起搏器患者生存质量量表的编制及信效度分析

目的 编制与考评起搏器患生存质量量表的信度和效度。方法 采用选题小组和专题小组的程序化及决策起搏器患生存质量测定量表并通过随机抽取200例起搏器患的生存质量测定资料对量表进行信度和效度的考评。结果 体，心理，社会，一般认识4大领域和是表总分的重测相关系数分别为0.875,0.856,0.816.0.910和0.815,分半信度为0.873大领域的克朗巴赫系数（Cronbach α coefficients)分别为0.866,0.893,0.879和0.823。量表的结构与设计时的概念相吻合，SF－36量表为效标进行评估，其效标为0．812。结论 起搏器患生存质量的量表具有较好的信度和和效度，可作为我国起搏器生存质量的测评工具。     

中华生存质量量表的信度和效度

目的:考评中华生存质量量表的信度和效度,使其能够在临床和科研研究中应用。方法:选择2003-01/06广州中医药大学第一附属医院和宁夏医学院附属医院的193例慢性疾病患者和广东广州和宁夏银川两地的社区人群(80例健康者),在调查过程中,除了使用中华生存质量量表外,同时也让调查对象填写世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版。所有量表都由调查对象自己填写完成。计算该量表的内部一致性信度,重测信度,结构效度,内容效度、效标效度和区分效度等。其中效标效度以世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版作为效标。结果:273份问卷均进入结果分析。量表的所有方面和领域的克朗巴赫α系数都大于0.7;方面的重测相关系数0.67～0.84,领域0.83～0.90;拟合优度指数除领域情(0.872)和方面气候适应(0.820)之外,其他均大于0.9;与世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版相比,各领域之间存在很好相关性。结论:中华生存质量量表是一份较好的用于测定生存质量的量表,具有较好的信度和效度,可以应用于临床和科研研究。     

中华生存质量量表的信度和效度

目的：考评中华生存质量量表的信度和效度，使其能够在临床和科研研究中应用。 方法：选择2003-01／06广州中医药大学第一附属医院和宁夏医学院附属医院的193例慢性疾病患者和广东广州和宁夏银川两地的社区人群（80例健康者），在调查过程中，除了使用中华生存质量量表外。同时也让调查对象填写世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版。所有量表都由调查对象自己填写完成。计算该量表的内部一致性信度，重测信度，结构效度，内容效度、效标效度和区分效度等。其中效标效度以世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版作为效标。 结果：273份问卷均进入结果分析。量表的所有方面和领域的克朗巴赫α系数都大于0．7；方面的重测相关系数0．67～0．84，领域0．83～0．90；拟合优度指数除领域情（0．872）和方面气候适应（0．820）之外，其他均大于0．9；与世界卫生组织生存质量测定量表中文版和健康状况调查问卷中文版相比，各领域之间存在很好相关性。 结论：中华生存质量量表是一份较好的用于测定生存质量的量表，具有较好的信度和效度，可以应用于临床和科研研究。     

EORTC QLQ-C30中文版测定卵巢癌患者生存质量的评价

目的:对用欧洲癌症研究与治疗组织生存质量问卷第3版(EORTC QLQ-C30 V3.0)简体中文版测定我国卵巢癌患者生存质量的心理测量学特性进行考评,为卵巢癌患者的生存质量评价提供依据。方法:采用调查问卷方式,应用EORTC QLQ-C30 V3.0中文版,对2002年1月—2005年12月在北京协和医院就诊的卵巢癌化疗期、恢复期患者各60例进行生存质量测定,并以60例健康妇女作为对照,考评该量表测定卵巢癌患者生存质量的信度和效度。结果:量表的重测信度相关系数r在各个领域均为0.8以上。内部一致性信度的克朗巴赫系数α均在0.8以上。主成分分析显示中文版量表与英文版量表的结构符合。方差分析显示量表能够很好地区分不同组别妇女的生存质量。卵巢癌化疗组在不同领域的生存质量均显著低于恢复组和健康组(P<0.001)。卵巢癌恢复组整体健康状况、躯体功能、角色功能、情绪功能和社会功能评分仍较健康组低(P<0.001),乏力症状和经济领域评分也较健康组有显著差异(P<0.001)。结论:EORTC QLQ-C30 V3.0简体中文版具有良好的信度和效度,可作为我国卵巢癌患者生存质量的测评工具。     

