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近年来,随着MR技术的发展,一些功能成像技术,如扩散加权成像、动态增强MRI和MR波谱技术也越来越多地应用于前列腺研究。通过其对组织生理、病理和血供改变的观察,获悉活体器官功能状态,为前列腺癌早期发现,正确的诊断、分期和鉴别诊断提供了依据。 相似文献
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目的 探讨3.0T磁共振动态增强定量参数分析联合DWI对前列腺癌诊断的临床价值。方法 选取我院接受过治疗的80例前列腺癌患者,然后将他们平均分为两组:观察组和对照组,每组各40例。对照组采用3.0T磁共振动态增强定量参数分析诊治,观察组采用3.0T磁共振动态增强定量参数分析联合DWI诊治。对观察组和对照组的前列腺癌患者检查结果、诊断效能、患者满意度等情况进行比较分析。结果 观察组的病理检查结果优于对照组。观察组的敏感度、特异度、准确度均优于对照组。观察组的前列腺癌患者满意度高于对照组。结论 3.0T磁共振动态增强定量参数分析联合DWI在前列腺癌的诊断中具有重要的应用价值,便于临床早期诊断。 相似文献
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3.0 T磁共振扩散加权成像在直肠癌诊断中的价值 总被引:1,自引:0,他引:1
目的 探讨MR扩散加权成像(DWI)在直肠癌诊断中的临床应用价值.资料与方法对50例直肠癌患者和17名无直肠病变的自愿者行盆腔T2WI和DWI,由两名放射诊断医师采用肓法随机进行MRI阅片后对比分析单纯T2WI与T2WI结合DWI对直肠癌诊断的特异性和敏感性差异,并对直肠癌和正常肠壁的表观扩散系数(ADC)值进行定量分析.结果两名医师单纯应用T2WI与T2WI结合DWI检出直肠癌的ROC曲线下面积(Az)值分别为0.873与0.978(P<0.05)、0.905与0.986(P<0.05).Kappa一致性检验表明两名医师具有良好的一致性(Kappa值分别为0.860和0.828,P<0.05).直肠癌和其癌周正常肠壁ADC值的平均值±标准差分别为(0.93±0.14)×10-3 mm2/s、(1.40±0.17)×10-3 mm2/s,直肠癌与正常肠壁的ADC值间差异有统计学意义(t=17.43,P<0.01).结论 3.0 T MR DWI能较直观地显示直肠癌,其作为常规T2WI的补充检查序列可以明显提高对直肠癌的检出率. 相似文献
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目的 探讨1.5T MR 超高b值扩散加权成像(DWI)对前列腺癌(PCa)的诊断价值.方法 收集分析行常规MRI和DWI(b值为400、800、1 400 s/mm2)扫描,并经临床病理证实的PCa 12例,前列腺增生(BPH)17例,分别测量各b值DWI上感兴趣区(ROI)的信号强度,对ROI的可视化程度进行分级,比较其间是否存在差异.结果 超高b值与高b值DWI PCa病灶的信号强度差异有统计学意义(χ2=220.957,P=0.000<0.05);b值越高,DWI上PCa癌灶亮度对比越高,可视化程度差异有统计学意义(χ2=11.378,P=0.003<0.05).超高b值DWI上PCa癌灶与BPH和正常外周带信号强度有统计学意义(χ2=25.913,P=0.000<0.05),超高b值DWI PCa病灶亮度主要是亮和灰亮(占71.4%),BPH和正常外周带的亮度以暗和灰暗为主(BPH组占63.0%,正常外周带组占73.3%);可视化程度差异都有统计学意义(Z=-6.908、-6.110,P值均为0.000<0.017).b=1 400 s/mm2的DWI信号强度和可视化程度诊断效能最高.结论 1.5T MR超高b值DWI能提高PCa癌灶的显示率,易于观察和诊断. 相似文献
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目的探讨MRI扩散加权成像(DWI)和ADC图在前列腺癌及其邻近器官侵犯诊断与鉴别诊断中的价值。方法回顾性分析经穿刺活检或手术病理证实的前列腺癌30例。所有患者均进行MRI常规扫描和DWI扫描,DWI序列取b值为0、100、800及200、1000两组分别扫描,分析DWI表现和表观扩散系数(ADC)图,并测量癌肿区及周围侵犯区的ADC值。结果前列腺癌病灶和邻近组织侵犯的病灶在两组扫描中5个序列DWI图上均呈高信号,ADC图呈低信号。所有病例的ADC值均低于(897.4±67.5)×10-6。结论 DWI成像检查在前列腺癌及其周围侵犯的诊断中具有特征性表现,在临床上有较高的应用价值。 相似文献
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目的 探讨磁共振弥散加权成像(DWI)、T2加权像(T2WI)及动态增强(DCE)联合应用对前列腺癌的诊断价值.方法 100例前列腺疾病中前列腺癌49例和非癌病例51例(包括46例前列腺增生、3例外周带炎症及2例前列腺结核).所有病例在常规MR检查基础上加扫DCE及DWI序列,DWI的b值为800 s/mm2.比较T2WI、DCE、DWI及三者联合诊断前列腺癌的敏感性;统计分析前列腺组织与非癌组织的ADC值是否存在差异.结果 在DWI图像上,前列腺癌多呈明显高信号,6例局限于中央带前列腺癌得到正确诊断.前列腺癌组织的平均ADC值为(0.96±0.22)×10-3mm2/s,前列腺增生组织的平均ADC值为(1.56±0.23)×10-3mm2/s,两者之间有统计学差异(P=0.001),但ADC值有小部分重叠.T2WI、DCE、DWI及三者联合诊断前列腺癌的敏感性分别为85.7%、87.8%、93.9%、100%.结论 T2WI、DCE及DWI三者联合应用可以弥补各自的缺点,提高前列腺癌诊断的敏感性. 相似文献
