启东1972～2001年恶性肿瘤发病率时间趋势分析

目的运用时间趋势分析方法研究启东恶性肿瘤的变化趋势。方法利用启东肿瘤登记处积累的1972~2001年的登记资料,分析启东地区常见肿瘤发病率的变化趋势。计算粗率、调整率和变化百分比;配合调整率的线性回归模型,估计发病率的APC;同时分析各部位肿瘤发病率的年度变化贡献率及其统计学检验方法。结果男性中鼻咽癌、食管癌、胃癌、皮肤癌等部位发病率呈下降趋势,结肠癌、直肠癌、胰腺癌、肺癌、前列腺癌、膀胱癌、肾癌、脑肿瘤、非何杰金氏病以及白血病的发病率呈明显上升趋势;女性中鼻咽癌、胃癌、肠癌、皮肤癌、宫颈癌、肾癌等发病率呈下降趋势,结肠癌、直肠癌、胰腺癌、肺癌、卵巢癌、膀胱癌、脑肿瘤和白血病的发病率呈上升趋势。男性肿瘤中呈下降趋势贡献最大为胃癌,其次为肝癌;而发病率呈上升趋势的肿瘤中贡献最大的为肺癌,其次为直肠癌。在女性肿瘤呈下降趋势中贡献最大的是宫颈癌和胃癌;而发病率呈上升趋势的肿瘤贡献最大的是肺癌,其次为乳腺癌。结论时间趋势分析方法在研究恶性肿瘤发病率或死亡率变化趋势时值得推广。     

恶性肿瘤发病率的时间趋势分析方法

目的 介绍恶性肿瘤发病率或死亡率的时间趋势分析方法。方法 利用上海市肿瘤登记处积累的1991～1999年的登记资料为例,分析了上海市区常见肿瘤发病率的变化趋势。首先是计算粗率、标化率和变化百分比(PC);并通过配合标化率的线性回归模型,估计发病率的年度变化百分比(APC);同时分析各部位肿瘤发病率变化在全部上升或下降的肿瘤趋势改变中的贡献,即年度变化贡献率,及其统计学检验方法。结果 9年间上海市区男性主要恶性肿瘤中食管癌和胃癌发病率呈现下降趋势,而结肠癌、直肠癌、胆囊癌、胰腺癌、前列腺癌、膀胱癌、肾癌、白血病发病率上升;女性肿瘤中也是食管癌和胃癌发病率下降,而结肠癌、直肠癌、肺癌、乳腺癌、胆囊癌、子宫内膜癌、卵巢癌、膀胱癌、肾癌发病率上升;男女性这些变化都达到了统计学意义(P<0.05或P<0.01)。其他部位有较小的趋势变化,没有统计学意义。男性癌症中,以胃癌和食管癌下降显著,APC和贡献率分别为-2.99％(加权估计值,下同)和-65.72％、-2.90％和-17.07％;上升显著的是前列腺癌(2.30％和21.46％)、结肠癌(2.94％和18.62％)和直肠癌(3.11％和15.09％)。女性肿瘤中,同样以胃癌和食管癌下降显著,APC和贡献率分别为-6.05％和-39.55％、-1.08％和-35.19％;上升显著的是乳腺癌(2.81％和28     

上海市嘉定区1996—2006年恶性肿瘤发病情况分析

[目的]分析上海市嘉定区居民恶性肿瘤发病的特征,为该区恶性肿瘤流行趋势评价和肿瘤综合防治提供科学依据。[方法]对嘉定区1996—2006年恶性肿瘤发病资料进行统计分析。1996—2001年按国际疾病分类法ICD-9进行分类,2002—2006年按国际疾病分类法ICD-10进行分类,计算粗发病率和标化发病率。[结果]1996—2006年嘉定区居民恶性肿瘤粗发病为285.23/10万,标化发病率为176.25/10万。男性粗发病率为332.20/10万,女性粗发病率为238.99/10万,男性发病率高于女性,性别比为1.37∶1。无论男女,45岁后随年龄的增长发病率大幅上升,上升幅度男性大于女性。居民恶性肿瘤发病居前10位的分别是肺癌、胃癌、结直肠癌、肝癌、乳腺癌、食管癌、胰腺癌、脑癌、膀胱癌和胆囊癌。肺癌、结直肠癌、乳腺癌、胰腺癌、前列腺癌和宫颈癌等癌症的粗发病率逐年上升,其他恶性肿瘤发病则比较稳定。[结论]嘉定区1996—2006年居民恶性肿瘤的发病率呈上升趋势,肺癌、胃癌、结直肠癌、肝癌和乳腺癌等是威胁人群的主要恶性肿瘤,普及防癌健康教育,有针对性地做好高危人群的早诊早治工作是我区今后肿瘤防控工作的关键。     

