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1.
性病     
941696 大连地区性病患者、性乱者和健康人沙眼衣原体、人型支原体和解脲支原体感染现状的调查/姜仁惠…//中华流行病学杂志。-1994,15(2).-87~89 1992年1~6月对大连地区部分性病患者、性乱者和健康人进行了沙眼衣原体(Ct),人型支原体(Mh)和解脲支原体(Uu)血清抗体检测。结果表明,性病患者三种抗体阳性率最高,健康人的Ct和Uu阳性率最低。Uu和Mh抗体阳性率在性别上无明显差异。而男、女患者的Ct抗体阳性率分别高于性乱者和健康人。三种人有支原体和衣原体的混合感染。此外,还对大连地区Ct、Mh和Uu的感染特点进行了初步分析,为性传播疾病防治工作提供了理论依据。表4参2  相似文献   

2.
目的:了解解脲支原体(Uu)及人型支原体(Mh)在非淋菌性宫颈管炎中的药敏实验的特点及临床意义。方法:选择本科疑诊为宫颈管炎的性病患者,采用南京市黎明生物制品经营部的解脲支原体(Uu)及人型支原体(Mh)培养加药敏的试剂盒,进行Uu及Mh培养加药敏试验的临床研究。结果:400例疑诊为宫颈管炎共检出Uu及Mh阳性患者182例,阳性率为45.5%;其中Uu培养阳性者104例,阳性率为57.14%,Mh培养阳性者78例,阳性率为42.86%,患者中有Uu及Mh混合感染35例,阳性率为19.23%。结论:药敏试验结果显示,其中对红霉素、乙酰螺旋霉素、白霉素、四环素耐药的浓度最高;对强力霉素、美满霉素、氧氟沙星、环丙沙星次之:对氯霉素、强力霉素、交沙霉素耐药的浓度最低。临床医生应引起重视,提示明确的诊断是正确治疗的前提,合理用药,才能有效减少抗生素耐药菌株的产生。  相似文献   

3.
男性泌尿生殖道衣原体及支原体感染分析   总被引:1,自引:0,他引:1  
目的了解男性尿道炎患者中沙眼衣原体(CT)、解脲脲原体(UU)和人型支原体(Mh)的感染情况,并分析UU和Mh对常用抗菌药物的敏感性。方法 280例男性尿道标本应用免疫层析法检测CT抗原,并用支原体液体培养法检测UU和Mh。结果 280例标本中三种病原体的总阳性率为35.71%,其中CT阳性率为3.57%,UU阳性率为27.86%,Mh的阳性率为4.29%;UU和Mh药敏试验的结果显示敏感率较高的抗菌药物有强力霉素(94.87%)、美满霉素(94.87%)、交沙霉素(89.74%)、克拉霉素(87.18%)、阿奇霉素(84.62%)和加替沙星(84.62%)。结论 CT,UU和Mh是男性尿道炎的常见病原体,其中UU的感染率最高,临床上应重视该类病原体的检测;UU和Mh治疗应参考药敏试验结果合理用药。强力霉素和美满霉素是经验用药的最佳选择。  相似文献   

4.
目的 了解SLE患者血清弓形体IgG抗体的阳性率。 方法 以酶联免疫吸附试验 (ELISA)检测 72例SLE患者血清标本 ,同时以 5 8例健康人血清为对照。结果 SLE患者血清抗弓形体IgG抗体阳性率为 15 .3 %,对照组为3 .45 %,两组比较差异有显著性 (P <0 .0 5 )。结论 SLE患者有继发弓形体病的高度危险。  相似文献   

5.
STD就诊者阴道加特纳菌及其它病原体感染研究   总被引:3,自引:0,他引:3  
目的:探讨女性STD就诊者阴道加特纳菌(GV)及其它病原菌的感染情况.方法:检测疑为STD患者标本890份(患者组)和健康人标本120份(对照组),用实时荧光PCR检测患者解脲脲原体(Uu)、淋病奈瑟菌(NG)、沙眼衣原体(Ct)和阴道加特纳菌(GV),同时用超高倍显微诊断系统在相差视野下镜检念珠菌(CD)和阴道毛滴虫(TV).结果:STD患者组GV的阳性率为32.14%在CD(40.11%)之后占第2位、对照组GV的阳性率为7.5%.结论:STD患者GV阳性率较高,对STD患者应注意GV的检测和治疗.  相似文献   

