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1.
目的探讨采用弹簧圈栓塞动脉瘤及载瘤动脉治疗出血性椎动脉夹层动脉瘤的疗效及并发症。方法收集经颅脑CT及全脑DSA确诊的椎动脉夹层动脉瘤破裂出血患者17例,采用弹簧圈栓塞动脉瘤及载瘤动脉,观察疗效及并发症。结果 17例动脉瘤及载瘤动脉均完全闭塞,无死亡病例。术后当天1例发生Wallenberg综合征,恢复良好;1例术后3个月出现脑积水,行侧脑室-腹腔分流术后遗留轻度残疾;随访2~36个月,无再出血病例。术后6个月12例接受DSA复查,动脉瘤完全不显影,载瘤动脉未发生再通。结论应用弹簧圈栓塞夹层动脉瘤及载瘤动脉治疗出血性椎动脉夹层动脉瘤疗效确切,具有一定应用价值。  相似文献   

2.
支架植入术联合弹簧圈栓塞治疗颅内复杂动脉瘤   总被引:5,自引:4,他引:1  
目的探讨应用新型颅内支架植入联合弹簧圈栓塞术治疗颅内复杂动脉瘤的疗效。方法对26例30个颅内复杂动脉瘤行支架植入术弹簧圈栓塞术,术后6~24个月进行随访。结果术后即刻疗效:24个复杂动脉瘤完全栓塞,4个次全栓塞(栓塞95%以上),2个不完全栓塞;所有支架位置满意,载瘤动脉通畅。随访2例动脉瘤复发,未见支架移位、塌陷、狭窄,载瘤动脉通畅、光滑。结论颅内支架植入联合弹簧圈栓塞术治疗颅内复杂动脉瘤安全有效;应根据动脉瘤的具体情况来选择具体技术。  相似文献   

3.
李吻  陈晟 《浙江创伤外科》2014,(6):1019-1020
目的:探讨外伤性鼻衄的血管内介入栓塞治疗的策略和疗效。方法对10例行血管内介入栓塞治疗的外伤性鼻衄患者的临床资料进行了回顾性分析。结果全部病例均行脑血管造影检查,3例为颈内动脉海绵窦段破裂,其中两例脑血管造影为颈内动脉海绵窦段假性动脉瘤,采用弹簧圈栓塞破口、假性动脉瘤及闭塞同侧载瘤动脉,3例一次性栓塞破口、假性动脉瘤及载瘤动脉;7例为颈外动脉颌内动脉分支破裂,4例采用明胶海绵颗粒栓塞颌内动脉,即刻造影见颌内动脉远端不显影,3例采用弹簧圈栓塞颌内动脉,其中2例即刻造影弹簧圈远端破口不显影,1例颌内动脉破口大部分消失,同侧面动脉通过远端分支动脉向破口少量供血,2周后脑血管造影随访提示破口完全消失。6例随访3个月至2年,平均1.5年,无再出血及神经功能障碍。结论血管内介入治疗外伤性鼻衄是一种安全、微创和有效的治疗方法,外伤性鼻衄应尽早进行介入栓塞治疗。  相似文献   

4.
目的 观察支架辅助弹簧圈栓塞治疗大脑中动脉分叉部宽颈动脉瘤的安全性和有效性。方法 分析60例接受支架辅助弹簧圈栓塞治疗的大脑中动脉分叉部宽颈动脉瘤患者共65个动脉瘤,观察术后即刻及随访动脉瘤栓塞程度,评估术后并发症、疗效及安全性。结果 术中2例(2/60,3.33%)动脉瘤破裂出血,4例(4/60,6.67%)支架内血栓形成;术后即刻栓塞程度为Raymond Ⅰ级50个(50/65,76.92%)、Ⅱ级12个(12/65,18.46%)、Ⅲ级3个(3/65,4.62%)。术后1个月内3例(3/60,5.00%)动脉瘤再出血,2例致死;1例(1/60,1.67%)死于肺栓塞;4例(4/60,6.67%)并发脑梗死。1例术后6个月瘤颈复发,1例术后25个月出现无症状性血管闭塞;末次复查数字减影血管造影显示43个(43/51,84.31%) RaymondⅠ级、8个(8/51,15.69%)Ⅱ级。末次随访,49例(49/57,85.96%)改良Rankin量表评分为0~2分,8例(8/57,14.04%)为3~4分。结论 支架辅助弹簧圈栓塞技术治疗大脑中动脉宽颈动脉瘤安全、有效。  相似文献   

