正颌外科技术治疗TMJ后OSAS(英文)

目的 评估正颌外科技术矫治14例颞颌关节强直所致OSAS的效果。方法 手术采用患侧关节成形,下颌升支、体部的“L”形半层截骨及健侧矢状截骨术,将患侧下颌升支加高固定,下颌前部整体前移。结果14例颞颌关节强直伴OSAS患者术后张口度达2.5～3.5cm,术后2年随访张口度仍维持在2.5～3.2cm之间。所有患者的AHI指数下降了20以上,12例患者的打鼾症状消失,持续血氧饱和度平均提高了18.45％（P<0.01）,达到了正常人的范围,持续血氧饱和度最低值由术前的58％提高至术后的95％以上,OSAS得以治愈。结论 颞颌关节强直伴OSAS患者通过正颌外科手术可以在关节成形的同时,解决患者下颌后缩的缺陷,解除上气道狭窄,从而缓解或纠正患者的低氧血症。     

治疗颞颌关节强直后SAS的新方法及手术效果的评价

目的：用L值评估正颌外科技术矫治的12例颞颌关节强直所致SAS的效果。方法：手术采用患侧关节成形，下颌升支、体部的“L”型半层截骨及健侧矢状截骨术，将患侧下颌升支加高固定，下颌前部整体前移。上 颌骨Lefort I型截骨，向健侧旋转，纠正偏移，并行颏成形术。比较分析术前、术后的L值。结果：12例颞颌关节强直所致OSAS患者术后张口度达2．5－3．5cm，连续血氧饱和度最低值由术前的58％提高至术后的95％以上，术后L值较术前L值有较大的提高，术后AKI指数较术前AHI指数大幅下降，OSAS得以治愈。结论：颞颌关节强直所致OSAS患者通过正颌外科手术可以在关节成形的同时，解决患者下颌后缩的缺陷，解除上气道狭窄，从而缓解或纠正患者的低氧血症。     

颞下颌关节强直的牵引成骨治疗

目的探讨牵引成骨技术在颞下颌关节强直治疗中的应用。方法应用内置式牵引器治疗8例单侧颞下颌关节强直患者,患侧升支区制备一个1.5～2.0cm颊舌向等宽的骨间隙,并去除喙突,恢复开口度,升支后缘方块截骨,截骨块保留翼内肌附着,与下颌骨间安装牵引器,术后采用升支牵引成骨术,每日牵引1mm,分2次完成,重建颞下颌关节结构及恢复颞下颌关节功能,并坚持开口训练18个月以上。结果经牵引成骨后,患者牵引间隙成骨良好,新形成的关节形态得到改建,升支高度延长1.2～2.1cm,开口度达到正常。结论牵引成骨是治疗颞下颌关节强直的有效方法。     

正颌外科技术治疗颞颌关节强直后睡眠呼吸暂停综合征(附9例报告)

目的：评估用正颌外科技术矫治９例颞颌关节强直所致睡眠呼吸暂停综合征的效果。方法：采用患侧关节成形,下颌升支、体部的“Ｌ”型半层截骨及健侧矢状截骨术,将患侧下颌升支加高固定,下颌前部整体前移。结果：９例颞颌关节强直后睡眠呼吸暂停综合征患者术后张口度达２．５～３．５ｃｍ,连续血氧饱和度最低值由术前的５８％提高至术后的９５％以上,唾眠呼吸暂停综合征得以治愈。结论：颞颌关节强直后睡眠呼吸暂停综合征患者通过正颌外科手术可以在关节成形的同时,解决患者下颌后缩的缺陷,解除上气道狭窄,从而缓解或纠正患者的低氧血症。     

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目的观察采用下颌升支垂直截骨上推术治疗真性颞颌关节强直的疗效。方法对2004年12月至2008年5月山西医科大学第一临床医院口腔颌面外科收治的19例真性颞颌关节强直患者采用下颌升支垂直截骨上推术治疗,并按期随诊,监测指标,观察其疗效。结果所有患者张口度均接近或达到正常,无关节疼痛及弹响症状,随访期内无一例复发。结论根据国内外文献及术后观察,下颌升支垂直截骨上推术是治疗真性颞颌关节强直的一种可选择的、有效的方法。     