2001—2010年武威市凉州区恶性肿瘤发病特征及其流行趋势分析

目的探讨武威市凉州区恶性肿瘤发病特征及其流行趋势,为肿瘤防治规划的制定和防治效果的评价提供依据。方法资料来自肿瘤登记报告,粗发病率、人口调整率、截缩率和累积率等,统计指标按照《中国肿瘤登记工作指导手册》介绍的方法进行,两个率的比较采用χ2检验。结果 2001—2010年恶性肿瘤粗发病率为231.5/10万,中国人口调整率为208.6/10万,性比值(男/女)为1.9,男女性粗发病率经统计学检验,χ2=2126.38,P<0.01。男性前9位恶性肿瘤发病顺位依次为胃癌、食管癌、肺癌、肝癌、大肠癌、白血病、脑肿瘤、恶性淋巴瘤和胰腺癌,前9位恶性肿瘤占男性全部恶性肿瘤发病的90.1%;女性前11位恶性肿瘤发病顺位依次为胃癌、食管癌、乳腺癌、肺癌、大肠癌、宫颈癌、肝癌、恶性淋巴瘤、脑肿瘤、白血病和胰腺癌,前11位恶性肿瘤占女性全部恶性肿瘤发病的81.8%。年龄别发病率有随着年龄增长而升高的趋势。结论武威市凉州区恶性肿瘤发病呈上升趋势,胃癌、食管癌、肺癌和女性乳腺癌是武威市凉州区肿瘤防治的重点。     

上海市卢湾区2002—2007年恶性肿瘤发病及死亡状况分析

目的分析上海市卢湾区2002—2007年居民新发恶性肿瘤发病情况与死亡分布特征。方法对2002—2007年卢湾区居民新发肿瘤及死亡资料进行统计学分析。结果 2002—2007年居民发病率总体呈上升趋势,死亡率则有下降趋势,男性的发病率及死亡率均高于女性,年龄别发病率和死亡率呈上升趋势。男性恶性肿瘤发病居于前5位的分别为肺癌、大肠癌、胃癌、肝癌和前列腺癌,死亡率位于前5位的为肺癌、胃癌、大肠癌、肝癌、食管癌和胰腺癌;女性恶性肿瘤发病居于前5位的分别为乳腺癌、大肠癌、肺癌、胃癌和肝癌,死亡率位于前6位的为肺癌、大肠癌、乳腺癌、胃癌、肝癌和胰腺癌。肺癌居男性发病和死亡的首位,前列腺癌发病已上升到第5位,乳腺癌则高居女性肿瘤发病首位。胰腺癌的死亡率明显提高,已分别位居男女死亡的第6位。结论卢湾区恶性肿瘤重点监测人群为40~50岁组,重点防治的癌种为肺癌、乳腺癌、前列腺癌和胰腺癌等。     

兰州市城关区2008-2012年恶性肿瘤发病构成与流行趋势分析

目的 了解兰州市城关区居民恶性肿瘤的发病情况及其变化趋势,为制定肿瘤防治规划和开展重点人群综合防治工作提供科学依据.方法 依据甘肃省肿瘤登记处在具有诊断能力的医疗机构收集的恶性肿瘤报告卡,整理兰州市城关区2008年1月1日-2012年12月31日常住人口中恶性肿瘤的发病资料,统计分析恶性肿瘤发病例数、发病率、构成比、标化率及累积率等指标.结果 2008-2012年兰州市城关区恶性肿瘤发病率分别为193.30/10万、222.47/10万、208.89/10万、221.17/10万和249.24/10万;男性发病率波动于216.60/10万～283.36/10万之间,女性发病率波动于169.70/10万～215.63/10万之间,男女性发病率总体呈上升趋势.男性恶性肿瘤发病率和构成比明显高于女性;恶性肿瘤发病率呈随着年龄增长而逐渐上升的趋势;男女性别发病比为1.3∶1.恶性肿瘤发病居前10位的依次是肺癌、胃癌、结直肠癌、肝癌、乳腺癌、宫颈癌、食管癌、脑肿瘤、胆囊癌和膀胱癌.2009年膀胱癌位居肿瘤发病顺位的第7位,乳腺癌2012年位居肿瘤发病顺位的第4位.结论 兰州市城关区恶性肿瘤发病率呈逐年上升趋势,肺癌、胃癌、结直肠癌、肝癌和女性乳腺癌是兰州市城关区恶性肿瘤防治的重点.应早期开展健康促进干预,采取有针对性的防癌措施,降低恶性肿瘤的发病率,提高居民的健康水平和生活质量.     

