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Purpose

To evaluate meibomian gland morphology and function in children without ocular discomfort.

Method

A total of 266 eyes of 266 children without signs or symptoms of ocular surface dysfunction were enrolled. Morphology of meibomian glands (MG) and non-invasive break-up time (BUT) was assessed by noncontact meibography. Based on lipid layer thickness (LLT) of the tear film measurements, 66 children were chosen to be assessed by meibomian glands yielding liquid secretion (MGYLS).

Results

Based on the presence of physiologic conjunctival follicles (PCF), participants were divided into normal or PCF groups. The distortion and deficiency of MG function was significantly higher in PCF group (P?=?0.002, 0.007, respectively). Five different gland duct shapes (vertical, tortuous, overriding, hooked, U-shaped) were observed. MG deficiency was positively correlated with age (R?=?0.362, P?<?0.001). Distortion and the number of MG showed no correlation with age (P?>?0.05). However, distortion and deficiency of MG were negatively correlated with LLT (P?<?0.001, P?<?0.01).

Conclusion

Children with PCF had significantly more MG distortion and deficiency which was associated with LLT. These results prompt future studies to determine if changes in MG morphology are congenital or acquired.  相似文献   

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目的分析浙南地区外伤性真菌性角膜炎患者的人口学及临床特征。方法收集2016年1月至2020年12月温州医科大学附属眼视光医院外伤后真菌性角膜炎562例(562眼)的临床资料,回顾性分析其人口学特征、致病因素、致病菌属、用药史、临床体征及治疗方式;结果农民为主要患病人群,共332例(59.1%)。41?80岁年龄段为主,共484例(86.2%)。男女比例为2.7:1。主要分布地区为温州市鹿城K共65例(11.6%),植物外伤为主要致病因素,共225例(40.0%)。主要致病菌属为镰刀菌属163例(41.6%)413例(73.5%)可见明显溃疡灶:130例(23.1%)接受手术治疗。联合角膜共焦显微镜、刮片镜检、培养鉴定,阳性检出率为95.7%(201/210)。结论中老年男性农民为主要患病人群,镰刀菌属是主要的致病菌属,植物伤是主要致病菌素。联合角膜共聚焦显微镜.刮片镜检,培养鉴定这者检查能提高外伤性真菌性角膜炎阳性检出率。  相似文献   

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Objectives

To investigate the outcomes for correction of involutional lower eyelid entropion by wedge resection of the tarsus combined with the modified Hotz procedure.

Design

Retrospective study.

Participants

Patients with lower eyelid involutional entropion that was surgically repaired by wedge resection of the tarsal plate combined with the modified Hotz procedure.

Methods

In a consecutive series of 43 patients with involutional lower eyelid entropion, wedge resection combined with the modified Hotz procedure was performed with an average follow-up period of 29.6 months (range, 6–62 months).

Results

Among the patients, 93% had an excellent outcome within the follow-up period. For one patient, the outcome of both eyes was poor. For another patient, incision dehiscence of the eyelid margin in one eye occurred after the stitches were removed. The incision was sutured again, and it healed well. One patient complained of foreign body sensation in one eye after removal of the skin stitches. The complaint was resolved after wearing a corneal contact lens. No other significant complications occurred.

Conclusions

In our clinic, tarsal plate wedge resection combined with the modified Hotz procedure has been highly effective for correction of involutional lower eyelid entropion. Although this approach does not directly address lateral canthal tendon laxity, it does preserve the eyelid in case there is a future need for reconstruction due to ocular surface disease or trauma. Thus, wedge resection of the tarsal plate combined with modified Hotz procedure is a safe and effective method for involutional lower eyelid entropion.  相似文献   

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With the technological revolution in medicine that occurred between the two World Wars came awareness of a need for an ophthalmic institution that would combine clinical and basic scientific research, professional training, and patient services. The history of the Institute of Ophthalmology of the University of London is reviewed by Sir Stewart Duke-Elder, who was instrumental in the foundation and development of the Institute and who currently serves as its President.  相似文献   

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U型插管法在泪道重建中的应用   总被引:1,自引:0,他引:1  
张瑞君  张薇  傅永艳  张柏新 《眼科》2003,12(5):300-301
目的:探讨U型插管法在泪道重建中的应用价值。方法:用硬膜外麻醉导管U型泪道插管的方法,对下泪小管断裂、泪小点狭窄、鼻泪管阻塞患者进行治疗。结果:21例下泪小管断裂者全部成功(其中2例泪囊切开,逆行找泪小管鼻侧断端),3例泪小点狭窄者2例成功,14例鼻泪管阻塞者11例成功。结论:U型插管法在泪道重建中方法简便、固定良好、不影响美观、留置时间长、效果确切。  相似文献   

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