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1.
Background
The Pediatric Laparoscopic Surgery (PLS) simulator is the only validated tool for pediatric Minimal Access Surgery. Construct validity (the ability to discriminate between novice, intermediate and expert) for the PLS simulator had previously been established on the basis of the total PLS score, as well as the individual performance on three of the five tasks. We describe the process and methods used to establish independent construct validity for a fourth task: pattern-cutting.Methods
After considering various options for the possible modifications of the task itself, we retrospectively altered the way the pattern-cutting task was scored by modifying the weighting of precision versus time without changing the task itself. This was subsequently tested prospectively at the 2011 Canadian Association of Pediatric Surgeons meeting.Results
Modification in the scoring metrics allowed differentiation within a previously tested cohort of 84 candidates (20 novices: score = 48 ± 16, 19 intermediates: score = 59 ± 18, 45 experts: score = 69 ± 12 p = 0.01). This was validated prospectively in a cohort of 18 experts and 7 intermediates (65 ± 8, 54 ± 17 p = 0.03).Conclusions
Construct validity for the pattern-cutting task was established by modification of the scoring metrics. This was validated both retrospectively and prospectively. 相似文献2.
Katherine A. Barsness Deborah M. Rooney Lauren M. Davis Anthony C. Chin 《Journal of pediatric surgery》2014
Purpose
A validated high fidelity simulation model would provide a safe environment to teach thoracoscopic EA/TEF repair to novices. The study purpose was to evaluate validity evidence for performance measures on an EA/TEF simulator.Methods
IRB-exempt data were collected from 12 self-reported “novice” and 8 “experienced” pediatric surgeons. Participants evaluated the EA/TEF repair simulator using survey ratings that were analyzed for test content validity evidence. Additionally, deidentified operative performances were videotaped and independently rated by two surgeons using the Objective Structured Assessment for Technical Skills (OSATS) instrument. Novice and experienced OSATS were compared with p < .05 significant.Results
Participants had high overall simulator ratings. Internal structure was supported by high interitem consistency (α = .95 and .96) and interrater agreement (ICC) [.52, .84] for OSATS ratings. Experienced surgeons performed at a significantly higher level than novices for all five primary and two supplemental OSATS items (p < .05).Conclusion
Favorable participant ratings indicate the simulator is relevant to clinical practice and valuable as a learning tool. Further, performance ratings can discriminate experienced and novice performances of EA/TEF repair. These findings support the use of the simulator for performance assessment, representing the first validated measures from a simulator intended for pediatric surgical training. 相似文献3.
Aodhnait S. Fahy Kai-Ho Fok Bojan Gavrilovic Monica Farcas Brian Carrillo Justin T. Gerstle Georges Azzie 《Journal of pediatric surgery》2018,53(12):2480-2487
Background
Simulation is becoming more important in the teaching and assessment of technical skills. The purpose of this study was to refine the use of motion analysis parameters (MAPs) to assess performance of a defined task in low-cost pediatric laparoscopic simulators of differing size.Methods
105 participants performed a defined intracorporeal suturing task in large and small pediatric laparoscopic simulators. Outcomes included MAPs — path length, extreme velocity events, and extreme acceleration events in all available degrees of freedom for novices, intermediates, and experts. ANOVA p < 0.05 was judged significant.Results
In the smaller simulator, all MAPs discriminated between expertise groups in all degrees of freedom. In the larger simulator, all but one MAP discriminated between expertise groups. Experts demonstrated the greatest variability in performance between the larger and smaller simulators.Conclusion
Analysis of motion in the performance of a defined intracorporeal suturing task allowed discrimination between novices, intermediates, and experts in large and small low-cost pediatric laparoscopic simulators. Further refinement in MAPs will determine their role in surgical education.Level of evidence
Not applicable. 相似文献4.