2010-2012年湖州市恶性肿瘤发病状况分析

目的了解湖州市2010—2012年恶性肿瘤发病情况,为肿瘤防治提供依据。方法利用浙江省慢性病监测系统收集数据,采用2010年1月111至2012年12月3113年浙江省湖州市户籍人口肿瘤病例进行统计分析。结果湖州市2010—2012年累计报告恶性肿瘤23999例,其中男性13938例（58．08％）,女性10061例（41．92％）;恶性肿瘤年平均粗发病率299．90／10万（男性为345,28／10万,女性为253.71／10万）,中国人口标化发病率为245．07／10万（男性为278．18／10万,女性为212．90／10万）;男性发病前10位恶性肿瘤为肺癌、胃癌、肠癌、肝癌、食管癌、前列腺癌、膀胱癌、胰腺癌、肾癌、鼻咽癌,女性发病前10位恶性肿瘤是乳腺癌、肺癌、肠癌、胃癌、甲状腺癌、宫颈癌、肝癌、胰腺癌、卵巢癌、胆囊癌;恶性肿瘤发病率随年龄增长呈现上升趋势,且3年间,湖州市恶性肿瘤发病率呈逐年递增趋势（P〈0．05）。结论恶性肿瘤对湖州市居民的健康危害严重,改善环境,提倡健康生活理念,改变不良行为习惯,做好肿瘤防治工作是当务之急。     

舟山市2000～2009年恶性肿瘤发病情况分析

目的了解舟山市近10年恶性肿瘤发病情况及人群分布,为制定预防控制措施提供科学依据。方法对2000年1月至2009年12月间确诊为恶性肿瘤的病例进行调查分析。结果 2000～2009年舟山市恶性肿瘤总发病率为167.76/10万,其中男性发病率207.21/10万,女性发病率127.96/10万;发病率顺位依次为:肺癌、胃癌、肝癌、乳腺癌、甲状腺癌、直肠癌、食管癌、结肠癌、膀胱癌、胰腺癌、子宫颈癌、鼻咽癌。结论舟山市的恶性肿瘤发病率呈逐年上升趋势,要加强恶性肿瘤的早期监测,及早发现患者、及早治疗。     

2013—2015年无锡市城区恶性肿瘤发病与死亡分析

了解无锡市城区恶性肿瘤发病和死亡状况,为开展肿瘤防治工作提供依据。方法收集整理2013—2015年无锡市区新发恶性肿瘤病例报告和死亡资料,计算恶性肿瘤发病(死亡)率、标化发病(死亡)率、年龄别发病(死亡)率和0~74岁累积率等指标,分析前10位恶性肿瘤发病与死亡的变化情况。结果 2013—2015年,无锡市区恶性肿瘤发病率为347.06/10万,标化发病率为231.26/10万,死亡率为227.97/10万,标化死亡率为143.06/10万,0~74岁累积发病率为20.81%,累积死亡率为11.93%。40岁前全人群恶性肿瘤发病率、死亡率均处于较低水平,发病率在55岁、死亡率在70岁以后迅速攀升,80~84岁组均达到高峰(发病率:1 534.45/10万、死亡率:1 601.33/10万)后有所下降。20~54岁男性恶性肿瘤发病率低于女性,55岁后男性发病率、45岁后男性死亡率均上升迅速并明显超过女性。发病率居前10位的为胃癌、肺癌、结直肠癌、肝癌、乳腺癌、食管癌、胰腺癌、前列腺癌、子宫颈癌、膀胱癌,占所有恶性肿瘤发病的77.37%;死亡率居前10位的依次为肺癌、胃癌、肝癌、结直肠癌、食管癌、胰腺癌、淋巴瘤、乳腺癌、胆囊癌、白血病,占全部恶性肿瘤死亡的85.07%。结论无锡市区恶性肿瘤发病率和死亡率均较高,应根据主要流行癌种发病和死亡态势,进一步有针对性的加强防控工作。     

