居家军队离退休干部阿尔茨海默病患者营养不足的影响因素

目的:调查居家军队离退休干部阿尔茨海默病患者中营养不足现状并分析其影响因素。方法:采用一般资料调查表、简易营养评价精法量表对83例居家的军队离退休干部阿尔茨海默病患者营养状况进行调查,并与166例健康老年人进行比较,分析导致营养不足的危险因素。结果:阿尔茨海默病患者营养不足的发生率为46.52%,显著高于对照组的10.84%(χ~2=43.201,P0.001);年龄≥75岁、中重度痴呆、病程≥3年、伴有吞咽障碍症状是导致营养不足的危险因素。与营养正常的AD患者相比,营养不足的AD患者中年龄≥75岁(χ~2=11.487,P0.001)、中重度痴呆(χ~2=7.547,P0.01)、病程≥3年(χ~2=4.155,P0.05)、伴有吞咽障碍症状(χ~2=8.763,P0.01)的比例显著升高。Logistic回归分析显示,年龄≥75岁(β=0.826,Waldχ~2=7.322,P0.001)、中重度痴呆(β=0.713,Waldχ~2=4.310,P0.05)、有吞咽障碍症状(β=0.772,Waldχ~2=5.306,P0.01)与营养不足有关联。结论:居家军队离退休干部阿尔茨海默病患者的营养不足发生率高,应加强对其发生危险因素的识别。     

珠江三角洲创伤事故后应激障碍的发生及影响因素分析

目的了解珠江三角洲地区创伤事故后住院患者应激障碍(PTSD)症状的发生情况并分析影响因素。方法于2009年4月-2010年2月抽取珠江三角洲地区6个城市7所医院住院创伤患者,采用自编问卷和创伤后应激障碍症状自评量表(PCL-C量表),调查PTSD症状发生率并分析影响因素。结果①554例有效样本PCL-C评分均值为(31.94±11.68),PTSD症状筛查阳性率为28.5%(PCL-C分值≥38分),其中重度为7.8%(分值≥50分);②影响因素分析显示,女性(χ2=15.937,P<0.001)、受教育程度低(χ2=9.597,P<0.05)、多部位伤(χ2=8.093,P<0.01)、预期生活自理程度差(χ2=15.757,P<0.001)、预期无工作能力(χ2=19.036,P<0.001)的患者PTSD症状发生率较高;③社会支持方面,缺乏友情精神支持的患者PTSD的发生率较有大量友情支持的患者高(χ2=13.307,P<0.05)。结论珠江三角洲地区创伤事故后PTSD症状发生率较高,性别、受教育程度、创伤严重程度、对未来生活的不良预期及缺乏社会友情支持是主要的影响因素。     

前列腺患者心理痛苦现状及其危险因素

目的:探讨前列腺患者心理痛苦现状及其危险因素。方法:选取本院2016年8月至2019年8月收治的146例前列腺疾病患者,使用心理痛苦温度计(DT)进行问卷调查评估患者心理痛苦。比较前列腺癌与前列腺炎患者的心理痛苦发生率与严重程度。采用多元线性回归分析前列腺疾病患者心理痛苦的危险因素。结果:146例患者中心理痛苦发生率89.73%(131/146)。前列腺癌患者与前列腺炎患者心理痛苦发生率(χ~2=0.771,P=0.380)与严重程度(Z=4.498,P=0.212)的差异无统计学意义(P0.05)。不同年龄(χ~2=7.587,P=0.006)、收入(χ~2=8.603,P=0.000)、文化程度(χ~2=5.292,P=0.021)、婚姻状况(χ~2=5.450,P=0.020)、病程(χ~2=5.724,P=0.017)患者的DT评分的差异有统计学意义(P0.05)。多元线性回归性分析结果表示,年龄、婚姻状况、收入、病程、文化程度是患者心理痛苦的危险因素(OR=1.658,0.224,2.311,0.352,1.875;P0.05)。结论:DT可有效评估前列腺疾病患者心理痛苦程度,基于DT评估基础的前列腺疾病患者心理痛苦的危险因素包括年龄、文化程度、婚姻状况、月收入与病程。     

