变应性鼻炎的中药治疗

目的考察中药治疗变应性鼻炎疗效。方法患者随机分为三组,分别使用中药玉屏风散加味、麻黄附子细辛汤加味、黄芪建中汤加味治疗变应性鼻炎。结果三组总有效率分别为78.3%、75.4%、79.6%。χ2比较三组总有效率无显著性差异（P〉0.05）。结论中药对变应性鼻炎有较好的效果,但其治疗机理有待进一步明确。     

四君子汤加味联合常规西医综合疗法治疗慢性胃炎的临床研究

目的研究四君子汤加味联合常规西医综合疗法治疗慢性胃炎疗效。方法将符合筛选标准的130名慢性胃炎患者随机分为两组,均采用西医综合治疗,治疗组加用四君子汤加味,并根据患者症状加减药物,8周为1个疗程,疗程结束后,评价两组患者疗效。结果治疗组患者总有效率(95.00%)高于对照组(70.00%)(P<0.01)结论四君子汤加味联合常规西医综合疗法治疗慢性胃炎效果优于单用西医治疗。     

两种药物脱敏治疗变应性鼻炎的疗效对比观察

目的探讨两种药物脱敏治疗变应性鼻炎的疗效对比情况。方法将64例变应性鼻炎患者均分为两组,治疗组采用布地奈德治疗,对照组盐酸司他斯汀治疗。结果治疗组32名变应性鼻炎患者中,显效22例,有效9例,无效1例,总有效率为96.9%;对照组32名变应性鼻炎患者中,显效20例,有效10例,无效2例,总有效率为93.8%。两组治疗有效率相比无显著性差异（P〉0.05）。结论两种药物均是治疗变应性鼻炎的有效方法 ,值得临床推广应用。     

针刺四缝穴联合中药治疗小儿疳积48例疗效观察

目的:观察针刺四缝穴联合中药口服治疗小儿疳积的疗效.方法:95例患儿随机分为2组,治疗组48例采用针刺四缝穴联合口服四君子汤加减,对照组47例仅给予口服中药.结果:治疗组48例中显效26例,有效18例,无效4例,总有效率91.7%;对照组47例中显效14例,有效17例,无效16例,总有效率66.0%,2组总有效率比较差异有高度统计意义(P＜0.01).结论:针刺四缝穴治疗小儿疳积临床疗效确切,具有健脾消积、理气醒胃的功效.     

西替利嗪联合鼻灵滴剂治疗变应性鼻炎600例

目的:观察西替利嗪联合鼻灵治疗变应性鼻炎的临床疗效.方法:治疗组:600例,睡前口服西替利嗪10 mg,qd;对照组200例,睡前口服氯雷他定10 mg,qd,两组均用鼻灵滴剂滴鼻,tid,每次2滴,均24 d为1个疗程.结果:治疗组显效518例,有效72例,无效10例,总有效率98.3%;对照组显效170例,有效24例,无效6例,有效率97.0%.两组差异无显著性.结论:因西替利嗪价格较氯雷他定低,故西替利嗪联合鼻灵应为基层医院、乡村及低收入患者治疗变应性鼻炎的首选方案.     

自拟补阳还五汤加味治疗心脏期前收缩的疗效观察

目的:观察自拟补阳还五汤加味治疗心脏期前收缩的效果。方法:将180例心脏期前收缩患者随机分为观察组和对照组,每组90例,观察组采用自拟补阳还五汤加味治疗;对照组采用静脉滴注丹参注射液,3周为1个疗程。观察并比较两组患者的治疗效果。结果:观察组显效37例,好转35例,无效18例,总有效率为80%;对照组显效26例,好转28例,无效36例,总有效率60%。观察组治疗效果优于对照组(P<0.05)。结论:采用自拟补阳还五汤加味治疗心脏期前收缩效果优于静脉滴注丹参注射液。     

四君子汤加味治疗慢性糜烂性胃炎99例

目的 观察四君子汤加味治疗慢性糜烂性胃炎的临床疗效.方法 选取99例慢性糜烂性胃炎患者随机分为治疗组50例和对照组49例.治疗组用四君子汤加味治疗,对照组口服雷尼替丁胶囊、阿莫西林胶囊、硫糖铝片.两组治疗1个疗程后比较治疗.结果 治疗组总有效率为96.0%,对照组为71.4%(P<0.05).结论 四君子汤加味治疗慢性糜烂性胃炎有益气健脾、活血化瘀、增强免疫力等功效.     

