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1.
本文式图通过对原虫感染和临床发病的年龄别影响的建模,评价保守和株特异的免疫应答的相对作用。建模实施清楚地表明,实际观察到的年龄别病率对以下假设是最好的解释,即抗保守决定簇的免疫应答必须积累到某个阀值才具有“抗感染”保护性,而“抗发病”免疫则随着暴露而呈线性发展。  相似文献   

2.
四川阿坝牧区包虫病血清流行病学调查报告   总被引:2,自引:1,他引:1  
四川阿坝牧区包虫病血清流行病学调查报告陈开华,杨伯全,邱加闽,陈兴旺,杨仁才,魏跃辉,王建光(四川省阿坝州卫生防疫站,马尔康624000;四川省寄生虫病防治研究所;红原县卫生防疫站;若尔盖县卫生防疫站;阿坝县卫生防疫站)为了解四川省阿坝州西北部牧区地...  相似文献   

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4.
肺结核病例因症就诊的发现   总被引:4,自引:0,他引:4  
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5.
国外老年流行病学研究概况   总被引:6,自引:0,他引:6  
国外老年流行病学研究概况湖北省梨园医院(430077)刘汴生刘汴生主任医师近几年来,老年流行病学的研究主要集中于探索影响人体衰老的因素,探讨老年常见病的分布状况和发病规律,从而寻求延缓衰老、预防疾病、提高全社会老年人生命质量的对策。本文就以下几个方面...  相似文献   

6.
老年流行病学调查在国内的开展情况   总被引:4,自引:0,他引:4  
老年流行病学调查在国内的开展情况卫生部北京老年医学研究所(100730)何慧德何慧德教授1中国老年流行病学调查工作我国开始于1958年,当时开展最早的是中国科学院动物研究所老年学研究室。他们曾组织傅湘琦等对徐水县60岁以上的老人作了调查。1959年又...  相似文献   

7.
青海省玉树州两起人间鼠疫血清流行病学调查张发斌于守鸿(青海省地方病防治研究所,西宁市811602)1996年8月6日~8月26日,青海省玉树州囊谦县拉索尼二队及玉树县下拉秀钻多四社连续发生两起人间鼠疫,发病3人,均系淋巴腺鼠疫,治疗后痊愈,无继发病例...  相似文献   

8.
糖尿病足病的流行病学和分级   总被引:6,自引:0,他引:6  
简单的分级系统(Edmonds和Foster)能够清楚地区别糖尿病足的神经病变和神经缺血性病变。Wagner分类系统过于简单,不是基于糖尿病足的自然病程,很难区别坏疽是由于缺血还是感染造成。美国德克萨斯州大学的分级方法比较复杂、耗时,在繁忙的门诊不适用,更适合研究时应用。简单分级系统根据足病的自然过程,简单实用,利于临床糖尿病足病的治疗与护理。  相似文献   

9.
新疆芳草湖农场人群包虫病血清流行病学调查   总被引:1,自引:1,他引:0  
新疆芳草湖农场人群包虫病血清流行病学调查吕大元1杨永海2孟娜嘉1(1.新疆芳草湖农场卫生防疫站,831208;2.呼图壁县地方病办公室)新疆是包虫病高发病区之一。芳草湖农场位于昌吉州呼图壁县境内,地处天山北麓,准噶尔盆地南缘的冲积平原上。总面积949...  相似文献   

10.
哈尔滨市城乡人群囊虫病血清流行病学调查   总被引:2,自引:0,他引:2  
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11.
During 1985-1995, illnesses clinically and epidemiologically compatible with Brazilian spotted fever were identified in 17 patients in the county of Pedreira, in the state of S?o Paulo, Brazil. Spotted-fever group rickettsial infection was confirmed by serology and/or immunostaining of tissues in 10 of these patients. Immunostaining confirmed infection in a 37-year-old pregnant patient, although rickettsial antigens were not demonstrable in the tissues of the fetus. A serosurvey was conducted in four localities in the county to determine the prevalence of subclinical or asymptomatic infections with spotted fever group rickettsiae. Five hundred and twenty-five blood samples were tested by an indirect immunofluorescence assay for antibodies reactive with Rickettsia rickettsii. Twenty-two (4.2%) of these samples demonstrated titers > or = 1:64. The results indicate that Brazilian spotted fever is endemic within this region of Brazil.  相似文献   

