神经根型颈椎病的康复护理

目的探讨康复护理在治疗神经根型颈椎病中的作用。方法对 244例随机分成2组,康复组采用电脑中频电疗仪加药治疗结合康复护理,对照组单纯采用电脑中频电疗仪治疗及常规护理。结果康复组总有效率为 97.3％,对照组为 84.6％,两组比较有显著性差异 (P< 0.05)。结论电脑中频电疗仪加药物并配合康复护理对疾病的功能恢复是十分重要的。     

神经根型颈椎病的康复护理

目的探讨康复护理在治疗神经根型颈椎病中的作用。方法对244例随机分成2组,康复组采用电脑中频电疗仪加药治疗结合康复护理,对照组单纯采用电脑中频电疗仪治疗及常规护理。结果康复组总有效率为97.3％,对照组为84.6％,两组比较有显著性差异(P<0.05).结论电脑中频电疗仪加药物并配合康复护理对疾病的功能恢复是十分重要的.     

电脑中频治疗泌尿系结石致疼痛症疗效观察

目的评价电脑中频治疗泌尿系结石致疼痛症疗效。方法采用北京产ＴＬ９００型电脑中频电疗仪，每日１～２次，每次２０分钟，５次为１疗程，电流量为最大耐受限，１疗程后判断疗效。结果疼痛缓解率１００％，其中治疗１～２次疼痛消失３２例，３～４次消失２８例，５次消失５例。结论电脑中频治疗仪治疗泌尿系结石致疼痛，疗效确切     

电脑中频电疗仪治疗软组织疼痛135例

电脑中频电疗仪疗法是近几年来在我国新开展的物理治疗方法之一。其特点是把临床经验处方全部程序化,集正弦调制、脉冲调制、音乐电等电流疗法于一体,使其高精度、多变化的丰富波形（正弦波、三角波、方波、尖波、锯齿波等）作用于人体。我科应用电脑中频电疗仪治疗软组织疼痛患者１３５例,并与超短波治疗组１３０例进行对照,观察疗效。报告如下。１资料和方法应用电脑中频电疗仪治疗软组织疼痛者为治疗组,患者１３５例,男６９例,女６６例;年龄９～７０岁;颈胸部２３例,腰骶部６９例,四肢部４３例;病程１～１２０ｄ。对照组用超…     

物理疗法治疗腰痛572例

腰痛为常见病症,重症者腰痛剧烈,腰肌紧张,活动受限.近4年来,我们应用电脑中频电流与超短波治疗腰痛共572例,经临床观察,电脑中频治疗组疗效显著,具有显效快,止痛效果较好等特点.资料与方法 电脑中频治疗组416例中,男249例,女167例;年龄18～78岁,病程最短者30min.最长者14年.应用北京翔运电子设备厂生产的K系列电脑中频电疗仪,根据治疗部位取适宜大小的带绒布衬垫的导电胶板电极,以温水浸湿后在腰骰部并置,沙袋加压固定,选用机内存贮的多步程序处方,输出电流强度为耐受限,20min,每日1次,疼痛并功能障碍较重者每日治疗2次,10次为1疗程.另将同期以超短波治疗腰痛156例作为对照组,其中男114     

中药熏蒸并超短波及电脑中频电疗治疗肩周炎的临床观察

目的为探讨肩周炎的物理治疗的临床效果。方法将90例肩周炎患者分成治疗组45例,对照组45例,治疗组采用中西医结合治疗即中药熏蒸并超短波及电脑中频电疗仪相结合治疗;对照组采用超短波与电脑中频电疗仪治疗,20次为1个疗程,疗程间隔7天,连续治疗2个疗程。结果治疗组愈显率93.33%,对照组愈显率42.23%,差异有显著性意义(P<0.01)。结论肩周炎的物理治疗中,中西医结合治疗是可行的,达到了提高康复治疗的目的。     

K8832-T电脑多功能电疗仪治疗软组织疾患的观察

我们于lop年6月一1997年6月用K8832．T电脑多功能电疗仪脉冲治疗腰部软组织疼痛疾患50例，获得较好效果，现报道如下。1资料和方法50例中男28，女22，年龄20－80岁，其中20－40岁20例，40-80岁30例，病程2天一3年，均经外科确诊后在我科治疗。我们采用北京翔云电子设备厂生产的K8832．T电脑多功能电疗仪，选用多步程序中频电流疗法中的】1号处方，即中频频率为ZIOIz，低频频率为l－15（）H调制波形为方波，指数波、三角波。治疗时将两个电极备装人衬垫内，并置于腰部痛区，用沙袋压住，电流量为耐受限，l次id，每次2（）fill，20次为一…     