2005-2007年兰州市恶性肿瘤发病状况分析

目的 探讨兰州市人群恶性肿瘤发病状况及趋势,分析癌谱结构,确定重点防治人群.方法 收集兰州市5区2005年1月1日～2007年12月31日常住人口中所有新发和死亡的恶性肿瘤病例和中枢神经系统良性肿瘤,统计分析发病率及其相关指标.结果 2005 -2007年兰州市5区登记报告恶性肿瘤10 594例,恶性肿瘤发病率为204.39/10万,其中,男性为229.29/10万,女性为177.52/10万;中国人口标化发病率为164.98/10万,男性为191.51/10万,女性为138.51/10万;男性恶性肿瘤发病率高出女性29.16％.发病率居前10位的肿瘤,男性依次是肺癌、胃癌、肝癌、结直肠癌、食管癌、膀胱癌、胰腺癌、肾癌、前列腺癌和淋巴瘤,占全部恶性肿瘤的82.12％;女性依次是乳腺癌、肺癌、宫颈癌、胃癌、结直肠癌、胆囊癌、肝癌、卵巢癌、子宫体癌和脑及神经系统肿瘤,占全部恶性肿瘤的75.57％.5区中,城关区恶性肿瘤病例数最多,占兰州市的50.39％;西固区恶性肿瘤发病率最高,为225.03/10万.3年间,兰州市恶性肿瘤发病率呈上升趋势(x2趋势=2.84,P=0.005).男性发病率上升趋势显著(x2趋势=2.37,P=0.018).结论 兰州市居民恶性肿瘤以肺癌、胃癌、结直肠癌和肝癌及女性乳腺癌和宫颈癌为主,严重威胁居民健康.西固区是重点防治地区,男性和老年人群是重点防治对象.     

Incidence and mortality due to cancer in Navarre, 1998-2002. Trends in the last 30 years

Between 1998-2002, 16,952 new cases of cancer were registered in Navarre. In men, the most frequently diagnosed cancers were in the following order: prostate, lung, colon and rectum, bladder and stomach, which accounted for 63.2%. In women, the sites were breast, colon and rectum, corpus uteri, stomach and ovary, which accounted for 57.6% of the cases. In the same period, 1998-2002, 4,127 men and 2,470 women died from cancer. Sixty percent of all deaths due to malign tumours in men were due to cancer of the lung, prostate, colon and rectum, stomach and bladder. In women this was due to cancers of colon and rectum, breast, stomach, pancreas and lung, which accounted for 49% of the cases. In men in Navarre there has been an increase in the incidence rates of cancer of the prostate, kidney and non-Hodgkin lymphoma. Avoidable cancers such as those related to smoking (lung, oral cavity and pharynx or pancreas) continue to rise, and represent a greater global risk of dying from cancer in the latest period studied than in the decades of the 1970s and 1980s. From 1995 up to the present, mortality due to cancer has moved from occupying the second place to become the first cause of death among men in Navarre. The global risk of death due to cancer in men is now equal to the first period studied, 1975-1977. Amongst women the global risk of death due to cancer fell by 25% between 1975 and 2002, basically at the cost of breast and stomach cancer. Tumours related to smoking increased both in mortality and in incidence and appear as a significant health problem amongst women in Navarre. Breast cancer has increased in incidence, with lower mortality figures than those of the first period 1975-1977. Invasive cancer of the cervix remains at very low rates in comparison with many European countries, including Spain. In both sexes colorectal and skin cancer has increased, while the incidence and mortality of stomach cancer continues to fall.     

Socioeconomic status and education as risk determinants of gastrointestinal cancer

Standardized incidence ratios were calculated for cancers of the gastrointestinal tract in different socioeconomic and educational groups in Finland. The series constituted all patients with cancers of the esophagus, stomach, colon, rectum, liver (primary only), gallbladder, and pancreas recorded in the Finnish Cancer Registry in 1971-1975 (8,802 cases). Data on socioeconomic status and education were obtained from the records of the national census of December 31, 1970. Cancers of the colon and rectum were associated with high socioeconomic status and higher levels of education, cancers of the esophagus and stomach with lower classes. These associations are most likely to be mediated by dietary habits. No clear-cut association was found for other cancers.     

