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1.
目的:观察醒脑静注射液治疗重度颅脑损伤临床疗效。方法:将46例患者分成2组。治疗组33例,对照组13例,2组有可比性。2组均予常规西医治疗,包括手术、脱水降颅压、营养脑细胞、脑保护等,治疗组在此基础上予醒脑静注射液10~30ml加入5%葡萄糖注射液100~250ml中静滴;每日1次。2组均治疗14d为1个疗程并观察疗效。结果:2组临床疗效无显著性差异,2组格拉斯哥昏迷评分比较有显著性差异(P0.05)。结论:醒脑静注射液能够改善重度颅脑损伤患者意识障碍。  相似文献   

2.
目的:观察醒脑静注射液治疗重症中暑的疗效。方法:对照组8倒予以吸氧、物理降温、静滴冰盐水及症支持治疗,治疗组在上述基础上用醒脑静30ml加入250ml生理盐水中静滴。结果:醒脑静治疗组体温、血压、意识状态和肌肉紧张度恢复时间较对照组明显缩短。结论:醒脑静注射治疗重症中暑有很好的退热、催醒作用,且无副作用、值得推广应用。  相似文献   

3.
目的:观察莫尼地平与灯盏细辛联合应用对急性脑梗死病人神经功能恢复的临床疗效。方法:将90例急性脑梗死病人随机分为观察组45例,对照组45例。观察组在常规治疗的基础上用0.9%NS 250ml加灯盏细辛注射液40ml静滴,1次/日,同时口服尼莫地平片20mg/次,3次/日。14天1个疗程;对照组在常规治疗的基础上静滴灯盏细辛注射液,剂量、方法、疗程同观察组。疗程结束后两组病例进行疗效比较。结果:观察组总有效率95.5%,对照组总有效率82.2%。结论:莫尼地平与灯盏细辛联合应用治疗急性脑梗死可提高治愈率,减少致残率。  相似文献   

4.
摘要目的:观察用葛根素治疗2型糖尿病并发急性脑梗死的疗效。方法:将118例2型糖尿病并发急性脑梗死病人随机分为治疗组和对照组。入组所有病人入院后根据病情给予口服降糖药或胰岛素、脱水剂、脑细胞活化剂、调整血压、抗感染等对症治疗。治疗组予葛根素400mg加入生理盐水250ml静滴1次/d,14天为一个疗程。对照组予血栓通10ml加入生理盐水250ml静滴1次/d,14天为一个疗程。结果:治疗组总有效率为88.9%,对照组总有效率为65%,两组疗效比较有显著差异(P<0.05)。结论:葛根素治疗2型糖尿病并发急性脑梗死有较好的疗效。  相似文献   

5.
银杏达莫注射液治疗急性脑梗死的临床观察   总被引:1,自引:0,他引:1  
姚军  卢小容 《临床医学》2010,30(2):44-45
目的观察银杏达莫注射液治疗急性脑梗死的临床疗效和安全性。方法将64例急性脑梗死患者随机分为对照组和观察组各32例,对照组给予灯盏花素注射液50mg加生理盐水250ml静脉滴注,每日1次,连用14d。观察组给予银杏达莫注射液20ml加生理盐水250ml静脉滴注,每日1次,连用14d。14d后判定两组的临床疗效和进行神经功能缺损评分。结果观察组临床的总有效率为90.6%,优于对照组的68.8%,差异有统计学意义(P0.05);两组治疗后神经功能缺损评分均较治疗前明显下降,且观察组优于对照组(P0.05)。结论银杏达莫注射液治疗急性脑梗死是安全有效的,值得临床推广应用。  相似文献   

6.
目的 观察丹红注射液治疗急性脑梗死的临床疗效.方法 120例急性脑梗死患者随机分为两组,对照组60例给予血塞通0.4g加入0.9%氯化钠250ml静滴,治疗组60例给予丹红注射液30 ml加入0.9%氯化钠250ml静滴,两组疗程均为14 d.比较治疗前后两组患者神经功能评分的变化及临床疗效.结果 治疗组显效率、有效率明显优于对照组,P<0.01.2组神经功能缺损评分与治疗前比较,均明显下降,P<0.01;组间治疗后比较,差异有统计学意义(P<0.01).结论 丹红注射液可明显改善急性脑梗死患者的神经功能缺损.  相似文献   