电脑超声中频治疗痛症67例

１资料与方法 本组６７例，男性２２例，女性４５例，年龄２０～７４岁。病程最短几小时，最长１０余年。病种：神经性头痛、落枕、急性腰扭伤、踝关节扭伤、肋间神经痛。 采用沈阳新圳医用电子仪器公司生产的电脑超声中频治疗机，选用处方键Ｄ、Ｎ分别输出为电脑程控方波调制中频叠加超声波和中频不饱和尖峰波变频调制叠加超声波。各治疗 １５ ｍｉｎ，电量强度为耐受限，每日１次，５—１０次为１疗程。２结果 ６７例患者经治疗完全恢复５７例，显效４例，好转４例，无效２例，有效率９７％。３小结 电脑超声中频治疗机具有良好止痛作用。…     

电脑中频电疗仪治疗软组织疼痛135例

电脑中频电疗仪疗法是近几年来在我国新开展的物理治疗方法之一。其特点是把临床经验处方全部程序化．集正弦调制、脉冲调制、音乐电等电流疗法于一体．使其高精度、多变化的丰富波形(正弦波、三角波、方波、尖波、锯齿波等)作用于人体。我科应用电脑中频电疗仪治疗软组织疼痛患135例，并与超短波治疗组130例进行对照．观察疗效，报告如下。     

K8832-T电脑多功能电疗仪的应用

所谓多步程序中频电流疗法．就是针对不同的用途，将各种频率与波形优选组合，编制成若干种特定的多步程序中频电流处方，存储在电脑的存储器中．只要选择需要的处方号，启动后即可自动地按程序精出有特定治疗作用的中频电流系列。K8832-T电脑多功能电疗仪采用双极法，双向输出．一对电极无正负之分。每个处方均自动定时20min1次．治疗结束时自动切断输出电流。我院使用K8832-T电脑多功能电疗仪治疗落枕、网球肘、肩周炎等600余例．均取得较好疗效，现介绍如下．     

简易上肢屈肌痉挛抑制器结合电脑中频对脑卒中后肘关节康复的影响

目的：探讨简易上肢屈肌痉挛抑制器结合电脑中频治疗对脑卒中后肘关节康复的影响。方法将60例脑卒中偏瘫患者随机分成治疗组、抑制器组和中频组各20例,3组均常规进行康复训练,治疗组在进行电脑中频治疗时佩戴抑制器。对每例患者患侧肘关节在入组时和疗程2个月后分别进行 Fugl-Meyer上肢评分、改良Ashworth痉挛量表评定。结果3组治疗前后比较和组间比较差异均有统计学意义（P＜0．05）;三组的变化均数比较,治疗组2个月后Fugl-Meyer上肢评分、Ashworth痉挛量表评定恢复优于单纯抑制器组和单纯中频组（P＜0．05）。结论电脑中频结合抑制器治疗有助于改善偏瘫患者上肢肘关节痉挛。     

Abdominal malignancies in patients with Wilson's disease

BACKGROUND: Wilson's disease is associated with heavy copper overload, primarily in the liver. Copper is a toxic metal, and might be expected to be associated with cancer induction, as iron is in haemochromatosis. However, liver cancer is currently believed to be extremely rare in this disease, and other intra-abdominal malignancies have not been reported. AIM: To assess the frequency of abdominal malignant disease in patients with Wilson's disease on long-term follow-up. DESIGN: Retrospective study in two specialist Wilson's disease clinics: Cambridge/London and Uppsala. METHODS: We reviewed the case records of 363 patients seen at three centres: Addenbrooke's Hospital, Cambridge, 1955-1987; the Middlesex Hospital, London, 1987-2000; and the University Hospital, Uppsala, Sweden, 1966-2002. Patients were grouped by length of follow-up: 10-19 years; 20-29 years; 30-39 years; and 40 years or more. RESULTS: No cancers were seen in patients followed for <10 years. For patients in the 10-19 years group, the frequency was 4.2%; at 20-29 years, it was 5.3%; and at 30-39 years, 15%. No cancers were seen in the 40+ years follow-up group. The cancers consisted of hepatomas, cholangiocarcinomas, and poorly differentiated adenocarcinomas of undetermined primary site. DISCUSSION: Patients with Wilson's disease appear to be vulnerable to the formation of aggressive malignant intra-abdominal tumours during long-term follow-up, irrespective of treatment. Ultrasound scanning of the abdomen seems to be a useful screening procedure.     

