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1.
目的了解缓解期精神分裂症患者的生活质量及其社会支持等因素对缓解期精神分裂症患者生活质量的影响。方法采用生活质量综合评定问卷(GQOL-74)对50例缓解期精神分裂症综合评定并与50名正常人进行对照,对缓解期精神分裂症患者同时施测社会支持评定量表(SSAS)、阳性与阴性症状量表(PANSS)和药物不良反应量表(TESS)。结果①生活质量总分和社会功能维度分研究组显著低于对照组;②社会支持与生活质量总分及躯体功能、心理功能和社会功能维度存在显著正相关;⑧药物副反应与生活质量总分及躯体功能和心理功能雄度存在显著负相关;④阳性症状与生活质量总分及心理功能维度存在显著负相关,阴性症状与生活质量总分及物质生活、躯体功能、心理功能和社会功能维度均存在显著负相关。结论缓解期精神分裂症患者的生活质量低于正常对照组,并且与社会支持、药物副反应和精神症状密切相关。  相似文献   

2.
首发精神分裂症患者生活质量对照研究   总被引:2,自引:0,他引:2  
目的 探讨首发精神分裂症患者生活质量及其与精神症状的关系。方法 采用生活质量综合评定问卷 ( GQOL1 -74)评定生活质量 ,比较首发精神分裂症患者治疗前后、首发与非首发精神分裂症患者生活质量的差异。用 PANSS量表评定精神症状 ,并与生活质量做相关分析。结果  1首发精神分裂症患者治疗前生活质量心理功能维度、社会功能维度、物质生活状态维度、总维度分均明显高于非首发精神分裂症患者 ;治疗后躯体功能维度、心理功能维度、社会功能维度、总维度分均高于非首发精神分裂症患者。2首发精神分裂症患者治疗 6个月后躯体功能维度、心理功能维度、社会功能维度、总维度分均显著高于治疗前。3精神症状与生活质量多项因子分及维度分有相关关系。结论 首发精神分裂症患者治疗前后生活质量均明显高于非首发精神分裂症患者 ,生活质量与精神症状严重程度有关。  相似文献   

3.
海洛因依赖者生活质量的比较研究   总被引:8,自引:0,他引:8  
目的:了解海洛因依赖病人生活质量。方法:应用生活质量综合评定问卷(gQOLI)对210例海洛因依赖病人(100例强制戒毒病人,110例自愿戒毒病人)与100例正常健康人进行对照研究。结果:海洛因依赖病人的躯体功能、心理功能、社会功能、物质生活条件均显著低于正常人。强制戒毒病人与自愿戒毒病人的生活质量没有显著差异。结论:海洛因依赖病人生活质量明显差于健康对照组,戒毒方式不是影响病人生活质量的主要因素。  相似文献   

4.
农村社区精神病患者的生活质量及其影响因素   总被引:11,自引:1,他引:10  
本文使用英国Oliver编制的生活质量概况表对四川省新津县农村社区129名精神分裂症、48名情感性精神障碍和104名健康人进行生活质量对照研究。发现精神病患者生活质量比健康人差,精神分裂症患者生活质量明显低于情感性精神障碍患者。在精神分裂症患者各生活领域中,居住条件,经济状况较差。精神症状明显的精神分裂症患者生活质量显著低于精神症状轻的患者。社会支持好的精神病患者生活质量较好,社会支持程度对精神分裂症患者生活质量的影响更显著。提示精神分裂症患者生活贫困,是社区服务的重点,应给予更多的关心和支持。  相似文献   

5.
社区精神分裂症病人照料者的生活质量研究   总被引:28,自引:2,他引:26  
通过对93名精神分裂症患者的家庭照料者与100名对照者比较研究表明,照料者的躯体功能、心理功能、社会功能与经济状况都显著差于对照者。照料者的生活质量与被照料者的病期、病情严重度、整体功能、药物副作用有关;同时,照料者身份为患者母亲者其生活质量受影响最大。  相似文献   