5.
动脉瘤模型栓塞前后血流动力学对比研究   总被引:2,自引:1,他引:1  
目的 评价动脉瘤模型行腔内微弹簧圈栓塞前后血流动力学的改变,用以判断疗效。方法 运用改进的显微外科技术建立犬颈总动脉(CCA)动脉瘤模型22个,其中侧壁型12个,分叉部4个,末端型6个。术后7~14d行彩色多普勒超声、经颅多普勒(TCD)、数字减影动脉血管造影(IADSA)及经微导管动脉瘤内测压,然后以微弹簧圈紧密填塞动脉瘤腔,栓塞后重复进行上述检查,比较栓塞前后血流动力学变化。结果 所建模型均获成功。实验证实,动脉瘤微弹簧圈栓塞前后其血流动力学参数的差异有统计学意义(P〈0.01)。结论 实验所建动物模型是研究动脉瘤血管内栓塞治疗的理想方法;动脉瘤微弹簧圈栓塞后,能减低、改变或消除载瘤动脉及动脉瘤内异常血流动力学状态,终止动脉瘤行为,防止动脉瘤扩大和破裂。  相似文献   

6.
动脉瘤模型栓塞前后血流动力学的改变   总被引:3,自引:1,他引:2  
目的评价动脉瘤模型行腔内微弹簧圈栓塞前后血流动力学的改变,用以判断疗效。方法运用改进的显微外科技术建立犬颈总动脉(CCA)动脉瘤模型22个,其中侧壁型12个。分叉部4个,末端型6个。术后7~14d行彩色多普勒超声、经颅多普勒(TCD)、数字减影动脉血管造影(IADSA)及经微导管动脉瘤内测压,然后以微弹簧圈紧密填塞动脉瘤腔,栓塞后重复进行上述检查,比较栓塞前后血流动力学变化。结果所建模型均获成功。实验证实,动脉瘤微弹簧圈栓塞前后其血流动力学参数的差异有统计学意义(P〈0.01)。结论实验所建动物模型是研究动脉瘤血管内栓塞治疗的理想方法;动脉瘤微弹簧圈栓塞后,能减低、改变或消除载瘤动脉及动脉瘤内异常血流动力学状态,终止动脉瘤行为,防止动脉瘤扩大和破裂。  相似文献   

7.
目的总结血管腔内介入治疗腹腔内脏动脉瘤(Visceral artery aneurysms,VAA)的方法及临床效果。方法选取2015年1月至2020年1月确诊为VAA病例,采用保守治疗、单纯栓塞、瘤腔栓塞联合载瘤动脉栓塞、覆膜支架置入、裸支架+弹簧圈瘤腔内栓塞术式对不同类型的VAA进行治疗,统计其术后疗效。结果全组病人顺利完成治疗,无死亡病例,1次栓塞成功率(92.16%,47/51),2次成功率100%。14例保守治疗,随访期间无动脉瘤增大;6例行单纯弹簧圈栓塞、36例行载瘤动脉远近端栓塞或瘤腔栓塞联合载瘤动脉栓塞术、覆膜支架植入术7例、裸支架+弹簧圈瘤腔内栓塞术2例,治疗效果满意。结论 EVT治疗VAA具有创伤小、麻醉风险低、术后快速康复的优势,但应根据具体病情选择合适的治疗方法。  相似文献   

8.
目的观察血管内介入治疗大脑后动脉夹层动脉瘤的效果。方法回顾性分析12例接受血管内介入治疗的大脑后动脉夹层动脉瘤患者,评价治疗效果。结果12例大脑后动脉夹层动脉瘤中,P1段2例,P1-P2段2例,P2段6例,P3段2例,均成功实施栓塞治疗;对其中2例单纯以弹簧圈栓塞动脉瘤,8例以弹簧圈闭塞载瘤动脉,2例植入支架。术后即刻行复查造影显示Raymond分级1级10例,2级2例。术后4例诉头痛,经对症治疗后2周内好转;未见动脉瘤破裂出血及脑梗死。随访期间影像学检查均未见动脉瘤复发,无新发神经功能障碍及颅内再次出血;末次随访时改良Rankin量表0分10例,1分1例,2分1例。结论血管内介入治疗大脑后动脉夹层动脉瘤效果较好,且安全性较高。  相似文献   