F. Lenfant D. Pean M. de Mesmay A. Maurice S. Decagny C. Lejus O. Langeron 《Annales fran?aises d'anesthèsie et de rèanimation》2014
Goal of the study
To evaluate a single-use fiberscope, the Ascope-Trainer™, for the training in the intubation under fiberscope.Type of study
Prospective randomized study approved by the local ethic committee.Methodology
After evaluation of their level of expertise, “experienced” or “novices” in intubation under fiberscope, the doctors attending the Training for Referents in Difficult Airway Management performed a test on labyrinth with a standard fiberscope (T1). After they were assigned to two groups, training with the Ascope-Trainer™ (group A, n = 35) or with a classic fiberscope (group C, n = 29), they trained during 15 minutes and performed a new test (T2). An analysis of variance was used to compare means. A goal for the training was determined according to the “experienced” doctors’ mean T1. A test of Khi2 was used for the comparison of the number of participants having reached this goal as well as the progress in both groups A and C.Results
The T1 in the “experienced” group was 76 ± 31 s and the training improved significantly T2 (53 ± 17 s). Considering the novices, T2 was significantly lower than T1 in the group A (77 ± 38 s versus 135 ± 68 s) as well as in C (64 ± 28 s versus 122 ± 60 s), and the proportion of the novices having reached the goal of training was comparable in both groups.Conclusions
Because its use is similar to the standard fiberscope, the Ascope-Trainer™ may be interesting for this type of training. 相似文献5.
Emmanuel M. Illical Dana J. FarrellPeter A. Siska Andrew R. EvansGary S. Gruen Ivan S. Tarkin 《Injury》2014
Objectives
To compare elbow range of motion (ROM), triceps extension strength, and functional outcome of AO/OTA type A distal humerus fractures treated with a triceps-split or -sparing approach.Design
Retrospective review.Setting
Two level one trauma centres.Patients
Sixty adult distal humerus fractures (AO/OTA 13A2, 13A3) presenting between 2008 and 2012 were reviewed. Exclusion criteria removed 18 total patients from analysis and three patients died before final follow-up.Intervention
Patients were divided into two surgical approach groups chosen by the treating surgeon: triceps split (16 patients) or triceps sparing (23 patients).Main outcome measurements
Elbow ROM and triceps extension strength testing were completed in patients after fractures had healed. All patients were also given the Disabilities of the Arm, Shoulder, and Hand (DASH) questionnaire.Results
Compared to the triceps-split cohort, the triceps-sparing cohort had greater elbow flexion (sparing 143 ± 7° compared to split 130 ± 12°, p = 0.03) and less extension contracture (sparing 6 ± 8° compared to split 23 ± 4°, p < 0.0001). Triceps strength compared to the uninjured arm also favoured the triceps-sparing cohort (sparing 88.9 ± 28.3% compared to split 49.4 ± 17.0%, p = 0.007). DASH scores were not statistically significant between the two cohorts (sparing 14.5 ± 12.2 compared to split 23.6 ± 22.3, p = 0.333).Conclusions
A triceps-sparing approach for surgical treatment of extra-articular distal humerus fractures can result in better elbow ROM and triceps strength than a triceps-splitting approach. Both approaches, however, result in reliable union and similar functional outcome.Level of evidence
Level III. 相似文献6.
Munenori Uemura Morimasa Tomikawa Ryuichi Kumashiro Tiejun Miao Ryota Souzaki Satoshi Ieiri Kenoki Ohuchida Alan T. Lefor Makoto Hashizume 《The Journal of surgical research》2014
Background
The number of operations performed by a surgeon may be an indicator of surgical skill. The hand motions made by a surgeon also reflect skill and level of expertise. We hypothesized that the hand motions of expert and novice surgeons differ significantly, regardless of whether they are familiar with specific tasks during an operation.Methods
This study compared 11 expert surgeons, each of whom had performed >100 laparoscopic procedures, and 27 young surgeons, each of whom had performed <15 laparoscopic procedures. Each examinee performed a specific skill assessment task, in which instrument motion was monitored using magnetic tracking system. We analyzed the paths of the centers of gravity of the tips of the needle holders and the relative paths of the tips using two mathematical methods of detrended fluctuation analysis and unstable periodic orbit analysis.Results
Detrended fluctuation analysis showed that the exponent in the function describing the initial scaling exponent (α1) differed significantly for experts and novices, being close to 1.0 and 1.5, respectively (P < 0.01). This indicated that the expert group had a greater long-range coherence with an intrinsic sequence and smooth continuity among a series of motions. Likewise, unstable periodic orbit analysis showed that the second period of unstable orbit was significantly longer for experts in comparison with novices (P < 0.01). This demonstrates mathematically that the hands of experts are more stable when performing laparoscopic procedures.Conclusions
Objective evaluation of hand motion during a simulated laparoscopic procedure showed a significant difference between experts and novices. 相似文献7.
