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1.
近年来,随着MR技术的发展,一些功能成像技术,如扩散加权成像、动态增强MRI和MR波谱技术也越来越多地应用于前列腺研究。通过其对组织生理、病理和血供改变的观察,获悉活体器官功能状态,为前列腺癌早期发现,正确的诊断、分期和鉴别诊断提供了依据。  相似文献   

2.
目的 探讨3.0T磁共振动态增强定量参数分析联合DWI对前列腺癌诊断的临床价值。方法 选取我院接受过治疗的80例前列腺癌患者,然后将他们平均分为两组:观察组和对照组,每组各40例。对照组采用3.0T磁共振动态增强定量参数分析诊治,观察组采用3.0T磁共振动态增强定量参数分析联合DWI诊治。对观察组和对照组的前列腺癌患者检查结果、诊断效能、患者满意度等情况进行比较分析。结果 观察组的病理检查结果优于对照组。观察组的敏感度、特异度、准确度均优于对照组。观察组的前列腺癌患者满意度高于对照组。结论 3.0T磁共振动态增强定量参数分析联合DWI在前列腺癌的诊断中具有重要的应用价值,便于临床早期诊断。  相似文献   

3.
3.0 T磁共振扩散加权成像在直肠癌诊断中的价值   总被引:1,自引:0,他引:1  
目的 探讨MR扩散加权成像(DWI)在直肠癌诊断中的临床应用价值.资料与方法对50例直肠癌患者和17名无直肠病变的自愿者行盆腔T2WI和DWI,由两名放射诊断医师采用肓法随机进行MRI阅片后对比分析单纯T2WI与T2WI结合DWI对直肠癌诊断的特异性和敏感性差异,并对直肠癌和正常肠壁的表观扩散系数(ADC)值进行定量分析.结果两名医师单纯应用T2WI与T2WI结合DWI检出直肠癌的ROC曲线下面积(Az)值分别为0.873与0.978(P<0.05)、0.905与0.986(P<0.05).Kappa一致性检验表明两名医师具有良好的一致性(Kappa值分别为0.860和0.828,P<0.05).直肠癌和其癌周正常肠壁ADC值的平均值±标准差分别为(0.93±0.14)×10-3 mm2/s、(1.40±0.17)×10-3 mm2/s,直肠癌与正常肠壁的ADC值间差异有统计学意义(t=17.43,P<0.01).结论 3.0 T MR DWI能较直观地显示直肠癌,其作为常规T2WI的补充检查序列可以明显提高对直肠癌的检出率.  相似文献   

4.
目的 探讨1.5T MR 超高b值扩散加权成像(DWI)对前列腺癌(PCa)的诊断价值.方法 收集分析行常规MRI和DWI(b值为400、800、1 400 s/mm2)扫描,并经临床病理证实的PCa 12例,前列腺增生(BPH)17例,分别测量各b值DWI上感兴趣区(ROI)的信号强度,对ROI的可视化程度进行分级,比较其间是否存在差异.结果 超高b值与高b值DWI PCa病灶的信号强度差异有统计学意义(χ2=220.957,P=0.000<0.05);b值越高,DWI上PCa癌灶亮度对比越高,可视化程度差异有统计学意义(χ2=11.378,P=0.003<0.05).超高b值DWI上PCa癌灶与BPH和正常外周带信号强度有统计学意义(χ2=25.913,P=0.000<0.05),超高b值DWI PCa病灶亮度主要是亮和灰亮(占71.4%),BPH和正常外周带的亮度以暗和灰暗为主(BPH组占63.0%,正常外周带组占73.3%);可视化程度差异都有统计学意义(Z=-6.908、-6.110,P值均为0.000<0.017).b=1 400 s/mm2的DWI信号强度和可视化程度诊断效能最高.结论 1.5T MR超高b值DWI能提高PCa癌灶的显示率,易于观察和诊断.  相似文献   

5.
目的探讨MRI扩散加权成像(DWI)和ADC图在前列腺癌及其邻近器官侵犯诊断与鉴别诊断中的价值。方法回顾性分析经穿刺活检或手术病理证实的前列腺癌30例。所有患者均进行MRI常规扫描和DWI扫描,DWI序列取b值为0、100、800及200、1000两组分别扫描,分析DWI表现和表观扩散系数(ADC)图,并测量癌肿区及周围侵犯区的ADC值。结果前列腺癌病灶和邻近组织侵犯的病灶在两组扫描中5个序列DWI图上均呈高信号,ADC图呈低信号。所有病例的ADC值均低于(897.4±67.5)×10-6。结论 DWI成像检查在前列腺癌及其周围侵犯的诊断中具有特征性表现,在临床上有较高的应用价值。  相似文献   