7.
杨建明 《华西医学》2009,(8):1925-1927
目的:探讨急性脑梗死的常规治疗和加用依达拉奉治疗的疗效变化。方法:100例急性脑梗死患者随机分为治疗组和对照组,每组各50例,对照组用常规治疗方法(灯盏花和胞二磷胆碱静滴,口服阿司匹林等治疗),治疗组在常规治疗基础上加用生理盐水250 mL+依达拉奉注射液30 mg静脉滴注,每日2次,7-14天为1个疗程,进行疗效评定。治疗前、治疗后14天和21天对患者进行欧洲卒中评分(ESS)、日常生活活动能力(ADL)评定。通过增分率判断疗效,同时记录不良反应。结果:治疗组14天和21天评定ESS的有效率分别为78.0%和84.0%,对照组为52.0%和58.0%;14天和21天评定ADL的有效率治疗组为80.0%和88.0%,对照组为56.0%和66.0%;治疗组无明显不良反应.结论:依达拉奉治疗急性脑梗死安全有效。  相似文献   

8.
闫军  韩亚州 《临床医学》2011,31(1):35-36
目的观察法舒地尔注射液对急性脑梗死患者的治疗作用及临床疗效。方法选择2008年1月至2009年7月于我院神经内科住院的120例急性脑梗死患者,随机分为治疗组和对照组,治疗组60例用法舒地尔注射液30 mg加生理盐水100 ml静脉滴注,每日2次。对照组60例应用丁咯地尔针200 mg加生理盐水250 ml静脉滴注,每日1次,连续应用14 d。结果两组患者神经功能缺损评分明显下降,日常生活能力有较大的提高,但治疗组优于对照组。结论法舒地尔注射液对急性脑梗死有较好的治疗作用。  相似文献   

9.
目的:观察醒脑静注射液对有机磷农药中毒患者意识障碍的治疗效果。方法:将40例有机磷农药中毒伴意识障碍患者随机分为治疗组和对照组。治疗组20例在常规治疗基础上加用醒脑静注射液治疗,对照组20例采用常规综合治疗。结果:治疗组患者意识清醒时间为(5.64±3.96)小时,与对照组(8.35±3.72)小时比较有显著性差异(P<0.05)。结论:醒脑静注射液对有机磷农药中毒伴意识障碍患者有促醒作用。  相似文献   

10.
目的:观察依达拉奉联合丹参酮IIA磺酸钠治疗急性脑梗死的疗效.方法:选择发病7天以内的96例脑梗死患者随机分为治疗组45例,对照组51例.治疗组给予依达拉奉30mg加生理盐水100ml,每日2次;联合丹参酮IIA磺酸60mg加生理盐水250ml,每日1次,连续14天.对照组予丹参酮IIA磺酸60mg加生理盐水250ml,每日1次,连续14天.结果:治疗组有效率、显效率分别为91.1%、66.7%,明显高于对照组的82.4%、27.5%,2组比较差异有显著统计学意义(P均<0.01).结论:依达拉奉联合丹参酮IIA磺酸钠治疗急性脑梗死,疗效确切,能够更好得保护缺血区脑细胞功能,促进神经功能缺损的恢复.  相似文献   

11.
Objective: To identify patterns of nonfatal and fatal penetrating trauma among children and adults in New Mexico using ED and medical examiner data.
Methods: The authors retrospectively sampled in 5-year intervals all victims of penetrating trauma who presented to either the state Level-1 trauma center or the state medical examiner from a 16-year period (1978–1993). Rates of nonfatal and fatal firearm and stabbing injury were compared for children and adults.
Results: Rates of nonfatal injury were similar (firearm, 34.3 per 100,000 person-years; stabbing, 35.1). However, rates of fatal injury were significantly different (firearm, 21.9; stabbing, 2.7; relative risk: 8.2; 95% confidence interval: 5.4, 12.5). From 1978 to 1993, nonfatal injury rates increased for children (p = 0.0043) and adults (p < 0.0001), while fatal penetrating injury remained constant. The increase in nonfatal injury in children resulted from increased firearm injury rates. In adults, both stabbing and firearm nonfatal injury rates increased.
Conclusions: Nonfatal injury data suggest that nonfatal violence has increased; fatal injury data suggest that violent death rates have remained constant. Injury patterns vary by age, mechanism of trauma, and data source. These results suggest that ED and medical examiner data differ and that both are needed to guide injury prevention programs.  相似文献   