9.
目的探讨血管腔内治疗脾动脉瘤的安全性和有效性。方法回顾性分析2010年1月至2014年12月本科收治的48例脾动脉瘤患者的资料,腔内治疗方法:弹簧圈动脉瘤(14例)或载瘤动脉栓塞术(19例),覆膜支架隔绝术(2例),支架辅助弹簧圈瘤体内填塞(5例)和多层裸支架隔绝术(8例)。术后1、3、6、12个月采用CT血管造影检查随访,记录并评价围手术期和随访期的临床结果指标。结果本组病例瘤体均治疗成功,支架植入患者的脾动脉均通畅。围手术期无手术相关死亡,8例患者弹簧圈栓塞后出现栓塞后综合征,均于3~5天后缓解。随访时间23.9(3~59)个月,采用弹簧圈栓塞瘤体或载瘤动脉33例:4例患者发现有部分脾脏梗死,但无明显临床症状,2例患者因瘤体内再灌注接受再次手术;采用覆膜支架植入或裸支架辅助弹簧圈栓塞7例:动脉瘤隔绝或栓塞良好,无内漏,支架通畅;采用多层裸支架隔绝术8例:术后12个月6例(75%)患者瘤腔达到完全血栓化,分支动脉通畅。其余病例未出现严重并发症。随访期患者均未观察到动脉瘤增大、破裂或复发。结论血管腔内治疗脾动脉瘤安全,疗效显著。  相似文献   

10.
肾动脉瘤的血管腔内治疗   总被引:1,自引:1,他引:0  
目的评价血管腔内治疗对于肾动脉瘤(RAA)的安全性及疗效。方法回顾性分析11例接受血管腔内治疗的RAA患者,治疗方法包括单纯以弹簧圈填塞动脉瘤腔(6例)、载瘤动脉栓塞术(3例)和覆膜支架隔绝术(2例),并随访3~68个月。结果11例患者共发现13个RAA(右肾9个,左肾4个),均为真性囊状动脉瘤,对其中11例(11个RAA)行血管腔内治疗。术后5例出现栓塞后综合征,其中4例发生部分肾梗死,肾功能无异常;未见其他严重并发症。随访未见动脉瘤内残腔及内瘘,未见动脉瘤破裂及复发。结论血管腔内治疗RAA安全、有效,成功率高。  相似文献   

11.
We experienced nine cases of intracranial aneurysms which were treated with three-dimensional Guglielmi detachable coils (3D-GDC). 3D-GDC is useful in the construction of the initial frame for the embolization of aneurysms, but it also has certain disadvantages for achieving successful treatment. Nine patients with nine intracranial aneurysms were treated with 3D-GDC for initial framing from October, 1999 to September, 2000 at the National Cardio-Vascular Center, Japan. Angiographically complete and successful occlusion was performed in only three patients. Four patients developed parent artery stenosis due to small loops of the 3D-GDC protruding from the aneurysm. Two patients experienced incomplete occlusion because small loops of the 3D-GDC caused cells to form in the framing, and additional coils could not be inserted into some cells. 3D-GDC is useful as an initial framing coil, but we should be careful when placing additional coils into an aneurysm because we cannot predict the effect of the small loops of 3D-GDC on the embolization of aneurysms.  相似文献   

12.
Irie K  Kawanishi M  Nagao S 《Neurologia medico-chirurgica》2000,40(12):603-8; discussion 608-9
Endovascular treatment of wide-necked cerebral aneurysms with Guglielmi detachable coils (GDCs) has been limited due to coil protrusion into the artery. Seven patients with wide-necked cerebral aneurysms were treated with GDCs with temporary balloon inflation for mechanical protection during coil placement. Transarterial embolization of the aneurysm with GDCs had failed due to coil protrusion into the parent artery. The use of simultaneous temporary balloon protection achieved more dense intra-aneurysmal coil packing, especially in the neck, without compromising the parent artery.  相似文献   

