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1.
中医学认为重症急性胰腺炎(SAP)为腑气不通、热毒内蕴、血流淤阻所致.治法以理气通腑和通里攻下、清热解毒为主.大黄单剂及复方制剂清胰汤、大承气汤等对SAP疗效已获公认[1-2].本研究应用自拟的清胰活血汤治疗急性坏死性胰腺炎( ANP)并多器官功能不全(MODS)大鼠,观察其对腹腔内压增高的疗效,为临床治疗奠定实验基础.  相似文献   

2.
目的探索中医药治疗2型糖尿病(T2DM)用药规律。方法选择2012年10月—2015年10月中医治疗临床验证糖尿病取得良好疗效患者98例,从整体治疗方法当中提取糖尿病应用各类中药使用比例,频率与次数等,同时对中药治疗2型糖尿病用药规律进行分析。结果用中药对糖尿病进行治疗时,出现率最高为黄芪,接下来是茯苓,山药,天花粉,麦冬,白术,人参,山茱萸,泽泻,当归等。对2型糖尿病进行治疗一百四十多种中医药中,清热型药物用药频率是最高的,接下来为补气药,活血化瘀,补阴及利水渗湿的药物等。选取98例中医药治疗2型糖尿病且取得良好疗效患者当中,具有显著治疗效果70例,占71.43%;所有病人治疗有效性最高的已达百分之百有效率,最低有效率是67.83%。结论中医药对2型糖尿病进行治疗主要本着清热、益气养阴为主,祛痰为辅的治疗目的,应用中医药对糖尿病进行治疗过程中,一般采取活血化瘀,清热与补虚药等几个中药类型。  相似文献   

3.
目的通过该次研究分析中药治疗糖尿病的用药规律以及中药治疗糖尿病的临床疗效。方法选取2016年12月—2017年12月该院收治的糖尿病患者共计98例作为该次研究的对象,对98例糖尿病患者的临床资料进行回顾性分析,探究糖尿病治疗的中医疗法的用药规律以及给予中医药治疗方法治疗之后的临床效果。将98例患者按照治疗方法分为两组,每组49例患者,实验组患者给予中医治疗糖尿病的方法对糖尿病进行干预,对照组患者采用常规糖尿病治疗的方法进行血糖控制。结果该次研究的98例患者当中,中药治疗糖尿病应用的主要中药种类为:黄芪、生地、山药、天花粉、麦冬,主要应用的剂型以清热类为主,补气类和活血类也较为常用,中药治疗糖尿病的总有效率在87.75%左右,未发现不良发生。对照组患者采用传统的西药对糖尿病进行控制,主要有:胰岛素注射、二甲双胍、拜糖平等药物治疗,患者的治疗有效率约为57.14%。结论糖尿病患者采用中医药治疗方法的临床疗效较好,治疗的有效率比较高,主要的剂型为清热类和补气类,主要应用的中药种类有:黄芪、生地、山药、天花粉、麦冬等,这些中药对于糖尿病具有一定的治疗效果。中药的治疗效果较好,用药安全性较高,该次研究结果表明中医药对于糖尿病具有较好的治疗效果,糖尿病主要用的中药剂型为清热类和补气类,糖尿病的临床治疗当中,中药治疗具有较高的有效率,不良反应发生率较低,值得在临床糖尿病的治疗和干预工作当中广泛推广和应用。  相似文献   

4.
目的对糖尿病中药复方用药规律的相关内容进行研究和分析。方法对近20年以来的临床治疗糖尿病有良好疗效的中药复方进行研究和分析,对当中的用药规律进行总结。结果在该次选择的共50首复方当中,共涉及到了95种中药,当中主要以补气、补阴和清热活血类的药物为主,使用频率比较高。结论临床上中医对于糖尿病的治疗主要以益气补血、养阴清热和活血化瘀为主要原则进行治疗,因此药物使用上也主要以益气补血、养阴清热和活血化瘀药物为主。  相似文献   

5.
急性胰腺炎(acute pancreatitis,AP)是临床上常见的急腹症之一,约20%发展为重症急性胰腺炎(severe acute pancreatitis,SAP).微循环障碍、白细胞过度活化、活性氧的大量释放、炎症因子过表达、细胞凋亡紊乱和钙超载在SAP的发展过程中起重要作用.大量文献报道中药对SAP有较好的疗效.近十年来发现大黄素与白藜芦醇在治疗SAP动物模型研究十分活跃.本综述旨在归纳大黄素、白藜芦醇治疗SAP实验研究的作用机制,通过从传统中药学及现代药理学角度对比分析二者在治疗SAP作用及机制的异同点,为临床开发新的治疗SAP的中药复方注射液提供新的思路.  相似文献   

