首页 | 本学科首页   官方微博 | 高级检索  
相似文献
 共查询到20条相似文献,搜索用时 46 毫秒
1.
泌尿生殖道支原体感染临床耐药性分析   总被引:19,自引:2,他引:17  
目的 分析解脲脲原体(UU)和人型支原体(MH)在非淋菌性尿道炎 (宫颈炎 )患者中的感染情况及耐药现状。方法 采用珠海浪峰公司生产的支原体培养鉴定药敏试剂盒进行培养及药敏试验。结果 184例支原体培养阳性标本中,UU阳性 139例(75. 5% ),MH阳性 15例(8. 2% ),UU+MH阳性 30例 (16. 3% )。对红霉素、四环素和阿奇霉素耐药率分别为 87. 5%, 83. 7%, 58. 2%;对强力霉素、美满霉素、交沙霉素的耐药率分别为 6. 0%, 7. 1%, 15. 2%。结论 UU感染是支原体感染的主要病原体;临床治疗应首选强力霉素、美满霉素、交沙霉素。  相似文献   

2.
目的了解牡丹江地区性病门诊女性患者的泌尿生殖道解脲支原体(UU)和人型支原体(MH)感染及耐药情况,指导临床合理用药。方法对509例疑为非淋菌性宫颈炎患者的生殖道标本进行UU和MH培养及药敏鉴定。结果生殖道支原体感染235例,感染率为46.17%。其中单纯UU阳性202例(39.69%)、MH阳性11例(2.16%),UU和MH同时阳性22例(4.32%)。8种抗生素的敏感程度依次为交沙霉素、强力霉素、克拉霉素、四环素、阿奇霉素、红霉素、氧氟沙星、环丙沙星。结论 UU是本地区性病门诊女性患者生殖道支原体感染的主要病原体,治疗上首选交沙霉素、强力霉素、克拉霉素。加强支原体的培养与药敏检测研究,将有助于指导临床诊断及合理用药。  相似文献   

3.
目的:了解本地区泌尿生殖道解脲支原体(UU)和人型支原体(MH)感染情况以及对抗生素的耐药性,指导临床合理用药。方法:采用珠海浪峰生物技术公司生产的支原体培养、鉴定、计数药敏试剂盒对1000例标本进行培养、鉴定和药敏试验。结果:支原体总阳性感染率为40.5%(405/1000),其中UU305株,阳性率为30.5%;MH18株,阳性率为1.8%;UU和MH混合感染82株,阳性率为8.2%。对抗生素耐药情况,喹诺酮类药物耐药性最高(环丙沙星79.0%、司帕沙星60.7%、可乐必妥52.8%),大环内酯类药物耐药率在3%-31%(交沙霉素3.2%、阿齐霉素14.3%、克拉霉素19.7%、罗红霉素27.1%、环酯红霉素17.2%、红霉素30.6%),四环素类药物耐药率最低在1%-5%(强力霉素为1.7%、美满霉素3.4%)。结论:对泌尿生殖道UU和MH感染患者,四环素和大环内酯类几种抗生素耐药性较低,仍可作本地区一线抗UU和MH药物。  相似文献   

4.
目的了解泌尿生殖道支原体感染的菌种类型及耐药现状,为临床医师合理用药提供依据。方法采用珠海浪峰生物技术有限公司生产的支原体培养、鉴定药敏试剂盒进行培养及药敏试验。结果 133例支原体培养阳性标本中,检出UU100例(75.2%),Mh11例(8.3%),UU+Mh22例(16.5%)。对强力霉素、美满霉素、交沙霉素的耐药率分别为7.5%,9.8%和16.5%,对红霉素、四环素、阿奇霉素的耐药率分别为85.7%,82.7%和60.2%。结论在泌尿生殖道中UU感染率最高;临床治疗应首选强力霉素、美满霉素、交沙霉素。  相似文献   

5.
宫颈炎及健康妇女支原体感染及耐药情况分析   总被引:1,自引:0,他引:1  
采用病例对照研究方法,分析宫颈炎及健康女性解脲脲原体(UU)、人型支原体(MH)感染及两种病原体耐药情况.结果:宫颈炎患者组UU感染率为61.18%(52/85),MH感染率为4.71%(4/85);健康女性UU感染率为54.67%(82/150),MH感染率为5.33%(8/150),两组UU、MH感染率无显著性差异(P>0.05).两组UU对红霉素、四环素、环丙沙星均不敏感,对氧氟沙星、阿奇霉素、克拉霉素耐药性也较高;MH感染者对原始霉素敏感,其次是多西环素和交沙霉素.UU和MH可能不是宫颈炎的致病因素,可能仅在宫颈中定植.对UU和MH的治疗需结合情况而定.  相似文献   

