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1.

Statement of problem

Conventional diagnostic aids based upon imagery and patient symptoms do not indicate whether restorative treatments have eliminated structural pathology.

Purpose

The purpose of this clinical study was to evaluate quantitative percussion diagnostics (QPD), a mechanics-based methodology that tests the structural integrity of teeth noninvasively. The study hypothesis was that QPD would provide knowledge of the structural instability of teeth after restorative work.

Material and methods

Eight participants with 60 sites needing restoration were enrolled in an IRB-approved clinical study. Each participant was examined comprehensively, including QPD testing. Each site was disassembled and microscopically video documented, and the results were recorded on a defect assessment sheet. A predictive model was developed for the pathology rating based on normalized fit error (NFE) values using data from the before treatment phase of the study published previously. Each restored site was then tested using QPD. The mean change in NFE values after restoration was evaluated by the pathology rating before treatment. The model was then used to predictively classify the rating after restoration based on the NFE values after treatment. The diagnostic potential of the rating was explored as a marker for risk of pathology after restoration.

Results

After restoration, 51 of the 60 sites fell below an NFE of 0.04, representing a greatly stabilized tooth site sample group. Several sites remained in the high-risk category and some increased in pathologic micromovement. Two models were used to determine severity with indicative cutoff points to group sites with similar values.

Conclusions

The data support the hypothesis that QPD can indicate a revised level of structural instability of teeth after restoration.  相似文献   

2.
The maxilla may be affected by squamous cell carcinoma (SCC) from both oral and sinus sites. We sought to determine whether the site of origin of the maxillary tumour, oral as compared to sinus, influences survival. Univariate Kaplan–Meier and multivariate Cox proportional hazard models analysis of 58 patients with SCC involving the maxilla, treated with curative intent, was conducted. The overall 5-year disease-free survival for the group was 41.7%. Five-year disease-free survival for oral subsite SCC was 56.8%, while for sinus subsite was only 21.6%. Univariate analysis found SCC of sinus origin to be associated with a poorer prognosis, however this was not confirmed on multivariate analysis. T-stage and positive margins were found to be the only independent risk factors. For SCC of the maxilla, sinus origin of the tumour per se does not confer a poorer prognosis; however, as a result of the complex anatomy of the midface, these tumours can present at an advanced stage, while surgical control of the disease can be more difficult, especially posteriorly. Tumour size and positive margins were the determinants of a poor prognosis in this group of patients with maxillary SCC.  相似文献   

3.

Objective

To provide insight of the setting reactions of Biodentine?, a hydraulic calcium silicate cement, based upon observations using Fourier Transform Infra-Red (FTIR) spectroscopy.

Methods

FTIR spectra of components before and during the setting reaction were taken using the attenuated total reflectance (ATR) technique. Measurements over wavelengths 600–4000 cm?1 were taken at regular intervals for two days.

Results

FTIR spectrum of Biodentine? powder revealed a number of peaks from 650 to 1100 cm?1 and a plateau from 1400 to 1500 cm?1, indicative of SiO and CO3-bonding, while the mixing fluid exhibited water peaks. Results following mixing displayed three distinct regimes; (i) incubation phase, during the first 35 min, when minimal change occurred, (ii) rapid transitory stage, between 35 and 90 min, when major changes occurred, and (iii) slow sustained reaction stage for remaining 45 h. Incubation appears to be associated with the presence of CO3-peaks. The transition region indicates formation of CaOH and Jennite OH-peaks, anticipated intermediate reaction phases. At 90 min, the end of second stage, CaOH and Jennite are replaced by a dominant Portlandite (Ca(OH)2)-peak and minor presence of Tobermorite, another anticipated intermediate phase, and water reduction. During the following 45 h Portlandite and Tobermorite decline while the water peak increases.

Significance

FTIR can be used to follow the chemical reactions in dental cements and provides insight into the relatively slow setting reactions of hydraulic calcium silicate cements.  相似文献   

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Background

Bisphosphonate-related osteonecrosis of the jaws (BRONJ) is a complication of the bisphosphonate (BP) treatment and its pathopysiology is still not fully understood. The existing preventive and treatment options require updates and more attention. Geranylgeraniol (GGOH) so far demonstrated an increased activity and viability of the cells previously treated with zoledronic acid (ZA). The aim of this study was to evaluate the in vivo effects of GGOH on the development of BRONJ.

