Antitumor activity of a lectibody targeting cancer-associated high-mannose glycans

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Neuropeptide Y attenuates cardiac remodeling and deterioration of function following myocardial infarction

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IL-1Ra gene transfer potentiates BMP2-mediated bone healing by redirecting osteogenesis toward endochondral ossification

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Allogeneic FLT3 CAR T Cells with an Off-Switch Exhibit Potent Activity against AML and Can Be Depleted to Expedite Bone Marrow Recovery

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Chimeric TIM-4 receptor-modified T cells targeting phosphatidylserine mediates both cytotoxic anti-tumor responses and phagocytic uptake of tumor-associated antigen for T cell cross-presentation

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Dual Targeting of Mesothelin and CD19 with Chimeric Antigen Receptor-Modified T Cells in Patients with Metastatic Pancreatic Cancer

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Antagonizing CD105 and androgen receptor to target stromal-epithelial interactions for clinical benefit

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Preferential delivery of lipid-ligand conjugated DNA/RNA heteroduplex oligonucleotide to ischemic brain in hyperacute stage

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Targeting Telomerase with an HLA Class II-Restricted TCR for Cancer Immunotherapy

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Catalase,a therapeutic target in the reversal of estrogen-mediated aging

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Gut microbial metabolite hyodeoxycholic acid targets the TLR4/MD2 complex to attenuate inflammation and protect against sepsis

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Locally secreted BiTEs complement CAR T cells by enhancing killing of antigen heterogeneous solid tumors

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Single-Cell Transcriptomic Analysis Reveals BCMA CAR-T Cell Dynamics in a Patient with Refractory Primary Plasma Cell Leukemia

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Stable HIV decoy receptor expression after in vivo HSC transduction in mice and NHPs: Safety and efficacy in protection from SHIV

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In Vivo Generation of CAR T Cells Selectively in Human CD4+ Lymphocytes

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GPR108 Is a Highly Conserved AAV Entry Factor

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Olaparib Suppresses MDSC Recruitment via SDF1α/CXCR4 Axis to Improve the Anti-tumor Efficacy of CAR-T Cells on Breast Cancer in Mice

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D2HGDH-mediated D2HG catabolism enhances the anti-tumor activities of CAR-T cells in an immunosuppressive microenvironment

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Long-term reversal of chronic pain behavior in rodents through elevation of spinal agmatine

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