牵张成骨联合正颌正畸治疗成人严重小下颌畸形

目的：探讨牵引成骨技术联合正颌正畸治疗重度小下颌伴偏颌畸形患者下颌骨严重发育不足及咬合关系紊乱的疗效。方法：对2例继发于儿童时期颞下颌关节损伤的小下颌伴偏颌畸形患者采用牵张成骨技术进行治疗。手术行双侧下颌角处截骨,安置牵引器,延长下颌升支及下颌体。第二期在拆除牵引器后进行正畸治疗,继而采用正颌外科方法进一步矫正颌面畸形及咬合关系,术后正畸治疗矫正咬合关系,排齐牙列。结果：2例患者均顺利完成治疗。下颌骨最小牵引距离25 mm,最大牵引距离30 mm,牵引区成骨良好,SNB角由术前平均67°增加到术后80°,小下颌及偏颌畸形得以矫治。联合正颌外科及正畸治疗后,面形及咬合功能均获得满意效果。术后经过2年6个月随访,未见复发。结论：联合应用牵张成骨和正颌外科技术并配合正畸治疗是矫治成人重度小下颌不对称性牙颌面畸形的有效治疗方案。     

口内下颌骨升支垂直截骨倒置治疗颞下颌关节强直

目的：应用口内下颌骨升支垂直截骨倒置及耳前切口去除骨球关节窝成形术治疗颞下颌关节真性强直,评价其重建颞下颌关节的效果。方法：对5例颞下颌关节骨性强直患者切除病变区骨质,形成关节窝,采用口内下领骨升支垂直截骨倒置升支后部构造新的”髁突”,重建颞下颌关节。手术后常规随访,评价其疗效。结果：全部病例术后随访3～24个月,开口度3．1～4．1cm,平均开口度3．6cm,效果满意。结论：应用口内下颌骨升支垂直截骨倒置及耳前切口去除骨球关节窝成形术治疗颞下颌关节真性强直具有多方面优势,减少了并发症的发生,是治疗颞下颌关节真性强直的有效手术治疗方法。     

正颌外科治疗颞下颌关节强直伴阻塞性睡眠呼吸暂停综合征

目的 评价正颌外科手术治疗颞下颌关节强直伴阻塞性睡眠呼吸暂停综合征(OSAS)的效果。方法 12例颞下颌关节强直伴OSAS患者(男4例，女8例，年龄10～25岁，平均18．4岁；双侧颞下颌关节强直8例，单侧颞下颌关节强直4例)，采用颞下颌关节成形术、下颌矢状劈开前徙术、颏前徙成形术、舌骨悬吊术以及牵张成骨术移动下颌骨和舌骨。术后随访3～36个月。结果 12例患者张口度由术前的0～2mm增大到术后25～40mm；术后患者颜面形态明显改善；其连续血氧饱和度最低值由术前的42％提高至术后的90％以上，睡眠呼吸障碍解除和睡眠质量获得提高。结论 在颞下颌关节强直伴OSAS患者的治疗中，行颞下颌关节成形术的同时，辅助正颌外科手术，不仅可以增大患者的张口度，而且还能解决患者下颌后缩的畸形，同时解除上气道狭窄，从而缓解或纠正患者的低氧血症。     

应用下颌升支后缘及下颌角骨块倒置术行颞颌关节成形

我们从1986年起,对6例颞颌关节强直的病人采用了患侧升支“[”形截骨倒置颞颌关节成形术,用下颌角形成新的髁状突隔离骨断面,防止了术后再粘连,并前移了下颌骨,矫正了下颌后缩畸形,在临床上收到了良好的效果。     

颞下颌关节强直伴颏畸形的同期外科处理

颞下颌关节强直的外科治疗文献报导较多，我科自1989年5月～1995年5月对17例颞下颌关节强直合并小下颌，或（和）倔颌的畸形患者，在作下颔升支后缘垂直截开倒置行关节重建术的同时，切取喙突和部分下颌升支骨块，移植于领部骨截开前徙的骨创内行额成形术，获得了满意的疗效。现报告如下：临床资料1对象17例颞下颌关节强直合并颁畸形患者，在关节重建术的同时完成额成形术。17例中男7例，女10例；年龄最大38岁，最小13岁；I型关节强直3例，11型8例，皿型6例；术前张日度0～0·2cm者9例，0．2～0．5cm者8例；单侧关节强直10例，双侧关节强直…     

Simultaneous costochondral graft and distraction osteogenesis in unilateral TMJ ankylosis associated with mandibular retrognathia and asymmetry