6.
作者从1979年开始采用淋球菌菌毛抗原的间接血凝试验(淋球菌抗体试验,GAT)来替代补体结合试验(GCFT)作检测淋球菌抗体的常规方法.菌毛抗原提纯的方法为Hermodson法并略加改进.GAT的最高血清浓度是1/20.滴度1/40即为阳性.为评价GAT法,研究了以下各组人群:作淋病检查的1376例患者(其中有386例为淋病);年龄15~65岁的1384名健康人;54例脑膜炎球菌感染者;30例呼吸道感染的儿童及254例患非奈瑟氏菌感染而具有关节炎症状的患者.调查表明:①GAT的非特异性阳性反应是很少见的;②曾患过  相似文献   

7.
本文对 1998年 7月至 1999年 7月越秀区拘留所 489名拘留人员同时进行淋病、梅毒、HIV的检测。淋病阳性率 2 9% (14 489) ,梅毒阳性率 11 6 % (5 7 489) ,HIV阳性率 0 2 % (1 489)。淋病、梅毒、HIV三者之间合并感染阳性率为 0 %。女性感染性病的总阳性率为 17% ,男性感染性病的总阳性率为 9 2 %。  相似文献   

8.
目的:明确支原体感染与类风湿关节炎发病的相关性。方法:选取2017年1~12月我院诊治的类风湿关节炎患者作为研究对象,采集尿道拭子(57例)、咽拭子(120例)、关节液(43例)、宫颈拭子(20例)标本,用PCR方法检测解脲脲原体(Uu)、关节炎支原体(Mar)、人型支原体(Mh)及发酵支原体(Mf)。结果:共收集患者120例,咽拭子Uu阳性率22.5%、Mh阳性率14.2%、Mar阳性率0.8%、Mf阳性率0.8%;尿道拭子Uu阳性率31.6%、Mh阳性率21.1%、Mar阳性率3.5%、Mf阳性率0.0%;关节液的Uu阳性率11.6%、Mh阳性率4.7%、Mar阳性率2.3%、Mf阳性率0.0%;宫颈拭子Uu阳性率45%、Mh阳性率10%、Mar阳性率5%、Mf阳性率0.0%。Uu阳性类风湿关节炎患者与阴性者比较,骨密度降低、关节疾病活动度评分(DAS)3.2~5.1、DAS>5.1有统计学差异(P<0.05)。结论:Uu与类风湿关节炎的严重程度可能具有相关性。  相似文献   

9.
目的:探讨生殖医学科门诊患者支原体感染状况及其药物敏感试验结果,为临床用药提供参考。方法:对2015年5月至2016年10月生殖医学科门诊患者送检的6826例支原体培养和药物敏感试验结果进行回顾性分析。结果:支原体感染阳性率为51.2%(3495/6826),解脲脲原体(Uu)、人型支原体(Mh)及Uu+Mh同时感染阳性率分别为49.66%、3.06%和1.52%;男性患者和女性患者Uu检出率分别为44.95%和63.8%;男性患者和女性患者Mh检出率则分别为1.6%和7.41%;12种抗菌药物的敏感率分别为交沙霉素(JOS)99.86%、强力霉素(DOX)99.45%、美满霉素(MIN)99.37%、四环素(TET)96.79%、克拉霉素(CLA)93.53%、罗红霉素(ROX)92.80%、阿奇霉素(AZI)91.93%、红霉素(ERY)88.7%、司巴沙星(SPA)24.88%、氧氟沙星(OFL)22.06%、左氧氟沙星(LEV)21.70%和环丙沙星(CIP)2.28%。结论:生殖医学门诊患者中支原体感染率较高,Uu为主要感染类型,女性感染率高于男性,大环内酯类抗生素(JOS、ERY、ROX、AZI)和四环素类抗生素(TET、DOX、MIN、CLA)为抗菌药物选择首选。  相似文献   

