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1.
患者男,35岁,因"反复发热伴间断腹痛1周"入院.患者1周前出现发热,体温高达39℃,伴畏寒,腹痛,脾区明显,入当地医院诊治,血常规:WBC7.36×109/L,Hb 137 g/L,PLT 29×109/L,生化:ALT 183 U/L,AST 547 U/L,TBIL 30.31μmol/L,DBIL 18.14 μmmol/L,IBIL 12.17μmol/L,TG 1.6 mmol/L,APTT 29.6 s,PT 17.8 s.纤维蛋白原(Fib)1.46 g/L,腹部CT:肝弥漫性增大,脾中度增大,肝门区及肠系膜见多个小结节,较大者10 mm×8 mm,骨髓穿刺见异常组织细胞增多,怀疑恶性组织细胞病,抗感染治疗无效,期间出现畏寒、寒战,体温39.6℃,伴气促,予地塞米松静滴后体温降至正常,气促缓解,2011年1月17日转入我科进一步治疗.  相似文献   

2.
1病例报告例1,男,62岁。主诉乏力、纳差、腹胀伴少尿1月余,于2004年9月21日入院。既往肝硬化病史10余年。入院查体:慢性肝病面容,皮肤及巩膜可见黄染,有肝掌及蜘蛛痣,心、肺听诊无异常,腹部稍膨隆,全腹轻压痛,以左下腹明显,反跳痛阳性,肝右肋下约1~2 cm,剑下2~3 cm,质硬,肝区轻叩痛,脾大,左肋下约4~5 cm,移动性浊音阳性,双下肢无浮肿。实验室检查:WBC 3.6×109/L,N 0.83,RBC 2.18×1012/L,Hb 78g/L,PLT 51×109/L。肝功能:TB IL 78.3μmol/L,ALT 52U/L,AST83U/L,A 32g/L,G 47g/L,AKP 183U/L,-γGT 135U/L,Chol 2.32mmol/L…  相似文献   

3.
1 病历摘要  患者女 ,1 6岁。因腹胀 ,腹围进行性增大 1年入院。既往无肝炎病史 ,家族中无肝病史。体检 :发育差 ,第二性征未发育 ,轻度贫血貌 ,皮肤巩膜无黄染 ,未见蜘蛛痣及肝掌。腹隆起 ,腹壁静脉曲张 ,全腹无压痛 ,肝右肋下 3cm ,剑突下5cm ,质硬 ,无触痛 ,脾左肋下 4cm ,质硬 ,移动性浊音阳性。双下肢无水肿。血红蛋白 1 0 0g/L ,白细胞 7.4× 1 0 9/L ,血小板 73× 1 0 9/L ,总胆红素 1 5 .4 μmol/L ,直接胆红素 6 μmol/L ,总蛋白 87g/L ,白蛋白 32g/L ,谷丙转氨酶 1 2U/L ,谷草转氨酶2 2U/L ,γ 谷氨酰转酞酶 1 5 6U/L ,…  相似文献   

4.
患者,女,82岁,以"反复鼻出血3个月"为主诉入院,否认肝炎等传染性疾病史及外伤史.查体:全腹无压痛及反跳痛,肝肋下2 cm,剑突下4 cm,脾肋下6 cm,质韧.血常规:WBC 3.8×109/L,HGB 111 g/L,MV 108.1/L,MCH 35.2 Pg,PLT 49×1012/L,MPV 9.4 fl.肝功能:总蛋白75 g/L,白蛋白51 g/L,TBIL 21.5 μmol/L,ALT 25 U/L,AST 46 U/L.多肿瘤标志物蛋白芯片检测正常.  相似文献   

5.
女,25岁,农民。因右上腹饱胀,全身皮肤黄染1年余,上腹部包块半年于1992年7月1日入院。患者1年前无明显诱因出现上腹部饱胀、纳差、厌油、无畏寒、发热。全身皮肤黄染逐渐加深,半年后上腹部出现包块,无恶心呕吐。体检:体温36.8℃,脉搏80次/分,呼吸20次/分,血压14/8kPa。皮肤巩膜重度黄染,心肺正常。腹膨隆,腹壁静脉怒张,腹软,右上腹可触及6cm×9cm的囊状包块,质软,有触痛,腹水征阴性,肝脾未触及。实验室检查:血红蛋白83g/L,白细胞10.0×109/L,中性0.71,淋巴0.29。总胆红素540μmol/L,结合胆红素225.6μmol/L,ALT32U/L,乙型肝炎表面抗原阴…  相似文献   