住院高血压患者焦虑抑郁共病的影响因素

目的:探讨住院高血压患者焦虑抑郁共病的影响因素。方法:以我院2015年4月-2017年10月住院治疗的389例高血压患者作为研究对象,采用医院焦虑抑郁量表对患者的焦虑、抑郁情况进行评估,并根据焦虑抑郁的发生情况分为单纯焦虑抑郁组和焦虑抑郁共病组,对分组后患者的临床资料进行比较,并对影响焦虑抑郁共病的危险因素进行多因素Logistic回归分析。结果:389例患者中共检出焦虑抑郁患者262例,发病率为67.35%,其中单纯焦虑患者73例(27.86%),单纯抑郁患者104例(36.69%),焦虑抑郁共病患者85例(32.44%)。根据评估结果单纯焦虑/抑郁组患者177例,焦虑抑郁共病组患者85例,组间比较焦虑抑郁共病组患者女性(χ~2=8.608,P=0.003)、病程≥5年(χ~2=4.445,P=0.035)、高血压2~3级(χ~2=5.654,P=0.017)以及多次住院(χ~2=4.602,P=0.032)患者相比单纯焦虑/抑郁组患者明显增加;经Logistic回归分析,女性(OR=2.119,P=0.034)、病程≥5年(OR=2.008,P=0.032)、高血压分级2~3级(OR=2.122,P=0.004)以及多次住院(OR=1.963,P=0.005)均为影响焦虑抑郁共病的独立危险因素。结论:女性、病程较长、高血压分级较高以及多次住院的高血压患者是焦虑抑郁共病的高危人群。     

住院精神分裂症患者高血糖发生率及其相关因素

目的:对住院精神分裂症患者高血糖发生率及其相关因素进行调查.方法:采用 自制的调查表对287例住院精神分裂症患者进行了调查,分别收集了患者的性别、年龄、受教育年限、病程、精神疾病家族史、既往病史(高血压、高脂血症)、服用抗精神病药物等相关资料,同时测了体质量、身高、血糖、甘油三酯、总胆固醇、高密度脂蛋白及低密度脂蛋白等相关指标.结果:287例住院精神分裂症患者中,存有高血糖65例,发生率为22.6％.住院精神分裂症患者中,高血糖组年龄明显大于非高血糖组(t=-2.310,P＜0.05);高血糖组甘油三酯明显高于非高血糖组(t=-2.512,P＜0.05);高血糖组高密度脂蛋白明显低于非高血糖组(t=2.687,P＜0.01).≥50岁的住院精神分裂症患者伴有高血糖比率明显高于＜50岁的患者(x2=6.609,P＜0.05);≥50岁的住院精神分裂症患者空腹血糖明显高于＜50岁的患者(t=-2.978,P＜0.01).Logistic回归分析显示,年龄、家族史、甘油三酯与高血糖的发生有关(P＜0.05).结论:住院精神分裂症患者高血糖发生率较高,年龄越大、有精神疾病家族史、甘油三酯值越高的患者,发生高血糖的风险越大.     

