共查询到20条相似文献,搜索用时 996 毫秒
1.
Since the late 20th century owing to the improvement of spinal surgery techniques, the diagnosis and treatment of thoracolumbar fracture have been perfected more and more. Although the advent of modern spinal surgery in China was late, we have gained some advanced achievements owing to 相似文献
2.
Benjamin Rohn Daniel Hänggi Nima Etminan Bernd Turowski Hans-Jakob Steiger 《Neurosurgical review》2017,40(1):59-65
Although the benefit of intervention for unruptured arteriovenous malformation (AVM) with regard to stroke rates and long-term disability remains unclear, most patients present with symptoms, such as epilepsy, headache, or neurological deficits, compromising their quality of life. Detailed analysis of the long-term effects of microsurgical treatment on quality of life, epilepsy, and headache was the purpose of this audit. A series of 25 microsurgically treated patients were interviewed on average 7?±?5 years after treatment. Detailed information was obtained regarding frequency and severity of seizures and headaches. Outcome data was compared with the initial complaints and neurological findings. The Short Form (SF)-36 was used to assess health-related quality of life. On average, the SF-36 scores did not differ significantly from the age-matched German norm values. Patients suffering from chronic headache prior to treatment scored worse in most SF-36 subscales than patients without headache at the time of treatment, and the difference was significant in the SF-36 dimensions physical role functioning and emotional role functioning (P?=?0.04). In contrast, there was a trend for patients treated for incidental AVM to score somewhat better than the age norm. Twelve patients had been admitted with epilepsy. At the time of follow-up, all patients were seizure free (Engel class I), although 7 of them continued to take antiepileptic medication. Two of 13 patients without epilepsy at the time of treatment experienced seizures sometime during the post treatment course and were under medication at the time of long-term follow-up interview. At the time of the audit, 7 of 11 patients admitted with chronic headache necessitating regular use of pain medication indicated not to use pain medication any longer. Our data suggest that initial symptoms leading to diagnosis and treatment of unruptured AVM may influence long-term quality of life following treatment. Patients admitted with headache as the chief complaint appear to fare worse than patients with epileptogenic or incidental AVMs. 相似文献
3.
4.
Objective:To observe the morphological characteristics of sacral fracture under different impact loads. Method: Ten fresh pelvic specimens were loaded in dynamic or static state. A series of mechanical parameters including the pressure strain and velocity were recorded. Morphological characteristics were observed under scanning electron microscope. Results: The form of sacral fracture was related to the impact energy. Under low-energy impact loads, ilium fracture, acetabulum fracture and crista iliaca fracture were found. Under high-energy impact loads, three types of sacral fracture occurred according to the classification of Denis: sacral ala fracture, Type I fracture; sacral foramen cataclasm fracture, Type II fracture; central vertebral canal fracture, Type III fracture. Nerve injury of one or two sides was involved in all three types of sacral fracture. The fracture mechanism of sacrum between the dynamic impact and static compression was significantly different. When the impact energy was above 25 J, sacral foramen cataclasm fracture occurred, involving nerve root injury. When it was below 20 J, ilium and sacral fracture was most likely to occur. When it was 20 - 25 J, Type I fracture would occur. While in the static test, most of the fracture belonged to ilium or acetabulum fracture. The cross section of sacrum was crackly and the bone board of Haversian system was brittle, which could lead to separation of bone boards and malposition of a few of cross bone boards. Conclusions: In dynamic state, sacrum fracture mostly belongs to Type I and Type n , and usually involves the nerve roots. Sacrum fracture is relevant to the microstructures, the distribution of the bone trabecula, the osseous lacuna and the Haversian system of sacrum. The fracture of ilium and acetabulum more frequently appears in static state, with slight wound of peripheral tissues. 相似文献
5.
Aim: To study the effect of bisphenol A on the epididymis and epididymal sperm of rats and the possible amelioration action of co-administration with vitamin C. Methods: Male Wistar rats were orally administered bisphenol A (0.2 μg·kg-1·day-1, 2 μg·kg-1·day-1 and 20 μg·kg-1·day-1) and 0.2 μg, 2μg and 20 μg bisphenol A + 40 mg vitamin C·kg-1·day-1 for 60 days. On day 61, rats were killed with anesthetic ether and sperm collected from epididymis were used for assessment of sperm count, motility and viability and biochemical studies. A 1 % homogenate of epididymis was prepared and used for biochemical estimations. Caput, corpus and cauda epididymis were fixed in Bouin's fixative for histological studies. Results: Administration of bisphenol A caused a reduction in the epididymal sperm motility and count and the sperm viability remained unchanged. The activities of superoxide dismutase and glu-tathione peroxidase decreased, while the levels of lipid peroxidation increased in epididymal sperm an 相似文献
6.
