抚触对新生儿生理性黄疸影响的研究

目的 :观察抚触对新生儿生理性黄疸的影响。方法 :随机将 10 0例足月新生儿分为抚触组和对照组。抚触组由专人对生后 1周内的新生儿进行抚触 ,对照组按婴儿常规护理。观察两组新生儿的排便次数、出生 2 4h内排便量、经皮胆红素 (TCB)变化动态。结果 :抚触组新生儿排便次数多于对照组 (P<0 0 5 ) ,出生 2 4h内排便量明显增加 (P <0 0 1) ,经皮胆红素明显低于对照组 (P <0 0 5 )。结论 :抚触可减轻新生儿生理性黄疸程度     

新生儿游泳＋抚触疗法对新生儿胆红素的影响

目的：探讨新生儿游泳＋抚触疗法对新生儿胆红素的影响。方法：对200例生理产出生的足月正常新生儿随机分为两组，对照组100例给予单纯沐浴护理，研究组100例给予游泳＋抚触疗法。观察两组新生儿胆红素的动态变化及24h后母乳喂养次数、新生儿体重、睡眠时问。结果：研究组新生儿胆红素指数明显低于对照组，研究组有2例出现高胆红素血症，对照组13例出现高胆红素血症；研究组新生儿母乳喂养次数、新生儿体重、睡眠时问明显优于对照组。结论：新生儿游泳＋抚触疗法可减少“肠一肝”循环，降低高胆红素血症的发生率，促进新生儿生长发育。     

穴位按摩和哺乳频率对母乳喂养性黄疸胆红素水平的影响

目的:探讨穴位按摩和增加哺乳频率对母乳喂养性黄疸 (BFJ)胆红素水平的影响。方法:随机将 18例母乳喂养性黄疸患儿分为两组,常规治疗护理相同。干预组 60例,采取泻黄汤穴位按摩和在按需哺乳的基础上适当增加哺乳频率;对照组 58例常规治疗护理,按需哺乳。结果:干预组与对照组哺乳次数分为 8 .9±1 .6次 /d与5. 7±1. 3次 /d;排便次数分别为 5. 5±1 .0次 /d与 3 .0±1.2次 /d;黄疸消失所需光疗时间分别为 31±8h与 40±9h;胆红素每天下降值为 31 .4±10 .2与 23. 2±8 .4,上述结果差异均有显著性 (P<0 .01)。结论:对BFJ患儿采取泻黄汤穴位按摩和在按需哺乳的基础上适当增加哺乳频率,可促进胆红素排泄,降低血清胆红素水平。     

The effect of foot reflexology massage on delirium and sleep quality following cardiac surgery: A randomized clinical trial

BackgroundDelirium is the most common neurologic disorder after cardiac surgery and affects both short and long-term outcomes. This study was conducted to evaluate the effect of foot reflexology massage on the incidence of delirium and sleep quality in patients undergoing cardiac surgery.MethodsIn this randomized clinical trial, 60 patients who were candidates for CABG surgery were randomly assigned into two equal groups (n = 30); intervention and control groups. In the intervention group, foot reflexology massage was done on each foot for 15 min, for two consecutive days. Delirium observation screening scale, the Richard Campbell sleep questionnaire (RSCQ), and pain intensity using VAS were compared.Resultsin the second postoperative day, delirium was observed in 8 (26.7 %) and 7 (23.3 %) of patients in the intervention and control groups, respectively (p > 0.05). The measured odds ratio for the effect of massage on delirium is 0.83 (95 %CI 0.71–2.69, p = 0.76). The difference in RSCQ scores was not significant between groups of intervention and control (68.32 ± 10.41 VS. 62.80 ± 11.86, P = 0.06). The pain intensity was lower in the intervention group (P < 0.001).ConclusionFoot reflexology was not effective in reducing delirium and improving the sleep quality, but the pain intensity was decreased. It seems that the precise pathology and predicting model of delirium should be identified, and appropriate interventions should be planned accordingly.     