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前列腺癌是欧美男性发病率最高的恶性肿瘤,其病死率仅次于肺癌。近年来,随着我国人口老龄化的加速和饮食结构的变化,前列腺癌的发病率呈明显上升趋势。因此,对前列腺病变早期定性有利于病变的早期检出和病死率的降低,还有利于提高预后。MRI检查在前列腺病变的早期定性中具有明显优势。就MRI-T2WI、动态增强(DCE)MRI、扩散加权成像(DWI)、磁共振波谱(MRS)及其联合应用在前列腺良恶性病变鉴别中的作用,MRI各参数与前列腺特异性抗原(PSA)的相关性以及成像序列的选择予以综述。 相似文献
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目前,对前列腺癌的诊断方法主要包括酸性磷酸酶的放射免疫测定、前列腺液的乳酸脱氢酶的测定、经直肠的超声显像、CT检查、前列腺穿刺针改进、磁共振DWI结合 相似文献
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磁共振常规成像及DWI对脑膜瘤的诊断价值 总被引:1,自引:0,他引:1
目的:比较磁共振常规成像序列(T1WI、T2WI及FLAIR)与DWI对脑膜瘤的检出率,探讨其鉴别病理亚型及良恶性的价值。方法:回顾性分析70例经手术病理证实的脑膜瘤患者的MRI图像,计算不同序列对脑膜瘤的检出率;测量并比较不同病理亚型、不同病理分级的肿瘤实质的平均ADC值和相对ADC值(rADC值)。结果:在T2WI上出现低信号的多是纤维型、过渡型和砂粒体型,出现高信号的多是脑膜上皮型和血管瘤型。在各个序列中,以DWI对脑膜瘤病变的检出率最高(87.1%),T2WI次之(74.3%),T1WI最低(38.6%)。恶性脑膜瘤的囊变发生率(67%)明显高于良性脑膜瘤(22%)。良性组各亚型间、良恶性两组间平均ADC值及rADC值差异均无统计学意义(P>0.05)。结论:DWI可提高对脑膜瘤的检出率,但单独根据ADC值并不能鉴别脑膜瘤的亚型及良恶性。DWI结合常规MRI表现对脑膜瘤亚型及良恶性的鉴别有一定意义。 相似文献
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目的对直肠癌患者行3.0T磁共振不同b值的扩散加权成像,选取显示直肠癌的最适b值。方法对75例术后确诊的直肠癌患者分别行b=800、1 000、1 200、1 500 s/mm2与1 800 s/mm2五组扩散加权成像,分别将不同b值的各组间肿瘤本身SNR、肿瘤与肌肉的对比噪声比CNR和肿瘤与脂肪的CNR作比较。结果 SNR、CNR值均呈正态分布,b值为1 200 s/mm2与1 500 s/mm2时SNR、CNR差异无显著性意义(P>0.05),但低于b值1 200 s/mm2及高于1 500 s/mm2的差异均有显著性意义(P<0.05)。结论超高场3.0T磁共振扩散加权成像诊断直肠癌的b值选取1 200 s/mm2和1 500 s/mm2较合适。 相似文献
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Kyung A Kang Young Kon Kim EunJu Kim Woo Kyoung Jeong Dongil Choi Won Jae Lee Sin-Ho Jung Sun-Young Baek 《Korean journal of radiology》2015,16(5):1038-1046
Objective
To assess the value of applying MultiVane to liver T2-weighted imaging (T2WI) compared with conventional T2WIs with emphasis on detection of focal liver lesions.Materials and Methods
Seventy-eight patients (43 men and 35 women) with 86 hepatic lesions and 20 pancreatico-biliary diseases underwent MRI including T2WIs acquired using breath-hold (BH), respiratory-triggered (RT), and MultiVane technique at 3T. Two reviewers evaluated each T2WI with respect to artefacts, organ sharpness, and conspicuity of intrahepatic vessels, hilar duct, and main lesion using five-point scales, and made pairwise comparisons between T2WI sequences for these categories. Diagnostic accuracy (Az) and sensitivity for hepatic lesion detection were evaluated using alternative free-response receiver operating characteristic analysis.Results
