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1.
【目的】探讨单侧鼻窦发病的规律。【方法】回顾性分析了1998年1月至2004年10月间收治的6266例鼻窦疾病患者中793例单侧鼻窦疾病患者的诊断资料。【结果】793例患者中慢性鼻窦炎者425例,占53.6%;鼻窦真菌病102例,占12.9%;鼻窦乳头状瘤51例,占6.4%;鼻窦囊肿117例,占14.8%;上颌窦出血坏死性息肉23例,占42、9%;上颌骨骨纤维组织异常增殖症2例.占0.25%;骨瘤11例,占1.4%;上颌窦血管瘤2例,占0.25%;脑膜或脑膜-脑膨出5例,占0.6%;恶性肉芽肿19例,占2.4%;恶性肿瘤36例,占4.6%。【结论】有近半数(46.4%)的单侧鼻窦疾病患者所患的疾病为非普通的性性炎症性疾病,这对于指导临床诊断思维有重要意义。  相似文献   

2.
目的 :通过对鼻内窥镜手术不同术式的治疗效果的观察 ,探讨慢性上颌窦炎、鼻息肉的治疗方法。方法 :75例慢性鼻窦炎及鼻息肉患者随机分成两组 ,治疗组 4 0例 ,清除中鼻道病变及异常结构不扩大上颌窦自然开口。对照组 35例术中切除中鼻道病变及异常结构的同时扩大上颌窦自然开口。术后随访 1年以上。结果 :两组病例治愈率无明显差异 (χ2 =0 .0 3 P >0 .0 5 ) ,治疗组减少手术操作 ,减少并发症。结论 :慢性鼻窦炎及鼻息肉手术中主要清除窦口周围异常结构及病变 ,上颌窦自然开口如无明显狭窄不必扩大  相似文献   

3.
BACKGROUND: Clarithromycin exhibits anti-inflammatory as well as antimicrobial activity, leading to decreased symptoms of asthma and chronic sinusitis. The mode of anti-inflammatory effects of clarithromycin on inflammatory cells is not well understood. We hypothesized that clarithromycin inhibits inflammatory cell mediator release and survival. METHODS: We investigated the effects of this drug on survival and mediator release from mast cells, eosinophils and neutrophils. RESULTS: Human eosinophil and neutrophil respiratory burst was inhibited by up to 54% after 1-2 h pretreatment with 100 microg/ml clarithromycin. Similar doses of erythromycin did not affect respiratory burst responses in these cells. Clarithromycin at doses of up to 100 microg/ml had no effect on granule-derived mediators released from mast cells and neutrophils. However, we found that clarithromycin (100 microg/ml) induced cell death in mast cells and eosinophils after 16-48 h incubation. CONCLUSION: Clarithromycin inhibited inflammatory cell mediator release and survival, which may enhance its ability to reduce the symptoms of chronic sinusitis and asthma.  相似文献   

4.
This case report demonstrates that pulsed ultrasound (US), when used for a total of 20 treatment sessions, provided symptom relief to a patient with chronic rhinosinusitis (CRS). A 16-year-old boy with a 12-month history of rhinosinusitis and candidate for sinus surgery was referred for ultrasound therapy. He presented with facial pain/pressure, nasal obstruction, and postnasal drip (total sinusitis score=7). On computed tomographic (CT) scanning, the total opacification of the right maxillary sinus was observed. The ostiomeatal complex was occluded (total CT score=6). Pulsed ultrasound was administered three times a week, every other day. After 10 treatment sessions, his symptoms were resolved with exception of nasal obstruction being mild (total sinusitis score=2). On CT scan, right maxillary sinus showed partial improvement (total CT score=2). After additional 10 treatments, the nasal obstruction was resolved, and follow-up CT scan of his sinuses showed that right maxillary sinus was clear and normal. At 6-month follow-up, the positive effects were maintained and the patient reported no recurrence of symptoms. Twenty sessions of pulsed ultrasound therapy eradicated the CRS and resolved the symptoms.  相似文献   

5.
目的探讨鼻用激素和克拉霉素联合用药对慢性鼻-鼻窦炎(CRS)的治疗效果。方法将130例CRS患者随机分成3组,即布地奈德鼻喷雾剂组(42例)、克拉霉素组(45例)和布地奈德鼻喷雾剂联合克拉霉素组(43例),疗程均为12周,治疗前后采用主观症状自评治疗效果及Lund-Mackey鼻窦CT评分。结果布地奈德鼻喷雾剂联合克拉霉素组自评得分[(2.39±0.58)分]显著低于布地奈德鼻喷雾剂组[(3.98±1.57)分]和克拉霉素组[(4.12±1.35)分],差异有统计学意义(P<0.05),Lund-Mackey鼻窦CT评分布地奈德鼻喷雾剂联合克拉霉素组[(2.61±0.91)分]显著低于布地奈德鼻喷雾剂组[(4.33±1.05)分]和克拉霉素组[(4.37±0.92)分],差异有统计学意义(P<0.05)。结论布地奈德鼻喷雾剂和克拉霉素联合用药治疗CRS临床疗效较好。  相似文献   