CT评分与急性胰腺炎伴心包积液的相关性研究

目的 研究急性胰腺炎（AP）向纵隔扩散致心包腔积液的多排螺旋CT表现及其与急性胰腺炎CT指数（CTSI）、休克、死亡率的相关性。方法 回顾性分析2017年7月~2018年6月我院收治的274例AP患者,入院行CT,观察患者心包积液发生率,测量其厚度;用CTSI分级评估AP严重程度并分析心包积液与CTSI、休克率及死亡率之间的关系。结果 CTSI评分轻、中、重度AP患者分别占43.07%、53.28%、3.65%;胰周积液向纵隔扩散时54例（19.71%）食管裂孔受累,10例（3.65%）主动脉裂孔受累,6例（2.19%）下腔静脉裂孔受累;34例（12.41%）患者并发心包积液,心包积液厚度与CTSI正相关（r=0.40,P＜0.05）;患者休克发生率、死亡率分别为16.42%、1.46%;AP并心包积液患者休克发生率、死亡发生率均高于无心包积液患者,差异有统计学意义（P＜0.05）。结论 AP伴心包积液发生率较低,胰周积液可经膈肌裂孔向纵隔扩散。心包积液可做为评价AP严重程度的辅助指标。     

血浆NT-proBNP对冠心病患者抑郁的影响

目的:探索血浆中N末端B型利钠肽原(NT-proBNP)水平对冠心病患者抑郁的影响。方法:选取2014年12月-2017年3月于我院接受治疗的97例冠心病患者为研究对象,按照汉密尔顿抑郁量表(HAMD)评分将患者分为两组,54例抑郁评分总分≥14分的患者为抑郁组,43例抑郁评分总分14分的患者为非抑郁组。对比两组患者血浆NT-proBNP水平,统计患者既往病史、用药等情况。结果:抑郁组患者年龄为(62.52±12.16)岁,大于非抑郁组患者年龄(54.19±10.34)岁(t=3.578,P0.001);抑郁组患者在职10例(18.51%),少于非抑郁组患者在职21例(48.83%)(χ~2=5.789,P=0.016);抑郁组BMI显著高于非抑郁组患者(t=10.696,P=0.000);抑郁组NT-proBNP显著高于非抑郁组(t=70.755,P=0.000);Logistic回归显示,血清NT-proBNP高水平是造成冠心病患者抑郁的独立危险因素(OR=1.442,P=0.004)。结论:血浆NT-proBNP水平是造成冠心病患者抑郁的独立危险因素,可以作为冠心病患者抑郁的临床早期检测指标。     

冠状动脉旁路移植术后患者情绪障碍发生特征及影响因素

目的:探讨冠状动脉旁路移植术后患者情绪障碍发生特征及影响因素。方法:选取2018年1月1日-6月30日在我院行冠状动脉旁路移植术的200例冠心病患者作为研究对象,以有、无情绪障碍将其分为研究组114例和对照组86例,采用汉密尔顿抑郁量表(Hamilton Depression Scale,HAMD)对两组焦虑、抑郁症状情况进行调查,并采用单因素分析以及Logistic逐步回归分析患者冠状动脉旁路移植术后患者情绪障碍发生影响因素,并对调查结果进行分析。结果:冠状动脉旁路移植术后情绪障碍发生率为57.00%,抑郁症状得分为(18.14±3.56)分;单因素分析结果显示:性别、医疗费用支付方式、既往合并抑郁病史等因素与冠状动脉旁路移植术后情绪障碍相关(χ~2=13.142,P0.001;χ~2=3.949,P=0.047;χ~2=5.235,P=0.022);Logistic逐步回归分析结果显示:女性、既往抑郁病史为冠心病患者经冠状动脉旁路移植术后情绪障碍发生的独立预测因素[Or=2.14(1.33～3.44),Or=2.18(1.33～3.56)]。结论:冠状动脉旁路移植术后患者焦虑、抑郁症状发生率较高。     