10.
目的:探讨前列腺及尿道分泌物中支原体检测和男性泌尿生殖系统感染的关系。方法:共收集在上海市浦东新区光明中医院泌尿科门诊就诊的男性共270例,通过检测其前列腺液和尿道分泌物中解脲支原体(Uu)和人型支原体(Mh)的感染率,以及泌尿生殖系统炎症的检出率,分析前列腺及尿道分泌物中支原体检测和男性泌尿生殖系统感染的关系。结果:所有研究对象中Uu检出58例,总检出阳性率21. 48%; Mh检出76例,总检出阳性率28. 15%;支原体(Un+Mh)检出98例,总检出阳性率36. 30%;泌尿生殖道炎症检出173例,总检出阳性率64. 07%;炎症组总Uu检出率、总Mh检出率、总Uu+Mh检出率均高于非炎症组,且差异有统计学意义(χ~2=4. 725,P=0. 029;χ~2=5. 859,P=0. 015;χ~2=15. 09,P=0. 0001);炎症组的尿道分泌物Uu检出率和Uu+Mh检出率高于非炎症组且差异有统计学意义(χ~2=6. 227,P=0. 013;χ~2=5. 461,P=0. 019)。炎症组的前列腺液Mh检出率和Uu+Mh检出率高于非炎症组,且差异有统计学意义(χ~2=5. 877,P=0. 015;χ~2=15. 09,P=0. 0001);在炎症组中慢性前列腺炎,非淋菌性尿道炎,睾丸/附睾炎三种疾病的Uu检出阳性率有统计学差异(χ~2=19. 614,P=0. 0001);三种疾病的Uu+Mh检出阳性率差异有统计学意义(χ~2=16. 802,P=0. 0001)。结论:在泌尿系统炎症的患者的前列腺及尿道分泌物支原体的检出阳性率较高。  相似文献   

11.
目的:了解深圳光明地区泌尿生殖系支原体感染特点及药敏特征。方法:对2011年1月至2012年12月来深圳光明地区两家医院4956例泌尿生殖系感染患者的标本进行支原体培养及药敏实验,统计支原体的检出率并对药敏结果进行分析。结果:支原体阳性2682例,阳性率54.1%,解脲支原体(UU)、人型支原体(Mh)及UU和Mh混合感染的阳性率分别是45.4%、0.7%和12.6%,药敏结果显示UU对强力霉素、米若环素最为敏感分别是95.7%和90.3%,其次是交沙霉素、克拉霉素、阿奇霉素;Mh对强力霉素、米若环素最为敏感,分别是93.8%和94.3%,其次是交沙霉素;Uu+Mh对强力霉素、米若环素最为敏感,分别是91.6%和94.4%。结论:深圳光明地区泌尿生殖系感染的主要以UU为主,其次是UU和Mh引起的混合感染,单独由Mh引起的感染较少,而且三者对抗生素的敏感性存在一定的差异,临床医师一定要根据药敏的结果选择恰当的抗生素,以减少耐药菌株的产生。  相似文献   

12.
Gonorrhea case reports to the Alaska Department of Health and Social Services were used to study the contribution of reinfection to rates of gonorrhea infection in Alaska. The case reports of 13,910 infections among 11,132 persons who had laboratory-proven gonorrhea between 1983 and 1987 were examined. Among 1,886 persons who had multiple infections, the average number of infections per person was 2.5 (range = 2-11). These persons accounted for 33.5% of all infections and 16.9% of all patients with gonorrhea from 1983 to 1987. Compared to persons with one infection, those having multiple infections were more likely to be Alaska Natives (relative risk = 1.8, 95% confidence interval = 1.6-1.9) and less than 21 years of age (relative risk = 1.3, 95% confidence interval = 1.2-1.4). There was no difference in risk between men and women. Two thirds of the reinfections occurred within 12 months of the initial infection. If gonorrhea incidence were calculated based on the number of people infected rather than as a "case rate," the mean annual rate (per 100,000) from 1983 to 1987 decreased from 1,644 to 1,228 (a 25.3% decrease) for Alaska Natives and from 316 to 267 (a 15.5% decrease) for non-Natives. Reporting gonorrhea incidence rates by number of persons infected rather than by total number of cases more accurately measures gonorrhea morbidity in a population and will allow prevention efforts to be directed to those persons who contribute the most to perpetuating the disease.  相似文献   

13.
We retrospectively analyzed the efficacy of ceftriaxone in a single dose of 125 mg given intramuscularly for treatment of uncomplicated gonorrhea. Neisseria gonorrhoeae was eradicated from 152 (99%) of 154 patients who returned for test-of-cure, including all 83 heterosexual men and women and 69 (97%) of 71 homosexual men. Cure was achieved for 109 (99%) of 110 urethral or cervical infections, 52 (98%) of 53 rectal infections, and 15 of 15 pharyngeal infections. All infected sites were cured in 58 additional patients treated with ceftriaxone (125 mg) plus tetracycline (500 mg four times daily for seven days). These results confirm those of earlier clinical trials showing that 125 mg of ceftriaxone is effective therapy for uncomplicated gonorrhea in a geographic area with a high prevalence of gonococci with chromosomally mediated antibiotic resistance.  相似文献   