Materials and methods

A total of 30 male Wistar rats were included in the study, divided into three groups: two experimental groups (EG1 and EG2) and a control group (CG). Rats from EG1 and EG2 were treated with 0,06 mg/kg ZA ip weekly in a duration of five weeks, while CG received saline ip. On the third week all animals underwent extraction of the lower right first molars. The rats from EG2 received a local solution of GGOH in concentration of 5 mM in the socket every day after the tooth extraction. The analyses included clinical evaluation on the wound healing and pathohistological evaluation for presence and level of osteonecrosis.

Results

EG2 showed significantly improved wound healing and tissue proliferation, when compared to EG1. EG2 significantly differed from EG1 and CG (p<0,05) for the presence of microscopical osteonecrosis (80% vs 22,2% vs 0%). Regarding to the number of empty lacunes without osteocytes and the level of necrosis, all groups demonstrated significant differences.

Conclusion

Geranylgeraniol in a form of local solution may be a promising option for prevention and treatment of BRONJ.  相似文献   

8.
Aesthetic outcome has gained in importance in the treatment of patients with orthognathic problems. Historically, Class III malocclusions have historically been treated by isolated mandibular setback and maxillary advancement, whereas bimaxillary procedures have recently become the more common option. Functional outcome and stability have been discussed previously. The aim of this observational study was to evaluate the effect of mandibular setback (BSSO) on the cervical region. We studied 38 Class III patients (20 women and 18 men, mean (SD) age 25 (0.8) years) who we identified from our clinical records and who were treated between 1 January 2002 and 30 December2012 with mandibular setback procedures and followed up for 6 months. To study the effect of the amount of mandibular setback on the aesthetic outcome we have distinguished between patients with less than 5 mm setback and those with 5 mm or more. In patients whose mandibular setback was less than 5 mm there was no significant change in cervical length. However, it decreased significantly in patients in whom the movement was 5 mm or more. Postoperatively the lip–chin–throat angle (p = 0.02), the length of the lower lip (p = 0.002), and the length of the upper lip (p = 0.003) from the aesthetic line also differed significantly between the 2 groups. Our observations strongly suggest that all these relations should be considered when treatment is being planned to avoid an unpleasant aesthetic impact on the chin region.  相似文献   

9.
Two new functionalized π-extended benzofuran catechol porphyrins and nanostructured Mn-porphyrins have been synthesized by a green one-pot method and structurally characterized by spectroscopic analysis. The electro-oxidation of 5,10,15,20-tetrakis(2,3-dihydroxyphenyl) porphyrins(1a-b) with four catechol units in the presence of 3-hydroxy-1H-phenalene-1-one (3) as bidentate nucleophile has been done and benzofuran rings have formed by the intermolecular and intramolecular Michel addition reactions. Coulometry and voltammetry results allowed us to propose four independent ECEC mechanisms for the electrochemical oxidation pathway. Functionalization of the porphyrins affected their photophysical properties such as the efficiency of the fluorescence that would support the energy transfer between the porphyrin core and the substituted subunits.  相似文献   

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Objectives

The main objective of the present in vitro study is to evaluate the antimicrobial activity and properties of irreversible hydrocolloid impression material incorporated with silver nanoparticles of varying size at different concentrations.

Methods

Silver nanoparticles of 80–100, 50–80, 30–50 and 10–20 nm size were added to irreversible hydrocolloid impression material at 0.5, 1.0, 2.0 and 5.0 wt%. Antimicrobial activity of the silver nanoparticle incorporated irreversible hydrocolloid was measured using disk diffusion method. The gel strength, flow, gelation time and permanent deformation were measured according to American Dental Association specification #18. Data were analyzed using analysis of variation at a confidence interval of 95% (α = 0.05).

Results

Silver nanoparticles of 80–100 nm size have imparted superior antimicrobial activity to the irreversible hydrocolloid in a dose-dependent manner whereas finer nanoparticle size did not exhibit any antimicrobial activity. The addition of silver nanoparticles did not alter the properties of irreversible hydrocolloid at 0.5 and 1.0 wt% whereas at higher concentrations significant differences in flow, gelation time and strength were observed.