13.
We describe a case of the combined application of endovascular stent implantation and Guglielmi detachable coil packing for the treatment of a vertebro-basilar fusiform aneurysm and review the literature on stent placement to treat cerebral aneurysms. A 70-year-old female presented with an acute headache from subarachnoid hemorrhage. A fusiform aneurysm with a broad-based neck and dome, measuring 15 mm, involving the union of the vertebral arteries and the proximal basilar artery was demonstrated on cerebral angiography. The aneurysm was judged to be inoperable and treated conservatively. Twelve days later the patient was transferred to our hospital for endovascular therapy. An intravascular stent (MultiLink) was placed across the base of the aneurysm through the right vertebral artery. After this, coil placement in the aneurysm around the stent was performed via a microcatheter guided from the left vertebral artery. After that a microcatheter was guided from the right vertebral artery through the interstices of the stent into the aneurysm, and additional coils were placed. Final angiography showed subtotal occlusion of the aneurysm and excellent blood flow of the parent artery through the stent. There were no new neurological deficits. Neither rerupture nor ischemic event has occurred. The use of stents provides another treatment for managing the difficult entity of intracranial aneurysms.  相似文献   

14.
A 61-year-old woman suffered cisternal coil migration in the follow-up period after endovascular coil embolization for a ruptured cerebral aneurysm. She presented with sudden onset of headache. Computed tomography demonstrated diffuse subarachnoid hemorrhage, and cerebral angiography disclosed a left anterior choroidal artery aneurysm. The aneurysm was treated by endovascular embolization with Guglielmi detachable coils. During the embolization procedure, the microcatheter perforated the aneurysm. For direct closure of the perforation site with coils, the microcatheter was withdrawn and coils were deployed partially in the subarachnoid space and partially in the aneurysm sac. The coil mass was spread in the subarachnoid space around the aneurysm immediately after embolization. The patient was discharged with no neurological deficit. Three months later, follow-up radiography demonstrated obvious reduction in the size and compaction of the coil mass. Magnetic resonance angiography and digital subtraction angiography demonstrated stable occlusion of the aneurysm. The coil mass probably spread in the cistern around the aneurysm and was compacted by the shape memory of the coils and pulsation of the brain and vessels, as the subarachnoid clots around the aneurysm had disappeared. This case suggests that cisternal coil migration should be considered in the follow up of intracranial aneurysm treated with detachable coils.  相似文献   

15.
MacKay CI  Han PP  Albuquerque FC  McDougall CG 《Neurosurgery》2003,53(3):754-9; discussion 760-1
OBJECTIVE AND IMPORTANCE: Dissecting aneurysms of the intracranial vertebral artery are increasingly recognized as a cause of subarachnoid hemorrhage. We present a case involving technical success of the stent-supported coil embolization but with recurrence of the dissecting pseudoaneurysm of the intracranial vertebral artery. The implications for the endovascular management of ruptured dissecting pseudoaneurysms of the intracranial vertebral artery are discussed. CLINICAL PRESENTATION: A 36-year-old man with a remote history of head injury had recovered functionally to the point of independent living. He experienced the spontaneous onset of severe head and neck pain, which progressed rapidly to obtundation. A computed tomographic scan of the head revealed subarachnoid hemorrhage centered in the posterior fossa. The patient underwent cerebral angiography, which revealed dilation of the distal left vertebral artery consistent with a dissecting pseudoaneurysm. INTERVENTION: Transfemoral access was achieved under general anesthesia, and two overlapping stents (3 mm in diameter and 14 mm long) were placed to cover the entire dissected segment. Follow-up angiography of the left vertebral artery showed the placement of the stents across the neck of the aneurysm; coil placement was satisfactory, with no residual aneurysm filling. Approximately 6 weeks after the patient's initial presentation, he developed the sudden onset of severe neck pain. A computed tomographic scan showed no subarachnoid hemorrhage, but computed tomographic angiography revealed that the previously treated left vertebral artery aneurysm had recurred. Angiography confirmed a recurrent pseudoaneurysm around the previously placed Guglielmi detachable coils. A test balloon occlusion was performed for 30 minutes. The patient's neurological examination was stable throughout the test occlusion period. Guglielmi detachable coil embolization of the left vertebral artery was then performed, sacrificing the artery at the level of the dissection. After the procedure was completed, no new neurological deficits occurred. On the second day after the procedure, the patient was discharged from the hospital. He was alert, oriented, and able to walk. CONCLUSION: We appreciate the value of preserving a parent vessel when a dissecting pseudoaneurysm of the intracranial vertebral artery ruptures in patients with inadequate collateral blood flow, in patients with disease involving the contralateral vertebral artery, or in patients with both. However, our case represents a cautionary note that patients treated in this fashion require close clinical follow-up. We suggest that parent vessel occlusion be considered the first option for treatment in patients who will tolerate sacrifice of the parent vessel along its diseased segment. In the future, covered stent technology may resolve this dilemma for many of these patients.  相似文献   