14.
泌尿生殖道支原体的检测和药敏分析   总被引:21,自引:0,他引:21  
目的:了解沈阳地区2000-2002年泌尿生殖道分泌物中分离的解脲脲原体(Uu)和人型支原体(Mh)的药物敏感情况。方法:应用Mycoplasma IST试剂盒对Uu和Mh进行检测,并对6种抗菌药物的药敏试验进行分析。结果:6966例可疑泌尿生殖道感染患者中,2365例检出支原体,其中Uu 1589例,Mh 154例,Uu Mh 622例。3组检出的支原体对抗菌药物敏感性由高到低依次为Uu、Mu、Uu Mh。3组检出的支原体对多西环素、交沙霉素、原始霉素敏感性均很高,对氧氟沙星的敏感性较低。支原体对6种抗菌药物的敏感性逐年下降,出现对6种抗菌药物均耐药的支原体。结论:支原体对抗菌药物的耐药性逐年增加。支原体药敏试验可以指导合理用药,减少耐药株的产生。  相似文献   

15.
Ureaplasma urealyticum strains isolated from urethral specimens of 112 patients with nongonococcal urethritis, 17 with gonorrhea, and 33 asymptomatic carriers (controls) were tested by the growth-inhibition test with standard ureaplasma antisera (serotypes 1-8). Cases with more than one serotype (two to four types) were encountered in 36.6% of patients with nongonococcal urethritis, 29.4% of those with gonorrhea, and 21.2% of controls. The most frequently recovered serotypes were type 4 from patients with nongonococcal urethritis (57.1%) and type 2 from patients with gonorrhea and controls (35.2% and 36.3%, respectively). The difference in frequency of serotype 4 between patients with nongonococcal urethritis and controls was statistically significant (P less than .001). An additional serotyping with types 9 and 10 antisera of the nontypable strains from patients with nongonococcal urethritis and controls (17.8% and 21.2%, respectively) revealed three type-9 strains. The results show a need for utilization of serotyping of U. urealyticum in studies of the epidemiology and transmissibility of genital infections with U. urealyticum.  相似文献   

16.
OBJECTIVES: We hypothesized that an active follow-up program to assess for reinfection after gonorrhea treatment could be a useful disease control strategy. GOAL: We evaluated an active follow-up and repeat testing program for all Baltimore sexually transmitted disease clinic patients diagnosed with gonorrhea. STUDY DESIGN: From September 2003 to May 2004, all clients with a treated gonorrhea infection were advised to return 3 months later for repeat testing. If clients did not return as scheduled, field outreach was attempted. At follow-up visits, urine was tested for gonorrhea and consenting participants completed a behavioral survey. In addition, we reviewed morbidity records for any intercurrent gonorrhea infections reported during the project period. RESULTS: Of the 667 participants diagnosed with gonorrhea at baseline, 54 had a gonorrhea reinfection diagnosed for an incidence of 13.8 per 100 person-years. One hundred seventy-eight (27%) either presented for a follow-up visit or were located through field efforts, and of these, 5 (2.8%) had gonorrhea detected on follow-up urine testing. No measured factors had predictive value in identifying gonorrhea reinfection. CONCLUSIONS: Although reinfection rates were high, we found that field staff intervention to increase follow-up testing rates did not identify a significant amount of repeat infections compared with passive surveillance.  相似文献   

17.
BACKGROUND: Bacterial sexually transmitted diseases (STDs) among men who have sex with men (MSM) have recently increased in Seattle. GOALS: Serovar and auxotype typing of strains was used to assess the epidemiology of anorectal chlamydial and gonococcal infections among MSM attending an STD clinic. STUDY DESIGN: The prevalences of anorectal chlamydial infection and gonorrhea among MSM attending an STD clinic during the period of 1994 to 1996 were compared with prevalences during 1997 to 1999. A retrospective case-control study of MSM attending an STD clinic between 1997 and 1999 was performed. Anorectal chlamydial isolates were characterized by serovar and gonococcal isolates were characterized by serovar and auxotype. Infected MSM were mapped by residence and strain type. RESULTS: Prevalences of anorectal chlamydial and gonococcal infections increased from 4.0% and 6.3%, respectively, during 1994-1996 to 7.6% and 8.7%, respectively, during 1997-1999 (P = 0.004 and P = 0.013 for chlamydial infection and gonorrhea, respectively). Most chlamydial infections were caused by serovars G (47.9%) and D (29.6%), and most gonococcal infections were caused by auxotype/serovar classes Proto/IB-1 (43.3%), Proto/IB-3 (16.5%), and Proto/IB-2 (10.3%). MSM with anorectal chlamydial infection more often had chlamydial urethritis (P = 0.005) and were not white (P = 0.046), in comparison with controls. MSM with anorectal gonorrhea more often had pharyngeal gonorrhea (P < 0.001), had a history of gonorrhea (P = 0.003), and were younger than age 30 years (P = 0.039), in comparison with controls. Residences of MSM with anorectal gonorrhea were clustered in urban areas, whereas those of MSM with anorectal chlamydial infection were more dispersed. CONCLUSION: Prevalences of anorectal chlamydial infection and gonorrhea among MSM in Seattle have increased dramatically over the past 3 years. Serovar and auxotype analyses indicate these increases are not clonal but are due to the spread of unique distributions of strains that differ from those causing urogenital infections in the same community.  相似文献   