The effect of vitamin C supplementation in the last month of pregnancy on neonatal bilirubin levels; A double-blind randomized clinical trial

ObjectivesJaundice is a typical condition in the neonatal period, particularly in the Asian continent. Drowsiness and disruption of breastfeeding, behavioral and neurological disorders, hearing loss and mental retardation are the results of impairment in controlling it. The increase in oxidant substances can stimulate the heme oxygenase enzyme and increase the conversion of heme to bilirubin. In some studies, vitamin C levels in the blood of infants with hyperbilirubinemia were lower than in healthy infants.DesignIn this double-blind clinical trial study, 144 healthy pregnant women aged 20–40 years who were in 34th weeks of gestation were randomly divided into intervention, and control groups and until the end of pregnancy, they took a 500 mg tablet of vitamin C or placebo (Preparation of starch) daily. Demographic information, dietary intake, and physical activity level of the participants were also evaluated. The total blood bilirubin level was measured on the fifth day after birth using a sample of the neonatal heel. Statistical analysis was performed using SPSS software version 22. In this study P-value < 0. 05 was considered significant.ResultsOf the 144 participants, 128 of them completed the intervention. There was no significant difference between the two groups at the level of vitamin C intake through diet, and anthropometric indices, but the total bilirubin level in the neonates of the two groups was statistically different (P = 0.02).ConclusionVitamin C supplementation in the last month of pregnancy had a significant effect on neonatal bilirubin level and decreased it significantly.     

开放式沐浴与抚触在新生儿中的应用效果

目的：探讨开放式沐浴与抚触在新生儿中的应用效果。方法：2013年1~4月我院产科爱婴区住院的新生儿400例,按入院顺序分为观察组和对照组各200例。观察组采取开放式沐浴与抚触模式,每次新生儿沐浴允许一名家长参与;对照组采取封闭式沐浴与抚触模式,新生儿沐浴时家长不参与。对两组产妇进行调查,了解其对护士的服务态度、安全意识、其础护理、工作能力、告知注意事项及关爱新生儿等项目的满意程度。结果：观察组产妇对护士的服务态度、安全意识、基础护理、工作能力、告知注意事项及关爱新生儿方面的满意程度高于对照组（P〈0.05）。结论：开放式新生儿沐浴与抚触的满意度明显提高,值得临床推广应用。     

The effect of foot reflexology before suctioning on pain and SPO2 in neonates under nasal CPAP hospitalized in the NICU

IntroductionSuctioning procedures in neonates under nasal CPAP and the use of reflexology as a non-invasive method are inevitable. Accordingly, this study aims to determine the effect of foot reflexology before suctioning on pain and SPO2 in neonates under nasal CPAP, who were admitted to the neonatal intensive care unit (NICU).MethodsThis quasi-experimental crossover study was conducted among 40 neonates under nasal CPAP, who were admitted to the NICU of Ali Ibn Abitaleb Hospital in Rafsanjan, Southeastern Iran. The neonates were divided into one of two groups (A and B), according to the inclusion criteria. Neonates in group A received foot reflexology for 3 min during the first suctioning. The second round of suctioning was performed without the reflexology intervention in this group. In group B, the order of applying reflexology was opposite to that in the group A. Before and after suctioning, SPO2 was recorded as shown by the monitor. During the suctioning procedure, pain was assessed using the NIPS tool. In addition, data were analyzed using SPSS Software.ResultsBased on the results, the mean score of pain was lower in the two groups after suctioning with reflexology (the paired t-test, p < 0.05). Although suctioning improved SPO2, reflexology had no effect on this indicator (p > 0.05).ConclusionReflexology before suctioning is effective in reducing pain in neonates. Additional studies are recommended on changing the time and duration of reflexology and examining the effects.     