The purpose of this study was to review the long-term effect of simultaneous costochondral graft (CCG) and distraction osteogenesis (DO) in the management of unilateral temporomandibular joint ankylosis associated with severe dentofacial deformities in our clinic. In addition, we sought to analyze the advantages and disadvantages of CCG and DO. Four patients were included in this clinical study during 2005 to 2007. The mean length of ankylosis history was 14.5 years. All patients had significant mandibular retrognathia and asymmetry histories and have been diagnosed with obstructive sleep apnea syndrome by a polysomnogram before surgery. A 1-stage surgery, with gap arthroplasty, CCG, and mandibular DO, was performed. The surgical plan and technique were reviewed. No severe complications were observed after surgery. Distraction was started on day 7 after surgery. The distance of distraction ranged from 20 to 25 mm (mean, 22.5 mm). Mouth opening was increased from 25 to 37 mm (mean, 33.5 mm) during the follow-up period (range of 3.5-5 y). No recurrence of joint ankylosis occurred based on the clinical and radiographic evaluations. All of the patients had significant improvement in obstructive sleep apnea syndrome after surgery. Mandibular asymmetry and retrognathia were well corrected in all of the patietns. In conclusion, a 1-stage surgical treatment with DO and CCG demonstrated its feasibility and effectiveness in management of temporomandibular joint ankylosis combined with severe dentofacial deformity. It is a safe and reliable method of treatment.     

牵引成骨技术治疗小下颌畸形伴OSAS效果的初步报告

目的分析评价下颌骨牵引延长治疗小下颌畸形伴阻塞性睡眠呼吸暂停综合征后,患者上呼吸道、睡眠呼吸暂停指数及血的变化,方法 对５例小下颌畸形伴ＯＳＡＳ患者应用口内型牵引器行牵引颌骨牵引成骨管长下颌骨体、前伸下颌骨、扩大咽腔。结果 ５例下颌骨体最大牵引幅度为２４．４０ｍｍ最小牵引幅度８．５０ｍｍ。在小颌畸形得到明显改善的同时,患者咽腔扩大,睡眠呼吸暂停指数明显下降,血氧饱和度显著上升。最长随访时间１１个月     

A case of improved obstructive sleep apnea by distraction osteogenesis for midface hypoplasia of an infantile Crouzon's syndrome

We performed Le Fort III midfacial advancement with gradual distraction using internal devices on a 2-year 5-month-old boy with Crouzon's syndrome with associated severe obstructive sleep apnea. The device was not activated until 7 days after surgery, after which the distraction was initiated, 1 mm per day, and the midface was advanced 4 mm intraoperatively and distracted 12 mm postoperatively. A total advancement of 16 mm was obtained. The obstructive sleep apnea improved remarkably after the distraction. In infants and younger children with associated severe obstructive sleep apnea, advancement by distraction osteogenesis of the midface in Le Fort III maxillary osteotomy will be initially indicated to obviate tracheostomy improving the upper airway obstruction.     

颌骨前移治疗阻塞性睡眠呼吸暂停低通气综合征的CT研究

目的探讨阻塞性睡眠呼吸暂停低通气综合征（obstructive sleep apnea hypopnea syndrome，OSAHS）外科治疗的解剖形态学基础。方法小下颌畸形伴OSAHS患者共9例，平均年龄28．6岁（18—39岁），所有患者均经正颌外科和（或）颌骨牵引成骨治疗，手术前、后行多道睡眠监测仪监测及螺旋CT扫描，分别评价手术疗效并比较患者上气道三维结构的变化。结果9例患者经外科治疗后均达临床治愈标准；手术后上气道的矢状径、横径、横截面积及容积均较术前明显增加，其中矢状径的增加最显著，变化主要发生在口咽及舌咽，喉咽变化不明显。结论正颌外科及颌骨牵引成骨是使腭咽及舌咽的矢状径增加从而有效治疗小下颌畸伴OSAHS。     

Distraction osteogenesis for management of obstructive sleep apnoea in temporomandibular joint ankylosis patients before the release of joint

AimTo evaluate the effects of distraction osteogenesis in management of obstructive sleep apnoea patients secondary to temporomandibular joints ankylosis.MethodsFifteen patients were included in study. Preoperatively the patients were worked up for polysomnography and CT scans. Only those patients with Apnoea–hypopnoea index >15 events/h denoting moderate to severe obstructive sleep apnoea were included in the study. Distraction osteogenesis was followed with 5 days latency period in adult patients and 0 days for children. Rate of distraction was 1 mm/day for adults and 2 mm/day for children till the mandibular incisors were in reverse overjet. After 3 months post distraction assessment was done using polysomnography and CT scan.TMJ ankylosis was released by doing gap arthroplasty after distraction osteogenesis.ResultsPost distraction improvement was seen in clinical features of OSA like daytime sleepiness and snoring. Epworth sleepiness scale improved from a mean of 10.25 to 2.25. Polysomnographic analysis also showed improvement in all cases with apnoea–hypopnoea index from 57.03 to 6.67 per hour. Lowest oxygen saturation improved from 64.47% to 81.20% and average minimum oxygen saturation improved from 92.17% to 98.19%. Body mass index improved from a mean of 18.26 to 21.39 kg/m².ConclusionDistraction osteogenesis is a stable and beneficial treatment option for temporomandibular joint ankylosis patients with obstructive sleep apnoea.     