MultiVane T2WI was significantly better than BH-T2WI or RT-T2WI for organ sharpness and conspicuity of intrahepatic vessels and main lesion in both separate reviews and pairwise comparisons (p < 0.001). With regard to motion artefacts, MultiVane T2WI or BH-T2WI was better than RT-T2WI (p < 0.001). Conspicuity of hilar duct was better with BH-T2WI than with MultiVane T2WI (p = 0.030) or RT-T2WI (p < 0.001). For detection of 86 hepatic lesions, sensitivity (mean, 97.7%) of MultiVane T2WI was significantly higher than that of BH-T2WI (mean, 89.5%) (p = 0.008) or RT-T2WI (mean, 84.9%) (p = 0.001).Conclusion
Applying the MultiVane technique to T2WI of the liver is a promising approach to improving image quality that results in increased detection of focal liver lesions compared with conventional T2WI. 相似文献13.
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Ai-Jun Ren Yong Guo Shu-Ping Tian Li-Jing Shi Min-Hua Huang 《Korean journal of radiology》2012,13(1):44-52
Objective
To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine.Materials and Methods
Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student''s t test and Wilcoxon''s signed rank test.Results
Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE.Conclusion
As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T. 相似文献15.
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目的 探讨3.0T常规MRI T2 WI抑脂序列联合三维超长回波链采集FSE(3D CUBE) T2 WI抑脂序列对肛瘘患者的临床诊断价值.方法 回顾性分析33例经手术证实的肛瘘患者术前常规MRI T2WI抑脂序列及3DCUBE T2 WI抑脂序列资料.比较两种技术评价肛瘘分型、瘘管支数、内口总数、外口数目、肛周脓肿和瘘管整体的优势,并与手术结果相对照.结果 手术发现33例肛瘘中,经括约肌瘘14例,括约肌间瘘10例,括约肌外瘘8例,括约肌上瘘1例.瘘管支数52个,内口45个,外口48个,肛周脓肿30个.常规MRI T2WI抑脂序列与常规MRI T2WI抑脂序列联合3D CBUE T2WI抑脂序列肛瘘的分型准确率分别为78.8% (26/33)和87.9% (29/33),差别无统计学意义(JP>0.05);瘘管支数显示率分别为71.2%(37/52)和90.4% (47/52),内口总数显示率分别为71.1% (32/45)和91.1% (41/45),差异具有统计学意义(P<0.05).两种技术显示外口数目和肛周脓肿与手术结果一致.结论 常规MRI T2WI抑脂序列联合3D CUBE T2WI抑脂序列能准确显示瘘管支数、内口总数和瘘管整体,优于常规MRI T2 WI抑脂序列,为临床术前提供更详尽的影像解剖信息. 相似文献
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目的 探讨分别应用T2WI、DWI以及综合应用2种成像序列对前列腺移行区良恶性结节的鉴别诊断价值.方法 收集2006-08-2010-04在本院3.0T磁共振行常规及DWI扫描(b值分别为0 s/mm2和800 s/mm2)的前列腺疾病患者,其中70例前列腺移行区见到结节样异常信号者被纳入本研究,本组患者后来均行超声引导下经直肠前列腺穿刺活检术.分析良恶性结节的MRI表现,比较其ADC值.采用5分制评分,将所得结果与病理结果对照,用SPSS11.5分别做受试者工作特征曲线(ROC),分析比较各组方法诊断的敏感度和特异度.结果 病理证实54例患者为前列腺移行区良性结节,16例为移行区前列腺癌(prostate cancer,PCa),良性和恶性结节的ADC值分别为(1.352±0.088 5)×10-3 mm2/s和(0.931±0.079 5)×10-3 mm2/s,恶性结节的ADC值明显低于良性结节(P<0.05).联合DWI和T2WI 2种成像序列鉴别前列腺移行区良恶性结节的ROC曲线下面积(AUC)最大(0.993,95%CI:0.935~0.995),其与单独应用T2WI 的AUC之间的差异有统计学意义(Z=2.093,P<0.05),但是与单独应用DWI的AUC之间的差异无统计学意义(Z=0.905,P=0.365);T2WI鉴别前列腺移行区良恶性结节的AUC低于DWI的,但两者之间的差异无统计学意义(Z=1.629,P=0.103),2种序列结合鉴别前列腺移行区良恶性结节的特异度和敏感度最高.结论 前列腺移行区恶性结节的ADC值明显低于良性结节;联合应用DWI和T2WI鉴别诊断良恶性结节的特异度和敏感度最高. 相似文献
