腹腔镜治疗青年十二指肠球溃疡穿孔的临床应用

目的 评价腹腔镜下修补治疗十二指肠球部前壁溃疡穿孔的临床应用价值。方法 对我院2003年1月～2004年12月收治的42例青年十二指肠溃疡穿孔病例随机分组，20例接受腹腔镜下修补治疗，22例接受传统开腹修补。结果 两组术后胃肠功能恢复情况、术后使用镇痛药、平均住院时间差异均有显著性（P〈0．05），两组术后均无出血、中转开腹、再穿孔等并发症。结论 腹腔镜下修补治疗青年十二指肠球部前壁溃疡穿孔临床安全可行，应该作为首选方法在临床上推广应用。     

腹腔镜胃十二指肠溃疡穿孔修补术13例临床体会

目的 腹腔镜急性胃、十二指肠溃疡穿孔修补术的临床经验.方法 2003年6月～2007年12月,对13例急性胃、十二指肠溃疡穿孔患者施行腹腔镜溃疡穿孔修补术.结果 13例中十二指肠球部溃疡穿孔5例,幽门管溃疡1例,胃窦部溃疡穿孔7例,穿孔直径为0.3～0.7 cm,腹腔内积液600～1200 mL.手术时间80～180 min,除1例病检胃癌,改开放手术外,其余12例手术均获成功,术后恢复顺利,切口甲级愈合10例,乙级愈合2例.住院天数7～10 d.随访1年,胃镜检查溃疡均愈合,无再穿孔、腹腔感染、肠粘连、肠梗阻等并发症发生.结论 腹腔镜手术治疗急性胃、十二指肠溃疡穿孔,与开腹手术同样安全且有效.胃溃疡穿孔患者术中需快速病理检查,若为恶性病变应中转开腹.     

腹腔镜与开腹胃十二指肠溃疡穿孔修补的临床对比研究

[摘要]目的探讨腹腔镜修补术治疗胃十二指肠溃疡穿孔的临床效果和优势。方法收集我院2007年3月至2012年12月问用腹腔镜行胃十二指肠溃疡穿孔修补术的28例临床资料,并将其与同期行开腹穿孔修补的32例病例进行回顾性病例对照研究。结果腹腔镜与开腹手术相比,手术时间、切口感染率和腹腔积液感染率差异无统计学意义（P〉0．05）。但腹腔镜术中出血量、术后胃肠功能恢复时间、住院时间、镇痛剂使用率等指标均显著优于开腹组（P〈0．01）。对两组患者进行随访,平均随访时间为15（3—28）个月,经胃镜检查均未见溃疡复发。结论腹腔镜治疗胃十二指肠溃疡穿孔安全有效,具有侵袭性小、腹腔干扰小、术后痛苦小、肠功能恢复快、住院时间短等优点。     

腹腔镜与开腹胃十二指肠穿孔修补术的临床对比

目的探讨腹腔镜胃十二指肠穿孔修补术安全性和可行性。方法对2010年01月至2012年12月行手术治疗的56例胃十二指肠溃疡穿孔的患者的临床资料,排除癌性穿孔5例,其中腹腔镜手术24例,开腹手术27例,比较两组不同治疗后的效果情况。结果两组患者均顺利完成手术,腹腔镜组无中转开腹病例。腹腔镜组平均手术时间、平均手术出血量差异无统计学意义（P=0．204,P=0．551）。腹腔组术后初次下床活动时间、术后住院时间、术后通气时间均小于开腹组,差异具有统计学意义（P=0．039,P=0．001,P=0．021）。比较两组术后并发症发生率差异无统计学意义（P=0．884）。结论腹腔镜胃十二指肠穿孔修补术一种安全而可行的手术方式。     