6.
目的 了解非淋菌性尿道炎患者衣原体 ,支原体感染的状况及抗生素抗菌作用 ,为临床治疗支原体感染和抗生素选择提供参考依据。方法 采用英国DXOID公司衣原体抗原抗体检测板及法国BIOMERIEUX公司MY COPLASMAIST试剂盒对 42例非淋菌性尿道炎 (NGU)患者的分泌物 ,前段尿、前列腺液等标本进行衣原体 (CT)检测及支原体培养鉴定、计数及药敏试验。结果 解脲支原体 (UU)检出率最高 30 9% ,人型支原体 (MH)检出率最低 14 3% ,解脲支原体 (UU)与人型支原体 (MH)合并感染最常见 ,UU与CT合并感染也常见 ,MH与CT合并感染较少 ,共检出 15株支原体阳性株对强力霉素 ,交沙霉素 ,氧氟沙星 ,红霉素 ,四环素 ,原始霉素的敏感率分别为 5 3 3% ,80 % ,33 3% ,86 7% ,33 3% ,86 7% ,耐四环素的UU及MH对红霉素及强力霉素有较高交叉耐药率分别为 70 % ,6 0 %。结论 支原体、衣原体是引起非淋菌性尿道炎的重要的病原菌 ,对其进行检测及耐药性监测 ,对指导临床治疗具有重要意义。  相似文献   

7.
非淋菌性尿道炎患者支原体培养及药敏分析   总被引:20,自引:2,他引:18  
目的了解非淋菌性泌尿生殖道感染患者解脲脲原体(UU)和人型支原体(MH)感染及耐药情况,以指导临床合理用药。方法采用支原体培养、鉴定、药敏一体化试剂盒对850例非淋菌性尿道炎(NGU)患者进行支原体培养及药敏试验。结果850例中支原体阳性275例,阳性率为32.35%,其中UU阳性210例(24.76%),MH阳性19例(2.24%),混合感染46例(5.4%)。对支原体敏感性最高的是强力霉素(86.18%),其次依次为交沙霉素(82.18%)、美满霉素(81.46%)、罗红霉素(70.18%)、氧氟沙星(65.09%)、阿奇霉素(60.00%)、克林霉素(58.91%)。结论支原体在体外对多种抗菌药物耐药现象严重,治疗宜首选强力霉素、交沙霉素、美满霉素。  相似文献   

8.
目的了解本地区女性阴道炎患者的支原体感染情况及耐药现状,为临床合理应用抗生素提供参考。方法采用支原体培养鉴定药敏试剂盒进行支原体培养鉴定及药敏试验。结果536例阴道炎患者中支原体阳性215例,阳性率为40.1%。其中UU阳性161例(30.0%);MH阳性17例(3.2%);UU和MH混合感染37例(6.9%)。对强力霉素、交沙霉素、美满霉素、罗红霉素、氧氟沙星、阿奇霉素、克林霉素耐药率分别为14.0%,15.8%,19.5%,30.2%,34.4%,43.7%,45.6%。结论阴道炎患者支原体感染率为40.1%,UU是支原体感染的主要病原体,临床治疗首选强力霉素、交沙霉素和美满霉素。  相似文献   

9.
目的 了解临沧市泌尿生殖道解脲支原体(UU)和人型支原体(MH)感染及药敏情况以指导临床合理用药.方法 使用支原体分离培养药敏试剂盒,对2010年6月~2011年12月我院可疑支原体感染708例患者的泌尿生殖道标本进行UU和MH检测,并测定其对12种抗生素的敏感性.结果 708例样本中,UU阳性者675例,MH阳性者206例,两者同时阳性者174例.UU最敏感的抗生素是强力霉素,其次是美满霉素和交沙霉素,耐药最高的是红霉素和环丙沙星;MH最敏感的是强力霉素和美满霉素,MH耐药最高的是罗红霉素和红霉素.结论 临床用药应该充分考虑本地区耐药株的流行情况,最好是按照药敏结果给予合理用药.  相似文献   

10.
目的探讨性病门诊就诊非淋菌性泌尿生殖道感染者(NGU)的支原体感染及耐药情况。方法采用支原体诊断试剂盒对965例拟诊为NGU的患者的分泌物进行培养、鉴定以及抗生素药物敏感试验。结果 965例患者中支原体培养阳性436例(45.18%),其中解脲支原体(UU)阳性333例(34.51%),人型支原体(MH)阳性28例(2.90%),UU合并MH阳性75例(7.77%)。女性支原体阳性率高于男性(P0.01),UU感染率高于MH(P0.01)。UU对美满霉素、强力霉素、克拉霉素、交沙霉素以及阿奇霉素较为敏感,UU合并MH以及MH感染均对美满霉素及强力霉素敏感。结论本组NGU感染以UU为主,美满霉素及强力霉素为首选药物。  相似文献   