6.
[目的]探讨复方大黄对急性重症胰腺炎(SAP)继发感染治疗中血清内毒素及白细胞介素8(IL-8)水平的影响.[方法]对入选的SAP患者,分别应用中药复方大黄治疗(治疗组)、33%硫酸镁治疗(对照组),并在临床表现、血清内毒素及IL-8水平等方面进行对比观察.[结果]治疗组治疗1周及2周后血清内毒素和IL-8水平降低均明显优于对照组(P<0.05,<0.01).[结论]早期应用复方大黄能使SAP患者血清内毒素水平明显降低,一定程度上抑制了促炎细胞因子IL-8.  相似文献   

7.
目的 评价全胃肠外营养(TPN)和肠内营养(EN)联合应用对重症急性胰腺炎(SAP)的治疗效果,明确全胃肠外营养与肠内营养在重症急性胰腺炎中的作用.方法 采用前瞻性、对照、开放式临床研究,将确诊为重症急性胰腺炎的患者分为TPN治疗组和TPN EN联合治疗组,共有101例患者按要求完成试验,其中TPN治疗组56例,TPN EN联合治疗组45例.重症急性胰腺炎的诊断依据采用1992年亚特兰大国际会议分类标准.重症急性胰腺炎严重度评估依据:Ranson标准、APACHE:Ⅱ评分、Balthazar CT积分.结果 两组患者人院时年龄、性别及重症急性胰腺炎严重度评分诸方面均无显著性差异.与TPN治疗组相比,TPN EN联合治疗组患者的APACHElI评分及Binder合并症积分明显改善;并发症和平均住院时间明显缩短,住院费用明显降低,病死率降低(0% vs 7.5%).但血清淀粉酶和乳酸脱氢酶活性治疗前后无明显变化.结论 全胃肠外营养和肠内营养联合应用可显著改善重症急性胰腺炎患者的营养状况及预后,缩短住院时间.降低住院费用.  相似文献   

8.
中医药治疗淤胆型肝炎用药规律分析   总被引:1,自引:0,他引:1  
淤胆型肝炎又称毛细胆管炎型肝炎,其主要临床表现为黄疸,属于中医“黄疸”范畴。目前中医药疗法在淤胆型肝炎的治疗过程中得到了广泛的应用,为探求其用药规律,笔者查阅了1995年以来的相关文献,共得到有效方剂81首,涉及中药113味,共出现768次(下文中药物分类、性味、功效、归经等均依据凌一揆教授主编五版高等中医药院校教材《中药学》)。通过分析,发现治疗淤胆性肝炎的中药在使用上有以下规律。1 用药以活血祛瘀、清热、利水渗湿类药为主其功效分类分布及使用频率见表1。表1 中药功效分类分布及其使用频率功效分类味数味次使用频率(%)活血…  相似文献   

9.
中药大黄治疗重症急性胰腺炎69例体会   总被引:1,自引:1,他引:0  
重症急性胰腺炎(SAP)发病急剧,病死率高,病程后期合并深部真菌感染是患者致死的主要原因之一.近年来,笔者采用中药大黄治疗69例SAP患者,效果良好.现报告如下.  相似文献   

10.
重症急性胰腺炎(SAP)是临床上非常凶险的一种疾病,治疗的关键在于早期干预阻断病情进展.本研究应用早期经鼻空肠管中药灌注联合早期持续血液滤过治疗SAP,疗效满意,现报道如下.  相似文献   

11.
BACKGROUND: Chinese herbal medicines are commonly used to improve general health and well-being despite limited scientific data to support their efficacy. We conducted a randomized, double-blind, placebo-controlled trial to determine whether an herbal remedy that is used widely in China was associated with changes in quality of life, energy, memory, sexual function, and qi (the Chinese concept of "vital energy" that is important in general health). METHODS: Residents (n = 237) of Beijing, China, who were aged > or =60 years and had self-reported decreased energy, memory, or sexual function, were randomly assigned to take four tablets of a Chinese herbal formula or of an identical placebo, three times a day for 30 days. Patients returned for one follow-up visit after 30 days for assessment of all outcomes. The main outcome measures were changes in quality of life at 30 days as measured by the 12-Item Short Form Health Survey (SF-12) Mental and Physical Component Summary scales. RESULTS: Use of Chinese herbs was associated with a small benefit in the Mental Component scale (difference of 1.9 points; 95% confidence interval [CI]: 0.1 to 3.6) and no benefit in the Physical Component scale (difference of -0.1 points; 95% CI: -1.7 to 1.5) as compared with placebo. A small improvement in the qi scale was no longer significant after adjusting for baseline differences in this score between groups. There was no improvement in physical performance, memory, or sexual function. The herbal product was well tolerated. CONCLUSION: Short-term use of a mixture of Chinese herbs was associated with a small benefit in one measure of mental health that is of unclear clinical importance.  相似文献   