6.
病例 男,62岁.以"发现尿黄5天"为主诉入院.无发热、恶心及厌食等伴随症状.查体:血压150/100mmHg,巩膜轻度黄染,腹软无压痛,肝区无叩击痛,肝肋下未触及.实验室检查:血WBC 13.1×109/L,EO 5.2×109/L,占39.7%.TBIL 36.6μmol/L,DBIL 21.5μmol/L,UDBIL 15.1μmol/L.ALT 88U/L,GGT 201U/L.AFP及CEA阴性.HBsAb阳性,其余4项均阴性.  相似文献   

7.
患者男,44岁,因乏力厌食2年,近1个月加重入院。查体:一般情况尚可,全身皮肤无黄染,心肺听诊未见异常;腹软,无压痛,肝肋下未触及,脾大,肋下10cm,质中等硬度,表面光滑,移动性浊音阴性。实验室检查:WBC21.7×109/L,RBC2.8×1012/L,HGB91g/L;TB95.7μmol/L,DB16.4μmol/L,IB79.3μmol/L,HbsAg阴性。腹部CT检查:肝脏体积缩小,肝裂增宽,脾脏体积明显增大,脾门区可见迂曲的血管影。CT诊断:肝硬化并脾大。彩色多普勒超声:肝脏体积缩小,被膜凹凸不平,肝实质回声增粗、不均;脾轮廓明显增大,约23cm×7.2cm,下缘位于脐下约3cm,实质回声均匀。…  相似文献   

8.
甲型肝炎并发急性出血性白质脑病1例   总被引:1,自引:1,他引:0  
王朝光 《新医学》1998,29(4):214
女,30岁。因发热、眼黄、纳差4天于1995年12月28日入院。查体:体温38℃,脉搏90次/分,呼吸18次/分,血压16/10kPa。神清。无肝掌及蜘蛛痣,巩膜轻度黄染,两侧瞳孔等大等圆,对光反射存在,球结膜无水肿。颈软。心、肺、腹无异常。肝肋下3cm,剑突下3.5cm,质软,有叩击痛和压痛,脾肋下未触及,无移动性浊音。四肢肌力及肌张力正常,病理反射均未引出。实验室检查:血白细胞5.4×109/L,中性0.73,淋巴0.25,嗜酸0.02。肝功能:ALT800U,血清总胆红素94μmol/L,碱性磷酸酶150U。乙型肝炎病毒标志物均阴性,甲型肝炎病毒抗体IgM阳性。患者入院后按病毒性肝…  相似文献   

9.
例1,女,70岁.因“发热伴腹泻1周”于2011年6月3日入院.患者于1周前因发热伴腹泻至当地医院就诊,予以补液抗感染等治疗后未见好转.入院查体:体温:39.4℃,血压:114/76 mm Hg(1 mm Hg =0.133 kPa).神志清楚,轻度贫血貌,全身皮肤、黏膜可见多处瘀斑及出血点,左侧颌下可触及数枚黄豆大小淋巴结.心、肺未见明显异常,腹平软,肝、脾肋缘下未及,双下肢无水肿,四肢关节无畸形.血常规:WBC 1.3×109/L,中性粒细胞0.81×109/L,HGB100 g/L,PLT 6×109/L.尿常规:尿蛋白(++).血生化:AL441.8 U/L, AST 321.8U/L,三酰甘油(TG)2.72 mmol/L,LDH 1226 U/L,血清铁蛋白(SF) 15 400 μg/L.  相似文献   

10.
患者,男,28岁。因发热、消瘦、乏力1个月入院。体格检查:体温39℃,消瘦,贫血貌,皮肤、黏膜苍白,浅表淋巴结无肿大。牙龈无增生。胸骨无压痛。双肺无干、湿啰音,心律整齐,无杂音。肝肋下未扪及,脾肋下5cm,质软。血常规:血红蛋白73g/L,红细胞26×1012/L,白细胞32×109/L,淋巴  相似文献   

11.
Objective: To identify patterns of nonfatal and fatal penetrating trauma among children and adults in New Mexico using ED and medical examiner data.
Methods: The authors retrospectively sampled in 5-year intervals all victims of penetrating trauma who presented to either the state Level-1 trauma center or the state medical examiner from a 16-year period (1978–1993). Rates of nonfatal and fatal firearm and stabbing injury were compared for children and adults.
Results: Rates of nonfatal injury were similar (firearm, 34.3 per 100,000 person-years; stabbing, 35.1). However, rates of fatal injury were significantly different (firearm, 21.9; stabbing, 2.7; relative risk: 8.2; 95% confidence interval: 5.4, 12.5). From 1978 to 1993, nonfatal injury rates increased for children (p = 0.0043) and adults (p < 0.0001), while fatal penetrating injury remained constant. The increase in nonfatal injury in children resulted from increased firearm injury rates. In adults, both stabbing and firearm nonfatal injury rates increased.
Conclusions: Nonfatal injury data suggest that nonfatal violence has increased; fatal injury data suggest that violent death rates have remained constant. Injury patterns vary by age, mechanism of trauma, and data source. These results suggest that ED and medical examiner data differ and that both are needed to guide injury prevention programs.  相似文献   