6.
目的 探讨磁共振弥散加权成像(DWI)、T2加权像(T2WI)及动态增强(DCE)联合应用对前列腺癌的诊断价值.方法 100例前列腺疾病中前列腺癌49例和非癌病例51例(包括46例前列腺增生、3例外周带炎症及2例前列腺结核).所有病例在常规MR检查基础上加扫DCE及DWI序列,DWI的b值为800 s/mm2.比较T2WI、DCE、DWI及三者联合诊断前列腺癌的敏感性;统计分析前列腺组织与非癌组织的ADC值是否存在差异.结果 在DWI图像上,前列腺癌多呈明显高信号,6例局限于中央带前列腺癌得到正确诊断.前列腺癌组织的平均ADC值为(0.96±0.22)×10-3mm2/s,前列腺增生组织的平均ADC值为(1.56±0.23)×10-3mm2/s,两者之间有统计学差异(P=0.001),但ADC值有小部分重叠.T2WI、DCE、DWI及三者联合诊断前列腺癌的敏感性分别为85.7%、87.8%、93.9%、100%.结论 T2WI、DCE及DWI三者联合应用可以弥补各自的缺点,提高前列腺癌诊断的敏感性.  相似文献   

7.
前列腺癌是欧美男性发病率最高的恶性肿瘤,其病死率仅次于肺癌。近年来,随着我国人口老龄化的加速和饮食结构的变化,前列腺癌的发病率呈明显上升趋势。因此,对前列腺病变早期定性有利于病变的早期检出和病死率的降低,还有利于提高预后。MRI检查在前列腺病变的早期定性中具有明显优势。就MRI-T2WI、动态增强(DCE)MRI、扩散加权成像(DWI)、磁共振波谱(MRS)及其联合应用在前列腺良恶性病变鉴别中的作用,MRI各参数与前列腺特异性抗原(PSA)的相关性以及成像序列的选择予以综述。  相似文献   

8.
目前,对前列腺癌的诊断方法主要包括酸性磷酸酶的放射免疫测定、前列腺液的乳酸脱氢酶的测定、经直肠的超声显像、CT检查、前列腺穿刺针改进、磁共振DWI结合  相似文献   

9.
磁共振常规成像及DWI对脑膜瘤的诊断价值   总被引:1,自引:0,他引:1  
目的:比较磁共振常规成像序列(T1WI、T2WI及FLAIR)与DWI对脑膜瘤的检出率,探讨其鉴别病理亚型及良恶性的价值。方法:回顾性分析70例经手术病理证实的脑膜瘤患者的MRI图像,计算不同序列对脑膜瘤的检出率;测量并比较不同病理亚型、不同病理分级的肿瘤实质的平均ADC值和相对ADC值(rADC值)。结果:在T2WI上出现低信号的多是纤维型、过渡型和砂粒体型,出现高信号的多是脑膜上皮型和血管瘤型。在各个序列中,以DWI对脑膜瘤病变的检出率最高(87.1%),T2WI次之(74.3%),T1WI最低(38.6%)。恶性脑膜瘤的囊变发生率(67%)明显高于良性脑膜瘤(22%)。良性组各亚型间、良恶性两组间平均ADC值及rADC值差异均无统计学意义(P>0.05)。结论:DWI可提高对脑膜瘤的检出率,但单独根据ADC值并不能鉴别脑膜瘤的亚型及良恶性。DWI结合常规MRI表现对脑膜瘤亚型及良恶性的鉴别有一定意义。  相似文献   

10.
目的对直肠癌患者行3.0T磁共振不同b值的扩散加权成像,选取显示直肠癌的最适b值。方法对75例术后确诊的直肠癌患者分别行b=800、1 000、1 200、1 500 s/mm2与1 800 s/mm2五组扩散加权成像,分别将不同b值的各组间肿瘤本身SNR、肿瘤与肌肉的对比噪声比CNR和肿瘤与脂肪的CNR作比较。结果 SNR、CNR值均呈正态分布,b值为1 200 s/mm2与1 500 s/mm2时SNR、CNR差异无显著性意义(P>0.05),但低于b值1 200 s/mm2及高于1 500 s/mm2的差异均有显著性意义(P<0.05)。结论超高场3.0T磁共振扩散加权成像诊断直肠癌的b值选取1 200 s/mm2和1 500 s/mm2较合适。  相似文献   

11.
目的分析膀胱受累的前列腺癌的MRI表现,评价MRI对前列腺癌的定性诊断价值,避免伴膀胱受累的前列腺癌误诊为膀胱肿瘤。资料与方法回顾性分析15例行MRI检查前曾误诊为膀胱癌的前列腺癌患者的临床及MRI资料。结果 15例误诊病变MRI均明确诊断为前列腺癌,其中C期10例,D期5例。结论 MRI是诊断前列腺癌良好的影像学方法,特别是当病变累及膀胱时,可很好地避免误诊为膀胱肿瘤,再结合其他检查方法,可提高前列腺癌的诊断准确率。  相似文献   

12.