经络抚触对早产儿生长发育的影响

目的 探讨经络抚触对早产儿生长发育的影响.方法 将60例早产儿随机分为观察组和对照组各30例,对照组采用国内改良简易抚触法,观察组在此基础上增加经络抚触,2次/d,15 min/次.比较2组早产儿的体质量、身长、摄奶量、睡眠时间等指标的情况.结果 观察组体质量、身长、摄入奶量、睡眠时间、恢复出生体质量时间、胎粪排尽时间显著优于对照组.结论 在国内改良简易抚触法基础上增加经络抚触对早产儿生长发育有明显的促进作用.     

抚触和洗澡对新生儿缺氧缺血性脑病患儿生长发育的影响

目的:探讨抚触和洗澡对新生儿缺氧缺血性脑病(HIE)患儿生长发育的影响。方法:将80例HIE患儿随机分为抚触组和对照组各40例,两组患儿均采用人工喂养并给予综合治疗方案,对照组实施常规护理,观察组在此基础上增加抚触和洗澡,比较两组患儿各项生长指标及神经行为评分。结果:观察组摄奶量、体重、神经行为评分与对照组同日龄患儿比较差异有统计学意义(P<0.05,P<0.01),睡眠时间、胎粪排尽时间、恢复出生体重时间均优于对照组(P<0.05)。结论:在常规护理的基础上增加抚触和洗澡对HIE患儿神经及体格发育有明显的促进作用,值得临床推广。     

冠心病患者血脂和胆红素变化的研究

目的探讨血脂、胆红素与冠心病发生、发展的关系。方法随机抽取139例冠心病患者和118例健康者进行血清甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDI,C）、低密度脂蛋白胆固醇（LDL—C）及胆红素水平检测与对比分析。结果冠心病组患者TG、TC、LDL—C、TG／HDL-C、LDLC／HDL-C显著升高（P〈0．01）,HDL-C、总胆红素（TBil）及间接胆红素（IBil）显著降低（P〈0．01）,且与冠脉病变程度相关;但直接胆红素（DBil）水平无明显差异（P〉0．05）。结论血脂异常和胆红素水平降低与冠心病密切相关。早期干预有可能预防心血管事件的发生。     

The effect of foot massage on the level of consciousness and delirium of intensive care patients: A randomized single-blind controlled trial

IntroductionDepressed level of consciousness and delirium are associated with multiple complications in cognitive, perceptual and sensory functions in the patients of the intensive care units. The present study aimed to determine the effect of foot massage by a nurse and patient's family on the level of consciousness and delirium in patients admitted to the intensive care units (ICU).MethodsThis was a randomized parallel single-blind controlled trial. Seventy-five ICU were assigned in three groups (massage by a nurse, massage by patient's family and control group) by stratified block randomization method. Both feet were massaged with Swedish massage (10 min) once a day for six days by a nurse or patient's family. Delirium and level of consciousness was measured before, and post-intervention.ResultsThe mean level of consciousness in all the three groups increased significantly one-week post-intervention. However, there was no significant difference in the level of consciousness among the three groups during the study. The frequency of delirium in the massage group by the family was 20% before the intervention, which decreased to 12% after intervention. In the massage group by a nurse and control group, 16% of the samples had delirium before the intervention. After the intervention, the prevalence of delirium was 8% in the massage group by a nurse, and it decreased to 12% in the control group, none of which was statistically significant.ConclusionThe use of Swedish foot massage did not change the level of consciousness and delirium of patients admitted to the ICU.     

The effect of massage on cortisol level in infants: A systematic review and meta-analysis

PurposeThis systematic review investigated the effect of massage on cortisol level in infants.MethodsThe search was carried out in electronic databases in June 2021 without time limit. Cochrane guidelines were used to assess the risk of bias. The meta-analysis results were reported as the mean difference with a 95% confidence interval. Heterogeneity of the studies was assessed using I-squared.ResultsFrom 3327 articles, nine articles were eligible and finally six studies were included in the meta-analysis. The mean cortisol level was significantly lower in the massage group than the control group (MD = −0.66; 95% CI: 1.21to-0.10; P = 0.02; I² = 84%; df = 7; Chi² = 43.06,P < 0.00001).DiscussionIt is suggested that further studies be conducted with laboratory measurement, longer time interventions and larger sample sizes to confirm the effect of massage on cortisol level in infants.     

