depending on the type of exposure), the benefits and limits of screening, and an awareness of the possible consequences of follow up. The programme should allow enough time for one to one discussion with a professional to consider all aspects. It may be necessary to meet for a second time. This counselling may be given, to subjects over 50 years old, in the framework of either the occupational health or social security services. The counselling of people exposed to asbestos justifies, in itself, a follow up programme and represents its main benefit. It should guarantee the worker's most elementary right: to decide for himself in full knowledge of the facts.     

Management of severe acute to fulminant hepatitis B: to treat or not to treat or when to treat?

Despite a decline in cases of acute hepatitis B and the low hepatitis B virus (HBV) chronicity rates in adults, still some patients progress to HBV-related fulminant liver failure. In this review, we discuss treatment options that may prevent the progression of severe acute hepatitis B to fulminant liver failure and death. In severe acute HBV with prolonged prothrombin time and increased bilirubin, interferon failed to be effective while antiviral treatment, particularly with lamivudine, appears to improve survival (mean survival almost 80%). Outcome without antiviral therapy has remained considerably poor, whereas there is no convincing evidence of amelioration of HBV-targeted immunity. Of note, most patients who died or required transplantation despite lamivudine therapy, were started on lamivudine at advanced stages compared with those survived. This suggests that prompt and timely antiviral therapy is crucial. Owing to the abovementioned results the design of randomized placebo-control trials in the setting of severe acute hepatitis B seems unethical. On the contrary, the design of multicentre double-blind randomized trials to compare the efficacy between lamivudine and entecavir or even tenofovir in acute severe HBV cases is ideally needed, but these studies appear to be very difficult to perform considering that these cases are not frequent and therefore, it is almost impossible to have two arms adequately numerous and homogenous for statistical evaluation. Thus, in the absence of solid evidence based data, the hepatologists could treat their patients with severe acute hepatitis B with lamivudine or the most potent antivirals entecavir or tenofovir.     

Instructions to Authors

The Chinese Journal of Parasitology and Parasitic Diseases （CJPPD） is an academic journal of the China Preventive Medicine Association and published bimonthly by the National Institute of Parasitic Diseases, Chinese Center for Disease Control and Prevention （China CDC）. CJPPD publishes original papers from all areas of human parasitology and parasitic diseases. CJPPD has been listed in Index.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month. Original Research, Clinical Trials, Reviews, Comments, and Case Reports in esophageal cancer, gastric cancer, colon cancer, liver cancer, viral liver diseases, etc., from all over the world are welcome on the condition that they have not been published previous…     

Instructions to authors

GENERAL INFORMATIONWorld Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month.Original Research, Clinical Trials, Reviews, Comments, and Case     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327CN 14-1219/R)     

Instructions to authors

GENERAL INFORMATIONWorld Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month. Original Research, Clinical Trials…     

Instructions to authors

GENERAL INFORMATIONWorld Jornal of Gastroenterology(WJG,World J gastroenterology ISSN 1007-9327 CN14-1219/R)is a weekly journal of more than 48 000 circulation,published onthe 7~(th),14~(th),21~(st)and 28~(th)of every month.Original Research,Clinical Trials,Reviews,Comments,and Case Reportsin esophageal cancer,gastric cancer,colon cancer,liver cancer,viral liverdiseases,etc.,from all over the world are welcome on the condition thatthey have not been published previously and have not been submittedsimultaneouslv elsewhere.     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month. Original Research, Clinical Trial…     

Instructions to authors

GENERAL INFORMATIONWorld Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327/ CN 14-1219/R) is a weekly journal of with a circulation of more than 15 707, published on the 7th, 14th, 21st and 28th of every month. WJG is a peer-reviewed journal. The number of overseas users with an independent IP address was 15 600, representing 123 countries worldwide. Original research, reviews, comments, and     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, World J Gastroenterol ISSN 1007-9327/ CN 14-1219/R) is a weekly journal with a circulation of more than 15 707, published on the 7th, 14th, 21st and 28th of every month. WJG is a peer-reviewed journal. In 2007 the number of     

Instructions to authors

GENERAL INFORMATION World Journal of Gastroenterology (WJG, ISSN 1007-9327 CN 14-1219/R) is a weekly journal of more than 48 000 circulation, published on the 7th, 14th, 21st and 28th of every month. Original Research, Clinical Trials, Reviews, Comments, and Case