Morgan Rouprêt Vincent Misraï Christophe VaessenVincent Cardot Florence CourFrançois Richard Emmanuel Chartier-Kastler 《European urology》2010
Background
Implantation of an artificial urinary sphincter (AUS) is used as a last resort in women with stress urinary incontinence (SUI).Objective
To assess the early functional outcome after laparoscopic placement of an AUS in women.Design, setting, and participants
Twelve women with type 3 SUI underwent a laparoscopic AUS placement between 2006 and 2008. Eleven (92%) had previously undergone anti-incontinence procedures.Intervention
The AUS was implanted with laparoscopic access either preperitoneally or intraperitoneally. The cuff was placed around the bladder neck between the periurethral fascia and the vagina.Measurements
Perioperative complications were reviewed. To assess resolution of urinary incontinence, all patients were seen at 1, 3, 6, and 12 mo after the surgery and yearly thereafter.Results and limitations
The mean age of subjects was 56.7 ± 12 yr (33–78). The mean body mass index was 24 ± 2.3 (20–25). The mean preoperative closure pressure was 22 ± 10.9 cmH2O (4–35). The mean operative time was 181 ± 39 min [110–240]. Intraoperative complications occurred in three women (25%), with bladder (n = 2) and vaginal (n = 2) injuries. These complications required open conversion. AUS implantation was postponed in one case. The mean hospital stay was 7 ± 2.3 d (3–11). The bladder catheter was removed after a mean time of 10 ± 8 d (2–30). Urinary retention was observed in five cases (45%) after bladder catheter removal. AUS activation was done 4–14 wk after implantation. Mean follow-up was 12.1 ± 8 mo (5.2–27). Incontinence was completely resolved in eight women (88%) who underwent complete laparoscopic procedure. The main limitation of the study was the limited length of follow-up.Conclusions
AUS implantation can be successfully achieved by laparoscopy. It appears to be technically feasible. These results are still preliminary, and further studies of larger populations with longer follow-up are needed to make any statement regarding surgical strategy. 相似文献8.
Anwar Abdelgayed Ebid Shamekh Mohamed El-Shamy Amira Hussin Draz 《Burns : journal of the International Society for Burn Injuries》2014
Objective
The aim of this study was to investigate the effects of isokinetic training program on muscle strength, muscle size and gait parameters after healed pediatric burn.Design
Randomized controlled trial.Subjects
Thirty three pediatric burned patients with circumferential lower extremity burn with total body surface area (TBSA) ranging from 36 to 45%, and ages from 10 to 15 years participated in the study and were randomized into isokinetic group and a control group. Non-burned healthy pediatric subjects were assessed similarly to burned subjects and served as matched healthy controls.Methods
Patients in the isokinetic group (n = 16) participated in the isokinetic training program for 12 weeks for quadriceps dominant limb, 3 times per week, at angular velocity 150°/s, concentric mode of contraction, time rest between each set for 3 min, 3 sets/day and control group (n = 17) participated in home based physical therapy exercise program without isokinetic.Main measures
Assessment of quadriceps strength by isokinetic dynamometer, quadriceps size and gait parameters were performed at baseline and at the end of the training period for both groups.Results
Patients in isokinetic group showed a significant improvement in quadriceps strength, quadriceps size and gait parameters as compared with those in the control group. Quadriceps strength and percentage of improvement was 79.25 ± 0.93 Nm (68.40%) for isokinetic group and 51.88 ± 1.31 Nm (9.84%) for the control group. Quadriceps size and percentage of improvement was 31.50 ± 0.89 cm (7.47%) for isokinetic group and 29.26 ± 1.02 cm (1.02%) for the control group. Stride length, step length, velocity and cadence and percentage of improvement for isokinetic group was 135.50 ± 2.82 (53.97%), 63.25 ± 2.97 (63.77%), 135.94 ± 1.65 (81.42%), 137.63 ± 1.36 (66.96%) and for the control group was 94.00 ± 2.69 (6.68%), 43.76 ± 1.34 (15.15%), 81.11 ± 1.91 (8.6%), 90.35 ± 1.32 (9.01%) respectively.Conclusions
Participation in the isokinetic training program resulted in a greater improvement in quadriceps muscle strength, size and gait parameters in pediatric burn. 相似文献9.