不同部位加温对儿童侧卧位胸腔镜手术术中温度及生理指标的影响

[目的]探讨不同部位加温在儿童侧卧位胸腔镜手术中的应用。[方法]选取某院择期全身麻醉下侧卧位下行胸腔镜手术的63例儿童作为研究对象,随机分为两组。于麻醉诱导完成侧卧位体位摆放后0 min(T0)、30 min(T1)、60 min(T2)、90 min(T3)和手术结束后(T4)5个时间点记录膀胱温度和生理指标。[结果]对下半身肢体进行充分保暖的患儿术中平均动脉压和心率均明显低于上半身保暖的患儿。对上半身肢体进行保暖的患儿术中体温过低的发生率低于下半身肢体保暖的患儿。[结论]在儿童胸腔镜手术中,对上半身加温比下半身加温更加有效,能有效预防儿童胸腔镜手术低体温的发生。     

The effect of massage,wipe bathing and tub bathing on physiological measurements of late premature newborns: A randomized controlled trial

ObjectiveThe aim of this randomized experimental study is to analyze the effect of massage, wipe bathing and tub bathing on physiological measurements of late premature newborns.Designand Methods: This randomized experimental study was conducted on 192 newborns at the gestational week of 34 or higher in the neonatal intensive care unit of a university hospital. The researchers applied massage (n: 48), tub bathing (n: 48), and wipe bathing (n: 48) to the newborns. The control group (n: 48) received no intervention except for the routine clinical practices. The newborns' physiological measurements before, immediately after and 30 min after the interventions were taken and recorded on the “Newborn Follow-up Form.” The newborns’ physiological measurements were assessed by independent evaluators who were blinded to the purpose of the study at different phases across the massage, wipe bathing and tub bathing protocols. The statistical analysis was performed using percentages, means, repeated analysis, variance analysis, Bonferroni analysis.ResultsNo difference was found in the massage, wipe bathing, tub bathing and control groups' mean physiological measurements (pulse, respiration, oxygen saturation, blood pressure, body temperature) (p > 0.05).     

开天门穴位按摩治疗甲亢术前失眠53例效果观察

目的:探讨开天门穴位按摩治疗甲亢术前失眠的效果。方法:将80例甲亢术前失眠患者随机分为对照组27例和观察组53例,对照组给予口服舒乐安定,观察组给予开天门穴位按摩,比较两组的治疗效果。结果:开天门穴位按摩能够缩短患者入睡时间,使其真正的睡眠时间延长,从而提高睡眠质量,与对照组比较有显著性差异(P<0.05)。结论:开天门穴位按摩治疗甲亢术前失眠方法简单,疗效显著,值得推广应用。     

The effect of bilirubin on lipid peroxidation and antioxidant enzymes in cumene hydroperoxide-treated erythrocytes

Recently, it has been suggested that bilirubin may act as a potent biological chain-breaking antioxidant. To observe the effects of free bilirubin on antioxidant reactions in cumene hydroperoxide-treated erythrocytes (15 g hemoglobin/dl), we added bilirubin at four different concentrations (0.5, 1, 5, and 10 mg/dl). We measured the thiobarbituric acid-reactive substance and reduced glutathione levels, and some antioxidant enzyme activities, namely superoxide dismutase, catalase, and glucose-6-phosphate dehydrogenase. Thiobarbituric acid-reactive substance and chemiluminescent signals decreased during the incubation. Superoxide dismutase activities also decreased but not as much as in the control group. Glucose-6-phosphate dehydrogenase activities and reduced glutathione levels increased, but catalase activities remained the same as the control group. Our results suggest that bilirubin — in the concentrations we have used — partially prevented the oxidant effects of cumene hydroperoxide.     