6.
目的:通过比较慢性鼻窦炎治疗前后鼻息肉组织及术腔黏膜上皮、固有层和分泌物中主要碱性蛋白及弹性蛋白酶表达情况,探讨鼻内镜术后应用博科喷鼻剂、雷诺考特喷鼻剂对术腔黏膜组织中主要碱性蛋白及弹性蛋白酶表达的影响,用以评价局部喷鼻剂在术后术腔恢复中的作用。方法:采用免疫组织化学和Axioplan 2显微图像分析系统检测治疗前后鼻息肉组织及术腔黏膜中主要碱性蛋白及弹性蛋白酶的表达情况。结果:(1)手术日及术后1周鼻息肉组织的上皮层、固有层和分泌物内的主要碱性蛋白及弹性蛋白酶平均阳性表达,治疗组和对照组比较差异无统计学意义(P>0.05);术后4周及术后8周与对照组相比差异均有统计学意义(P<0.05);(2)2组主要碱性蛋白平均阳性表达术后4周与1周相比,术后8周与4周相比差异均有统计学意义(P<0.05);(3)2组术后1周与手术日相比弹性蛋白酶表达增加,差异有统计学意义(P<0.05),术后8周与术后4周相比弹性蛋白酶表达减少,差异有统计学意义(P<0.05);治疗组术后4周与术后1周相比弹性蛋白酶表达显著减少,但对照组弹性蛋白酶表达差异无统计学意义(P>0.05)。结论:鼻内镜术后博科和雷诺考特喷鼻剂联合应用在降低...  相似文献   

7.
目的探讨窦口鼻道复合体病变及解剖变异与慢性上颌窦炎的关系.方法对CT诊断的52例单侧慢性上颌窦炎进行两侧对比分析.结果患侧与健侧筛泡截面分别为(77.75±33.51) mm2和(34±20.27) mm2(P<0.01).两侧分别有19个及10个大筛泡.患侧伴有32组筛窦炎,对侧21组.鼻息肉11例,单发于上颌窦炎侧9例,对侧仅1例,双侧1例.结论大筛泡、前中组筛窦炎症、鼻息肉与慢性上颌窦炎有关.  相似文献   

8.
Effect of nasogastric tubes on the nose and maxillary sinus   总被引:2,自引:0,他引:2  
OBJECTIVE: To estimate the proportion of patients who develop radiologic evidence of maxillary sinus inflammation among those who are maintained on nasogastric (NG) tubes after major surgery. DESIGN: Prospective case series. SETTING: Patients were drawn from the general surgical and ear, nose, and throat units of a tertiary care hospital. METHOD: All patients undergoing major surgery with or without a concurrent tracheostomy, in whom an NG tube was retained for greater than or equal to 48 hrs, were examined clinically and radiologically for evidence of maxillary sinus inflammation. RESULTS: Sixty-five patients were studied. Twenty patients had a concurrent tracheostomy and 45 patients were without tracheostomy. Only 10% of the patients in the tracheostomy group developed radiologic evidence of sinus inflammation, as compared with 50% in the nontracheostomy group (p less than .05). The proportion of patients who developed clinical evidence of rhinitis was about 75% in either group. However, none of the patients in the study had clinical evidence of maxillary sinusitis. There was no correlation between the age of the patient, sex, use of broad-spectrum antibiotics, or duration of NG intubation with the onset of sinus inflammation. CONCLUSIONS: The presence of NG tubes predisposes to nasal and maxillary sinus inflammation. Sinonasal symptoms of clinical sinusitis may not be present even when radiologic evidence of inflammation is evident. In patients with tracheostomy, the frequency of maxillary sinus inflammation is significantly lower than in those patients without tracheostomy.  相似文献   

9.
Dean Michael Clerico  MD 《Headache》1995,35(4):185-192
Headache associated with acute sinusitis is a well-recognized entity; the diagnosis is easily made due to the associated nasal and sinus symptoms. However, the phenomenon of referred headache from chronic sinusitis or intranasal abnormalities or both without upper respiratory symptoms is not well understood. Only recently have the nasal and sinus cavities been adequately visualized by both the human eye and radiographic techniques; a fact that may account for the historic neglect in considering this region a factor in headache etiology. Modern techniques employed in the workup of sinusitis, namely the use of rigid nasal endoscopes and coronal-plane CT scanning, have greatly enhanced the clinician's ability to evaluate and diagnose pathology in this area. This report describes a series of patients presenting with various primary headache syndromes without significant nasal or sinus symptoms who failed to respond to conventional antiheadache therapy. On nasal endoscopic and coronal CT examinations, various intranasal and sinus abnormalities were found (either anatomic variations or subclinical inflammation). Medical and/or surgical therapy addressing the sinonasal pathology resulted in improvement in every case, ranging from decreased severity of attacks to total resolution of headaches. A model explaining the possible mechanism of referred vascular-type headache from sinus and nasal origin is proposed.  相似文献   

10.
Sinusitis.     
R L Crumley 《Primary care》1976,3(2):293-299
The treatment of acute bacterial sinusitis is medical, the regimen including oral and nasal decongestants and antibiotics. Progression to chronic sinusitis can sometimes be prevented by periodic sinus washings until the acute process subsides. Sinus x-ray examinations are important in follow-up when symptoms or signs persist.  相似文献   

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