Diagnosis and treatment of traumatic hematoma of posterior fossa 总被引:1,自引:0,他引:1
Traumatic hematoma of posterior fossa(THPF) is a special kind of craniocerebral injury with its own characteristics in clinical manifestations, diagnosis and treatment.In general, the prognosis of THPF is poor.Without early diagnosis and prompt treatment, the outcome would be very poor, with high occurrence of morbidity and mortality.Since the availability and mortality.Since the availability of computed tomography(CT)in 1983,we have received and successfully treated 44 patients with THPF until November 2000. 相似文献
7.
8.
Diagnostic and therapeutic management of lumbar and thoracic spondylodiscitis – an evaluation of 59 cases 总被引:2,自引:2,他引:0
Wirtz DC Genius I Wildberger JE Adam G Zilkens KW Niethard FU 《Archives of orthopaedic and trauma surgery》2000,120(5-6):245-251
Fifty-nine patients with spondylodiscitis (SD) of the thoracic and/or lumbar spine were followed-up clinically and radiologically
[X-ray, computed tomography (CT), magnetic resonance imaging (MRI)] over a mean time of 2.2 years (1–6.5 years). All patients
without abscess formation (n = 35) were treated conservatively. Out of the group with abscess formation (n = 24) 6 patients were also treated conservatively, 11 were drained under CT control and 7 were operated. At time of diagnosis,
“signs of florid inflammation” were seen in 60% of the roentgenograms, in 93% of the CTs and in all of the MRIs. The sensitivity
to differentiate between SD with and without abscess formation was 85% by MRI and 69% by CT. “Signs of regressive inflammation”
and “signs of increasing osseous consolidation”, essential facts for starting remobilization, could first be seen using CT
6 weeks after onset of therapy. Using MRI these signs were seen with a considerable delay at 12 weeks. Clinically, only 3
of the 59 analyzed patients developed recurrent SD. In conclusion, MRI is the radiological method of choice for establishing
the diagnosis of SD, in particular with regard to differentiating between cases with and without abscess formations. In contrast,
CT is superior for performing success control after treatment. Therapeutically, conservative, minimal-invasive and operative
procedures are not rival but rather complementary.
Received: 9 May 1999 相似文献
9.
Kriger AG Karmazanovskiĭ GG Kochatkov AV Gorin DS Solodinina EN Kozlov IA Berelavichus SV 《Khirurgiia》2011,(8):24-32
15 patients with intraductal papillary-mucinous tumors (IPMT) of the pancreas were observed. Clinical manifestation corresponded with chronic pancreatitis. Ultrasound study, including endosonography, contrast-enhanced computer and magnetic resonance tomography were used in complex observation of the patients. Dilation of main or lateral pancreatic ducts, connection of tumor with pancreatic duct system and absence of septal calcinosis are typical signs in radiodiagnostics of IPMT. Visualization of parietal papillary proliferations and their contrast enhancement are undeniable signs f or neoplastic character of pancreatic duct dilation. Sensitivity of CT, MRТ and endoUS amounted accordingly 66, 83 and 88%. All patients were operated. Extent of operation was determined by morphological character, localization and size of the tumor (pylorus-preserving pancreaticoduodenal resection was carried out to 6 patients, distal resection including robot-assisted - to 7 patients, midline resection - to 1 patient, duodenum-preserving resection of head and body of pancreas - to 1 patient). Intraoperative urgent histologic study of pancreatic section was carried out by all means. Tumors with borderline degree of malignancy were detected in 4 cases. 相似文献
10.
11.
Background: Ghrelin is a peptide hormone with orexigenic properties, primarily produced by the stomach. Different changes
in fasting ghrelin levels have been reported following bariatric surgery. In this study, we investigate the hypothesis that
because ghrelin is mainly produced by the fundus of the stomach, biliopancreatic diversion with sleeve gastrectomy with total
resection of the gastric fundus and duodenal switch (BPD-DS) will cause substantial decrease in circulating ghrelin levels.