Meat and Fish Consumption and Cancer in Canada

In this study, we examined the association between meat and fish intake and the risk of various cancers. Mailed questionnaires were completed by 19,732 incident, histologically confirmed cases of cancer of the stomach, colon, rectum, pancreas, lung, breast, ovary, prostate, testis, kidney, bladder, brain, non-Hodgkin's lymphomas (NHL), and leukemia and 5,039 population controls between 1994 and 1997 in 8 Canadian provinces. Measurement included information on socioeconomic status, lifestyle habits, and diet. A 69-item food frequency questionnaire provided data on eating habits 2 yr before data collection. Odds ratios and 95% confidence intervals were derived through unconditional logistic regression. Total meat and processed meat were directly related to the risk of stomach, colon, rectum, pancreas, lung, breast (mainly postmenopausal), prostate, testis, kidney, bladder, and leukemia. Red meat was significantly associated with colon, lung (mainly in men), and bladder cancer. No relation was observed for cancer of the ovary, brain, and NHL. No consistent excess risk emerged for fish and poultry, which were inversely related to the risk of a number of cancer sites. These findings add further evidence that meat, specifically red and processed meat, plays an unfavorable role in the risk of several cancers. Fish and poultry appear to be favorable diet indicators.     

Tea consumption and cancer risk.

The relationship between tea consumption and cancer risk has been analyzed using data from an integrated series of case-control studies conducted in northern Italy between 1983 and 1990. The dataset included 119 histologically confirmed cancers of the oral cavity and pharynx, 294 of the esophagus, 564 of the stomach, 673 of the colon, 406 of the rectum, 258 of the liver, 41 of the gallbladder, 303 of the pancreas, 149 of the larynx, 2,860 of the breast, 567 of the endometrium, 742 of the ovary, 107 of the prostate, 365 of the bladder, 147 of the kidney, 120 of the thyroid, and a total of 6,147 controls admitted to hospital for acute nonneoplastic conditions unrelated to long-term dietary modifications. Multivariate relative risks (RR) for tea consumption were derived after allowance for age, sex, area of residence, education, smoking, and coffee consumption. All the estimates for tea consumption were close to unity, the highest values being 1.4 for rectum, gallbladder, and endometrium. There was no association with cancers of the oral cavity (RR = 0.6), esophagus (RR = 1.0), stomach (RR = 1.0), bladder (RR = 0.8), kidney (RR = 1.1), prostate (RR = 0.9), or any other site considered. Although in northern Italy tea was consumed daily by only a limited proportion of the population, this integrated series of studies offers further reassuring evidence on the relationship between tea and cancer risk.     

Meat and fish consumption and cancer in Canada

In this study, we examined the association between meat and fish intake and the risk of various cancers. Mailed questionnaires were completed by 19,732 incident, histologically confirmed cases of cancer of the stomach, colon, rectum, pancreas, lung, breast, ovary, prostate, testis, kidney, bladder, brain, non-Hodgkin's lymphomas (NHL), and leukemia and 5,039 population controls between 1994 and 1997 in 8 Canadian provinces. Measurement included information on socioeconomic status, lifestyle habits, and diet. A 69-item food frequency questionnaire provided data on eating habits 2 yr before data collection. Odds ratios and 95% confidence intervals were derived through unconditional logistic regression. Total meat and processed meat were directly related to the risk of stomach, colon, rectum, pancreas, lung, breast (mainly postmenopausal), prostate, testis, kidney, bladder, and leukemia. Red meat was significantly associated with colon, lung (mainly in men), and bladder cancer. No relation was observed for cancer of the ovary, brain, and NHL. No consistent excess risk emerged for fish and poultry, which were inversely related to the risk of a number of cancer sites. These findings add further evidence that meat, specifically red and processed meat, plays an unfavorable role in the risk of several cancers. Fish and poultry appear to be favorable diet indicators.     