6.
李万秀 《医学信息》2008,21(12):2253-2255
目的 比较利培酮、氯氮平、奎的平3种非典型抗精神药对精神分裂症患者精神症状和生活质量的影响.方法 将108例精神分裂症患者随机分为3组,分别以利培酮(35例)、氟氮平(36例)、奎的平(37例)治疗并随访6个月,评定其临床症状和生活质量.结果 3种药物均能显著改善精神分裂症患者的临床症状和生活质量(P<0.05或P<0.01),疗效相似(P>0.05);但利培酮能显著改善患者心理状态、独立性、社会关系、环境状况和生活质量(P<0.05或P<0.01);奎的平显著改善患者心理状态和社会关系(均P<0.01);氯氮平仅显著改善心理状态(P<0.01).结论 在同样的治疗效果基础上,利培酮更有利于改善精神分裂症患者的生活质量.  相似文献   

7.
目的探讨护理干预对首发精神分裂症病人生活质量的影响。方法将80例首发精神分裂症病人随机分为研究组和对照组各40例,两组均予以利培酮系统治疗,研究组在此基础上,予以综合性护理干预措施,时间为8同,随后进行为期半年的随访,采用阴性症状与阳性症状量表(PANSS)及生活质量综合评定问卷(GQOLI)分别于治疗前及随访结束时进行评估。结果随访结束时,两组病人的PANSS总分及阴性、阳性症状评分均较治疗前明显降低(P〈0.01).但研究组明显优于对照组(P〈0.01);并且研究组GQOLI评分显著高于对照组(P〈0.01)。结论护理干预有助于改善首发精神分裂症病人的精神症状,提高其生活质量。  相似文献   

8.
综合干预对住院精神分裂症患者生活质量及预后的影响   总被引:17,自引:0,他引:17  
目的:探讨综合干预对住院精神分裂症患者生活质量及预后的影响。方法:将126例首发精神分裂症住院患者随机分为综合干预组(62例)和对照组(64例),在利培酮治疗的同时,对干预组予以综合干预措施,观察时间为8周,出院后随访一年。用阴性、阳性症状评定量表(PANSS)、生活质量量表(WHO,QOL-100)和复发率进行评估。结果:一年末随访时两组对精神分裂症阴性、阳性症状及PANSS总分均有改善,但干预组明显优于对照组;病人的生活质量两组均有改善,但干预组在生活质量总评、心理领域、独立性领域及社会关系领域的改善显著好于对照组;干预组的复发率、再住院率明显低于对照组。结论:对首发精神分裂症患者开展院内综合干预措施,更能改善患者的生活质量,降低复发率,有利于患者重返社会。  相似文献   

9.
目的:探讨利伯曼精神康复技术联合认知行为治疗(以下简称综合康复培训)对精神分裂症患者的服药态度和生活质量的作用。方法:对曾接受综合康复培训的180例精神分裂症患者应用服药态度问卷(Drug Altitude Inventory,DAI)及精神病人生活质量量表(Schizophrenia Quality of Life Scale,SQLS)在培训前和后(约3周)进行评估。结果:综合康复培训治疗前后比较,DAI分数升高(t=9.875,P0.001),SQLS的3个维度社会心理、动力精力,症状副作用的分数均下降,且差异有统计学意义(t=-5.831,-12.112,-7.373;P0.001)。相关性分析显示,DAI与性别、SQLS各维度改善程度均有显著性相关。结论:综合康复培训能显著地改善精神分裂症患者的生活质量,尤其动力精力及症状副作用,从而进一步改善患者对服用抗精神病药物的态度,促进患者早日回归社会。  相似文献   

10.
目的 :观察氯氮平与利培酮治疗对精神分裂症病人生活质量的影响。方法 :双盲对照研究。用阳性症状与阴性症状评定量表 (PANSS)观察病人的精神症状 ,用生活质量综合评定问卷 (GQOLI)分析病人生活质量。结果 :利培酮组的躯体健康维度、心理健康维度及社会功能维度得分明显高于氯氮平组 ,均有显著性差异 (P <0 0 1)。结论 :利培酮组精神分裂症病人生活质量优于氯氮平组。  相似文献   