Methods: Serum fasting ghrelin, leptin and adiponectin concentrations were measured by ELISA in 13 patients with morbid obesity
who achieved weight loss by BPD-DS, before the operation and 18 months after. Results: After BPD-DS, BMI decreased significantly,
from 59.15±15.82 kg/m2 to 32.91±6.46 kg/m2 (P=0.001). Serum fasting ghrelin level decreased from 1.44±0.77 ng/ml to 0.99±0.35 ng/ml (P=0.019). Serum leptin level decreased from 1.81±0.38 ng/ml to 1.65±0.32 ng/ml, (P=0.196), and adiponectin level increased from 37.85±11.24 μg/ml to 39.84±16.27 μg/ml (P=0.422). Conclusions: BPD-DS is associated with markedly suppressed ghrelin levels, possibly contributing to the longlasting
weight-reducing effect of the procedure. Leptin levels decreased and adiponectin increased, as expected, after weight loss.
Sleeve gastrectomy with resection of the gastric fundus seems to be the main cause of the postoperative reduction in ghrelin
levels. 相似文献
12.
D. Foschi F. Corsi F. Colombo T. Vago M. Bevilaqua A. Rizzi 《Journal of investigative surgery》2013,26(2):77-81
A decrease in ghrelin plasma levels in morbidly obese patients subjected to bariatric surgery has been considered to help increase body weight loss. Contradictory results have been described after Roux-en-Y gastric bypass (RYGBP), and no study to date has compared RYGBP and vertical banded gastroplasty (VBG), the two main operations performed in the United States. We investigated the effects of RYGBP (10 patients) and VBG (12 patients) on basal and postmeal ghrelin plasma levels in 22 morbidly obese patients (20 F and 2 M), mean age 42.1 ± 3.7 years, mean weight 115 ± 3.9 kg, mean body mass index (BMI) 43.5 ± 1.7. Before surgery and after a 20% reduction in BMI, ghrelin concentrations (pg/mL; radioimmunoassay [RIA], DRG Diagnostics, Germany) were measured in all patients 45 min before and for 3 h after a standard liquid meal (Osmolite RTH solution, 500 mL, 504 kcal). The results were expressed as mean ± SD. Differences between times and groups were evaluated by Student's t-test and one-way analysis of variance (ANOVA). We found that basal ghrelin plasma levels were reduced after RYGBP (to 73.1 ± 6 pg/mL, p <. 05) but increased after VBG (to 172 ± 26 pg/mL, p <. 0009). After a standard liquid meal, ghrelin plasma levels decreased significantly over 1 h in VBG patients, whereas they remained unchanged in RYGBP patients. Since these results were obtained under the same metabolic and anthropometric conditions, we conclude that RYGBP acts through permanent inhibition of ghrelin secretion, whereas VBG merely restores the mechanisms of ghrelin regulation by nutrients. 相似文献
13.
Tatiana Z. Brinckerhoff Sandhya Bondada Catherine E. Lewis Samuel W. French Daniel A. DeUgarte 《Surgery for obesity and related diseases》2013,9(1):108-112
BackgroundAlthough women disproportionately undergo bariatric surgery, the rodent models investigating the mechanisms of bariatric surgery have been limited to males. Female rodent models can also potentially allow us to understand the effects of surgical intervention on future generations of offspring. Sleeve gastrectomy is an attractive weight loss procedure for reproductive-age female patients because it avoids the malabsorption associated with intestinal bypass. We sought to evaluate the effect of sleeve gastrectomy on young female rats with diet-induced obesity at the University of California, Los Angeles, David Geffen School of Medicine.MethodsSprague-Dawley female rats were fed a 60% high-fat diet. At 12 weeks of age, the rats underwent either sleeve gastrectomy or sham surgery. The rats were killed 4 weeks after surgery. A chemistry panel was performed, and the serum adipokines and gut hormones were assayed. The homeostasis model assessment score was calculated. The liver histologic findings were graded for steatosis. The 2-sample t test was used to compare the results between the 2 groups.ResultsSleeve gastrectomy was associated with significant weight loss (5% ± 6% versus ?4% ± 6%; P < .001), lower leptin levels (1.3 ± 1.2 versus 3.5 ± 2.3 ng/mL; P < .01), and higher adiponectin levels (.43 ± .19 versus .17 ± .14 ng/mL; P < .004) compared with the sham-operated rats. No significant differences were found in the fasting ghrelin levels. Furthermore, we did not observe evidence of insulin resistance or steatohepatitis after 11 weeks of high-fat diet. Despite these limitations, additional gender-specific studies are warranted given that most bariatric surgeries are performed in women.ConclusionSleeve gastrectomy appears to result in weight loss and improvements in adiponectin and leptin by way of mechanisms independent of ghrelin levels in a female model of diet-induced obesity. 相似文献
14.