Luigi Schips Francesco BerardinelliFabio Neri Fabiola Raffaella TamburroLuca Cindolo 《European urology》2013
Background
Laparoendoscopic single-site surgery (LESS) has emerged as a natural progression from standard laparoscopy aiming to further minimize the morbidity of urologic procedures.Objective
To describe our technique and report the surgical and functional outcomes of unclamped LESS partial nephrectomy (PN) in the treatment of small renal masses (SRMs).Design, setting, and participants
Prospective evaluation of pre- and postoperative variables of patients undergoing the LESS-PN without ischemia between 2009 and 2012. The indications were single exophytic SRMs.Surgical procedure
Unclamped LESS-PN was performed through a transperitoneal approach. A pararectal Hasson access technique was preferred. Single-port access was achieved via different single-port devices. A combination of straight and articulating laparoscopic instruments was used. The tumor was excised using bipolar scissors during normal renal perfusion. Hemostasis was achieved by bipolar electrocautery, parenchymal stitches, and hemostatic agents.Outcome measurements and statistical analysis
Demographic, operative, postoperative, and pathologic outcomes data were recorded and analyzed.Results and limitations
A total of 21 LESS-PN were performed (operative time: 111 ± 41 min; blood loss: 196 ± 195 ml: tumor size: 2.0 ± 0.3 cm). Neither conversion to open surgery nor transfusions occurred. Three patients required conversion to standard laparoscopy. Postoperatively, three complications (Clavien grades 2, 3a, and 4) were recorded. Pathologic examination revealed 14 clear cell carcinomas, four renal cysts, two oncocytomas, and one angiomyolipoma. Hospital stay was 4.4 ± 1.9 d. At the last follow-up (mean: 17 ± 11.5 mo), no port-site, local, or distant recurrences were detected. No significant variation in serum creatinine and estimated glomerular filtration rate was observed. Subjective scar evaluation indicated 66% of patients were very satisfied/enthusiastic. Study limitations include the small sample size, the lack of a control group, the short follow-up period, and the arbitrary measure of patient's scar perception.Conclusions
Unclamped LESS-PN for selected SRMs is a safe and feasible procedure providing favorable postoperative outcomes and ensuring high levels of subjective, cosmetic satisfaction. 相似文献10.
Sammy Al-Benna Kirsty Johnson William Perkins Ciaran O’Boyle 《Burns : journal of the International Society for Burn Injuries》2014
Introduction
Erosive pustular dermatosis (EPD) is a cutaneous condition, characterised by sterile pustular lesions, erosions and crusting. Extensive or infected disease may result in scarring. EPD has never been reported following burn. The aim of this study was to describe the presentation and management of EPD complicating burns wounds.Methods
A consecutive series of EPD cases secondary to burn.Results
Six cases were identified. In each case, erosive lesions and crusts were located at the site of burn or at the site of split skin grafting after tangential burn excision. All cases presented as failure to heal or repeated wound breakdown, despite standard burn wound management. Pain was a significant feature in all cases. Microbiological cultures demonstrated either benign colonising bacteria or no pathogens. Time to EPD diagnosis by the interdisciplinary team was 126 ± 27 days (mean ± SEM). Topical therapy with short course, potent corticosteroids resulted in clinical remission in 15 ± 2 days (mean ± SEM) without clinical relapses after 15 ± 4 months (mean ± SEM).Conclusion
EPD may occur following burns. EPD should be considered in the differential diagnosis of a non-healing burn wound and resolves readily with topical potent corticosteroid therapy. 相似文献11.
L. Tremelot A. Restoux C. Paugam-Burtz S. Dahmani L. Massias C. Peuch J. Belghiti J. Mantz 《Annales fran?aises d'anesthèsie et de rèanimation》2008
Objective
The anhepatic phase of orthotopic liver transplantation (OLT) is associated with significant changes in pharmacokinetics. The aim of this study was to compare the influence of this phase on propofol target concentrations during BIS guided target controlled infusion (TCI).Study design
Prospective study.Patients and methods
Eight patients aged 25 to 65 years, Child-Pugh status A-B scheduled for OLT were prospectively included. Anesthesia was performed using TCI of propofol (Diprifusor®, Marsh pharmacokinetic model), sufentanil and cisatracurium. Propofol target concentration was adjusted to maintain BIS values between 40 and 50.Results
To maintain stable BIS values, propofol target concentrations should be decreased during the anhepatic phase versus the dissection one (2.0 μg/ml ± 0.8 versus 3.0 μg/ml ± 0.9, p < 0.0001).Conclusion
BIS could be useful to titrate propofol infusion during the anhepatic phase of OLT. 相似文献12.