骨盆骨折合并尿路损伤患者心理应激状态及影响因素

目的:调查骨盆骨折合并尿路损伤患者心理应激状态,总结其相关影响因素。方法:采用问卷调查法对2014年2月-2016年3月医院收治的76例男性骨盆骨折合并尿路损伤患者,均采用一般资料调查问卷、症状自评表(SCL-90)、国际勃起功能评分表(IIEF-5)调查患者基线资料、心理应激状态及勃起功能,分析影响骨盆骨折合并尿路损伤心理状态的相关因素。结果:本组心理障碍检出率为68.42%,存在心理障碍患者在年龄(χ~2=7.639,P0.05)、家庭年收入(χ~2=5.068,P0.05)、手术方式(χ~2=4.251,P0.05)、尿道分离长度(χ~2=12.612,P0.05)、前列腺移位(χ2=12.612,P0.05)、耻骨联合分离(χ~2=5.196,P0.05)、骨盆骨折类型方面(χ~2=4.737,P0.05)与非心理障碍患者存在差异(P0.05);本组勃起功能障碍发生率为59.21%;存在勃起功能障碍患者在年龄(χ2=4.093,P0.05)、手术方式(χ~2=6.741,P0.05)、尿道分离长度(χ~2=17.891,P0.05)、前列腺位移(χ2=3.922,P0.05)、耻骨联合分离(χ~2=6.555,P0.05)方面与非勃起功能障碍者存在差异;多元Logistic回归分析显示,年龄≤30岁(OR=1.421)、家庭年收入3万元(OR=1.269)、行尿道端吻合术(OR=1.987)、尿道分离长度≥3.5cm(OR=2.065)、耻骨联合分离(OR=1.588)、前列腺横向移位(OR=1.369)均为骨盆骨折合并尿路损伤患者发生心理障碍的危险因素(P0.05);骨盆骨折合并尿路损伤患者SCL-90评分与IIEF-5评分呈显著正相关(r=0.461,P0.05)。结论:骨盆骨折合并尿路损伤患者心理障碍发生率较高,且与勃起功能障碍发生率呈正相关,年龄、家庭年收入、手术方式、尿道分离长度、耻骨联合分离、前列腺移位均为患者心理障碍发生的影响因素。     

D-二聚体、白蛋白、CT严重程度、血细胞计数、非高密度脂蛋白等在急性胰腺炎临床诊断及病情评估中的作用

目的 探讨D-二聚体(D-D)、白蛋白(Alb)、计算机断层扫描(CT)严重程度、血细胞计数、非高密度脂蛋白(NHDL)等在急性胰腺炎(AP)临床诊断及病情评估中的作用。方法 选取2020年1月至2022年12月在本院收治的AP患者127例作为AP组，根据病情严重程度将其分为轻症AP组(MAP组，n=56)、中度AP组(MSAP组，n=31)和重症AP组(SAP组，n=40),另同期随机选取在本院行健康体检者127例作为对照组，比较各组D-D、Alb、CT严重程度[CT严重指数(CTSI)]、血常规[白细胞(WBC)、血小板(PLT)]计数和NHDL水平，采用受试者工作特征曲线(ROC)评价上述指标对AP的诊断价值；比较不同严重程度患者的Ranson评分，采用Pearson分析指标与评分的相关性。结果 AP组D-D、WBC、NHDL水平和CTSI评分均高于对照组，Alb、PLT水平均低于对照组(P<0.05)。ROC结果显示，D-D、WBC、NHDL、Alb、PLT和CTSI评分及其联合检测诊断AP的曲线下面积(AUC)分别为0.749、0.738、0.737、0.735、0.7...     

日资企业员工心理健康状况影响因素分析

目的了解日资企业员工的心理健康状况和影响因素。方法采用分层整群抽样的方法在广州市经济技术开发区某日资企业随机抽取450名员工,采用症状自评量表(SCL-90)和基本信息调查表对员工进行心理健康状况调查,采用单因素卡方分析和多因素非条件Log istic回归统计方法分析日资企业员工的心理健康影响因素。结果心理问题阳性率为38.1%。经单因素卡方分析,不同性别、年龄、文化程度、婚姻、月收入员工心理问题阳性率不同(χ2=10.903,P=0.001)、(χ2=9.561,P=0.043)、(χ2=7.607,P=0.020)、(χ2=5.528,P=0.019),(χ2=8.372,P=0.015)。多因素非条件Log istic回归分析,女性员工心理问题阳性率较高(OR=2.257,P<0.05),而文化程度越低,心理问题的阳性率越高(OR=0.713,P<0.05)。结论日资企业员工心理问题阳性率较高,需要高度重视员工的心理健康。女性、学历低是日资企业员工心理问题的重要影响因素。     