12.
不同血清学方法对调查现场包虫病人血清的检测及评价   总被引:3,自引:0,他引:3  
本文应用青海囊型包虫抗原Dot-ELISA、IHA和新疆囊型包虫抗原ELISA、泡型包虫EM18抗原ELIB对流行病学调查现场的206例包虫病人血清进行了检测。结果表明青海囊型包虫抗原Dot-ELISA和IHA对囊型包虫病人血清的阳性率分别是90.37%和91.98%;新疆囊型包虫抗原ELISA对囊型包虫病人血清的阳性率为75.94%;三种方法对钙化灶型囊型包虫病人血清的阳性率分别是77.27%、  相似文献   

13.
目的 探讨三江源地区人群鼠疫血清流行病学特点,为制订青海省鼠疫预防控制策略提供科学依据.方法 在青海省三江源地区,对4个县(市)进行鼠疫血清流行病学调查.并应用间接血凝试验(IHA)对调查人群进行鼠疫血清F1抗体的检测.结果 4个县(市)共检测2508人,鼠疫血清学阳性率为2.31%(58/2508),地区间阳性率比较差异有统计学意义(X2=19.30,P<0.01);男、女阳性率分别为2.54%(32/1261)、2.09%(26/1247),阳性率比较差异无统计学意义(X2=0.65,P0.05);牧民和干部血清学阳性率分别为3.54%(44/1243)和6.47%(11/170);藏族和汉族血清学阳性率分别为2.40%(56/2335)和1.47%(2/136);随着年龄增长,阳性率呈上升趋势,人体鼠疫血清抗体滴度最高为1:640.结论 三江源地区人群中存在不同程度鼠疫隐性感染者,血清学阳性率与当地动物鼠疫流行密切相关.  相似文献   

14.
Murine typhus (MT) is a cause of fever of intermediate duration in the south of Spain. Rickettsia typhi has been described as the MT etiological agent. Rickettsia felis produces an infection similar to MT. The aim of the study is to determine their seroprevalence in humans in Catalonia. Antibodies to Rickettsia typhi and Rickettsia felis from 217 serum samples were examined by indirect immunofluorescence assay (IFA). Age, gender, residence area, contact with animals, and occupation were surveyed. Rickettsia typhi and Rickettsia felis seroprevalences were 8.8% and 3.2%, respectively. Rickettsia typhi was present in 7.6% of the samples in urban, 8.5% in semirural, and in 21.4% in rural areas, whereas Rickettsia felis was present in 3.5% in urban, 1.7% in semirural, and 7.1% in rural area. The only statistically significant association observed was that between Rickettsia felis seropositivity and age. Our data seem to indicate the presence of Rickettsia typhi and Rickettsia felis in humans in Catalonia.  相似文献   

15.
目的 全面、准确了解和评价2006年山西省居民食用盐现状,及时发现问题并采取相应的干预措施.方法 每县按东、南、西、北、中5个方位选取9个乡镇,每个乡镇选取4个村,每个村采取8户居民户盐样,送各县疾病预防控制中心(CDC)实验室检测盐碘含量.结果 全省119个县(市、区)除高碘乡镇外监测居民食用盐33 773份,非碘盐率2.95%,碘盐合格率97.34%,合格碘盐食用率94.51%,盐碘均数30.9±8.0 mg/kg,盐碘中位数31.2 mg/kg.结论 与2005年相比,非碘盐率上升,合格碘盐食用率下降,距2010年95%的县实现消除碘缺乏病目标尚有差距.  相似文献   

16.
宁波市并殖吸虫病流行现状   总被引:1,自引:0,他引:1       下载免费PDF全文
收集2000-2007年宁波市疾控中心寄生虫病门诊并殖吸虫病病例资料,调查并殖吸虫病历史流行区人群自然感染情况,以及并殖吸虫第一、第二中间宿主和保虫宿主的感染情况。从2 643份疑似患者血清中检出并殖吸虫抗体阳性417份,阳性率为15.8%,男女比例为1︰1.19,多数病例存在外周血嗜酸粒细胞增高。历史流行区人群血清阳性率为3.1%(46/1 462),男性和女性的感染率分别为2.8%(18/649)和3.2%(26/813),两者差异无统计学意义(x2=0.183 3,P>0.05)。第一中间宿主川卷螺阳性率为0.05%(9/19 368),第二中间宿主长江华溪蟹和浙江华溪蟹阳性率为31.1%(15 627/50 313),保虫宿主阳性率为11.9%(52/438)。宁波市部分地区仍存在并殖吸虫病的自然疫源地。  相似文献   