Objective

To assess the value of applying MultiVane to liver T2-weighted imaging (T2WI) compared with conventional T2WIs with emphasis on detection of focal liver lesions.

Materials and Methods

Seventy-eight patients (43 men and 35 women) with 86 hepatic lesions and 20 pancreatico-biliary diseases underwent MRI including T2WIs acquired using breath-hold (BH), respiratory-triggered (RT), and MultiVane technique at 3T. Two reviewers evaluated each T2WI with respect to artefacts, organ sharpness, and conspicuity of intrahepatic vessels, hilar duct, and main lesion using five-point scales, and made pairwise comparisons between T2WI sequences for these categories. Diagnostic accuracy (Az) and sensitivity for hepatic lesion detection were evaluated using alternative free-response receiver operating characteristic analysis.

Results

MultiVane T2WI was significantly better than BH-T2WI or RT-T2WI for organ sharpness and conspicuity of intrahepatic vessels and main lesion in both separate reviews and pairwise comparisons (p < 0.001). With regard to motion artefacts, MultiVane T2WI or BH-T2WI was better than RT-T2WI (p < 0.001). Conspicuity of hilar duct was better with BH-T2WI than with MultiVane T2WI (p = 0.030) or RT-T2WI (p < 0.001). For detection of 86 hepatic lesions, sensitivity (mean, 97.7%) of MultiVane T2WI was significantly higher than that of BH-T2WI (mean, 89.5%) (p = 0.008) or RT-T2WI (mean, 84.9%) (p = 0.001).

Conclusion

Applying the MultiVane technique to T2WI of the liver is a promising approach to improving image quality that results in increased detection of focal liver lesions compared with conventional T2WI.  相似文献   

13.
14.

Objective

To compare the iterative decomposition of water and fat with echo asymmetry and the least-squares estimation (IDEAL) method with a fat-saturated T2-weighted (T2W) fast recovery fast spin-echo (FRFSE) imaging of the spine.

Materials and Methods

Images acquired at 3.0 Tesla (T) in 35 patients with different spine lesions using fat-saturated T2W FRFSE imaging were compared with T2W IDEAL FRFSE images. Signal-to-noise ratio (SNR)-efficiencies measurements were made in the vertebral bodies and spinal cord in the mid-sagittal plane or nearest to the mid-sagittal plane. Images were scored with the consensus of two experienced radiologists on a four-point grading scale for fat suppression and overall image quality. Statistical analysis of SNR-efficiency, fat suppression and image quality scores was performed with a paired Student''s t test and Wilcoxon''s signed rank test.

Results

Signal-to-noise ratio-efficiency for both vertebral body and spinal cord was higher with T2W IDEAL FRFSE imaging (p < 0.05) than with T2W FRFSE imaging. T2W IDEAL FRFSE demonstrated superior fat suppression (p < 0.01) and image quality (p < 0.01) compared to fat-saturated T2W FRFSE.

Conclusion

As compared with fat-saturated T2W FRFSE, IDEAL can provide a higher image quality, higher SNR-efficiency, and consistent, robust and uniform fat suppression. T2W IDEAL FRFSE is a promising technique for MR imaging of the spine at 3.0T.  相似文献   

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16.
目的 探讨3.0T常规MRI T2 WI抑脂序列联合三维超长回波链采集FSE(3D CUBE) T2 WI抑脂序列对肛瘘患者的临床诊断价值.方法 回顾性分析33例经手术证实的肛瘘患者术前常规MRI T2WI抑脂序列及3DCUBE T2 WI抑脂序列资料.比较两种技术评价肛瘘分型、瘘管支数、内口总数、外口数目、肛周脓肿和瘘管整体的优势,并与手术结果相对照.结果 手术发现33例肛瘘中,经括约肌瘘14例,括约肌间瘘10例,括约肌外瘘8例,括约肌上瘘1例.瘘管支数52个,内口45个,外口48个,肛周脓肿30个.常规MRI T2WI抑脂序列与常规MRI T2WI抑脂序列联合3D CBUE T2WI抑脂序列肛瘘的分型准确率分别为78.8% (26/33)和87.9% (29/33),差别无统计学意义(JP>0.05);瘘管支数显示率分别为71.2%(37/52)和90.4% (47/52),内口总数显示率分别为71.1% (32/45)和91.1% (41/45),差异具有统计学意义(P<0.05).两种技术显示外口数目和肛周脓肿与手术结果一致.结论 常规MRI T2WI抑脂序列联合3D CUBE T2WI抑脂序列能准确显示瘘管支数、内口总数和瘘管整体,优于常规MRI T2 WI抑脂序列,为临床术前提供更详尽的影像解剖信息.  相似文献   

