Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer

1. Download : Download high-res image (257KB)
2. Download : Download full-size image

     

Immune phenotypic linkage between colorectal cancer and liver metastasis

1. Download : Download high-res image (187KB)
2. Download : Download full-size image

     

The landscape of tumor cell states and ecosystems in diffuse large B cell lymphoma

1. Download : Download high-res image (258KB)
2. Download : Download full-size image

     

Single-cell analysis of human non-small cell lung cancer lesions refines tumor classification and patient stratification

1. Download : Download high-res image (201KB)
2. Download : Download full-size image

     

Precise reconstruction of the TME using bulk RNA-seq and a machine learning algorithm trained on artificial transcriptomes

1. Download : Download high-res image (190KB)
2. Download : Download full-size image

     

Apolipoprotein E induces pathogenic senescent-like myeloid cells in prostate cancer

1. Download : Download high-res image (194KB)
2. Download : Download full-size image

     

Simultaneous targeting of TGF-β/PD-L1 synergizes with radiotherapy by reprogramming the tumor microenvironment to overcome immune evasion

1. Download : Download high-res image (240KB)
2. Download : Download full-size image

     

Three subtypes of lung cancer fibroblasts define distinct therapeutic paradigms

1. Download : Download high-res image (132KB)
2. Download : Download full-size image

     

Neutrophil-activating therapy for the treatment of cancer

1. Download : Download high-res image (190KB)
2. Download : Download full-size image

     

The pre-existing T cell landscape determines the response to bispecific T cell engagers in multiple myeloma patients

1. Download : Download high-res image (156KB)
2. Download : Download full-size image

     

Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma

1. Download : Download high-res image (228KB)
2. Download : Download full-size image

     

Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

1. Download : Download high-res image (312KB)
2. Download : Download full-size image

     

Signatures of plasticity,metastasis, and immunosuppression in an atlas of human small cell lung cancer

1. Download : Download high-res image (290KB)
2. Download : Download full-size image

     

Ancestry-driven recalibration of tumor mutational burden and disparate clinical outcomes in response to immune checkpoint inhibitors

1. Download : Download high-res image (189KB)
2. Download : Download full-size image

     

Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation

1. Download : Download high-res image (204KB)
2. Download : Download full-size image

     

Targeting Tumors with IL-10 Prevents Dendritic Cell-Mediated CD8+ T Cell Apoptosis

1. Download : Download high-res image (177KB)
2. Download : Download full-size image

     

Spatiotemporal co-dependency between macrophages and exhausted CD8+ T cells in cancer

1. Download : Download high-res image (137KB)
2. Download : Download full-size image

     

Neutralizing IL-8 potentiates immune checkpoint blockade efficacy for glioma

1. Download : Download high-res image (294KB)
2. Download : Download full-size image

     

Tumor monocyte content predicts immunochemotherapy outcomes in esophageal adenocarcinoma

1. Download : Download high-res image (195KB)
2. Download : Download full-size image

     

Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma

1. Download : Download high-res image (181KB)
2. Download : Download full-size image