Significance

The results of the present study indicate that silver nanoparticles of size range 80–100 nm are superior in imparting antimicrobial activity to irreversible hydrocolloid compared to finer particle size range.  相似文献   

12.
Juvenile cemento-ossifying fibroma (JCOF) is a rare lesion that exhibits a slow growing but may reach massive proportion and cause considerable cosmetic and functional problems. This lesion has the tendency for recurrence following incomplete excision. A case report of giant JCOF in a 46-year-old female with 23-year history is presented. Local excision and thorough curettage was performed and the normal skeletal structure was maximally preserved. 15-month follow up demonstrated no sign of recurrence.  相似文献   

13.
The main aim of the present investigation was to evaluate whether there is an association between completion of orthodontic treatment and quality of life measures, i.e. age, gender, socio-economic status, type of appliance and need for orthodontic treatment. The secondary aim was to evaluate whether compliance with orthodontic treatment (missed appointments and appliance breakages) was associated with age, gender, socio-economic status, or type of appliance. This was a multi-centre longitudinal observational study carried out on 144 patients (65 males and 79 females) aged 10-19 years. Baseline data were collected: patient age, gender, socio-economic status, Index of Orthodontic Treatment Need (IOTN), and type of appliance. Quality of life information, including orthodontic utility values and oral aesthetic subjective impact score (OASIS), were also collected at the start of treatment. The main outcome measure was whether a patient completed treatment. Compliance was assessed by recording the number of failed appointments and appliance breakages. Multiple regression analysis was used to investigate the association between independent and dependent variables. None of the baseline variables, including quality of life measures, were associated with a patient completing treatment, or their compliance with treatment (P > 0.05). Thus, quality of life measures (utility values or OASIS) do not add to our knowledge of who may complete, or co-operate with, orthodontic treatment. In addition, neither age, gender, socio-economic status nor clinical treatment need (IOTN) were useful in helping a clinician to choose potentially co-operative patients.  相似文献   

14.

Background

To demonstrate the value of videoroscopy in identifying lesions and alterations not seen by oroscopy and to select the area for biopsy.

Material and Methods

Eighty patients were subjected to anamnesis, physical exam, videoroscopy exam, toluidine blue test and biopsy. A diagram of the lips was created to record the exact location where the lesion was found.

Results

Physical exam identified 287 lesions, and videoroscopy identified 587 lesions; erythema and white lesions were the most common lesions associated with actinic cheilitis. Of the 59 performed biopsies, 32 (52.4%) cases were identified by videoroscopy that showed lesions that were not detected during physical examination.

Conclusions

The establishment of a diagram of the lip permitted registration of the precise location of the lesion. Videoroscopy was effective in locating lesions not seen by oroscopy. Both videoroscopy and the diagram of the lips allowed for better and earlier diagnosis and better patient follow-up for those with actinic cheilitis. Key words: Actinic cheilitis, potentially malignant disorder, videoroscopy, dermatoscopy, lip. oroscopy, diagram of lip.  相似文献   

15.
Expmisure of three dimensionil mmdibuiar reconstnietive plate was a main complcation is clinical application ,which includ intaond expusure and exlsuoul exposure .This paper reporbed two typical cases with plate expostre und reviewed the litralmes in unaly in the canses of plate exposure and its preventive measures .  相似文献   

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Objective To analyze the morphological characters and mechanism of Class Ⅱpatients. Methods 894 Class Ⅱ patients were collected from the orthodontic department, Peking University School of Stomatology from 1997 to 2000. The standardized coordinates of thecephalometric radiograms were obtained by Procrusts Superimposition (PS). Cluster analysis was carried out to divide the patients into different subdivisions and the cephalometric character of each template was analyzed. Resulst 894 patients were divided into 11 subdivisions with specialcharacteristics. The morphological templates were constructed by computer. Conclusions Procrusts method was effective to study the classification of the malocclusion. According to the template and its cephalometric value, Class Ⅱ malocclusion were mainly due to the mandiblar retrusion, and verticaldiscrepancy present in 60percent of the patients.  相似文献   

20.
The aims of this study was to define the effect of storage conditions of base plates, which consist of self-curing resin. Examinantions were made on the dimensional accuracy with the passage of time of base plate stored in water and air on a plaster model for standerdized maxillary edentulous. The following conclusions were obtained;
1.  The fit of base plate stored in water proved to be beter than that stored in air.
2.  No significant difference was noted among 7 times points.
3.  In terms of sites of measurement along the base plate, the more posteror the site of measurement, the greater the gap between a base plate and a cast, was observed.
4.  The best fitting base plate proved to be Ostron II. The second best fitting base plate proved to be Trayresin II.
  相似文献   

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