Fasting Plasma Ghrelin Concentrations 6 Months after Gastric Bypass are not Determined by Weight Loss or Changes in Insulinemia 总被引:2,自引:2,他引:0
Frühbeck G Rotellar F Hernández-Lizoain JL Gil MJ Gómez-Ambrosi J Salvador J Cienfuegos JA 《Obesity surgery》2004,14(9):1208-1215
Background: Ghrelin is a gastric peptide with potent orexigenic effects. Circulating ghrelin concentrations are increased
in obese subjects, but increase after weight loss. However, in patients undergoing Roux-en-Y gastric bypass (RYGBP), a decrease
in ghrelin levels has been reported. The effect of comparable weight loss induced by either adjustable gastric banding (AGB),
RYGBP or conventional dietary treatment (Conv) on ghrelinemia was studied. Methods: 24 matched obese male patients in whom
similar weight loss had been achieved by either AGB (n=8), RYGBP (n=8) or Conv (n=8) were studied before and 6 months after
treatment start. The independence of ghrelin concentrations from body mass index (BMI) and weight loss was further analyzed
in a group of patients with total gastrectomy (TtGx, n=6). Results: Comparable weight loss after 6 months exerted significantly
different effects on plasma ghrelin concentrations, depending on the procedure applied (AGB: 424.6 ± 32.8 pg/ml; RYGBP: 131.4
± 13.5; Conv: 457.3 ± 18.7; P<0.001). Without significant differences in body weight and BMI, patients who had undergone the RYGBP exhibited a statistically
significant decrease in fasting ghrelin concentrations, while the other two procedures (AGB and Conv) showed a weight loss-induced
increase in ghrelin levels. Despite significant differences in BMI between RYGBP and TtGx patients after 6 months (31.9 ±
2.2 vs 22.0 ± 0.7 kg/m2, respectively; P<0.05), both groups showed similar ghrelin concentrations. Conclusion: The reduction in circulating ghrelin concentrations
in RYGBP patients after 6 months of surgery are not determined by an active weight loss or an improved insulin-sensitivity
but rather depend on the surgically-induced bypass of the ghrelin-producing cell population of the fundus. 相似文献
15.
《Surgery for obesity and related diseases》2020,16(4):497-502
BackgroundDuring the past years, 2 alternatives to the powerful but side-effect-prone biliopancreatic diversion with duodenal switch (BPD-DS) were developed: one-anastomosis duodenal switch (OADS) and sleeve gastrectomy with transit bipartition (TB).ObjectivesTo compare the 1-year results of TB and BPD-DS aiming at reducing the risk of protein malnutrition while keeping a similar weight loss for body mass index (BMI) ≥50 kg/m2.SettingPrivate hospital, single-surgeon practice in a bariatric surgery center.MethodsAfter a change in practice in 2017, the last 71 primary BPD-DS and the first 71 TB in patients with a BMI ≥50 kg/m2 were retrospectively compared. Postoperative course, side effects, nutritional status, and need for revision and weight outcomes were reviewed. Weight was expressed as BMI, percentage of excess BMI lost, and percentage of total weight lost.ResultsTB was faster to perform (92 versus 149 min, P < .0001) with a comparable 30-day complication rate of 4.3% and 5.7%. TB patients had a shorter hospital stay (2.3 ± 1 versus 4.5 ± 3.4 d, P < .0001). At 1 year, weight loss was significantly lower after TB compared with BPD-DS with percentage of excess BMI loss of 83.7 ± 12.2% versus 78.6 ± 14.7% (P = .0023). Two patients were lost to follow-up after BPD-DS and 6 after TB. Seven BPD-DS patients were treated for protein malnutrition, whereas only 2 patients had severe side effects after TB. Only 7% of the TB patients experienced >3 stools a day compared with 33% after BPD-DS (P = .016). There was no significant difference in terms of co-morbidity improvement at 1 year: 81.8% and 61.9% of patients had remission of blood hypertension, 9% and 14.3% had improvement, type 2 diabetes was in remission in 90% and 88%, and obstructive sleep apnea in 84% and 78% of the TB and BPD-DS patients, respectively.ConclusionsAlthough 1-year weight loss was significantly lower when BMI was ≥50, the real benefit of TB is the reduction of the side effects and protein malnutrition compared with BPD-DS. TB represents a much simpler alternative to BPD-DS for treating superobesity with less risk of major complications, but prospective studies and longer follow-up are required to confirm the maintenance of the weight loss in the long term. 相似文献
16.