12.
Three supplementary perspectives are presented arguing that interprofessional collaboration is both necessary and desirable. Nonetheless, there are often too many serious intra-professional barriers and obstacles to interprofessional collaboration to make it successful. Some of these barriers, it is argued and illustrated, are found in the multiple ways in which professional identity is tacitly acquired and embodied in the practitioners' habitual, everyday practice. The paper then explores ways in which reflection, especially Second order reflection, can help to elucidate and overcome these obstacles, as well as increasing professional adaptability and competence.  相似文献   

13.
This is a new method for the determination of creatine kinase isoenzyme MB activity in serum. The method uses direct activity measurement of creatine kinase B subunit activity after blocking of CK-M subunit activity by inhibiting antibodies. The test takes no longer than 15 min. The method yields an intra-serial C.V. of 2.0-12.9%, and a C.V. from day to day of 5.5%. The detection limit is 3.4 U/l creatine kinase MB. In the 95 cases with proven myocardial infarction several types of creatine kinase MB activity kinetics could be determined. The percentage of creatine kinase MB of peak CK-total is 6-25%, with a mean of 11.1%. The amount of creatine kinase MB with respect to total CK activity after reinfarction is higher than the amount after initial infarction.  相似文献   

14.
目的 探讨手转胎头术失败的原因与分娩结局.方法 选择2008年1月至2010年12月于我院住院分娩的持续性枕横位、枕后位产妇198例,根据行手转胎头术后结果分为成功组126例、失败组72例.比较两组分娩结局,对比分析失败原因.结果 失败组胎儿体质量≥3500 g的发生率[76.4%(55/72)]明显高于成功组[31.7%(40/126)],差异有统计学意义(x2=30.177,P=0.001)、失败组宫缩乏力发生率[58.3%(42/72)]高于成功组[38.1% (48/126)],差异有统计学意义(x2=7.569,P=0.006)、失败组骨盆临界或轻度狭窄发生率[38.9% (28/72)]高于成功组[23.8%(30/126)],差异有统计学意义(x2 =5.030,P=0.002)、失败组手转胎头时机不当(宫口开大<6 cm、胎头位于坐骨棘上及宫口开大8~10 cm、胎头位于坐骨棘下≥2 cm)发生率[61.1%(44/72)]高于成功组[38.9%(49/126)],差异有统计学意义(x2=9.084,P=0.003).失败组母儿并发症(产后出血、产褥病率、胎儿窘迫、新生儿窒息)发生率高于成功组(x2 =9.586,P=0.002、x2=9.334,P=0.002、x2=5.910,P=0.015、x2=5.240,P=0.022)、失败组剖宫产发生率[72.2%(52/72)]明显高于成功组[34.1 %(43/126),x2=26.641,P=0.001)].结论 手转胎头术能使难产变顺产,降低剖宫产率,减少母儿并发症,但须积极预防、处理导致手转胎头术失败的原因,对矫正失败后继续矫正及试产应慎重.  相似文献   

15.
ABSTRACT

The Cochrane Library of Systematic Reviews is published quarterly as a DVD and monthly online. The January 2011 issue (first quarterly DVD for 2011) contains 4515 complete reviews, 1985 protocols for reviews in production, and 13,521 one-page summaries of systematic reviews published in the general medical literature. In addition, there are citations of 641,000 randomized controlled trials, and 14,018 cited papers in the Cochrane methodology register. The health technology assessment database contains over 9300 citations. One hundred and seven new reviews have been published in the last 3 months, of which five have potential relevance for practitioners in pain and palliative medicine.  相似文献   