腹腔镜治疗胃十二指肠溃疡穿孔11例体会

探讨腹腔镜胃、十二指肠溃疡穿孔修补手术方法、适应证及优缺点。对11例胃、十二指肠溃疡穿孔行腹腔镜修补术，其中胃溃疡穿孔3例、十二指肠穿孔8例。结果 示腹腔镜下完成手术8例、中转开腹3例。腹腔镜胃、十二指肠溃疡穿孔修补术创伤小，术后恢复时间短，安全性高，费用较低，有推广价值。     

腹腔镜与开腹手术用于胃十二指肠溃疡穿孔修补术的疗效及医疗费用比较

目的对比分析腹腔镜与开腹手术修补胃十二指肠溃疡穿孔在手术疗效和医疗费用方面的差异。方法将我院2003年5月～2008年5月急诊行消化性溃疡穿孔修补术的62例分为腹腔镜手术组（28例）和开腹手术组（34例），比较两组的临床疗效和医疗费用指标。结果腹腔镜手术组在手术时间、术中出血量、术后第2d白细胞计数、病人术后肛门排气时间、切口感染情况、住院时间、住院费用等方面均显著低于开腹手术组（P〈0．05）；而术后镇痛药使用例次腹腔镜手术组与开腹手术组相比较，有非常显著性差异（P〈0．01）。结论腹腔镜下行胃十二指肠溃疡穿孔修补术在手术疗效及医疗费用方面均优于开腹手术者。     

全程优化、网膜填塞法在腹腔镜急性上消化道穿孔修补术中的应用(附98例报告)

目的:探讨全程优化、网膜填塞法用于腹腔镜上消化道穿孔修补术的可行性,总结临床经验。方法:回顾分析98例腹腔镜胃十二指肠溃疡穿孔修补术的临床资料,其中十二指肠球部溃疡穿孔30例,胃窦部前壁穿孔68例。结果:本组98例均获成功,无中转开腹。穿孔直径0.3~3.5 cm,平均(0.77±0.52)cm。手术时间45~200 min,平均(87.35±32.10)min,术中出血量3~5 ml,术后(2.89±0.91)d排气,术后平均(8.0±2.11)d出院,无手术相关并发症及围手术期死亡。出院后均继续服用抗溃疡及抗菌药物。术后第3周随访并行胃镜检查,未见异常。结论:腹腔镜大网膜填塞修补法治疗胃、十二指肠溃疡穿孔效果肯定,安全可靠,具有良好的临床应用价值。     

腹腔镜下胃十二指肠穿孔修补术与开腹手术的对比

我们对 13例胃穿孔十二指肠穿孔患者行腹腔镜下修补术 ,并与 9例行传统开腹手术的患者比较 ,现介绍如下。资料与方法一、对象1.腹腔镜组 :对 2 0 0 0年 1月至 2 0 0 2年 6月间收治 13例胃十二指肠穿孔患者行腹腔镜下修补术 ,其中胃穿孔 5例 ,十二指肠穿孔 8例。本组患者年龄 2 8～ 4 7岁 ,平均 4 1 6岁 ,穿孔时间 4～ 10h ,平均 6 5h ,穿孔直径≤ 1 0cm ,术后病理学诊断均为上消化道溃疡穿孔。2 .开腹组 :对同期收治的 9例胃十二指肠穿孔患者行开腹手术 ,其中 4例为胃穿孔 ,5例为十二指肠穿孔。患者年龄32～ 4 8岁 ,平均 4 4 3岁 ,穿孔直…     

腹腔镜胃十二指肠溃疡穿孔修补术36例的体会

目的总结腹腔镜胃十二指肠溃疡穿孔修补术的手术经验。方法对2006年4月。2008年12月我科36例急性消化性溃疡穿孔患者采用腹腔镜修补进行回顾性分析。结果36例中十二指肠球部溃疡穿孔30例,胃窦部溃疡穿孔6例,穿孔直径0．5—1．1cm,手术时间30～185min,平均75min,手术均在腹腔镜下完成。1例术后发现穿孔闭合不良,经保守治疗治愈。其余35例术后恢复顺利,住院时间6－9d,术后无切口感染、腹腔脓肿、肠粘连等并发症。结论腹腔镜手术治疗消化性溃疡穿孔．只要具备成熟技术,与开腹手术同样安全有效。     