血浆(1,3)-β-D葡聚糖检测对侵袭性肺部真菌感染的临床应用价值

目的 研究血浆(1,3)-β-D葡聚糖(BG)检测对侵袭性肺部真菌感染(IPFI)在疾病的诊断、治疗监测方面的应用价值.方法 收集拟诊为IPFI的患者55例,同时选取进行整形美容手术的无真菌感染的患者20例为阴性对照.应用沙保弱培养基和科玛嘉显色培养基对患者的痰液进行真菌分离培养,同时应用MB-80微生物动态快速检测系统动态检测患者血浆中BG水平.结果 55例拟诊的IPFI患者,经传统培养方法诊断23例阳性,阳性率为41.8%;经血浆BG检测35例为阳性,阳性率为63.4%,20例阴性对照组均为阴性.10例确诊IPFI患者治疗后连续检测血浆BG,8例经临床抗真菌治疗后血浆BG水平逐渐降低趋于阴性,治愈.结论 血浆BG检测较传统的真菌培养分离鉴定方法简便、快速、阳性率高,是诊断IPFI的早期、有效、快速的方法.     

The effects of early application of simvastatin on C-reactive protein level, blood lipids, and the clinical course of acute coronary syndrome

In spite of a large number of studies on the use of HMG-CoA-reductase inhibitors (statins) in treatment of different forms of coronary artery disease, the efficacy of their early administration in acute coronary syndrome (ACS) is still unclear. The purpose of the present investigation was to study the effects of medium doses (40 mg per day) of simvastatin on the clinical course of ACS and blood levels of C-reactive protein (CRP) and lipids in ACS patients to whom the drug was administered on the first day of the disease. One hundred and eight patients with ACS were randomized into two groups: the control group receiving standard therapy, and the main group receiving in addition 40 mg of simvastatin beginning on the first day of the disease. Blood levels of lipids and CRP were measured by a precise qualitative technique on the first and fourteenth days of the disease. The clinical course of the disease was evaluated during six months from the first day of hospital stay. Mean CRP level decreased significantly within two weeks in the group of patients receiving simvastatin (from 14.9 +/- 9.7 to 7.6 +/- 6.0 mg/l; p = 0.02). In the control group CRP concentration decreased less and not significantly (from 16.1 +/- 7.3 to 13.2 +/- 6.8 mg/l; p = 0.18). Two main types of the dynamics of CRP level were revealed in the ACS patients. Most patients in both groups displayed a decrease in CRP level by the fourteenth day of the disease. At the same time, in some patients CRP level grew during this period, and these patients had stenocardia and required repeated hospital admissions due to ACS recurrence significantly more frequently during the following six months (relative risk 1.4; 95% confidence interval 1.1 to 1.8). The frequency of postinfarction stenocardia was the most substantial and significant clinical difference between the groups (50.9% in the control group, and 23.6% in the main group, p = 0.04). Thus, early therapy with simvastatin in ACS lowers SRP level and the frequency of postinfarction stenocardia. The elevation of CRP level during the first two weeks of the disease is a poor prognostic sign.     

人白细胞抗原B位点基因芯片分型技术研究

目的 探讨基因芯片技术在进行北方汉族人群人白细胞抗原B位点（HLA-B）分辨度分型的价值.方法 根据中国北方汉族人群HLA-B常见基因位点及临床分型分辨度特征,设计特异性寡核苷酸中分辨度分型探针,制成HLA-B基因分型芯片.采用荧光标记引物和不对称聚合酶链反应（PCR）扩增HLA-B 2、3外显子,产物与芯片探针杂交后经荧光扫描,并用特定软件分析判断阳性探针,以确定样品基因型.结果 用中分辨度探针从30份北方汉族人标本中可分出HLA-B 7～83范围的42个B抗原等位基因,与顺序特异引物聚合酶链反应（PCR-SSP）分型方法对比,多检出3个HLA-B14、73和82新等位基因.结论 HLA-B基因芯片具有较高的精确度和特异性,可一张芯片多人份检测,适合用于临床HLA-B抗原分型.     