17.
Rickettsial infection of cattle and sika deer from a pastureland in Hidaka District, Hokkaido, Japan was examined by serological and molecular methods. Serum samples from 8 of 83 (9.6%) cattle reacted with Rickettsia helvetica antigens in an IFA test, with titers ranging from 1:160 to 1:640, while serum samples from 15 of 22 (68.2%) deer were positive for R. helvetica, with titers ranging from 1:80 to 1:640. In a genus-specific nested PCR based on gltA, no cattle were positive for Rickettsia, while 14 of 22 (63.3%) samples obtained from deer tested positive. Sequence analysis revealed that positive samples from sika deer showed 100% nucleotide sequence identity with the known sequence of Rickettsia asiatica.  相似文献   

18.
1450 random serum samples of domestic ruminants from Egypt, Somalia and Jordan were investigated for complement fixing antibodies against Rickettsia and Chlamydia. Between 1.5 and 3.4% of the samples from the animals investigated had antibodies against the RMSF-group of Rickettsia, with exception of the sera from Somalian cattle and sheep from Jordan. Antibodies against Rickettsia of the Typhus-group were found in 4 cattle and 1 goat from Jordan and 2 sheep from Egypt; by agglutination test with type-specific antigen they were identified as antibodies against R. typhi. Using 2 different antigens, antibodies against Coxiella burnetii were found in every population tested. The prevalence was 2.0 to 12.2%, with the exception of cattle in Somalia, where only 1 positive serum (0.2%) was found. 27% of the serum samples from Jordan and 22% from Egypt but none of the 802 samples from Somalia had antibodies against Chlamydia. The results are discussed under an epidemiological point of view.  相似文献   

19.
Cases of Rocky Mountain spotted fever (RMSF) in North Carolina have escalated markedly since 2000. In 2005, we identified a county in the Piedmont region with high case numbers of RMSF. We collected ticks and examined them for bacterial pathogens using molecular methods to determine if a novel tick vector or spotted fever group rickettsiae (SFGR) might be emerging. Amblyomma americanum, the lone star tick, comprised 99.6% of 6,502 specimens collected in suburban landscapes. In contrast, Dermacentor variabilis, the American dog tick, a principal vector of Rickettsia rickettsii, comprised < 1% of the ticks collected. Eleven of 25 lone star tick pools tested were infected with "Rickettsia amblyommii," an informally named SFGR. Sera from patients from the same county who were presumptively diagnosed by local physicians with a tick-borne illness were tested by an indirect immunofluorescence antibody (IFA) assay to confirm clinical diagnoses. Three of six patients classified as probable RMSF cases demonstrated a fourfold or greater rise in IgG class antibody titers between paired acute and convalescent sera to "R. amblyommii" antigens, but not to R. rickettsii antigens. White-tailed deer, Odocoileus virginianus, are preferred hosts of lone star ticks. Blood samples collected from hunter-killed deer from the same county were tested by IFA test for antibodies to Ehrlichia chaffeensis and "R. amblyommii." Twenty-eight (87%) of 32 deer were positive for antibodies to E. chaffeensis, but only 1 (3%) of the deer exhibited antibodies to "R. amblyommii," suggesting that deer are not the source of "R. amblyommii" infection for lone star ticks. We propose that some cases of rickettsiosis reported as RMSF may have been caused by "R. amblyommii" transmitted through the bite of A. americanum.  相似文献   

20.
青海省玉树藏族自治州棘球蚴病流行现况   总被引:1,自引:0,他引:1       下载免费PDF全文
2006年分别选择青海省玉树、治多和称多等3县(州)的2个镇6个乡共27个自然村,对1岁以上常住居民用间接红细胞凝集试验(IHA)和B超进行棘球蚴病诊断检查。IHA共检2 251人,抗棘球蚴抗体IgG阳性率为9.2%(207/2 251);B超共检2 581人,患病率为4.1%(106/2 581)。女性IHA阳性率和患病水平(分别为11.3%和5.0%)均高于男性(分别为6.6%和3.0%)。IHA血清阳性者中,40岁组最高,占16.4%;患病率则随年龄增长而升高,60岁以上组最高,占15.5%。不同职业人群中IHA血清阳性率和患病率均以半农半牧为最高,分别占21.5%和11.4%。玉树州人群棘球蚴病抗体阳性率和患病率均处于较高水平。  相似文献   

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