17.
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目的 探讨分别应用T2WI、DWI以及综合应用2种成像序列对前列腺移行区良恶性结节的鉴别诊断价值.方法 收集2006-08-2010-04在本院3.0T磁共振行常规及DWI扫描(b值分别为0 s/mm2和800 s/mm2)的前列腺疾病患者,其中70例前列腺移行区见到结节样异常信号者被纳入本研究,本组患者后来均行超声引导下经直肠前列腺穿刺活检术.分析良恶性结节的MRI表现,比较其ADC值.采用5分制评分,将所得结果与病理结果对照,用SPSS11.5分别做受试者工作特征曲线(ROC),分析比较各组方法诊断的敏感度和特异度.结果 病理证实54例患者为前列腺移行区良性结节,16例为移行区前列腺癌(prostate cancer,PCa),良性和恶性结节的ADC值分别为(1.352±0.088 5)×10-3 mm2/s和(0.931±0.079 5)×10-3 mm2/s,恶性结节的ADC值明显低于良性结节(P<0.05).联合DWI和T2WI 2种成像序列鉴别前列腺移行区良恶性结节的ROC曲线下面积(AUC)最大(0.993,95%CI:0.935~0.995),其与单独应用T2WI 的AUC之间的差异有统计学意义(Z=2.093,P<0.05),但是与单独应用DWI的AUC之间的差异无统计学意义(Z=0.905,P=0.365);T2WI鉴别前列腺移行区良恶性结节的AUC低于DWI的,但两者之间的差异无统计学意义(Z=1.629,P=0.103),2种序列结合鉴别前列腺移行区良恶性结节的特异度和敏感度最高.结论 前列腺移行区恶性结节的ADC值明显低于良性结节;联合应用DWI和T2WI鉴别诊断良恶性结节的特异度和敏感度最高.  相似文献   

19.
目的探讨3.0T磁共振肝脏快速容积采集技术(LAVA)动态增强判断子宫内膜癌肌层浸润深度的应用价值。资料与方法回顾性分析52例子宫内膜癌的T2WI和LAVA动态增强图像,以手术病理结果为标准,计算两种序列诊断子宫内膜癌肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性。结果 T2WI判断内膜癌肌层浸润及深肌层浸润的敏感性、特异性、阳性预测值、阴性预测值和准确性分别为84.4%、71.4%、95.0%、41.7%、82.7%和63.6%、82.9%、50.0%、89.5%、78.8%。LAVA动态增强判断内膜癌肌层浸润及深肌层浸润敏感性、特异性、阳性预测值、阴性预测值和准确性分别为93.3%、85.7%、97.7%、66.7%、92.3%和90.9%、95.1%、83.3%、97.5%、94.2%。LAVA动态增强判断子宫内膜癌深肌层受侵的准确性高于T2WI诊断的准确性,差异有统计学意义(P<0.05)。结论 3.0T磁共振LAVA动态增强扫描有助于提高子宫内膜癌肌层浸润术前诊断的准确性。  相似文献   

20.
PURPOSE: To prospectively evaluate the feasibility of ferumoxtran-10-enhanced magnetic resonance (MR) imaging at high magnetic field strength (3.0 T) and to compare image quality between 1.5- and 3.0-T MR imaging in terms of lymph node detection in patients with prostate cancer. MATERIALS AND METHODS: This study was institutional review board approved, and all patients gave written informed consent. Forty-eight consecutive patients aged 51-79 years (mean, 65.5 years) with prostate cancer were enrolled. T2*-weighted 1.5- and 3.0-T MR images of the pelvis were acquired in a sagittal plane parallel to the psoas muscle 24 hours after ferumoxtran-10 administration. A pelvic and body phased-array coil was used and yielded an in-plane resolution of 0.56 x 0.56 x 3.00 mm at 1.5 T and 0.50 x 0.50 x 2.50 mm at 3.0 T. All images were evaluated by three readers for total image quality, lymph node border delineation, muscle-fat contrast, and vessel-fat contrast. Statistical significance was calculated by using the Mann-Whitney U test. Subsequently, the general linear mixed model was used to estimate the contributions of three factors-patient, reader, and technique-to the variability of the imaging results. RESULTS: Significantly (P < .05) better muscle-fat contrast, vessel-fat contrast, lymph node border delineation, and total image quality were observed at 3.0-T MR imaging. The general linear mixed model revealed that the variability of all results could be attributed to the use of 3.0-T imaging. CONCLUSION: Ferumoxtran-10-enhanced MR imaging can be performed at high magnetic field strengths and result in improved image quality, which may lead to improved detection of small positive lymph nodes.  相似文献   

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