12.
Three supplementary perspectives are presented arguing that interprofessional collaboration is both necessary and desirable. Nonetheless, there are often too many serious intra-professional barriers and obstacles to interprofessional collaboration to make it successful. Some of these barriers, it is argued and illustrated, are found in the multiple ways in which professional identity is tacitly acquired and embodied in the practitioners' habitual, everyday practice. The paper then explores ways in which reflection, especially Second order reflection, can help to elucidate and overcome these obstacles, as well as increasing professional adaptability and competence.  相似文献   

13.
This is a new method for the determination of creatine kinase isoenzyme MB activity in serum. The method uses direct activity measurement of creatine kinase B subunit activity after blocking of CK-M subunit activity by inhibiting antibodies. The test takes no longer than 15 min. The method yields an intra-serial C.V. of 2.0-12.9%, and a C.V. from day to day of 5.5%. The detection limit is 3.4 U/l creatine kinase MB. In the 95 cases with proven myocardial infarction several types of creatine kinase MB activity kinetics could be determined. The percentage of creatine kinase MB of peak CK-total is 6-25%, with a mean of 11.1%. The amount of creatine kinase MB with respect to total CK activity after reinfarction is higher than the amount after initial infarction.  相似文献   

14.
目的 探讨手转胎头术失败的原因与分娩结局.方法 选择2008年1月至2010年12月于我院住院分娩的持续性枕横位、枕后位产妇198例,根据行手转胎头术后结果分为成功组126例、失败组72例.比较两组分娩结局,对比分析失败原因.结果 失败组胎儿体质量≥3500 g的发生率[76.4%(55/72)]明显高于成功组[31.7%(40/126)],差异有统计学意义(x2=30.177,P=0.001)、失败组宫缩乏力发生率[58.3%(42/72)]高于成功组[38.1% (48/126)],差异有统计学意义(x2=7.569,P=0.006)、失败组骨盆临界或轻度狭窄发生率[38.9% (28/72)]高于成功组[23.8%(30/126)],差异有统计学意义(x2 =5.030,P=0.002)、失败组手转胎头时机不当(宫口开大<6 cm、胎头位于坐骨棘上及宫口开大8~10 cm、胎头位于坐骨棘下≥2 cm)发生率[61.1%(44/72)]高于成功组[38.9%(49/126)],差异有统计学意义(x2=9.084,P=0.003).失败组母儿并发症(产后出血、产褥病率、胎儿窘迫、新生儿窒息)发生率高于成功组(x2 =9.586,P=0.002、x2=9.334,P=0.002、x2=5.910,P=0.015、x2=5.240,P=0.022)、失败组剖宫产发生率[72.2%(52/72)]明显高于成功组[34.1 %(43/126),x2=26.641,P=0.001)].结论 手转胎头术能使难产变顺产,降低剖宫产率,减少母儿并发症,但须积极预防、处理导致手转胎头术失败的原因,对矫正失败后继续矫正及试产应慎重.  相似文献   

15.
ABSTRACT

The Cochrane Library of Systematic Reviews is published quarterly as a DVD and monthly online. The January 2011 issue (first quarterly DVD for 2011) contains 4515 complete reviews, 1985 protocols for reviews in production, and 13,521 one-page summaries of systematic reviews published in the general medical literature. In addition, there are citations of 641,000 randomized controlled trials, and 14,018 cited papers in the Cochrane methodology register. The health technology assessment database contains over 9300 citations. One hundred and seven new reviews have been published in the last 3 months, of which five have potential relevance for practitioners in pain and palliative medicine.  相似文献   

16.
The Department of Veterans Affairs (VA) in the USA operates a network of 172 medical centres which all utilize a hospital information system (HIS) which has been developed and is currently maintained by the VA. During the past several years, an image management and communication module has been developed, installed and clinically utilized at the Washington DC and Maryland VA Medical Centres. This image management and communication system, referred to as the decentralized hospital computer program (DHCP) imaging system, is fully integrated with a commercial picture archiving and communication system (PACS). The system is utilized to capture, archive, and display all images generated within the hospital including radiology, nuclear medicine, pathology, endoscopy, bronchoscopy, and dermatology, intraoperative photographs, ECG data, and a limited number of paper documents. The ultimate goal of the project is to have all patient text and image data available at any clinical workstation to any authorized user anywhere within the network of medical centres. Clinical requirements for an imaging workstation include ease of use, rapid and reliable access to the complete set of patient information, and images which are of acceptable quality to meet the requirements of the user and the subspecialty. Patient confidentiality and data security must be safeguarded at all times. Integration of the images with the remainder of the patient's database was found to be critical to the success of the project. The experience at the Washington and Maryland facilities suggests that an imaging system that is successfully integrated with a hospital information system can provide substantial clinical and economic benefits both within and among medical centres. Clinical acceptance and utilization of the system has been excellent, particularly in diagnostic radiology where DHCP Imaging has been interfaced to a commercial PAC system. Based upon this initial experience, the VA has begun to deploy the system throughout its large network of medical centres.  相似文献   