特发性肺纤维化患者生活质量特异性量表的汉化及信度效度的初步验证

目的：形成中文版特发性肺纤维化患者生活质量特异性量表（ATAQ-IPF）,并检验其在中国特发性肺纤维化患者中的信度、效度。方法：取得原作者同意并授权后,将量表进行翻译、回译和文化调试,应用翻译和修订的中文版量表ATAQ-IPF和圣乔治呼吸问卷（SGRQ）对75名特发性肺纤维化患者进行调查,采用项目分析方法测定中文版ATAQ-IPF量表各条目的鉴别能力,进行重测信度、内部一致性信度、内容效度、效标关联效度的初步评定。结果 ：中文版ATAQ-IPF量表含74个条目,除条目49外,各条目与其所属维度的相关系数为0.305~0.962;ATAQ-IPF量表与圣乔治呼吸问卷（SGRQ）的效标关联效度为0.611（P〈0.01）;Cronbach’sα系数为0.945。结论：中文版量表ATAQ-IPF有较好的信度、效度,可用于评价特发性肺纤维化患者的生活质量。     

腹膜透析患者生活质量量表的编制与信效度检验

目的 :编制适合我国文化背景的腹膜透析生活质量量表。方法 :通过文献检索及患者访谈分别构建量表条目池;应用Delphi专家咨询法、条目分析、变异系数、条目间相关系数、条目与维度间相关系数、内部一致性系数、因子分析等对量表条目进行筛选,并进行信效度检验。结果 :量表一周后重测信度为0.781;Cronbach’sα系数为0.936,显示量表具备较好的信度。与SF-36做效标关联度时,两量表总分的相关系数为0.956。对量表结构效度考评时,通过主成分因子分析提取了10个公因子,公因子的分布与维度间的联系符合前期理论构想及预期结果。结论 :形成的腹膜透析患者生活质量量表有较好的信效度,可在我国腹膜透析患者生活质量的测评中推广应用。     

中文版斜视儿童生存质量量表的信度和效度研究

目的 研究中文版斜视儿童生存质量量表(Child Intermittent Exotropia Questionnaire,Child-IXTQ)的信度和效度.方法 采用Brislin翻译模型对Child-IXTQ进行汉化,经专家组及预试验调适条目形成Child-IXTQ最终版,然后选取108例斜视患儿进行调查.采用项目分析、内容效度、结构效度、效标关联效度、反应度、内部一致性系数、重测信度对量表的信效度进行分析.结果 项目分析结果显示,各条目得分与量表总分均相关(r=0.377～0.763,P＜0.01);量表总的内容效度指数(CVI)为0.93;两个维度得分与总分的相关系数为0.709～0.937,差异具有统计学意义(P＜0.01);探索性因子分析提取2个公因子,共解释了60.034％的总方差:效标关联效度系数r为0.517(P＜0.0);手术前后斜视患儿的生存质量评分差异有统计学意义,从而显示出较好的反应度.量表总的Cronbach's α系数为0.848,各条目重测信度为0.728～0.913.结论 中文版Child-IXTQ具有良好的信度和效度,适合中国斜视患儿生存质量的测评.     