16.
Wong GK  Yu SC  Poon WS 《Surgical neurology》2007,67(2):122-6; discussion 126
BACKGROUND: Aneurysm recurrence is an innate problem in endovascular treatment of aneurysms with coils. A coated coil system named Matrix (Boston Scientific Neurovascular, Fremont, CA), covered with a bioabsorbable polymeric material (polyglycolide/lactide copolymer [PGLA]), was developed to accelerate intraaneurysmal clot organization and fibrosis. The purpose of this study was to evaluate the efficacy and safety of the Matrix detachable coils in patients with intracranial aneurysms and aneurysmal recurrence rate. METHODS: In a regional neurosurgical center in Hong Kong, data of patients undergoing endovascular embolization of intracranial aneurysm was collected. In a 20-month period, 42 patients with 44 aneurysms were treated by endovascular embolization using matrix coils alone or mixed with bare platinum coils. Thirty-four patients presented with ruptured aneurysms, and 8 patients presented with unruptured aneurysms. RESULTS: Twenty-five patients (60%) had 6-month follow-up DSA, and 10 patients (24%) had 18-month follow-up DSA. Seven aneurysm recurrences were identified, amounting to 16% for all aneurysms and 14% for ruptured aneurysms. Four patients were treated by repeated embolization, and 2 patients were treated by microsurgical clipping. Two adverse events due to thromboembolism were noted. One 78-year-old lady with poor-grade subarachnoid hemorrhage treated by partial embolization died from rebleed at day 4. Another patient with partial embolization and spontaneous thrombosis of dorsal wall ICA aneurysm died at 2 months with aneurysm recanalization with rerupture. Twenty-six patients achieved favorable outcome (GOS score 4 or 5) at last follow-up. The aneurysm recurrence rate using bare platinum coils of the same center was 11% and 7% for all aneurysms and ruptured aneurysms, respectively. CONCLUSION: Matrix coil embolization was safe, but there was no reduction in aneurysm recurrence using matrix coils alone or mixed with GDCs, compared with GDCs alone.  相似文献   

17.
Alexander MJ  Duckwiler GR  Gobin YP  Viñuela F 《Neurosurgery》2002,50(4):899-901; discussion 901-2
OBJECTIVE AND IMPORTANCE: Thromboembolic complications after cerebral aneurysm treatment with Guglielmi detachable coils (Boston Scientific/Target, Fremont, CA) are not infrequent; in a University of California, Los Angeles institutional review of 720 treated aneurysms, thromboembolic complications occurred in 2.5% of cases. The development of intraluminal thrombus during the embolization procedure, however, may be diagnosed promptly and treated effectively with appropriate therapy. This report describes the use of intravenously administered abciximab for the treatment of intraprocedural arterial thrombus encountered during the coil embolization of a recently ruptured anterior communicating artery aneurysm. CLINICAL PRESENTATION: A 45-year-old man presented with severe headache 12 days before transfer to our institution. He had no neurological deficits at admission. Previous computed tomography of the brain demonstrated subarachnoid hemorrhage, and magnetic resonance angiography from the other institution demonstrated a 4-mm anterior communicating artery aneurysm. INTERVENTION: The patient underwent Guglielmi detachable coil embolization of the aneurysm under systemic heparinization. During the embolization, however, a thrombus developed in the proximal left A2 segment. The patient was given an intravenous infusion (20 mg) of abciximab for 10 minutes, and within 15 minutes dissolution of the thrombus was observed with no angiographic evidence of distal emboli. After reversal of general anesthesia, the patient exhibited minimal right leg weakness, which resolved within 1 hour. CONCLUSION: Abciximab may be a useful adjunct for endovascular treatment of patients with cerebral aneurysms in whom intraprocedural arterial thrombus is encountered.  相似文献   