炙甘草汤加味治疗频发室性早搏的效果研究

目的探讨炙甘草汤加味治疗频发性室性早搏的临床疗效。方法随机将2016年1月至2018年5月本院收治的120例频发性室性早搏患者分到观察组(n=60例)和对照组(n=60例),观察组患者采取炙甘草汤加味治疗,对照组患者采取可达龙治疗,对比分析两组患者的临床疗效。结果观察组临床总有效率为91.67%(55/60),其中无效5例,有效15例,显效40例;对照组临床总有效率为78.33%(47/60),其中无效13例,有效18例,显效29例;两组比较,P <0.05。结论在频发性室性早搏患者中施以炙甘草汤加味治疗,能有效改善患者的临床症状,并能有效提高临床疗效。     

鼻内镜下手术加微电脑射频治疗变应性鼻炎的临床研究

目的研究鼻内镜下手术加微电脑射频治疗变应性鼻炎的临床疗效。方法回顾性分析采用鼻内镜下手术加XVC-Ⅱ型微电脑射频治疗仪治疗60例变应性鼻炎患者。结果治疗60例变应性鼻炎患者,经手术加微电脑射频治疗后随访观察1年,显效54例(90%)。有效4例(6.7%),无效2例,总有效率96.7%。结论手术加微电脑射频是治疗变应性鼻炎的有效方法。     

中药结合针刺治疗坐骨神经痛150例疗效观察

目的观察中药结合针刺疗法治疗坐骨神经痛的临床疗效。方法选取150例坐骨神经痛患者,分为治疗组和对照组,治疗组患者采用中药结合针刺疗法治疗,对照组患者仅采用针刺疗法治疗,治疗2个疗程,对两组患者的疗效进行比较。结果治疗组显效率30/74(40.54%)、总有效率70/74(94.59%),对照组显效率20/73(27.40%)、总有效率54/73(73.98%),治疗组疗效明显优于对照组,差异有统计学意义(P0.05)。结论中药结合针刺治疗坐骨神经痛能够明显提高疗效,具有较好的临床意义。     

颅脑损伤患者并发肺部感染的护理体会

目的：为了使并发肺部感染的病人更多、更好、更早的痊愈。方法：通过对32例颅脑外伤并发肺部感染病人的严密观察,采取更换体位、超声雾化、有效排痰训练等有效的护理措施干预,从而控制了肺部感染。结果：痊愈17例,占53.1%;显效12例,占37.5%,无效2例,占6.2%;死亡1例,占3.1%;实践证明,有效的护理干预对提高患者治疗成功率有着重要意义。     

卡马西平联用尼美舒利相关粒细胞缺乏症

1例78岁男性患者因带状疱疹神经痛、慢性阻塞性肺疾病合并感染,给予头孢唑肟钠（2.25 g静脉滴注,1次/d）、卡马西平（0.2 g口服,2次/d）、尼美舒利（100 mg口服,2次/d）、二羟丙茶碱（0.5 g静脉滴注,1次/d）、甲钴胺（0.5 mg口服,3次/d）、地塞米松（5 mg,静脉滴注1次）、盐酸哌替啶（25 mg,肌内注射1次）和盐酸布桂嗪（100 mg,肌内注射3次）等药物治疗。第7天,停用头孢唑肟钠,改为磷霉素钠（8 g静脉滴注,1次/d）。第11天,血常规检查示白细胞计数1.6×10^9/L,中性粒细胞0.03,中性粒细胞绝对值0.1×10^9/L,淋巴细胞绝对值0.9×10^9/L。立即停用所有药物,给予对症支持治疗。第15天,外周血白细胞计数0.9×10^9/L,中性粒细胞0.02,中性粒细胞绝对值0.1×10^9/L,淋巴细胞绝对值0.7×10^9/L。行骨髓穿刺检查,诊断为粒细胞缺乏症。第17天患者出现右肺气胸、肺不张。第20天出现急性呼吸衰竭、多脏器衰竭合并重症感染,经抢救无效死亡。     

Satisfaction with information and its relationship with adherence in patients with chronic pain