胆红素脑病新生儿血胰岛素样生长因子-1水平的变化及意义

目的探讨胆红素脑病新生儿血清胰岛素样生长因子-1（IGF-1）水平与脑损伤相关性及临床意义。方法研究对象为2009年9月至2012年3月胆红素脑病新生儿36例、足月正常新生儿32例,采用酶联免疫吸附试验（ELISA）检测血清IGF-1水平,对两组新生儿血清IGF-1水平进行比较;同步检测两组患儿间接胆红素水平进行比较。结果胆红素脑病患儿组血清IGF-1浓度为36．12±6．28ng／ml,较正常对照组78．65±17．51ng／ml降低,两组比较差异有统计学意义（P〈0．05）。结论胆红素脑病患儿血清IGF-1浓度显著降低可能与脑损伤密切相关,检测血清IGF-1水平对判断胆红素脑病患儿脑损伤具有临床参考价值。     

The effect of massage therapy on sleep/awake patterns in the preterm infants: A systematic review and meta-analysis

The aim of this systematic review study was investigating the effect of massage on the sleep and awake pattern of premature infants. All articles published in English and Persian until the end of 2020 in databases including Medline, Scopus, Embase, Cochran library, Google scholar and the Farsi databases (SID and IranMedex) were searched. The included studies were randomized, controlled, clinical trials and quasi-experimental studies that investigated the effect of massage therapy or Tactile-kinesthetic stimulation on sleep/awake pattern. The heterogeneity was examined using I². Five studies were entered in this systematic review. The mean total awake time was significantly higher in the massage group compared to the standard care group (SMD = 1.00; 95%CI: 0.09 to 1.90; P = 0.03). However, there was no significant difference between the massage group and standard care group in terms of total sleep. NICU nurses can incorporate massage into daily routine care based on the results of this present review.Registration number in the prosperoCRD42020153546.     

Assessing the effect of sample size, methodological quality and statistical rigour on outcomes of randomised controlled trials on mobilisation, manipulation and massage for low back pain of at least 6 weeks duration

Objectives

To assess the effect of sample size, methodological quality and statistical rigour on outcomes of randomised controlled trials (RCTs) on manual therapy (i.e. manipulation, mobilisation and/or massage) for non-specific low back pain (LBP) of at least 6 weeks duration, and to report results from RCTs with adequate sample size, methodological quality and statistical rigour.

Data sources

MedLine, EMBASE, CINAHL, AMED, Cochrane, PEDro and the library collection of the Chartered Society of Physiotherapy.

Review methods

RCTs were identified that compared manual therapy with a control or alternative intervention in adults with non-specific LBP of at least 6 weeks duration. The sample size, methodological quality (adapted 10-point van Tulder scale) and statistical rigour were then assessed. RCTs were regarded as higher quality if they fulfilled the following three criteria: (a) >40 subjects in the manual therapy group; (b) scoring >5/10 on the Van Tulder scale; and (c) reporting statistical tests that compared the change in the intervention group with the change in the control group.

Results

Ten RCTs were included in the review but only two qualified as higher quality RCTs. Results from smaller trials and lower quality RCTs showed more variation in differences between the intervention and control groups than larger or higher quality trials. Evidence from large, high-quality RCTs with adequate statistical analyses showed that, for improvement in pain and function, a mobilisation/manipulation package is an effective intervention [compared with general practitioner (GP) care], whilst manipulation used in isolation showed no real benefits over sham manipulation or an alternative intervention. No higher quality evidence considering massage was identified.

Conclusions

Many RCTs in the area of manual therapy for LBP have shortcomings in sample size, methodological quality and/or statistical rigour, but there remains evidence from higher quality RCTs to support the use of a manual therapy package, compared with GP care, for non-specific LBP of at least 6 weeks duration.