Incidence and mortality of cancer in Navarra, 1993-1997. Tendencies in the last 25 years

Between 1993-1997, there were 14,023 new cases of cancer registered in Navarra. In men, the most frequently diagnosed cancers were in the following order: lung, prostate, colon and rectum, stomach and bladder, which accounted for 60% of all the cancer cases. In women the sites of breast, colon and rectum, body of uterus, stomach and ovary accounted for 57% of the total number of cases. In the same period, 1993-1997, 3,875 men and 2,332 women died of cancer. 60% of all the deaths caused by malignant tumours in men were due to the sites of lung, colon and rectum, prostate, stomach and bladder. In women the sites of breast, colon and rectum, stomach, pancreas and liver, accounted for 51% of deaths from cancer. Amongst men in Navarra there has been an important increase in the last two decades of the rates of incidence and mortality of cancers related to the habit of smoking (lung, oral cavity and pharynx or pancreas). The global risk of dying from cancer was higher in the late 90s than in the 70s and 80s. From 1995 onwards, cancer mortality advanced from second place to occupy the first place as the cause of death amongst men in Navarra. Amongst women, cardiovascular diseases continue to be the first cause of death. Amongst women the global risk of death from cancer fell by 20% between 1975 and 1997, due principally to a fall in cases of stomach cancer. Tumours related to the habit of smoking have not so far shown substantial increases amongst women in Navarra. Breast cancer has increased in recent years, although its incidence and mortality amongst women in Navarra continues to be somewhat lower than the average in the European Union and the United States. Invasive cervical cancer remains at very low rates with respect to many European countries, including Spain. In both sexes there has been an increase in colorectal cancer and melanoma, while the incidence and mortality of stomach cancer continues to fall.     

Marital status and cancer risk in Italy

BACKGROUND: Marital status has long been related to cancer incidence and mortality rates. However, only few analytical studies have been conducted on this issue considering known or potential confounding factors. METHODS: We systematically examined the relation between marital status and cancer risk using data from a network of case-control studies conducted between 1983 and 2001, including a total of 17,976 incident cases with the following cancer sites: oral cavity and pharynx, esophagus, stomach, colon, rectum, liver, gallbladder, pancreas, larynx, breast, endometrium, ovary, prostate, bladder, kidney, thyroid, Hodgkin's disease, non-Hodgkin's lymphomas, multiple myelomas, and sarcomas. Controls were 15,345 patients admitted to the hospital for non-neoplastic conditions. RESULTS: As compared to married subjects, never married ones were at significantly increased risk of oral cavity and pharyngeal cancers and at reduced risk of cancer of the colon, liver, bladder, kidney, and thyroid. However, for other cancer sites considered, most odds ratios were close to unity. Likewise, there was no consistent excess risk for divorced or widowed subjects. CONCLUSIONS: Despite some significant associations, our study suggests that marital status is not materially associated with cancer risk. Thus, the evidence that married subjects are at lower risk of several other major diseases may not be applicable to cancer.     

Patterns in cancer incidence among American Indians/Alaska Natives, United States, 1992-1999

OBJECTIVE: Cancer is a major public health concern in American Indian and Alaska Native (AI/AN) communities. However, information on the incidence of cancer is lacking for this group. The purpose of this study is to report cancer incidence patterns for the U.S. AI/AN population. METHODS: Age-adjusted annual cancer incidence rates for 1992 through 1999 were calculated for 12 Surveillance, Epidemiology and End Results (SEER) areas, representing a sample (42%) of the U.S. AI/AN population. Trends in cancer incidence rates for the AI/AN sample were determined using standard linear regression of log-transformed rates and were compared to those of the U.S. white population. RESULTS: The top five incident cancers (from highest to lowest) among AI/AN males were prostate, lung and bronchus, colon and rectum, kidney and renal pelvis, and stomach cancers. Among AI/AN women, cancers of the breast, colon and rectum, lung and bronchus, endometrium, and ovary ranked highest. Four sites where cancer incidence rates are greater for AI/ANs than for whites include gallbladder (the AI/AN rate was 4.1 times the rate for white males and 2.6 times the rate for white females), liver and intrahepatic bile duct cancers (1.3 times for males and 2.3 times for females), stomach (1.2 times for males and 1.5 times for females), and kidney and renal pelvis (1.03 times for males and 1.07 times for females). The data show increasing trends for AI/AN males and females and declining trends for white males and females for colorectal, stomach, and pancreatic cancers and leukemia. Similar differences between AI/AN rates and white rates were found for urinary bladder cancers in males and gallbladder cancer in females. CONCLUSIONS: Analysis of SEER data allowed for the determination of disparities in cancer incidence between a sample of the U.S. AI/AN population and the white population. The findings of this study provide baseline information necessary for developing cancer prevention and intervention strategies specific to the AI/AN population to address these cancer disparities.