Ghrelin: a Gut-Brain Hormone: Effect of Gastric Bypass Surgery 总被引:8,自引:4,他引:4
Background: Ghrelin is a newly recognized gastric hormone with orexigenic and adipogenic properties, produced primarily by
the stomach. Ghrelin is reduced in obesity.Weight loss is associated with an increase in fasting plasma ghrelin. We assessed
the effect of massive weight loss on plasma ghrelin concentrations and its correlation with serum leptin levels and the presence
of type 2 diabetes mellitus (DM) in severely obese patients. Methods: A prospective study was conducted on 28 morbidly obese
women (BMI 56.3±10.2 kg/m2) who underwent gastric bypass, divided into 2 groups: 14 non-diabetics (NGT) and 14 type 2 diabetics (DM2). Ghrelin and leptin
were evaluated before silastic ring transected vertical gastric bypass, and again 12 months postoperatively. Results: Fasting
plasma ghrelin concentrations were 56% lower in NGT and 59% lower in DM2 compared with a lean control group (P<0.001). There was no difference in ghrelin levels between NGT and DM2 groups before and after surgery (P>0.05). Ghrelin was negatively correlated with leptin before gastric bypass surgery (r=0.51, P<0.01). The mean plasma ghrelin concentration decreased significantly after surgery in both groups (P<0.001). Conclusion: Ghrelin was inversely related to leptin concentrations. Presence of diabetes did not affect the ghrelin
pattern. Reduced production of ghrelin after gastric bypass could be partly responsible for the lack of hyperphagia and thus
for the weight loss. 相似文献
17.
Picard Marceau Simon Biron Frédéric-Simon Hould Stéfane Lebel Simon Marceau Odette Lescelleur Laurent Biertho Serge Simard 《Surgery for obesity and related diseases》2009,5(1):43-47
BackgroundThis was a retrospective study, performed 10 years after surgery, to compare the results between biliopancreatic diversion (BPD) with distal gastrectomy (DG) versus BPD with duodenal switch (DS).MethodsComplete follow-up data were available for 96% of patients, allowing a comparison of weight loss, revision, side effects, and complications at 10 years.ResultsAfter BPD-DS, weight loss was 25% greater than after BPD-DG (46.8 ± 21.7 kg versus 37.5 ± 22 kg, respectively; P <.0001). The need for revision decreased from 18.5% to 2.7% (P <.0001), and the prevalence of vomiting during the previous month was 50% less (23.7–50.6%, P <.0001) after BPD-DS compared with after BPD-DG. Late complications were the same for both procedures. Blood analysis showed that, after BPD-DS, the levels of calcium, iron, and hemoglobin were significantly greater and the parathyroid hormone level was lower than after BPD-DG (71.3 ± 44.2 versus 103.0 ± 64.0 ng/L, respectively; P <.0001).ConclusionThe DS greatly improved the BPD, as it was initially proposed. The use of the DS increased weight loss, decreased the need for revision, resulted in fewer side effects, and improved the absorption of nutrients. 相似文献
18.
Foschi D Corsi F Pisoni L Vago T Bevilacqua M Trabucchi A Asti E Trabucchi E 《Obesity surgery》2003,13(6):874-878
Background: Leptin is considered one of the anorectic messengers to the central nervous system in lean subjects. Although
it is secreted by the gastric mucosa, there are contradictory evidences of its involvement in mediating the acute satiety
effect of the meal in obese patients. The effects of restrictive operations on meal-stimulated leptin secretion are unknown.