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目的探讨3.0T磁共振肝脏快速容积采集技术(LAVA)动态增强判断子宫内膜癌肌层浸润深度的应用价值。资料与方法回顾性分析52例子宫内膜癌的T2WI和LAVA动态增强图像,以手术病理结果为标准,计算两种序列诊断子宫内膜癌肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性。结果 T2WI判断内膜癌肌层浸润及深肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为84.4%、71.4%、95.0%、41.7%、82.7%和63.6%、82.9%、50.0%、89.5%、78.8%。LAVA动态增强判断内膜癌肌层浸润及深肌层浸润敏感性、特异性、阳性预测值、阴性预测值和准确性分别为93.3%、85.7%、97.7%、66.7%、92.3%和90.9%、95.1%、83.3%、97.5%、94.2%。LAVA动态增强判断子宫内膜癌深肌层受侵的准确性高于T2WI诊断的准确性,差异有统计学意义(P<0.05)。结论 3.0T磁共振LAVA动态增强扫描有助于提高子宫内膜癌肌层浸润术前诊断的准确性。 相似文献
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Heesakkers RA Fütterer JJ Hövels AM van den Bosch HC Scheenen TW Hoogeveen YL Barentsz JO 《Radiology》2006,239(2):481-487
PURPOSE: To prospectively evaluate the feasibility of ferumoxtran-10-enhanced magnetic resonance (MR) imaging at high magnetic field strength (3.0 T) and to compare image quality between 1.5- and 3.0-T MR imaging in terms of lymph node detection in patients with prostate cancer. MATERIALS AND METHODS: This study was institutional review board approved, and all patients gave written informed consent. Forty-eight consecutive patients aged 51-79 years (mean, 65.5 years) with prostate cancer were enrolled. T2*-weighted 1.5- and 3.0-T MR images of the pelvis were acquired in a sagittal plane parallel to the psoas muscle 24 hours after ferumoxtran-10 administration. A pelvic and body phased-array coil was used and yielded an in-plane resolution of 0.56 x 0.56 x 3.00 mm at 1.5 T and 0.50 x 0.50 x 2.50 mm at 3.0 T. All images were evaluated by three readers for total image quality, lymph node border delineation, muscle-fat contrast, and vessel-fat contrast. Statistical significance was calculated by using the Mann-Whitney U test. Subsequently, the general linear mixed model was used to estimate the contributions of three factors-patient, reader, and technique-to the variability of the imaging results. RESULTS: Significantly (P < .05) better muscle-fat contrast, vessel-fat contrast, lymph node border delineation, and total image quality were observed at 3.0-T MR imaging. The general linear mixed model revealed that the variability of all results could be attributed to the use of 3.0-T imaging. CONCLUSION: Ferumoxtran-10-enhanced MR imaging can be performed at high magnetic field strengths and result in improved image quality, which may lead to improved detection of small positive lymph nodes. 相似文献