11.
There is an established literature on the symptoms and complications of COVID-19 but the after-effects of COVID-19 are not well understood with few studies reporting persistent symptoms and quality of life. We aim to evaluate the pooled prevalence of poor quality of life in post-acute COVID-19 syndrome (PCS) and conducted meta-regression to evaluate the effects of persistent symptoms and intensive care unit (ICU) admission on the poor quality of life. We extracted data from observational studies describing persistent symptoms and quality of life in post-COVID-19 patients from March 10, 2020, to March 10, 2021, following PRISMA guidelines with a consensus of two independent reviewers. We calculated the pooled prevalence with 95% confidence interval (CI) and created forest plots using random-effects models. A total of 12 studies with 4828 PCS patients were included. We found that amongst PCS patients, the pooled prevalence of poor quality of life (EQ-VAS) was (59%; 95% CI: 42%–75%). Based on individual factors in the EQ-5D-5L questionnaire, the prevalence of mobility was (36, 10–67), personal care (8, 1–21), usual quality (28, 2–65), pain/discomfort (42, 28–55), and anxiety/depression (38, 19–58). The prevalence of persistent symptoms was fatigue (64, 54–73), dyspnea (39.5, 20–60), anosmia (20, 15–24), arthralgia (24.3, 14–36), headache (21, 3–47), sleep disturbances (47, 7–89), and mental health (14.5, 4–29). Meta-regression analysis showed the poor quality of life was significantly higher among post-COVID-19 patients with ICU admission (p = 0.004) and fatigue (p = 0.0015). Our study concludes that PCS is associated with poor quality of life, persistent symptoms including fatigue, dyspnea, anosmia, sleep disturbances, and worse mental health. This suggests that we need more research on PCS patients to understand the risk factors causing it and eventually leading to poor quality of life.  相似文献   

12.
The aim of the present study was to evaluate the impact of a violent environment on mental health and the impact of a sport for social development (SSD) program on quality of life, mental distress symptoms, and heart rate variability (HRV). HRV and psychometric data were measured from 20 men professional athletes assisted by the SSD and 20 men living in the same violent community. The comparison of groups revealed greater sympathetic parameters of HRV, positive affect, and quality of life in the SSD group. Multiple regression analysis showed that the quality of life in the SSD group was positively predicted by positive affect, while in the control group the quality of life was negatively predicted by their history of traumatic events. Both groups reported high levels of exposure to traumatic events and posttraumatic stress symptoms. However, this study demonstrates the benefits of SSD programs in mental health.  相似文献   

13.
This study examines the effects of depressive symptoms and mental health quality of life on utilization of highly active antiretroviral therapy (HAART) among HIV-seropositive women. Data were collected biannually from 1996 through 1998 in a prospective cohort study. Women reported use of antiretroviral therapy, health and mental health status, demographics, and social and behavioral factors; CD4 count and viral load also were assessed. Random effects regression models estimated the longitudinal effects of depressive symptoms and mental health quality of life on the probability of HAART utilization, controlling for clinical indicators (CD4 count, viral load, symptom presence), demographics (race, age, education), behavioral factors (drug/alcohol use, clinical trials participation), service features (insurance status, mental health service utilization), and study site. High levels of depressive symptoms and poor mental health quality of life were found, and they significantly reduced the probability of HAART utilization. Receiving mental health services significantly increased the probability of utilizing HAART. HIV-seropositive women characterized as being in poor mental health were less likely to use HAART, whereas those receiving treatment of mental health difficulties were more likely to use HAART. These findings suggest that efforts to enhance women's access to psychological treatment may increase their use of the latest HIV therapies.  相似文献   

