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LA function evaluated on 3DE imaging or speckle-tracking echocardiography, but not LA volume, is an independent predictor of new-onset AF in patients with Chagas disease. The reservoir component of LA function measured on 3DE imaging (total LA emptying fraction < 51.8%) can identify a population at high risk for AF as depicted by the cumulative survival curves.
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Progression to severe MAC and CMVD according to MAC severity and sex.
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