Clinical success of mandibular distraction for obstructive sleep apnea resulting from micrognathia in 10 consecutive Japanese young children

In recent years, obstructive sleep apnea has gained attention as one of the causes of sudden death in young children. There have been some reports, mainly from the United States and Europe, that mandibular distraction osteogenesis is effective as a treatment for obstructive sleep apnea syndrome caused by micrognathia in young children. However, there has not been any report yet in Japan. In this study, we performed mandibular distraction osteogenesis using internal devices in 10 young children with obstructive sleep apnea. To enable distraction to be performed smoothly without any difficulties, we modified a surgical procedure by adding an osteotomy of the coronoid process to a vertical ramus osteotomy. Postoperative evaluations using cephalograms and polysomnography were performed, and great improvements were observed. As a result, all patients either avoided or were weaned from tracheostomy, and very good results were obtained similar to those in reports from the United States and Europe. We report our experience in Japan.     

The sequential treatment of temporomandibular joint ankylosis with secondary deformities by distraction osteogenesis and arthroplasty or TMJ reconstruction

The purpose of this study was to evaluate the sequential treatment of patients with temporomandibular joint (TMJ) ankylosis and secondary deformities by distraction osteogenesis and subsequent arthroplasty or TMJ reconstruction. This study included 40 patients treated at a stomatological hospital in China; they ranged in age from 9 to 53 years (mean age 24.5 years). Ten of these patients were diagnosed with unilateral TMJ ankylosis and 30 with bilateral TMJ ankylosis. Twenty-seven patients also presented obstructive sleep apnoea–hypopnoea syndrome (OSAHS). All patients underwent distraction osteogenesis as the initial surgery, followed by arthroplasty or TMJ reconstruction. Some patients underwent orthognathic surgery to improve occlusion and face shape along with or after arthroplasty or TMJ reconstruction. The therapeutic effects were evaluated in terms of the improvements in maximum inter-incisal opening (MIO), appearance, and respiratory function. After the completion of treatment, all patients showed improvements in MIO and appearance, and the symptom of snoring disappeared. The airway space was significantly increased. Patient follow-up ranged from 6 to 85 months (mean 28.3 months), and four patients experienced relapse. This study suggests that treating TMJ ankylosis with secondary deformities by distraction osteogenesis as the initial surgery and arthroplasty or TMJ reconstruction as the second-stage treatment may achieve favourable outcomes, especially for patients with OSAHS; however, some patients may require orthognathic surgery.     

Facial nerve paralysis: a complication of distraction osteogenesis of the mandibular ramus in the treatment of temporomandibular joint ankylosis

Distraction osteogenesis is a useful technique in temporomandibular joint reconstruction after gap arthroplasty for ankylosis. We report a case of unilateral facial nerve paralysis during the distraction phase of treatment in a patient with temporomandibular joint ankylosis who was treated with gap arthroplasty and distraction osteogenesis. The clinical course is described and discussed.     

内置式下颌骨牵引成骨术的早期并发症及防治

目的 总结内置式下颌骨牵引成骨术(DO)术中和术后早期并发症，探讨其有效防治方法。方法 对1997年11月～2002年12月间应用DO治疗的48例(83侧)下颌骨畸形或缺损患者进行分析。其中颞下颌关节强直伴小颌畸形双侧13例、单侧9例，下颌骨发育不足或小颌畸形14例，第一、二鳃弓综合征单侧5例、双侧1例，爆炸伤或肿瘤术后缺损畸形5例，Treacher Colins综合征1例，伴睡眠呼吸暂停综合征(OSAHS)者19例。所有病例均采用口内或(联合)口外切口并应用内置式牵引器。总结自施行手术开始至牵引完成期间的并发症及处理措施。结果 6例患者出现术中或术后早期并发症，发生率为12．5％，其中牵引机械装置故障2例，骨皮质切开术不彻底1例，早期感染1例，前牙严重开He1例，牵引早期疼痛剧烈1例，积极处理后均达到预期治疗目的。结论 减少DO术中及术后早期并发症的关键在于充分理解下颌骨牵引成骨术的机理，熟悉掌握下颌骨及邻近解剖结构，熟练操作规范，充分的术前准备和术后护理尤为重要。