腹腔镜胃十二指肠溃疡修补术治疗急性胃十二指肠溃疡穿孔

目的:总结腹腔镜胃十二指肠溃疡修补术治疗急性胃、十二指肠溃疡穿孔的临床经验。方法:1997年6月至2007年12月35例急性胃十二指肠溃疡穿孔患者施行腹腔镜消化性溃疡穿孔修补术。结果:35例中十二指肠球部溃疡穿孔28例,胃窦部溃疡穿孔7例,穿孔直径0.5～0.8cm,手术时间80～180min,手术均获成功,术后患者疼痛轻微,均未使用止痛剂。术后康复顺利,术后住院5～10d,平均6.5d,切口均甲级愈合,痊愈出院。出院后予以内科根除幽门螺杆菌、口服H2受体拮抗剂治疗。结论:腹腔镜手术治疗急性胃、十二指肠溃疡穿孔,与开腹手术同样安全有效。胃溃疡穿孔患者术中需快速病理检查,若为恶性病变应中转开腹。     

腹腔镜消化性溃疡穿孔修补术23例

目的探讨腹腔镜消化性溃疡穿孔修补术的方法和治疗效果. 方法应用腹腔镜对23例消化性溃疡穿孔(十二指肠穿孔17例,胃窦部前壁穿孔5例,胃体部小弯侧穿孔1例)行穿孔修补﹑腹腔引流术. 结果手术均获成功,无手术并发症.3个月后胃镜复查,13例使用丝线者均有缝线外露,10例使用可吸收外科缝线者无缝线外露.随访6～27个月,平均18个月,3例十二指肠球部穿孔者仍有轻度嗳气,返酸,余无明显症状,无再穿孔. 结论腹腔镜消化性溃疡穿孔修补术安全可靠,术后继续正规内科治疗,效果满意.     

腹腔镜缝合修补消化性溃疡穿孔29例报告

目的:探讨腹腔镜缝合修补消化性溃疡的临床应用价值。方法:回顾分析2002~2007年我院应用腹腔镜缝合修补消化性溃疡穿孔29例患者的临床资料。结果:29例患者中胃窦部前壁穿孔9例,胃体部小弯侧穿孔7例,十二指肠球部前壁穿孔11例,2例病检诊断为癌性溃疡穿孔中转开腹。穿孔直径≤5mm 22例,>5mm 7例。27例手术成功,无术后并发症发生。手术时间和住院时间短,均痊愈出院,随访6~42个月,无复发。结论:腹腔镜缝合修补消化性溃疡治疗消化性溃疡穿孔安全可靠,是一种较理想的手术方法,术后继续正规内科治疗,效果满意。     

消化性溃疡穿孔非手术治疗病例报告及分析

目的探讨消化性溃疡穿孔的非手术治疗。方法回顾我院近年来消化性溃疡穿孔行非手术治疗的病例，并结合文献进行分析。结果十二指肠溃疡单纯穿孔患者非手术治疗均有效，而胃穿孔患者非手术治疗后中转手术。结论十二指肠溃疡单纯穿孔非手术治疗有可能成为一种趋势。     

Perforation in patients with bleeding ulcer

Twelve patients developed perforation after haemorrhage in a consecutive series of 840 cases admitted for bleeding chronic peptic ulcer. Death occurred in 3 of the 9 cases with duodenal ulcer and 1 of the 3 cases with gastric ulcer. There were 5 giant and 4 kissing duodenal ulcers and all 3 cases with gastric ulcer had a giant ulcer. The 12 patients were similar to the rest of the series in terms of ulcer site and shock on admission but were older and in poorer medical condition, more had ingested analgesics, more had giant ulcers and the mortality was greater (33% vs 6%). Giant ulceration was the only risk factor of potential clinical value as a predictor of the danger of ulcer perforation. One death occurred in 8 cases treated by early definitive surgery, suggesting this to be the treatment of choice for this unusual complication of peptic ulcer.     