Methods: The effects of a standard acidified (pH 3) meal on leptin release were investigated in obese patients, before and
after vertical banded gastroplasty (VBG). 8 morbidly obese patients (BMI 49.1±6.5) had serum leptin determination after an
overnight fast. Samples were taken basally and every 30 minutes after the meal for 3 hours. The test was repeated after 20%
BMI reduction. 5 lean volunteers (BMI 22.5±1.7) served as the control group. Results: In obese patients, basal serum leptin
fell from 62±20.4 to 23.8±15.7 ng/ml after the operation (P <0.01) but still with significant differences vs the control group (5.6±3 ng/ml). The meal was associated with a significant
decrease of serum leptin (ANOVA test, P <0.01), and significant differences between obese patients after surgery and lean subjects were found. Conclusion: Serum
leptin was reduced by the meal in obese patients and VBG did not attain satiety through serum leptin changes. 相似文献
19.
Background:This study observes the effect of surgical weight loss on free radical and antioxidant vitamin balance. Patients
and Methods: 22 consecutive morbidly obese patients undergoing vertical banded gastroplasty (VBG) were chosen for the study.
Postoperative studies were done at 12 and 24 weeks. Plasma antioxidant and vitamin determinations were performed by HPLC method.
Results: Subjects lost a significant amount of weight (P<0.01). Compared to preoperative measurements, postoperative measurements of plasma betacarotene were not statististically
different both at 12 and 24 weeks (13.86±1.26 μg/dl, 12.35±1.2, P=0.44; 14.33±2.03, P=0.77; preoperatively, 12 and 24 weeks respectively). Alpha-tocopherol increased slightly at the 12th week; the difference
was not significant (8.50±0.77; 9.56±0.82, P=0.37; preoperatively and 12th week respectively). The levels of alpha-tocopherol rose at 24th week significantly (10.89±0.55,
P=0.028). The indicator of lipid peroxidation (malondialdehyde) decreased with weight loss (1.505±0.11 μmol/L preoperatively;
0.75±0.062 at 12th week, P=0.01; 0.712±0.05 at 24th week, P<0.01). Conclusion: Our data show that free radical generation falls markedly in association with weight loss after VBG. Surgical
weight loss leads to significant decrease in oxidant production and also leads to increase in some antioxidant vitamins. The
demon stration of decreased free radical generation and correction of balance between free radicals and antioxidant vitamins
has important implications for oxidative mechanisms underlying obesity-associated disorders. 相似文献
20.
Sleeve Gastrectomy and Gastric Banding: Effects on Plasma Ghrelin Levels 总被引:17,自引:1,他引:16
Langer FB Reza Hoda MA Bohdjalian A Felberbauer FX Zacherl J Wenzl E Schindler K Luger A Ludvik B Prager G 《Obesity surgery》2005,15(7):1024-1029
Background: Different changes of plasma ghrelin levels have been reported following gastric banding, Roux-en-Y gastric bypass,
and biliopancreatic diversion. Methods: This prospective study compares plasma ghrelin levels and weight loss following laparoscopic
sleeve gastrectomy (LSG) and laparoscopic adjustable gastric banding (LAGB) in 20 patients. Results: Patients who underwent
LSG (n=10) showed a significant decrease of plasma ghrelin at day 1 compared to preoperative values (35.8 ± 12.3 fmol/ml vs
109.6 ± 32.6 fmol/ml, P=0.005). Plasma ghrelin remained low and stable at 1 and 6 months postoperatively. In contrast, no change of plasma ghrelin
at day 1 (71.8 ± 35.3 fmol/ml vs 73.7 ± 24.8 fmol/ml, P=0.441) was found in patients after LAGB (n=10). Increased plasma ghrelin levels compared with the preoperative levels at
1 (101.9 ± 30.3 fmol/ml vs 73.7 ± 24.8 fmol/ml, P=0.028) and 6 months (104.9 ± 51.1 fmol/ml vs 73.7 ± 24.8 fmol/ml, P=0.012) after surgery were observed. Mean excess weight loss was higher in the LSG group at 1 (30 ± 13% vs 17 ± 7%, P=0.005) and 6 months (61 ± 16% vs 29 ± 11%, P=0.001) compared with the LAGB group. Conclusions: As a consequence of resection of the gastric fundus, the predominant area
of human ghrelin production, ghrelin is significantly reduced after LSG but not after LAGB. This reduction remains stable
at follow-up 6 months postoperatively, which may contribute to the superior weight loss when compared with LAGB. 相似文献