14.
A total of 505 newborns who were exposed to illicit drugs during intrauterine life were studied to investigate the prevalence, growth parameters, newborn manifestations, and other effects of intrauterine exposure to cocaine and phencyclidine (PCP). The results support the hypotheses that both drugs have serious effects on growth parameters, but this effect was much more pronounced in the cocaine group than in the PCP group. Furthermore, the incidence of borderline microcephalic infants (head circumferences less than the 10th percentile) was much higher in the cocaine group. It also appears that the signs and symptoms observed in both groups are not withdrawal manifestations typically seen in narcotic-exposed infants; rather, these symptoms are true drug effects and should not be considered manifestations of drug withdrawal symptoms.  相似文献   

15.
There is little published literature on the correlation between subjective and objective efficacy of hypnotics. We wanted to determine whether there was a correlation between the patient's subjective evaluation of the efficacy of the hypnotic with the polysomnographic (PSG) findings. We studied 16 patients with chronic insomnia (sleep latency, greater than or equal to 30 minutes; total sleep time, greater than 240 but less than 420 minutes) for 11 nights who took placebos on nights 1 and 2, zolpidem (imidazopyridine) on nights 3-9 and placebo on nights 10 and 11. Patients completed a questionnaire each morning following PSG, which evaluated subjective sleep quality, sleep latency and total sleep time. These data were compared to PSG findings to answer specific questions about sleep latency reduction, efficacy of the hypnotic after a week's use, sleep quality after discontinuing the drug, and any correlation between subjective and objective measures. PSG findings indicated a shortened sleep latency, increased total sleep time, decreased total wake time and increased sleep efficiency when patients ingested zolpidem 30 minutes before bedtime. We found that after 7 nights (nights 3-9) the drug was still effective in reducing sleep latency and increasing total sleep time. Upon withdrawal (nights 10 and 11) sleep returned to baseline (nights 1 and 2). Subjectively, the patients confirmed those findings on the questionnaire, as well as a subjective reduction in the number of awakenings and, interestingly, a subjective increase in the time spent awake after sleep. Many of the objective variables we examined correlated highly with the subjective variables. While on zolpidem, subjects believed and were objectively shown to have a decreased sleep latency, increased total sleep time and decreased time awake before persistent sleep, although they tended to overestimate sleep latency and time spent awake before persistent sleep and underestimated total sleep time. Although the correlation between objective and subjective measures was high for the group, in individual patients there was an impressive difference between the two, and the highest coefficient of variation between a subjective and objective measures was 0.453. No correlations were found with subjective measures of refreshing quality of sleep, decrease in number of awakenings, how sleepy patients felt in the morning or their ability to concentrate in the morning. Thus, we believe the PSG remains the keystone in the evaluation of hypnotic efficacy.  相似文献   

16.
BACKGROUND: Allergic rhinitis is a disease impairing quality of life, sleep, and work. A new classification for allergic rhinitis, Allergic Rhinitis and its Impact on Asthma (ARIA), has recently been proposed. OBJECTIVE: To study the effect of allergic rhinitis using ARIA definitions to determine severity and duration. METHODS: A total of 3052 patients consulting general practitioners for allergic rhinitis were studied. Patients were classified according to the 4 classes of ARIA. In all patients, quality of life (Rhinoconjunctivitis Quality-of-Life Questionnaire), sleep (Jenkins questionnaire), and work performance (Allergy-Specific Work Productivity and Activity Impairment questionnaire) were assessed. RESULTS: Mild intermittent rhinitis was diagnosed in 11% of the patients, mild persistent rhinitis in 8%, moderate/severe intermittent rhinitis in 35%, and moderate/severe persistent rhinitis in 46%. The severity of rhinitis has more of an effect on quality of life, sleep, daily activities, and work performance than the duration of rhinitis. In moderate/severe rhinitis, more than 80% of patients report impaired activities, as opposed to only 40% with mild rhinitis. CONCLUSION: It seems that the term moderate/severe should be replaced by severe. A study in the general population is necessary, however, to assess the prevalence of the 4 ARIA classes of allergic rhinitis, especially in patients who are not consulting physicians for their symptoms.  相似文献   