颅脑外伤后并发低钠血症的危险因素分析

目的探讨颅脑外伤患者并发低钠血症的发生机制及危险因素,以期为其早期预测及预防提供参考。方法回顾性分析2016年6月至2019年6月我院收治的185例中型和重型颅脑外伤患者的临床资料,包括导致低钠血症的不同病因、损伤类型、性别、格拉斯哥昏迷(GCS)评分、手术、脑水肿、颅底骨折和穿透性性损伤等;采用单因素χ^2检验和多因素Logistic回归分析探究颅脑外伤后并发低钠血症的危险因素。结果所有患者中,80例出现低钠血症,其中钠盐摄入不足、利尿剂过量使用47例,抗利尿激素分泌失调综合征19例,脑性耗盐综合征14例。低钠血症更多发生在脑挫裂伤、蛛网膜下腔出血和弥漫性轴索损伤患者中,差异具有统计学意义(P<0.05)。单因素χ^2检验结果显示,GCS评分(P=0.000)、脑水肿(P=0.000)、颅底骨折(P=0.000)、穿透性损伤(P=0.001)是颅脑外伤后并发低钠血症的相关因素。多因素Logistic回归分析结果显示,GCS评分(P=0.006)、脑水肿(P=0.006)、颅底骨折(P=0.000)、穿透性损伤(P=0.015)是颅脑外伤后并发低钠血症的危险因素。结论脑挫裂伤、蛛网膜下腔出血、弥漫性轴索损伤、GCS评分≤8分、脑水肿、颅底骨折和穿透性损伤的颅脑外伤患者更易发生低钠血症,应早期关注患者血清钠水平,明确病因及时纠正,防止病情恶化。     

Incidence,Risk Factors,Outcomes, and Risk Score Model of Acute Pancreatitis after Allogeneic Hematopoietic Stem Cell Transplantation

Acute pancreatitis (AP) has been recognized as an uncommon yet potentially lethal complication after hematopoietic stem cell transplant (HSCT). This retrospective, nested, case-control study reviewed data from 5284 consecutive patients who underwent allogeneic (allo)-HSCT between 2009 and 2018 at a single center, identifying 40 patients (0.76%) with AP after allo-HSCT. The diagnosis and severity of AP were established and classified according to existing criteria. Younger age (P = .008), grades II to IV acute graft-versus-host disease (P = .010), a history of donor lymphocyte infusion (P = .033), and pre-existing gallstones (P = .003) were independent risk factors of AP after allo-HSCT. Post-transplant AP had a trend to negatively influence overall survival (OS) and nonrelapse mortality (NRM) (P = .063) for allo-HSCT recipients, but no significant difference was found. Patients with moderately severe and severe AP had significantly lower OS (P = .002) and higher NRM (P = .000) than other patients. Based on these findings, a risk score model was also established to predict the occurrence of AP. Our risk score model performed well in terms of discrimination when applied to derivation samples. Patients were classified into a low-risk group (0 to 1 point), a medium-risk group (2 to 3 points), and a high-risk group (4 points or more). Significant difference was observed in AP incidence among the 3 groups. The predictive tool explored by our study might contribute to target high-risk patients and guide personalized AP prevention in allo-HSCT recipients.     