17.
18.
目的 探讨俯卧位通气对高海拔地区肺复张术(RM)治疗无效急性呼吸窘迫综合征(ARDS)患者的治疗作用.方法 从海拔2260m的地区医院筛选RM治疗无效的41例ARDS患者[平均氧合指数( PaO2/FiO2)较RM前升高<20%视为RM无效],依不同病因分为肺内源性ARDS组(ARDSp组)和肺外源性ARDS组(ARDSexp组),每组再按信封法随机分为俯卧位组和仰卧位组,即ARDSp俯卧位组(11例)、ARDSp仰卧位组(9例)、ARDSexp俯卧位组(10例)、ARDSexp仰卧位组(11例).在通气前及通气1、2、3、4h监测动脉血氧分压( PaO2)、PaO2/FiO2、静态顺应性(Cst)、气道阻力(Raw)的变化.结果 通气lh时,ARDSexp俯卧位组PaO2/FiO2( mm Hg,l mm Hg=0.133 kPa)即较通气前显著升高(157.4±40.6比129.3±48.7,P<0.05),并随通气时间延长呈持续增高趋势,4h达峰值(219.1 ±41.1);且ARDSexp俯卧位组通气3h内PaO2/FiO2较其他3组显著增高,另3组间则差异无统计学意义.ARDSp俯卧位组、ARDSexp俯卧位组通气4h时PaO2/FiO2均较相应仰卧位组显著增高(208.8±39.7比127.4±47.1,219.1±41.1比124.9±50.8,均P<0.05).4组通气前后Cst无显著改变,各组间差异也无统计学意义.ARDSp俯卧位组通气4h时Raw(cmH2O·L-1·s-1)较通气前显著降低(6.8±1.7比10.7±1.8,P<0.05),且明显低于其他3组;其他3组各时间点Raw组内及组间比较差异均无统计学意义.结论 俯卧位通气作为ARDS机械通气重要策略之一,可以改善RM无效高原ARDS患者的氧合,为抢救患者赢得宝贵的时间.  相似文献   

19.
20.
Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high spatial and temporal resolution and high signal-to-noise ratio (SNR). In this paper, in-vivo experiments were performed in anesthetized normal and infarcted mice (one day after left anterior descending coronary artery [LAD] ligation) using a high-resolution (30 MHz) ultrasound system (Vevo 770, VisualSonics Inc., Toronto, ON, Canada). Radiofrequency (RF) signals of the left ventricle (LV) in longitudinal (long-axis) view and the associated electrocardiogram (ECG) were simultaneously acquired. Using a retrospective ECG gating technique, 2-D full field-of-view RF frames were acquired at an extremely high frame rate (8 kHz) that resulted in high-quality incremental displacement and strain estimation of the myocardium. The incremental results were further accumulated to obtain the cumulative displacements and strains. Two-dimensional and M-mode displacement images and strain images (elastograms), as well as displacement and strain profiles as a function of time, were compared between normal and infarcted mice. Incremental results clearly depicted cardiac events including LV contraction, LV relaxation and isovolumetric phases in both normal and infarcted mice, and also evidently indicated reduced motion and deformation in the infarcted myocardium. The elastograms indicated that the infarcted regions underwent thinning during systole rather than thickening, as in the normal case. The cumulative elastograms were found to have higher elastographic SNR (SNR(e)) than the incremental elastograms (e.g., 10.6 vs. 4.7 in a normal myocardium, and 6.0 vs. 2.4 in an infarcted myocardium). Finally, preliminary statistical results from nine normal (m = 9) and seven infarcted (n = 7) mice indicated the capability of the cumulative strain in differentiating infracted from normal myocardia. In conclusion, myocardial elastography could provide regional strain information at simultaneously high temporal (>/=0.125 ms) and spatial ( approximately 55 microm) resolution as well as high precision ( approximately 0.05 microm displacement). This technique was thus capable of accurately characterizing normal myocardial function throughout an entire cardiac cycle, at the same high resolution, and detecting and localizing myocardial infarction in vivo.  相似文献   

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