Ali Khalifeh Riccardo AutorinoRemi Eyraud Dinesh SamarasekeraHumberto Laydner Kamol PanumatrassameeRobert J. Stein Jihad H. Kaouk 《European urology》2013
Background
With the wider adoption of minimally invasive partial nephrectomy (PN), intermediate- and long-term outcomes data are needed to make firm conclusions about oncologic and functional efficacy, especially for robot-assisted PN (RPN).Objective
To report intermediate-term oncologic and renal functional outcomes of RPN.Design, setting, and participants
We performed a chart review of patients who had undergone RPN since June 2006; patients with a minimum of 2 yr of follow-up were included in this study. Length of follow-up was calculated from the date of surgery to the date of last clinical follow-up. Patients who were either lost to follow-up or who had follow-up outside of our center were sent surveys.Intervention
Transperitoneal RPN with or without hilar clamping.Outcome measurements and statistical analysis
The demographic, preoperative, and postoperative data were statistically analyzed. The Kaplan-Meier method was used to calculate overall survival (OS), cancer-specific survival (CSS), and cancer-free survival (CFS). Upstaging of chronic kidney disease (CKD) was calculated, as well. Univariate and multivariate analyses were performed to show predicting factors for the latest estimated glomerular filtration rate (eGFR).Results and limitations
Of 427 patients, 134 had a minimum follow-up of 2 yr, and 70 had a minimum of 3–6 yr of follow-up. The mean age was 59.1 ± 12.5 yr, body mass index (BMI) was 29.8 ± 6.2 kg/m2, and Charlson comorbidity index (CCI) score was 4.2 ± 1.6. The mean tumor size on computed tomography (CT) scan was 3.0 ± 1.6 cm, RENAL score was 7.2 ± 1.8, estimated blood loss (EBL) was 270.7 ± 291.9 ml, operative time was 189.1 ± 54.8 min, and warm ischemia time (WIT) was 17.9 ± 10.3 min. A total of two intraoperative complications (1.5%) and five high-grade Clavien complications (3.7%) occurred. Patients stayed on average for 3.7 ± 1.7 d in the hospital, and the average follow-up was 3.0 ± 0.9 yr. OS was 97.01% at 3 yr and 90.20% at 5 yr; CFS was 98.92% at 3 yr and 98.92% at 5 yr; and CSS was 99.04%, as projected by the Kaplan-Meier method. The mean preoperative GFR was 88.2 ± 0.8 ml/min per 1.73 m2; the latest postoperative GFR was 80 ± 24 ml/min per 1.73m2, with a 8 ± 17.4% change. There was a 20.2% upstaging of CKD postoperatively, but no patients started dialysis.Conclusions
This study reaffirms that RPN is effective in renal function preservation and oncologic control at an intermediate follow-up interval. 相似文献13.
Alexandre Mottrie Geert De Naeyer Peter Schatteman Paul Carpentier Mattia Sangalli Vincenzo Ficarra 《European urology》2010
Background
Robot-assisted partial nephrectomy (RAPN) is an emerging, minimally invasive technique to treat patients with small renal masses.Objective
To evaluate the impact of the learning curve on perioperative outcomes such as operative times and warm ischaemia times (WIT), blood loss, overall complications, and renal function impairment in patients who underwent RAPN.Design, setting, and participants
We collected prospectively the clinical and pathologic records of 62 consecutive patients who underwent RAPN between September 2006 and November 2009 for renal tumours at a nonacademic teaching institution by a single surgeon with extensive prior robotic experience.Interventions
The surgeon used transperitoneal RAPN with excision of an adequate rim of healthy peritumour renal parenchyma.Measurements
Perioperative parameters, pathologic outcome, and short-term outcomes for renal function were recorded. The effects of the learning curve on the previous reported perioperative and functional outcomes was studied.Results and limitations
The mean pathologic tumour size was 2.8 ± 1.3 cm. A pelvicaliceal repair was needed in 33 cases (53%). The mean console time was 91 ± 33 min (range: 52–180), with a mean WIT of 20 ± 7 min (range: 9–40). Warm ischaemia (<20 min) and console times were optimised after the first 30 (p < 0.001) and 20 cases (p < 0.001), respectively. Pathologic results yielded a positive surgical margin (PSM) rate of 2%. Mean creatinine level changed from a baseline value of 1.02 ± 0.38 mg/dl to 1.1 ± 0.7 mg/dl 3 mo after surgery. Estimated glomerular filtration rate changed from a baseline value of 81.17 ± 29 to 80.5 ± 29 (millilitres per minute per 1.73 m2) 3 mo postoperatively.Conclusions
RAPN is a viable option for nephron-sparing surgery in patients with renal carcinoma. Specifically, in the hands of a surgeon with extensive robotic experience, RAPN requires a short learning curve to reach WIT <20 min, console times <100 min, limited blood loss, and acceptable overall complication rates. 相似文献14.