急性脑梗死患者并发胰岛素抵抗的研究

目的:探讨脑梗死急性期患者是否存在胰岛素抵抗(IR);在急性期血糖升高,是否使用胰岛素治疗.方法:本文测定了50例脑梗死患者和30例健康人的空腹血糖(FPG)、空腹血清胰岛素(FINS)、皮质醇(F),计算胰岛素敏感性指数(ISI),并与神经功能缺损评分和病灶大小进行直接相关分析.结果:脑梗死急性期患者FPG、FINS及F显著高于对照组(P＜0.001),ISI较对照组明显降低(P＜0.001).脑梗死轻型组和中重型组的FPG、F、ISI之间也存在明显差异(P＜0.001、P＜0.01、P＜0.05).ISI与脑梗死的面积呈负相关(r=-0.313,P＜0.05).ISI与神经功能缺损评分也呈负相关(r=-0.317,P＜0.05).中重型组的死亡率与病残率高于轻型组.结论:脑梗死患者急性期存在IR,且急性期胰岛素水平及IR程度与患者病情与预后有关.故在脑梗死急性期对血糖升高的患者应考虑使用胰岛素治疗.     

New-Onset Post-Transplant Diabetes Mellitus after Allogeneic Hematopoietic Cell Transplant Is Initiated by Insulin Resistance,Not Immunosuppressive Medications

New-onset post-transplant diabetes mellitus (PTDM) occurs frequently after allogeneic hematopoietic cell transplant (HCT). Although calcineurin inhibitors and corticosteroids are assumed to be the cause for hyperglycemia, patients developing PTDM have elevated fasting C-peptide levels before HCT and before immunosuppressive medications. To determine if PTDM results from established insulin resistance present before transplant, we performed oral glucose tolerance tests (OGTTs) and measured whole body, peripheral, and hepatic insulin sensitivity with euglycemic hyperinsulinemic clamps before and 90 days after HLA-identical sibling donor HCT in 20 patients without pretransplant diabetes. HCT recipients were prospectively followed for the development of new-onset PTDM defined as a weekly fasting blood glucose ≥ 126 mg/dL or random blood glucose ≥ 200 mg/dL. During the first 100 days all patients received calcineurin inhibitors, and 11 individuals (55%) were prospectively diagnosed with new-onset PTDM. PTDM diagnosis preceded corticosteroid treatment. During the pretransplant OGTT, elevated fasting (87 mg/dL versus 101 mg/dL; P = .005) but not 2-hour postprandial glucose levels predicted PTDM diagnosis (P = .648). In response to insulin infusion during the euglycemic hyperinsulinemic clamp, patients developing PTDM had lower whole body glucose utilization (P = .047) and decreased peripheral/skeletal muscle uptake (P = .031) before and after transplant, respectively, when compared with non-PTDM patients. Hepatic insulin sensitivity did not differ. Survival was decreased in PTDM patients (2-year estimate, 55% versus 100%; P = .039). Insulin resistance before HCT is a risk factor for PTDM independent of immunosuppression. Fasting pretransplant glucose levels identified PTDM susceptibility, and peripheral insulin resistance could be targeted for prevention and treatment of PTDM after HCT.     

不同亚型急性脑梗死出血转化的发生及相关危险因素分析

目的　研究不同亚型急性脑梗死出血转化的发生率及相关危险因素。 方法　选择南方医科大学南方医院及中山市人民医院神经内科自2008年1月至2011年12月收治的连续入院的急性脑梗死患者977例,按是否发生出血转化分为出血转化组（HT）142例及非出血转化组（NHT）835例,登记所有患者的基线资料并统计各病例的TOAST分型,分析不同亚型的急性脑梗死患者出血转化的发生率,采用Logistic回归分析脑出血转化的危险因素。 结果　大动脉粥样硬化性、心源性脑梗死、小动脉闭塞型脑梗死出血转化的发生率分别为12.8%、31.1%、6.6%;多因素Logistic回归分析显示出血转化的主要危险因素分别为大面积脑梗死（OR=10.498,95% CI6.520～17.131,P=0.000）、心房纤颤（OR=1.718,95% CI 　1.217～2.941,P=0.005）、糖尿病（OR=1.817,95%CI 1.135～2.903,P=0.012）及抗凝（OR=7.748,95% CI 　2.416～25.847,P=0.000）治疗。高血压、高低密度脂蛋白胆固醇以及抗血小板聚集治疗不是HT的独立危险因素。 结论　不同亚型脑梗死HT发生率不同,心源性脑梗死是脑出血转化的主要原因,大面积脑梗死、心房纤颤、糖尿病及抗凝治疗是HT的独立危险因素。     