□ Due to the nature of chronic pain it would be expected that patients are highly adherent to their pain medication. However, results from this study have shown that 23 per cent of patients often or always avoid using their pain medication, 13.4 per cent often or always alter dosages, and 10.3 per cent often or always stop taking their medication for a while. This suggests intentional non‐adherence to pain medication □ Less than 50 per cent of respondents were satisfied with information provided on side effects, what to do if side effects occur, and possible interactions with other medication □ Patients' satisfaction with information about their medication was related to self‐reported adherence; greater satisfaction was associated with higher self‐reported adherence     

Genomic profiling associated with recurrence in patients with rectal cancer treated with chemoradiation

PURPOSE: Stage II and III adenocarcinoma of the rectum has an overall 5-year survival rate of approximately 50%, and tumor recurrence remains a major problem despite an improvement in local control through chemotherapy and radiation. The efficacy of chemoradiation therapy may be significantly compromised as a result of interindividual variations in clinical response and host toxicity. Therefore, it is imperative to identify those patients who will benefit from chemoradiation therapy and those who will develop recurrent disease. In this study, we tested whether a specific pattern of 21 polymorphisms in 18 genes involved in the critical pathways of cancer progression (i.e., drug metabolism, tumor microenvironment, cell cycle regulation, and DNA repair) will predict the risk of tumor recurrence in rectal cancer patients treated with chemoradiation. PATIENTS AND METHODS: A total of 90 patients with Stage II or III rectal cancer treated with chemoradiation were genotyped using polymerase chain reaction (PCR)-based techniques for 21 polymorphisms. RESULTS: A polymorphism in interleukin (IL)-8 was individually associated with risk of recurrence. Classification and regression tree analysis of all polymorphisms and clinical variables developed a risk tree including the following variables: node status, IL-8, intracellular adhesion molecule-1, transforming growth factor-beta, and fibroblast growth factor receptor 4. CONCLUSION: Genomic profiling may help to identify patients who are at high risk for developing tumor recurrence, and those who are more likely to benefit from chemoradiation therapy. A larger prospective study is needed to validate these preliminary data using germline polymorphisms on tumor recurrences in rectal cancer patients treated with chemoradiation.     

甘草酸单铵结合氦-氖激光治疗银屑病62例

目的用甘草酸单铵结合低能量氦-氖激光,观察治疗银屑病患者。方法62例寻常型银屑病患者,分为两组,A组用低能量氦-氖激光血管内照射,同时用甘草酸单铵静脉滴注,共36例;B组仅用甘草酸单铵,共26例。通过30d治疗。结果总有效率82.2%,其中A组有效率88.9%,B组73.1%(经Ridit检验,U＝2.76,P＜0.01),两组差异有极显著性意义。结论甘草酸单铵结合氦-氖激光治疗银屑病,比单用甘草酸单铵效果好。     

A fetus with meckel-gruber syndrome associated with isomerism

Abstract. Meckel-Gruber syndrome (MKS) is an autosomal recessive lethal malformation. As far as we know, the rate of incidence for the syndrome is 0.02 per 10,000 births. It is estimated that Meckel-Gruber syndrome accounts for 5% of all neural tube defects in Finland. Objective. The aim of this study is to present a case of a fetus with Meckel-Gruber syndrome associated with complete left isomerism. Method. The fetus was obtained after medical interruption of the pregnancy during the fifteenth gestational week. The mother was 36 years old and in a consanguineous marriage. The antenatal ultrasound examination revealed a polymalformative syndrome, leading to a postmortem examination. The fetopathological study of the fetus was conducted at the Centre for Maternity and Neonatology, Tunis, Tunisia, in 2008. Results. The female fetus had a significantly deformed ballooning abdomen, pes equinovarus, flexion of the wrist and a total posterior cleft palate. The central nervous system abnormalities were occipital encephalocele, cystic dilatation of the fourth ventricle, agenesis of corpus callosum and hydrocephalus. The study of the internal organs found dextrocardia, irregular lobulation of the lungs, left isomerism, and polysplenia. The microscopic examination revealed bilateral cystic dilation of the kidneys, fibrous proliferation of the liver and ectasic dilatation of the billiary ducts, representing a ductal plate malformation of the liver. Conclusion. The case is diagnosed with Meckel-Gruber syndrome associated with complete left isomerism, cleft palate and possibly Dandy-Walker syndrome.