11.
It is generally believed that ablative laser therapies result in prolonged healing and greater adverse events when compared with nonablative lasers for skin resurfacing. To evaluate the efficacy of ablative laser use for skin resurfacing and adverse events as a consequence of treatment in comparison to other modalities, a PRISMA‐compliant systematic review (Systematic Review Registration Number: 204016) of twelve electronic databases was conducted for the terms “ablative laser” and “skin resurfacing” from March 2002 until July 2020. Studies included meta‐analyses, randomized control trials, cohort studies, and case reports to facilitate evaluation of the data. All articles were evaluated for bias. The search strategy produced 34 studies. Of 1093 patients included in the studies of interest, adverse events were reported in a total of 106 patients (9.7%). Higher rates of adverse events were described in nonablative therapies (12.2% ± 2.19%, 31 events) when compared with ablative therapy (8.28% ± 2.46%, 81 events). 147 patients (13.4%) reported no side effects, 68 (6.22%) reported expected, transient self‐resolving events, and five (0.046%) presented with hypertrophic scarring. Excluding transient events, ablative lasers had fewer complications overall when compared with nonablative lasers (2.56% ± 2.19% vs 7.48% ± 3.29%). This systematic review suggests ablative laser use for skin resurfacing is a safe and effective modality to treat a range of pathologies from photodamage and acne scars to hidradenitis suppurativa and posttraumatic scarring from basal cell carcinoma excision. Further studies are needed, but these results suggest that ablative lasers are a superior, safe, and effective modality to treat damaged skin.  相似文献   

12.
ABSTRACT:  Two new collagen-based lidocaine-containing dermal fillers, ArteSense™/ArteFill™ (Artes Medical, San Diego, CA) and Evolence® (Colbar LifeScience Ltd., Herzliya, Israel), have proved to be of particular interest to men, many of whom seek a long-lasting or permanent correction. ArteFill™ has been available in the United States since 2006, and it is expected that Evolence® will reach the American market in 2008. The properties of the two products will be described, and experience based on the administration of many hundreds of syringes of both products by a Canadian dermatologist will be detailed here, with tips and precautions to optimize patient outcomes.  相似文献   

13.
14.
12 cases of occupational allergic contact dermatitis caused by decorative plants were diagnosed in a 14-year period. The patients were middle-aged, and their average exposure time was 13 years. The plant families and plants causing occupational contact dermatitis were Compositae (5 patients: chrysanthemum, elecampane, gerbera, feverfew), Alstroemeriaceae (5 patients, Alstroemeria ), Liliaceae (4 patients; tulip, hyacinth). Amaryllidaceae (2 patients: narcissus) and Caryophyllaceae (2 patients; carnation, cauzeflower). The known chemical allergens causing dermatitis were tuliposide-A and sesquiterepene lactones, such as alantolactones and parthenolide, in the Liliaceae and Compositae families. 7 of the 12 patients were able to continue their work; 5 were not because of severe relapses of skin symptoms. The plant allergen and extract series currently available are of great help in the diagnosis.  相似文献   

15.
Studies integrating clinicopathological and genetic features have revealed distinct patterns of genomic aberrations in Melanoma. Distributions of BRAF or NRAS mutations and gains of several oncogenes differ among melanoma subgroups, while 9p21 deletions are found in all melanoma subtypes. In the study, status of genes involved in cell cycle progression and apoptosis was evaluated in a panel of 17 frozen primary acral melanomas. NRAS mutations were found in 17% of the tumors. In contrast, BRAF mutations were not found. Gains of AURKA gene (20q13.3) were detected in 37.5% of samples, gains of CCND1 gene (11q13) or TERT gene (5p15.33) in 31.2% and gains of NRAS gene (1p13.2) in 25%. Alterations in 9p21 were identified in 69% of tumors. Gains of 11q13 and 20q13 were mutually exclusive, and 1p13.2 gain was associated with 5p15.33. Our findings showed that alterations in RAS‐related pathways are present in 87.5% of acral lentiginous melanomas.  相似文献   

16.
17.
18.
19.
20.
Background: Pemphigus vulgaris is a potentially life‐threatening autoimmune disorder of the skin and mucous membranes characterized by antibodies against epidermal adhesion molecules. Clinically characteristic are painful chronic blisters or erosions of mucous membranes and skin. There are no published studies on the impact o this disease on quality of life. Patients and methods: This registration was performed within the scope of the German BSD (Bullous Skin Disease) study group, from November 1997 until January 2002. A total of 36 patients with the first diagnosis of pemphigus vulgaris were registered at the university hospitals of Dresden, Erlangen, Kiel, Mannheim, München and Würzburg. Thirty of the 36 (83 %) patients participated in the quality of life questionnaire utilizing the German version of ‘Dermatology Life Quality Index’ (DLQI) provided by A. Y. Finlay. The DLQI varies from 0 to 30 with an increased DLQI score indicating a decrease in quality of quality. Results: The overall DLQI total score of 10 ± 6,7 in the investigated pemphigus patients was significantly increased in comparison to other skin diseases. Conclusions: These results suggest that the DLQI can be a very useful additional outcome criteria for clinical studies with pemphigus vulgaris and in the treatment of these patients.  相似文献   

设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号