12.
The use of herbs has been advocated as an alternative treatment strategy for human immunodeficiency virus-related illness. To describe the use of medicinal herbs among acquired immunodeficiency syndrome clinic patients and to investigate possible toxic effects, we interviewed 114 randomly selected patients attending a university-based acquired immunodeficiency syndrome clinic and performed a structured review of the literature to identify potential adverse effects of herbal use. Twenty-five participants (22%) reported using one or more herbal products in the past 3 months. Of those taking herbs, six (24%) were unable to identify the herb that they had used. The mean number of herbal tablets taken was 4.5 tablets per day, and 12 patients (48%) reported taking herbs for longer than 90 days. The median cost to patients for their herbs was $18 per month. Of those taking herbs, five (20%) stated that their primary medical provider was unaware of their herb use, and four (16%) were involved in clinical drug trials while using herbs. Several patients reported taking herbs in doses at which potential adverse effects were identified in our literature review. These adverse effects include dermatitis, nausea, vomiting, diarrhea, thrombocytopenia, coagulopathies, altered mental status, hepatotoxicity, and electrolyte disturbances. Seven patients (28%) reported experiencing symptoms that could have been caused by one or more of the herbal products that they were taking. Physicians and clinical investigators need to inquire about patients' use of herbs. Patient care and clinical trials could be distorted because pharmacologic effects of herbs can resemble commonly occurring symptoms in human immunodeficiency virus disorders as well as side effects of prescribed or investigational medications.  相似文献   

13.
PURPOSE: The purpose of this article is to examine how Chinese herbal medicines are used in the treatment of diabetes, focusing on potential benefits and risks. METHODS: Medline, expert interviews, and Internet searches were used to identify Chinese herbal medicines with antidiabetic properties and their diabetes-related health claim, proposed antidiabetic effect, adverse effects, contraindications, and drug interactions. RESULTS: Twenty-three herbs and 5 herbal formulas were selected for review. Antidiabetic health claims included increasing serum insulin, decreasing blood glucose, increasing glucose metabolism, and/or stimulating pancreatic function. Side effects were few or not reported. CONCLUSIONS: The use of Chinese herbal medicines in diabetes is promising but still far from proven. Diabetes educators need to be aware of the risks and benefits of herbal medicines. Patients should be asked about the use and source of herbal medicines and carefully monitored for drug interactions and adverse effects.  相似文献   

14.
Prevalence of dislipidemia is increasing rapidly in China and there has been a growing interest in Chinese herbal medicine for the treatment of hyperlipidemia both inside and outside China. In this article, lipids regulating effects of 9 herbs or their extracts and 5 herbal formulae which have been published in English-language literature are reviewed. Although evidence from animals and humans consistently supports the therapeutic activities of these Chinese herbal medicines, few multi-center large-scale clinical trials have been conducted to confirm the efficacy and evaluate their safety.  相似文献   

15.
16.
OBJECTIVE: To determine how frequently herbal remedies are employed as alternative therapies in rheumatic diseases, and the historical justification for their use. METHODS: We conducted a survey in 250 outpatients in the rheumatology clinic of a teaching hospital in México. We registered general demographic information and the previous use of herbal remedies for rheumatic conditions, how effective they were, and the presence of adverse effects during their use. We identified the herbs employed, and cross-checked them with medical texts from the 16th through the 18th centuries on the use of herbal remedies. RESULTS: Of 250 surveyed patients, 126 (51%) had used herbal remedies for their rheumatic conditions. 63% of all users reported them to be effective for the purpose they had been prescribed. 12% reported adverse effects, none of them life-threatening. Being a user had no relation with the patients' formal education. Three patients did not answer the survey. We were able to identify 67 plants. One third of these are either prescribed for rheumatic conditions in the consulted bibliography, or else were used for the same purpose by ancient Mexican cultures. CONCLUSION: Herbal remedies are frequently used for rheumatic conditions. Some of them have an historical antecedent for their use in rheumatic conditions. They deserve a cautious evaluation as adjunctive therapies in rheumatic diseases.  相似文献   