18.
Among 121 intracerebral aneurysms presenting at one institution between 1984 and 1989, 16 were treated by endovascular means. All 16 lesions were intradural and intracranial, and had failed either surgical or endovascular attempts at selective exclusion with parent vessel preservation. The lesions included four giant middle cerebral artery (MCA) aneurysms, one giant anterior communicating artery aneurysm, six giant posterior cerebral artery aneurysms, one posterior inferior cerebellar artery aneurysm, one giant mid-basilar artery aneurysm, two giant fusiform basilar artery aneurysms, and one dissecting vertebral artery aneurysm. One of the 16 patients failed an MCA test occlusion and was approached surgically after attempted endovascular selective occlusion. Treatment involved pretreatment evaluation of cerebral blood flow followed by a preliminary parent vessel test occlusion under neuroleptic analgesia with vigilant neurological monitoring. If the test occlusion was tolerated, it was immediately followed by permanent occlusion of the parent vessel with either detachable or nondetachable balloon or coils. The follow-up period ranged from 1 to 8 years. Excellent outcomes were obtained in 12 cases with complete angiographic obliteration of the aneurysm and no new neurological deficits and/or improvement of the preembolization symptoms. Four patients died: two related to the procedure, one secondary to rupture of another untreated aneurysm, and the fourth from a postoperative MCA thrombosis after having failed endovascular test occlusion. The angiographic, clinical, and cerebral blood flow criteria for occlusion tolerance are discussed.  相似文献   

19.
OBJECTIVE AND IMPORTANCE: Despite recent advances in technology, parent vessel coil herniation occasionally complicates successful Guglielmi detachable coil embolization, particularly in wide-necked aneurysms. We report endovascular stent deployment performed in two patients specifically to treat this complication. CLINICAL PRESENTATION: Two patients underwent Guglielmi detachable coil embolization of cavernous segment aneurysms. Both developed coil herniation into the internal carotid artery. In one patient, the herniation occurred during the initial procedure; in the other, it was discovered in a delayed fashion during a follow-up examination for ocular symptoms. INTERVENTION: In both patients, endovascular stent deployment was performed to isolate the herniated portion of the coil from the internal carotid lumen. Follow-up angiography at 6 months demonstrated no aneurysm recanalization and no stenosis of the parent internal carotid artery in the stented region in either patient. CONCLUSION: The use of intraluminal stents has been reported to be a helpful technical adjunct to the conventional endovascular treatment of aneurysms and balloon angioplasty. One additional indication for the use of this technology is sequestering herniated coils from the lumen of the parent artery to reduce potential embolic or occlusive sequelae.  相似文献   

20.
Objective: This was a retrospective review of the results using stent‐assisted coil embolization for management of intracranial aneurysms. Methods: The records of seven patients treated with stent‐assisted Gugliemi detachable coil (GDC) embolization were retrieved from the authors’ prospectively maintained database. The clinical presentation, site and type of aneurysms, treatment procedure and complications, and outcome of these identified cases were reviewed. Results: Between January 2002 and May 2004, seven patients with intracranial aneurysms, four of which were ruptured, were treated by stent‐assisted GDC embolization. Four aneurysms were located at the anterior circulation and three were at the posterior circulation. The indications for stent use were: giant aneurysm (>2.5 cm), dissecting pseudo‐aneurysm, broad‐necked aneurysm and the need for preservation of important parent arteries or branches. Concerning the technical aspect, all except one had successful stent deployment. One stent dislodged after apparent successful deployment. GDC embolization was continued and the aneurysm was partially occluded. More than 90% occlusion of aneurysm sac was achieved in six aneurysms. Intraoperative complications included over‐coagulation, failure in stent deployment, displacement of stent, coil entrapment and thromboembolism. One patient had added focal neurological deficit after the procedure, and one became vegetative due to an unrelated cause. The patient in whom the stent was dislodged suffered another subarachnoid haemorrhage 4 months later and died. Conclusion: Percutaneous intracranial stent is a new and useful device to assist embolization of cerebral aneurysms that were previously not amenable to endovascular therapy. These preliminary results suggest that this procedure could achieve satisfactory outcomes without significant complications.  相似文献   

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