简式中文版Oswestry功能障碍指数评定下背痛患者的信度及效度分析

目的研究简式中文版Oswestry功能障碍指数(SCODI)评定腰骶部慢性骨筋膜间隔综合征(LCCS)所致下背痛(LBP)患者手术疗效的信度及效度。 方法共选取140例LCCS所致LBP患者,根据其病情给予腰骶部切开减压术治疗。于术前、术后采用SCODI、Roland-Morris功能障碍问卷量表(RDQ)及目测类比评分法(VAS)对患者进行评定,并对SCODI的信度及效度进行分析,其中信度分析指标包括：①Spearman-Brown折半信度;②内部一致性Cronbach′s α系数,重测信度内部相关系数（ICC）。效度分析指标包括：Spearman相关系数（分析效标效度）及因子分析（分析构架效度）,并与RDQ、VAS及世界卫生组织国际功能、残疾与健康分类（ICF）核心要目进行相关性分析。 结果信度分析：SCODI量表Spearman-Brown折半信度系数为0.746,Cronbach′s α系数为0.884,重测信度ICC为0.907,提示量表信度理想;效度分析：SCODI量表KMO值为0.82,术前与RDQ、VAS、ICF核心要目的Spearman相关系数分别为0.783,0.945和0.865,术后分别为0.880,0.915和0.548,提示SCODI量表效标效度及结构效度理想。 结论SCODI量表评定LCCS所致LBP患者具有较好的信度及效度,可作为决策腰痛功能障碍患者是否需要手术以及评定手术疗效的重要参考指标。     

生活质量测定量表简表在神经症患者中应用的信度及效度研究

目的:评价世界卫生组织生活质量测定量表简表(WHOQOL-BREF)在神经症患者中的信度和效度。方法:由专业医生对同济大学附属同济医院精神医学科门诊及住院初诊患者53例行健康状况调查问卷(SF-36),WHOQOL-BREF评定,在治疗的第4周予以重测。对量表的内部一致性、重测信度、劈半信度及效标关联效度等指标进行分析。结果:WHOQOL-BREF的Guttman劈半信度为0.840,Cronbach'sα系数为0.763,各维度的Cronbach'sα系数较好,重测后各项目的相关系数为0.348～0.761。WHOQOL-BREF各维度分与SF-36的各维度分除生理功能和生理职能,以及社会关系领域分和躯体疼痛、情感职能外,均呈明显相关。结论:WHOQOL-BREF具有较好的信度和效度,部分分量表能较好反映神经症患者的情绪状态,基本适用于神经症患者生活质量评价。     

中文版痴呆心境评估量表的信效度研究

目的 翻译痴呆心境评估量表(Dementia Mood Assessment scale,DMAS),并对其信、效度进行初步评价.方法 翻译并修订DMAS,用中文版DMAS对133例老年期痴呆患者进行调查,对测定结果进行信、效度分析.结果 中文版DMAS的内容效度CVI值为0.95;以老年性痴呆生活质量量表(Quality of Life-Alzheimer's Disease scale,QOL-AD)为效标,其效标关联效度为-0.77;因子分析萃取了4个公因子,方差累计贡献率为54.95%.量表的Cronbach's α系数为0.81,重测信度为0.94,评定者信度为0.93.结论 中文版DMAS信、效度较好,可用于评价中国老年期痴呆患者的心境状况.     

Field testing the WHOQOL-100 in Canada.

The purpose of this project was to test the WHOQOL-100, an instrument for assessing quality of life (QOL), developed to facilitate cross-cultural comparison. The instrument was tested with a convenience sample of 144 people. The mean age of participants was 58 years and 41% were female.Test-retest reliability was .86 for the physical domain, .78 for the psychological domain, .91 for independence, .87 for social relationships, .77 for environment, and .60 for spirituality. Consistency reliability was .77 for physical, .79 for psychological, .89 for independence, .71 for social relationships, .80 for environment, and .89 for spirituality/ personal beliefs. Correlations of the various domains with other instruments, including the SF-36, the Self-Anchoring Striving Scale, and the Visual Analogue Scale for Pain, supported the convergent validity of the instrument. The instrument was able to discriminate between healthy and ill populations, providing support for construct validity.     

SF-36量表测量伤残人员生存质量的信度与效度

目的 评价SF-36量表在测量地震伤残人员生存质量中的信度和效度.方法 利用自填法及访谈相结合的方式调查201例绵竹市某镇地震伤残人员,用重测信度和Cronbach's a系数分析SF-36信度;因子分析方法分析效度.结果 SF-36各领域的重测信度分别为:生理功能(PF)0.78、生理问题对功能的限制(RP)0.85...     

Development and validation of a quality of life instrument for patients with drug dependence: comparisons with SF-36 and WHOQOL-100

Aim

Our goal was to develop a self-administered quality of life scale for patients with drug addiction/dependence (QOL-DA) and compare it with the SF-36 and the WHOQOL-100.