Background
Partial nephrectomy (PN) for small renal masses provides effective oncologic outcomes. Single-port laparoscopic (SPL) and robotic surgeries are evolving approaches to advance minimally invasive surgery.Objective
To determine the feasibility of laparoscopic and robotic single-port PN.Design, setting, and participants
Since 2007, evaluation of patients undergoing SPL and single-port robotic (SPR) PN at a primary referral center was performed. Patients with small, solitary, exophytic-enhancing renal masses were selected. Patients with a solitary kidney, endophytic or hilar tumors, and previous abdominal and/or kidney surgery were excluded. Perioperative and pathologic data were entered prospectively into an institutional review board (IRB)–approved database.Interventions
Tumor location determined either an open Hasson transperitoneal or retroperitoneal approach. A single multichannel port or Triport provided intra-abdominal access. The Harmonic Scalpel was used for tumor excision under normal renal perfusion. The da Vinci surgical robot was used for SPR cases.Measurements
Patient demographics, perioperative, hematologic, and pathologic data as well as pain assessment using the Visual Analog Pain Scale (VAPS) were assessed.Results and limitations
A total of seven patients underwent single-port PN (SPL = 5, SPR = 2). One patient with a right anterior upper-pole mass required conversion from SPL to standard laparoscopy following tumor excision because of intraoperative bleeding. Pathology revealed six lesions compatible with renal cell carcinoma (RCC) and one benign cyst. One negative frozen section came back focally positive on final histopathology. All other surgical margins were negative. A mean difference of 3.0 ± 2.0 g/dl in hemoglobin was noted in all patients. Minimal pain was noted at discharge following both laparoscopic and robotic single-port surgery (VAPS = 1.7 ± 1.2 vs 1 ± 0.5/10).Conclusions
SPL and SPR PN is feasible for select exophytic tumors. Robotics may improve surgical capabilities during single-port surgery. 相似文献15.
Declan G. Murphy Michael KergerHelen Crowe Justin S. PetersAnthony J. Costello 《European urology》2009
Background
Robotic-assisted laparoscopic radical prostatectomy (RALP) using the da Vinci® surgical system (Intuitive Surgical, Sunnyvale, CA) is increasingly used for the management of localised prostate cancer.Objective
We report the operative details and short-term oncological and functional outcome of the first 400 RALPs performed at our unit.Design, setting and participants
From December 2003 to August 2006, 400 consecutive patients underwent RALP at our institution. A prospective database was established to record the relevant details of all RALP cases.Surgical procedure
A six port transperitoneal approach using a 4-arm da Vinci® system was used to perform RALP. This database was reviewed to establish the operative details and oncological and functional outcome of all patients with a minimum of 12 months follow-up.Measurements
Perioperative characteristics and outcomes are reported. Functional outcome was assessed using continence and erectile function questionnaires. Biochemical recurrence (prostate-specific antigen (PSA) ≥0.2 ng/mL) is used as a surrogate for cancer control.Results and limitations
The mean age ± standard deviation (SD) was 60.2 ± 6 years. Median PSA level was 7.0 (interquartile range (IQR) 5.3–9.6) ng/mL. The mean operating time ± SD was 186 ± 49 mins. The complication rate was 15.75% comprising Clavien grade I-II and Clavien grade III complications in 10.5% and 5.25% of patients respectively.The overall positive surgical margin rate was 19.2% with T2 and T3 positive margin rates of 9.6% and 42.3% respectively. The biochemical recurrence-free survival was 86.6% at a median follow-up of 22 (IQR = 15–30) months. At 12 months follow-up, 91.4% of patients were pad-free or used a security liner. Of those men previously potent (defined as Sexual Health Inventory for Men [SHIM] score ≥21) who underwent nerve-sparing RALP, 62% were potent at 12 months.Conclusions
The safety and feasibility of RALP has already been established. Our initial experience with this procedure shows promising short-term outcomes. 相似文献16.