Joint effect of alcohol and usual sleep duration on the risk of dysglycemia

STUDY OBJECTIVES: Sleep duration and alcohol use influence metabolic function. However, limited information exists regarding a combined effect of alcohol and sleep duration on glucose metabolism. The aim of this study was to assess the potential interaction effect of alcohol and inappropriate sleep duration on dysglycemia epidemiologically. DESIGN: Cross-sectional and observational retrospective study. SETTING: A medical health checkup program in a general hospital. PARTICIPANTS: 2933 apparently healthy Japanese individuals, aged 46 to 60 years. INTERVENTION: N/A. MEASUREMENTS AND RESULTS: We examined the relationships between usual sleep duration and dysglycemia, and furthermore assessed the combined effects of alcohol consumption and sleep time on glucose dysmetabolism. A U-shaped relationship between sleep duration and the prevalence of hyperglycemia (fasting plasma glucose level > or =110 mg/dL) was observed when sleep duration was treated as a continuous variables and centered at 7.0 h (quadratic term P = 0.024). In a multivariate quadratic regression model, there was a significant interaction effect between sleep duration and alcohol consumption category (nondrinkers, light-moderate drinkers [ethanol comsumption < or =210 g/wk], and heavy drinkers [ethanol consumption of >210 g/wk]) on fasting plasma glucose levels, with shorter or longer sleep duration being more diabetogenic in individuals who consumed more alcohol (P interaction = 0.018). Furthermore, we found a similar interaction effect of sleep duration and alcohol consumption on the incidence of hyperglycemia during the past 5 years (P interaction = 0.039). CONCLUSION: Alcohol interacts with reduced sleep duration to increase the risk of dysglycemia.     

Estimated risk of cardiovascular disease among the HIV-positive patients aged 40 years or older in Taiwan

BackgroundCardiovascular disease (CVD) is an emerging cause of morbidity and mortality among HIV-positive patients receiving successful combination antiretroviral therapy, but their CVD risk has been rarely investigated in Asia–Pacific region. We aimed to assess the CVD risk of HIV-positive Taiwanese outpatients.MethodsWe did cross-sectional questionnaire interviews to collect information of HIV-positive Taiwanese patients aged 40–79 at the HIV clinics of a medical center from 1 March to 31 August, 2017. The Framingham Risk Score (FRS), Atherosclerotic Cardiovascular Disease (ASCVD) risk score and Data-Collection on Adverse effects of Anti-HIV Drugs (D:A:D) risk score were used to estimate their CVD risk.ResultsOf the screened 1251 patients, 1006 (80.4%) with complete data to assess their CVD risk were included for analyses. The prevalence of patients aged 40–75 and with a high CVD risk was 30.6% by FRS, 3.7% by D:A:D (R) risk score, and 22.2% by ASCVD risk score. In multiple logistic regression, older age, current smoking, higher systolic blood pressure, and higher triglyceride and fasting glucose levels were independently associated with the ASCVD risk score ≥7.5%. If current smokers aged 55–59 had stopped smoking, the proportions of them with a 10-year CVD risk of ≥10% by FRS and ≥7.5% by ASCVD risk score would have decreased by 35.3% and 20.0%, respectively.ConclusionsHigher CVD risk estimates among HIV-positive Taiwanese aged 40–75 were associated with an older age, current smoking, higher systolic blood pressure, hypertriglyceridemia, and hyperglycemia. Smoking cessation could potentially lead to significant decreases of CVD risk.