Methods

Employing theory and methodology of rating scale construction, a self-administered quality of life instrument for individuals with drug dependence QOL-DA was developed and evaluated utilizing responses from 212 drug-dependent subjects at the Kunming Municipal Mandatory Detoxification and Rehabilitation Center in China. Quality of life was measured using the SF-36, WHOQOL-100 and QOL-DA three times during the detoxification.

Results

Test-retest reliability in the domains of physical function, psychological function, social function and toxicity were 0.82, 0.64, 0.78, and 0.76, respectively. Cronbach's coefficient α for the 4 domains was 0.87, 0.89, 0.93 and 0.86, respectively. Correlations and factor analysis showed good construct validity. Criterion-related and convergent validity was confirmed by using the SF-36 and the WHOQOL-100 simultaneously. The instrument does show the change in QOL after two weeks of detoxification with higher standardized response mean higher than that of SF-36 and WHOQOL-100.

Conclusion

The instrument developed has good validity, reliability and better responsiveness than instruments currently used, and can be employed effectively to measure the quality of life of individuals with drug dependence.     

Construct and criterion validity of the SF‐12 health questionnaire in patients with acute myocardial infarction and unstable angina

Background The aim of the study was to determine the construct and criterion validity of the 12‐item short‐form questionnaire (SF‐12) in coronary patients with either acute myocardial infarction or unstable angina in Spain. Method A total of 186 patients hospitalized with coronary heart disease have been studied. The construct validity has been analysed by means of the association between the SF‐12v.1 and sociodemographic and clinical variables; and the criterion validity was tested by the correlations between 36‐item short‐form question (SF‐36) and SF‐12 summary scores. The equivalence between both health questionnaires was examined by means of the proportion of variance in the SF‐36 physical and mental component summary (PCS‐36 and MCS‐36) scores explained by the 12 items adjusted by age and sex. Results The validation result was as expected: female patients and those with poor education level, worse mental health, unstable angina, cardiovascular risk factor and co‐morbidity obtained a lower score in the SF‐12. The correlations between SF‐36 and SF‐12 summary scores were high. The equivalence between the SF‐12 and SF‐36 was good, because the models explained 87% of the variation in PCS‐36 score and 93% of the variation in MCS‐36. Conclusion The SF‐12 is a valid tool in studies assessing health‐related quality of life in coronary patients. The use of the SF‐12 may be especially useful in patients where the clinical situation make difficult the application of the longer instrument.     

Evaluation of a Swedish Version of the Ostomy Adjustment Scale

The main aim of the present study was to adapt an instrument measuring patients' adjustment to life with an ostomy to Swedish conditions and to test reliability and validity of the adapted instrument. The Ostomy Adjustment Scale (OAS), which is focused on three domains: physical function, psychologic state, and social interaction, was selected as suitable. After translation into Swedish, equivalence and internal consistency of the scale were calculated. Subjects with various types of urine or faeces diversions were recruited for self-rating with the OAS and a visual analogue scale estimating total quality of life (QOL). The instruments were tested in 48 patients with five different diagnoses, 36 with and 12 without ostomy, and re-tests were carried out in 25 of the patients. Reliability (Cronbach's alpha) was 0.95. A positive correlation was found between the OAS and QOL (r = 0.67), indicating that the instrument has some validity.     

《国际功能、残疾和健康分类》乳腺癌核心功能组合评定乳腺癌患者生活质量的可行性研究

评价《国际功能、残疾和健康分类》（ICF）乳腺癌核心功能组合在中国乳腺癌患者中使用的可行性。采用ICF乳腺癌核心功能组合及简明健康测量量表（SF-36）评估110例乳腺癌患者的生活质量,比较两种量表的可信性、有效性及可行性。其中被测者信度、克朗巴赫系数、内部一致性信度、分半信度反映量表可信性,准则关联效度、结构效度反映量表有效性,量表完成率及完成时间反映量表可行性。 结果ICF乳腺癌核心功能组合具有较好的可信性、较高的有效性和符合量表要求的可行性。ICF乳腺癌核心功能组合适用于中国乳腺癌患者。     