16.
Ranganath C  Heller AS  Wilding EL 《NeuroImage》2007,35(4):1663-1673
Although substantial evidence suggests that the prefrontal cortex (PFC) implements processes that are critical for accurate episodic memory judgments, the specific roles of different PFC subregions remain unclear. Here, we used event-related functional magnetic resonance imaging to distinguish between prefrontal activity related to operations that (1) influence processing of retrieval cues based on current task demands, or (2) are involved in monitoring the outputs of retrieval. Fourteen participants studied auditory words spoken by a male or female speaker and completed memory tests in which the stimuli were unstudied foil words and studied words spoken by either the same speaker at study, or the alternate speaker. On "general" test trials, participants were to determine whether each word was studied, regardless of the voice of the speaker, whereas on "specific" test trials, participants were to additionally distinguish between studied words that were spoken in the same voice or a different voice at study. Thus, on specific test trials, participants were explicitly required to attend to voice information in order to evaluate each test item. Anterior (right BA 10), dorsolateral prefrontal (right BA 46), and inferior frontal (bilateral BA 47/12) regions were more active during specific than during general trials. Activation in anterior and dorsolateral PFC was enhanced during specific test trials even in response to unstudied items, suggesting that activation in these regions was related to the differential processing of retrieval cues in the two tasks. In contrast, differences between specific and general test trials in inferior frontal regions (bilateral BA 47/12) were seen only for studied items, suggesting a role for these regions in post-retrieval monitoring processes. Results from this study are consistent with the idea that different PFC subregions implement distinct, but complementary processes that collectively support accurate episodic memory judgments.  相似文献   

17.
The Department of Veterans Affairs (VA) in the USA operates a network of 172 medical centres which all utilize a hospital information system (HIS) which has been developed and is currently maintained by the VA. During the past several years, an image management and communication module has been developed, installed and clinically utilized at the Washington DC and Maryland VA Medical Centres. This image management and communication system, referred to as the decentralized hospital computer program (DHCP) imaging system, is fully integrated with a commercial picture archiving and communication system (PACS). The system is utilized to capture, archive, and display all images generated within the hospital including radiology, nuclear medicine, pathology, endoscopy, bronchoscopy, and dermatology, intraoperative photographs, ECG data, and a limited number of paper documents. The ultimate goal of the project is to have all patient text and image data available at any clinical workstation to any authorized user anywhere within the network of medical centres. Clinical requirements for an imaging workstation include ease of use, rapid and reliable access to the complete set of patient information, and images which are of acceptable quality to meet the requirements of the user and the subspecialty. Patient confidentiality and data security must be safeguarded at all times. Integration of the images with the remainder of the patient's database was found to be critical to the success of the project. The experience at the Washington and Maryland facilities suggests that an imaging system that is successfully integrated with a hospital information system can provide substantial clinical and economic benefits both within and among medical centres. Clinical acceptance and utilization of the system has been excellent, particularly in diagnostic radiology where DHCP Imaging has been interfaced to a commercial PAC system. Based upon this initial experience, the VA has begun to deploy the system throughout its large network of medical centres.  相似文献   

18.
19.
目的 探讨俯卧位通气对高海拔地区肺复张术(RM)治疗无效急性呼吸窘迫综合征(ARDS)患者的治疗作用.方法 从海拔2260m的地区医院筛选RM治疗无效的41例ARDS患者[平均氧合指数( PaO2/FiO2)较RM前升高<20%视为RM无效],依不同病因分为肺内源性ARDS组(ARDSp组)和肺外源性ARDS组(ARDSexp组),每组再按信封法随机分为俯卧位组和仰卧位组,即ARDSp俯卧位组(11例)、ARDSp仰卧位组(9例)、ARDSexp俯卧位组(10例)、ARDSexp仰卧位组(11例).在通气前及通气1、2、3、4h监测动脉血氧分压( PaO2)、PaO2/FiO2、静态顺应性(Cst)、气道阻力(Raw)的变化.结果 通气lh时,ARDSexp俯卧位组PaO2/FiO2( mm Hg,l mm Hg=0.133 kPa)即较通气前显著升高(157.4±40.6比129.3±48.7,P<0.05),并随通气时间延长呈持续增高趋势,4h达峰值(219.1 ±41.1);且ARDSexp俯卧位组通气3h内PaO2/FiO2较其他3组显著增高,另3组间则差异无统计学意义.ARDSp俯卧位组、ARDSexp俯卧位组通气4h时PaO2/FiO2均较相应仰卧位组显著增高(208.8±39.7比127.4±47.1,219.1±41.1比124.9±50.8,均P<0.05).4组通气前后Cst无显著改变,各组间差异也无统计学意义.ARDSp俯卧位组通气4h时Raw(cmH2O·L-1·s-1)较通气前显著降低(6.8±1.7比10.7±1.8,P<0.05),且明显低于其他3组;其他3组各时间点Raw组内及组间比较差异均无统计学意义.结论 俯卧位通气作为ARDS机械通气重要策略之一,可以改善RM无效高原ARDS患者的氧合,为抢救患者赢得宝贵的时间.  相似文献   

20.
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