17.
Nicotine may be used to manage negative emotions, and recent research suggests that smokers with high levels of hostility may use cigarettes to cope with anger provoking situations. This study evaluated the extent to which a high level of trait anger is associated with risk for relapse among smokers interested in cessation. Chronic smokers with different levels of trait anger provided reports of withdrawal symptoms, craving, and state anger, and collected saliva samples for cortisol during 24-hour ad libitum smoking and the first 24-hour abstinence period of a quit attempt. They also attended a laboratory session conducted after the 24-hour abstinence during which they performed brief mental and social stress challenges and provided blood samples for adrenocorticotropin (ACTH) and cortisol assays. High trait anger was associated with greater increases in state anger, withdrawal symptoms, and craving during the first 24 h of abstinence. It was also associated with greater ACTH concentrations during the laboratory session. High trait anger was also associated with increased risk for early relapse. The findings support the hypothesis that smokers high in anger trait may have greater mood difficulties during abstinence and may be more vulnerable to early relapse than smokers with low anger trait.  相似文献   

18.
Withdrawal reaction after long-term therapeutic use of benzodiazepines   总被引:6,自引:0,他引:6  
We conducted a double-blind, placebo-controlled trail in which 40 patients who had undergone long-term therapy with benzodiazepines were switched to placebo or to diazepam in a dose approximately equivalent to their usual dose of the benzodiazepine; the dose of diazepam was then tapered during an eight-week period. Patients were assessed clinically and psychologically and had weekly sessions of behavioral therapy. The subjects who received placebo had more symptoms, assessed their symptoms as more severe, and stopped taking the study drug at a higher rate than those receiving the tapering doses of diazepam. The subjects in the placebo group also had symptoms shortly after being switched to placebo, whereas those in the diazepam group had symptoms much later. Some withdrawal symptoms were distinct from those of anxiety (e.g., tinnitus, involuntary movement, and perceptual changes). Withdrawal symptoms occurred earlier in patients who had received short-acting benzodiazepines than in those who had received long-acting benzodiazepines. Symptoms gradually disappeared over a four-week period in both the placebo and the diazepam groups. Serial determination of plasma benzodiazepine concentrations was a useful way to assess compliance, treatment outcome, and relapse during withdrawal. We conclude that a clinically important, mild, but distinct withdrawal syndrome occurs after discontinuation of long-term therapeutic use of benzodiazepines.  相似文献   

19.
An effective rehabilitation program was developed for psychiatric patients' self-management of medication and symptoms. The rehabilitation program was designed to allow the patients to understand their illness, cope with their medical regimen, and prevent a relapse by recognizing any of the symptoms when they recur. This study consisted of three phases. The first phase was to explore the extent and the specific mental health needs of psychiatric patients. Data was obtained from 82 subjects who had symptoms of a mental illness including schizophrenia, bipolar disorders, and delusional disorder. They had received medication instruction during their hospitalization. The subjects were at the time outpatients in a psychiatric hospital. In the second phase, the researchers developed an educational program focused on coping with the residual and relapse warning signs, managing the drug side effects, medication compliance, and daily routines, according to the information acquired in the first step. The developed program includes the self-efficacy method reported by Bandura, including manuals and videotapes focusing on real life situations, small group discussions, and telephone coaching. Finally, the researchers investigated the effects of this program. Thirty-eight patients were selected for this study, 18 in the experimental program and 20 as controls. The diagnoses were same as those with the first step. The results showed that the subjects who attended this educational program reported significantly more improvement in self-efficacy (p=0.014) and medication compliance (p= 0.005), and significantly less relapse warning symptom scores (p=0.000) than the controls. In conclusion, these instructional materials will be beneficial for medication and symptom management in rehabilitating psychiatric patients in Korea. In addition, the materials may be a useful psychoeducational resource for professionals in the field of clinical psychiatry.  相似文献   

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