慢性失眠患者失眠程度、抑郁情绪与生活质量的相关性

目的 通过探讨慢性失眠患者失眠严重程度、抑郁情绪与生活质量的相关性,评估影响患者生活质量的主要因素.方法 连续收集126例成年慢性失眠患者,根据失眠严重程度指数量表(ISI)得分分为亚临床、中度、重度失眠三组,根据贝克抑郁问卷(BDI)得分分为伴和不伴抑郁两组,用SF-36健康调查量表(SF-36)评分,分别对生活质量进行比较.结果 失眠程度重的患者SF-36(除机体疼痛外)得分低(P<0.01);伴有抑郁情绪的患者SF-36(除机体疼痛外)得分低(P<0.05);相关性分析得出ISI得分与SF-36(除机体疼痛外)得分呈负相关(P<0.05),BDI得分与SF-36得分呈显著负相关(P<0.01);控制BDI变量偏相关分析,ISI得分与SF-36(生理功能、生理职能、总体健康、活力和生理健康)得分呈负相关(P<0.05);控制ISI变量偏相关分析,BDI得分与SF-36得分(除生理机能和机体疼痛外)呈显著负相关(P<0.01).结论 慢性失眠患者失眠严重程度与生活质量相关,但与慢性失眠相关的抑郁情绪起到主要作用,这提示慢性失眠治疗中应注重改善患者情绪问题.     

Developing an instrument to measure quality of life of patients with hyperhidrosis

Quality of life (QOL) is an index of the state of wellness of an individual. The purpose of this study was to develop an instrument to measure quality of life of patients with hyperhidrosis. With a multi- dimensional model of QOL as the conceptual framework for instrument development, the study started from literature review which was followed by interviews with patients, staff nurses, and doctors to generate the original items for the instrument. The validity and reliability then were assessed. Six experts performed content validity (CVI =.70). Internal consistency and construct validity assessment followed. A quantitative research method was used in this study. During March 2002 to April 2003, 85 patients from the surgical outpatient clinic at a teaching hospital in southern Taiwan were purposively recruifed as subjects. Written consent was obtained before subjects answered a questionnaire that should take 8-10 minutes to finish. Data analysis was performed using SPSS for Windows 8.0. Mean, standard deviation, frequency, percentage, Cronbach ' s alpha, Pearson ' s correlation, and factor analysis were used to analyze the data. Exploratory factor analysis identified five factors. They were functional, social interaction, personal affective, psychological and physical function. The coefficients of Cronbach ' s alpha for these five factors ranged from 0.71 to 0.94. These five factors explained 68.90 % of the variance in QOL among the patients with hyperhidrosis. The results showed that the instrument had satisfactory validity and reliability. Implications of these results for future studies were discussed.     

腹膜透析患者的生活质量与营养不良和慢性炎症的相关性研究

目的了解持续不卧床腹膜透析(continuous ambulatory peritoneal dialysis,CAPD)患者的营养不良、慢性炎症对其生活质量的影响。方法本研究为横断面研究。调查2009年1月至5月在中山大学附属第一医院透析中心随访的CAPD患者的营养不良、慢性炎症和生活质量,并分析其相互关系。其中以主观综合性营养评估(subjective global assessment,SGA)作为营养状况的标准,血C反应蛋白(C-reactiveprotein,CRP)水平为慢性炎症的指标,健康相关的生命质量量表(SF-36)评分结果作为患者生活质量的指标。结果在CAPD患者的生活质量与营养不良、慢性炎症的相关性分析中,营养不良与生理机能、躯体疼痛、总体健康状况、精力、社会功能、精神健康相关,其相关系数分别为:0.287,0.225,0.344,0.348,0.286,0.227(P0.01),而血CRP水平分别与生理机能、生理职能、躯体疼痛、总体健康状况、精力、社会功能负相关,相关系数分别为:-0.359,-0.178,-0.271,-0.253,0.236,-0.198(P0.01)。结论营养不良和慢性炎症状态从生理机能、精力、和社会功能等方面影响CAPD患者的生活质量。要提高CAPD患者的生活质量,在改善患者的营养状态的同时要注意纠正慢性炎症状态。