计算机辅助彩色M型超声心动图无创估测肺血管阻力的研究

目的 评价自行设计的计算机软件辅助彩色M型超声心动图无创估测肺血管阻力(PVR)的可行性及准确性.方法 20例先天性心脏病患者和20例正常儿童为研究对象,应用彩色M型超声心动图检测肺动脉血流传播速度(VPE)并进行比较;应用自行设计的计算机软件测量先心病患者的肺动脉血流传播速度(VPC),并与右心导管技术所测的PVR对比.结果 先天性心脏病患者彩色M型超声测得的VPE明显低于正常儿童[(38.38±18.89)cm/s对(80.34±15.65)cm/s,P＜0.01],且与心导管所测的PVR值显著相关(r=-0.69,P＜0.01).计算机软件测得VPC与PVR高度相关(r=-0.78,P＜001),且重复性较好.VPC＜35.910预测PVR＞16 kPa·S·L-1的灵敏性为92.9%,特异性为100%.结论 应用计算机辅助彩色M型超声心动图技术测量肺动脉血流传播速度可以比较准确地无创估测肺血管阻力.     

对冠心病患者电子健康素养操作情况的研究

目的研究冠心病患者实际电子健康素养水平,探讨其在使用互联网进行疾病相关健康任务搜索时所遇到的问题,旨在为构建冠心病患者电子健康素养的干预方案提供参考。方法采用目的抽样法,选取2018年6—12月在杭州市某三级甲等医院住院的20例冠心病患者进行操作试验,受试者在计算机上操作由研究者设计的关于冠心病网络健康的6项试验任务。试验中,受试者被要求应用有声思维法,与此同时屏幕录像专家记录其进行任务操作时所产生的屏幕活动轨迹、图像和声音,以此来共同记录受试者的试验资料。此外,由2名研究者记录受试者操作6项任务的完成度、表现情况和时间,最后采用Colaizzi七步分析法对试验资料进行归纳分析。结果冠心病患者在使用互联网进行疾病相关健康任务搜索时所遇到的问题可归纳为操作计算机和浏览器、在Web上导航和定位、利用搜索策略、评估信息的相关性和可靠性4个主题。结论相关健康专业人员进行冠心病患者电子健康培训时,应关注患者的计算机基本操作技能、健康信息搜索策略及网络健康信息质量评估能力,从而提高其电子健康素养。     

An investigation into the validity of the present classification of inflammatory bowel disease

To assess the validity of the present subdivision of patients with inflammatory bowel disease into those with Crohn's disease of the small bowel or of the colon and those with ulcerative colitis, 252 patients with inflammatory bowel disease have been studied by questionnaire and case note review. One hundred and seventy-two variables concerning the nature and frequency of symptoms in remission and relapse, the incidence of complications and results of investigation have been analysed by computer. As expected, there were many highly significant variables between patients with ulcerative colitis and those with Crohn's disease of the small bowel. The latter showed evidence of a more severe disease course with more complications. There were similar, although less marked, differences between patients with Crohn's disease of the colon and those with Crohn's disease of the small bowel. There were very few differences in disease course between patients with Crohn's disease of the colon and those with ulcerative colitis. The results suggest that while separate classification of patients with Crohn's disease of the small bowel is justified on clinical grounds, the present separation of patients with disease confined to the colon into groups labelled ulcerative colitis or Crohn's disease of the colon is not. Alternative methods of classification should therefore be investigated.     

小汤山医院680例SARS患者药物利用分析

目的调查分析小汤山医院680例临床确诊SARS患者治疗期间的药物利用情况. 方法采用HIS系统回顾性分析小汤山医院临床确诊的680例SARS患者的病案及用药记录,分别运用计算机病例分型模型(A、B、C、D型)和临床分型模型(普通型、重症型)分组,统一采用合理用药指标:限定成人日剂量(defined daily dose, DDD)、药物利用指数(drug utilization index, DUI)、用药例次数、医嘱数及人均药费、日均药费等,评价各组间的差异. 结果 680例SARS患者共计应用17大类359种药物,应用病例数最多的是抗菌药物.应用经费最多的是糖皮质激素和大输液类药物.DDDs排序最高的为免疫调节剂和维生素药物.应用总天数最多的是大输液和维生素类药物.药费最高的是甲基强的松龙注射剂.C型、D型和重症型SARS患者的年龄、死亡率、用药品种、用药频次及经费均显著高于A型和普通型SARS患者. 结论按WHO推荐的合理用药指标DUI＝1标准,359种药物中DUI小于、等于和大于1的比例分别为37%、30%和33%.抗病毒药用量不足,激素类用量过大.计算机病例分型客观真实、速度快、易标化,具有推广潜质.