Management of giant duodenal ulcer

Giant duodenal ulcer is a variant of peptic ulcer that is 2 cm in diameter or greater and essentially replaces the duodenal bulb. Diagnosis by upper gastrointestinal series is often missed, due to the large size of the ulcer, which causes it to look like a scarred duodenal bulb or duodenal diverticulum. This study reviews our experience with 32 patients who presented with giant duodenal ulcer between 1963 and 1982. Seventy-five percent of the patients were men between 30 and 81 years of age (mean age 59 years). Gastrointestinal hemorrhage was a presenting symptom in 75 percent of the patients and free perforation in 9 percent. Diagnosis was made by upper gastrointestinal series (24 patients), and endoscopy (11 patients), alone or in combination. Three patients were diagnosed at surgery and one at necropsy. Mean size of the ulcer was 3.5 cm in diameter, range 2 to 6 cm. Twenty-four patients were initially managed medically (mean length of treatment 41 months), with 2 deaths (hemorrhage) and 20 recurrences (83 percent). Twenty-seven operations were required in 25 patients. In 17 of the 25, medical treatment had failed. Seven of these patients required emergency surgery. Eight patients were managed primarily by surgery, of whom five presented emergently. There were three deaths in the surgical group after emergency surgery. In two of these patients, medical treatment had failed. There were no deaths among the elective surgery group. Twenty-five of the 27 operative procedures were definitive, acid-reducing operations (15 vagotomy and antrectomy and 10 vagotomy and drainage). Two patients underwent emergency exploration and oversewing of a giant perforated ulcer alone, and both patients required subsequent surgery because of symptoms. The results indicate that giant duodenal ulcer should be primarily surgically managed and that an acid-reducing procedure should be performed during primary surgery. These patients do very poorly with medical therapy, and the mortality rate is increased if emergency surgery is required for hemorrhage. Medical treatment alone is associated with a high morbidity (92 percent). Should operation be required, a definitive acid reduction operation is the procedure of choice.     

Laparoscopic and endoscopic management of perforated duodenal ulcers

BACKGROUND: Acid peptic perforation of the duodenum remains a surgical challenge. Plication alone may be satisfactory management if the ulcer diathesis is medically controlled. Laparoscopic management for plication has been safely applied in a variety of populations. This study assessed a combination of endoscopy and laparoscopy to manage early duodenal perforation. STUDY DESIGN: Forty-two patients with early (less than 12 hours) perforation were managed by laparoscopic plication and lavage. Endoscopy identified the site of perforation and guided repair in 35 of 42. All patients were followed with Helicobacter pylori treatment and examined by endoscopy at 3 months. Forty case control patients who had open procedures for duodenal perforation were evaluated for comparison. RESULTS: Endoscopic/laparoscopic management was completely effective and compared favorably with open procedures with regard to surgical time and complications. Endoscopic snaring of omentum and pulling into the defect proved to be an effective adjunct for plication. CONCLUSIONS: Endoscopic/laparoscopic repair of perforated duodenal ulcers is a safe and effective surgical tactic if followed by treatment for Helicobacter pylori.     

腹腔镜胃十二指肠溃疡穿孔修补术28例报告

目的:探讨腹腔镜手术在胃十二指肠溃疡穿孔修补术中的应用价值。方法:2003年1月~2006年8月我院为28例胃十二指肠溃疡穿孔患者行腹腔镜穿孔修补术。结果:27例成功完成腹腔镜手术,1例中转开腹。手术时间30~100m in,平均45m in,术后住院时间5~10d,平均7.8d,术后并发症少,无一例死亡。结论:腹腔镜胃十二指肠溃疡穿孔修补术具有痛苦小,恢复快,并发症少,住院时间短等优点,疗效确切,操作简单易行,值得在临床工作中推广应用。