Investigations into the FLG Null Phenotype: Showcasing the Methodology for CRISPR/Cas9 Editing of Human Keratinocytes

1. Download : Download high-res image (405KB)
2. Download : Download full-size image

     

Licoricidin Abrogates T-Cell Activation by Modulating PTPN1 Activity and Attenuates Atopic Dermatitis In Vivo

1. Download : Download high-res image (180KB)
2. Download : Download full-size image

     

TBX3 Promotes Melanoma Migration by Transcriptional Activation of ID1, which Prevents Activation of E-Cadherin by MITF

1. Download : Download high-res image (127KB)
2. Download : Download full-size image

     

Assessment of Spatial and Temporal Variation in the Skin Transcriptome of Atopic Dermatitis by Use of 1.5 mm Minipunch Biopsies

1. Download : Download high-res image (184KB)
2. Download : Download full-size image

     

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

1. Download : Download high-res image (175KB)
2. Download : Download full-size image

     

Integrated Analysis of Single-Cell and Spatial Transcriptomics in Keloids: Highlights on Fibrovascular Interactions in Keloid Pathogenesis

1. Download : Download high-res image (318KB)
2. Download : Download full-size image

     

MXD4/MAD4 Regulates Human Keratinocyte Precursor Fate

1. Download : Download high-res image (188KB)
2. Download : Download full-size image

     

TGFβ2 Upregulates Tyrosinase Activity through Opsin-3 in Human Skin Melanocytes In Vitro

1. Download : Download high-res image (105KB)
2. Download : Download full-size image

     

Possible Involvement of Antigen-Presenting Cells Expressing the Macrophage Galactose-Type C-Type Lectin in Inflammatory Skin Diseases

1. Download : Download high-res image (144KB)
2. Download : Download full-size image

     

Cyclin-Dependent Kinase 7 Promotes Th17/Th1 Cell Differentiation in Psoriasis by Modulating Glycolytic Metabolism

1. Download : Download high-res image (208KB)
2. Download : Download full-size image

     

Quantitative Proteomics Identifies Reduced NRF2 Activity and Mitochondrial Dysfunction in Atopic Dermatitis

1. Download : Download high-res image (291KB)
2. Download : Download full-size image

     

Hemidesmosomes and Focal Adhesions Treadmill as Separate but Linked Entities during Keratinocyte Migration

1. Download : Download high-res image (128KB)
2. Download : Download full-size image

     

S100A9 Drives the Chronification of Psoriasiform Inflammation by Inducing IL-23/Type 3 Immunity

1. Download : Download high-res image (392KB)
2. Download : Download full-size image

     

Dupilumab shows long-term safety and efficacy in patients with moderate to severe atopic dermatitis enrolled in a phase 3 open-label extension study

1. Download : Download high-res image (193KB)
2. Download : Download full-size image

     

Galectin-1 Expression in CD8+ T Lymphocytes Controls Inflammation in Contact Hypersensitivity

1. Download : Download high-res image (427KB)
2. Download : Download full-size image

     

Effects of ruxolitinib cream on pruritus and quality of life in atopic dermatitis: Results from a phase 2, randomized,dose-ranging,vehicle- and active-controlled study

1. Download : Download high-res image (370KB)
2. Download : Download full-size image

     

BMPR1a Is Required for the Optimal TGFβ1-Dependent CD207+ Langerhans Cell Differentiation and Limits Skin Inflammation through CD11c+ Cells

1. Download : Download high-res image (265KB)
2. Download : Download full-size image

     

Germline Mutation of PLCD1 Contributes to Human Multiple Pilomatricomas through Protein Kinase D/Extracellular Signal–Regulated Kinase1/2 Cascade and TRPV6

1. Download : Download high-res image (112KB)
2. Download : Download full-size image

     

Chromosomal Aberrations Accumulate during Metastasis of Virus-Negative Merkel Cell Carcinoma

1. Download : Download high-res image (228KB)
2. Download : Download full-size image

     

Differential Changes in Inflammatory Mononuclear Phagocyte and T-Cell Profiles within Psoriatic Skin during Treatment with Guselkumab vs. Secukinumab

1. Download : Download high-res image (458KB)
2. Download : Download full-size image