17.
目的分析徐浩教授治疗冠心病的处方用药规律和经验。方法从门诊病历中选取并整理徐浩教授治疗冠心病处方543首,提取中药处方数据,建立标准化医案数据库,利用古今医案云平台系统的用药统计分析、聚类分析、复杂网络分析等数据挖掘功能,分析医案中处方的用药频次、性味归经、常用药对及核心处方等数据。结果整理处方543首,涉及药物217种,治疗冠心病的高频中药有黄芪、丹参、柴胡、炙甘草、三七粉、瓜蒌等,药性多属温、微寒、平,药味多属甘、苦味,主要归经为肝、肺、心经,功效以活血祛瘀、利水消肿、生津养血为主。常用药对有黄芪-丹参、丹参-黄芪、黄芪-三七粉等。聚类分析可将药物分为4类,分别为活血祛瘀止痛,调畅气机,宣痹通阳,益气养血、健脾化痰。复杂网络分析得出核心药物为黄芪、丹参、三七粉、瓜蒌、柴胡、黄芩、炙甘草、天麻、枳壳、制何首乌、党参、延胡索、川芎、薤白。结论徐浩教授治疗冠心病药物多为温、平、甘、苦,归肝、肺、心经,治疗多气血同治、寒热同调、虚实兼顾、注重调神,以温阳补气、活血化瘀、理气化痰、安神定志为法。  相似文献   

18.
目的:整理并总结金元四大家治疗便秘病用药规律,以期为临床中医治疗该病提供文献学证据,并为完善金元四大家学术体系提供统计学依据作出贡献。方法:收集金元四大家医学著作中与便秘病相关的中药处方,对符合纳入标准的中药处方进行统计,利用WPS Excel软件建立方药数据库,应用SPSS 20.0统计软件对中药的频数分析、因子分析、相关性分析,运用IBM SPSS Modeler 18.0统计软件对治疗便秘病的高频药物进行数据挖掘,采用Cytoscpae软件绘制高频药物核心网络图。结果:共获得治疗便秘病的中药处方67首,其中涉及中药111味,总计出现频次571次。统计出金元四大家治疗便秘病常用高频药物以补气药、清热药、泻下药、解表药、理气药及补血药为主,根据高频药物关联分析,挖掘出38对常用药对和15组常用药组。根据高频药物相关性分析,绘制药物核心网络图,挖掘出4组临床常用核心组方。结论:研究发现金元四大家认为便秘病与脾、大肠、胃三脏关系密切,治疗上以"温阳益气,升降结合""苦寒攻下""滋阴润燥,辛润活血"及"祛风除湿"为基本大法,可治疗气虚便秘、气滞便秘、热结便秘、、瘀血便秘、血虚便秘及湿秘等,常用方剂有润肠汤、黄芪人参汤、木香槟榔丸、生津甘露汤、脾约丸等,并总结4组核心组方,以上研究结果对中医临床治疗该病具有指导意义,并为更好理解金元四大家学术思想提供数据支持。  相似文献   

19.
目的基于R软件多种数据挖掘技术分析韩振蕴教授治疗抑郁症的临床用药规律。方法基于R软件对韩振蕴教授治疗抑郁症的临床用药进行基本分析、Pearson相关系数的相关分析、Apriori算法相关度分析、层次聚类、K均值(K-means)聚类、围绕中心点的划分(PAM)聚类分析等。结果相关分析表明,韩振蕴教授临床用药时,高频用药的药物组合中,以疏肝健脾理气类药物的药物组合为主;中高频的药物组合中,以疏肝健脾理气类和补肾填精类药物为主。聚类分析表明,韩振蕴教授临床用药主要可以分为疏肝行气健脾、活血通络、补肾滋阴3类药物。结论韩振蕴教授治疗抑郁症时临床用药主要以疏肝行气健脾、活血通络、补肾滋阴的药物为主,辨证施治予以治疗。  相似文献   

20.
The increasing use of herbal products by patients with cardiovascular disease represents a clinical challenge to physicians. The use of herbal products is increasing in our society, and less than 50% of patients using herbal products report this information to their physicians. In addition, physicians often lack the knowledge base for herbal medications to effectively counsel patients regarding adverse effects and potential herb-drug interactions. This article reviews Western and traditional Chinese herbs that are commonly used by patients with cardiovascular diseases, herbs noted to have adverse cardiovascular effects, and herbs that may potentially interact with commonly prescribed cardiovascular medications.  相似文献   

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