18.
In 1985, 2,455 cases of infection due to penicillinase-producing Neisseria gonorrhoeae were reported from Dade County, Florida. These cases represent the largest concentration of PPNG infections reported to date in the United States. A zip code-based geographic analysis of morbidity caused by gonorrhea and PPNG identified a core area where the percentage of all gonorrhea cases due to PPNG was 31-36%. This percentage decreased in a radial pattern outward from the central core. A prospective study of patients presenting to the Dade County central clinic with gonorrhea found that men infected with PPNG were more likely to have medicated themselves with illicit antibiotics than were patients infected with penicillin-sensitive N. gonorrhoeae (odds ratio, 3.6; 95% confidence interval, 1.9-6.8). Of all self-medicated patients, 42% obtained antibiotics via illicit over-the-counter purchase at pharmacies in the hyperendemic area. In contrast to previous reports, PPNG infection was not associated with either narcotic- or prostitution-related activities. The results show that PPNG is endemic in Dade County and is arrayed in a core distribution. Antibiotic abuse may have played an important role in the Miami epidemic and in the establishment of PPNG as an endemic strain.  相似文献   

19.
Although previous workers have emphasized that venereal disease is rife in many developing countries, there are no reliable statistics on the relative incidence of such infections. This dearth of information about these infections in Africa is directly related to economic factors and the lack of modern diagnostic facilities and medical manpower. The pattern of these diseases was studied over a 30-month period at a hosptial clinic serving an African population of about 2 million people. Standard diagnostic methods were used. The age distribution of patients conformed with that in other parts of the world except that more prepubertal patients were seen. The male-to-female ratio was 3:1. Nonspecific genital infections were the most common (25.9%) followed closely by postpubertal gonorrhea (19.5%). Prepubertal gonorrhea was more common than reported elsewhere (4.0%) and this may be because the children have been in contact with infected clothing of their parents or family members. Most strains of Neisseria gonorrhea were sensitive to penicillin by the disc method, but a few were markedly resistant to this and other agents. It is to be expected that the problem of gonococcal drug resistance will increase unless effective legislation is introduced to discourage self-medication with antimicrobial preparations. Venereophobia was common (6.6%) and sociocultural factors may play a dominant role in the incidence of the basicially psychiatric condition. Syphilis constituted 2.5% of diagnoses and this can be regarded as an ominous sign in an area where yaws was endemic 2 decades ago and is now virtually nonexistent. It is essential to provide facilities for diagnosis and treatment in every major African town in order to control such infections.  相似文献   

20.
BACKGROUND: Providers not skilled in the evaluation of sexually transmitted infections (STIs) may treat pubic lice infestation without considering other organisms. This study compared the rate of chlamydia and gonorrhea infections in adolescents with and without pubic lice. GOAL: The goals of the study were to compare the rate of chlamydia and gonorrhea infections between adolescents infested or not infested with pubic lice and to evaluate lice infestation as a predictor for concurrent chlamydia or gonorrhea infection. STUDY DESIGN: A retrospective chart review of sexually active adolescents at a juvenile detention center in the Midwest between July 1998 and June 2000 was conducted. The index group was 62 adolescents with pubic lice screened for concurrent STIs. The control group included 201 randomly selected adolescents without pubic lice who underwent STI screening. RESULTS: In the entire study population (263 subjects), there were 60 cases of chlamydia (23% of all subjects) and 29 cases of gonorrhea (11%). Neisseria gonorrhoeae infection was present in 18% of index subjects and 9% of controls. Chlamydia trachomatis infection was noted in 39% of index subjects and 18% of controls. Pubic lice infestation predicted C trachomatis infection (odds ratio = 3.31). CONCLUSIONS: Pubic lice infestation is predictive of a concurrent C trachomatis infection in this population. Adolescents infested with pubic lice should be screened for other STIs, including chlamydia and gonorrhea.  相似文献   

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