A. Guillon F. Espitalier S. Ehrmann E. Masseret M. Laffon 《Annales fran?aises d'anesthèsie et de rèanimation》2013
Objective
Pulse pressure variation (ΔPP) has been demonstrated to be an accurate dynamic parameter to predict fluid responsiveness. However, the impact of different ventilator modes on this parameter is unknown. We compared ΔPP values calculated alternatively during pressure- and volume-controlled ventilation.Study design
Double-blind randomized study, cross-over design.Patients
Patients in intensive care unit after a cardiac surgery.Method
Patients were ventilated alternatively in both ventilator modes (according to the randomization): volume-controlled ventilation (VVC) and pressure-controlled ventilation (VPC). Other parameters of ventilation were identical. ΔPP values were calculated for each patient in both ventilator modes.Results
Among the 26 patients analyzed, mean ΔPP value was de 14.0 ± 7.3% in VVC and 11.8 ± 6.2% in VPC (P < 0,0001). On Bland-Altman representation, mean bias was +2.2 ± 2.3% and inferior and superior limits of agreement were respectively −2.3 and 6.7%. Arterial blood pressure and central venous pressure were not modified.Conclusion
ΔPP values obtained with both ventilator modes were not interchangeable. On average, ΔPP decreases by more than two points in the passage VVC to VPC for a given patient, all others things being equal. 相似文献17.
Christopher M. Dodgion Ankush Gosain Andrew Rogers Shawn D. St. Peter Peter F. Nichol Daniel J. Ostlie 《Journal of pediatric surgery》2014
Purpose
Recent reports suggest that an abbreviated bed rest protocol (ABRP) may safely reduce length of stay (LOS) and resource utilization in pediatric blunt spleen and liver injury (BSLI) patients. This study evaluates national temporal trends in BLSI management and estimates national reduction in LOS using an ABRP.Methods
Pediatric patients (< 18 years old) sustaining BLSI were identified in the Kids’ Inpatient Database from 2000 to 2009. Yearly rates of injury and operative intervention were examined and stratified by type of injury. APSA guidelines and the reported ABRP were applied based on abbreviated injury score (AIS) and compared with actual LOS.Results
22,153 patients were identified. Over the study period, operative rates for spleen and liver injuries and overall mortality significantly declined: LOS = 3.1 days (± 1.6) and 2.7 days (± 1.9) for spleen and liver, respectively. If APSA guidelines were followed, the rates were LOS = 3.7 days (± 1.1) and 3.4 days (± 0.7), respectively. Application of the ABRP would result in LOS = 1.3 days (± 0.5) for all BSLI patients. An ABRP could potentially save 1.7 hospital days/patient or 36,964 patient hospital days nationally.Conclusion
Our study confirms a significant national decrease in operative intervention and overall mortality in patients with BSLI. Additionally, it appears that a shorter observation period than the APSA guidelines is being utilized. The implementation of ABRP holds potential in further reducing LOS and resource utilization. 相似文献18.
Stephan Hruby Manuela Sieberer Tobias Schätz Neil Jones Reinhold Zimmermann Günter Janetschek Lukas Lusuardi 《European urology》2013
Background
Eraser, a 1318-nm diode laser, has been used for 15 yr for resection of lung metastases. It was recently introduced in urology for small kidney tumors and for the treatment of benign prostatic obstruction.Objective
To demonstrate on video our technique of Eraser laser enucleation of the prostate (ELEP) and report our experience.Design, setting, and participants
From June 2010 to October 2011, 43 consecutive patients were prospectively evaluated. All of them had lower urinary tract symptoms suggestive of benign prostatic obstruction and a mean prostate size of 59.9 ml (range: 34–89 ml) on transrectal ultrasound. Their mean prostate-specific antigen value was 3.4 ng/ml (range: 0.8–5.0 ng/ml); mean maximum flow rate (Qmax), 6.9 ml/s (range: 2–11 ml/s); mean International Prostate Symptom Score (IPSS), 25.9 (range: 18–32); and mean postvoid residual (PVR), 170.5 ml (range: 60–330 ml).Surgical procedure
The details of the technique are shown on video.Outcome measurements and statistical analysis
Success was defined as patients being able to void with improved IPSS, Qmax, PVR volume, and ameliorated quality of life.Results and limitations
The mean operating time was 67.0 ± 11.43 min. Mean serum hemoglobin was 15.1 ± 0.87 g/l before, and 14.39 ± 0.94 g/l after surgery. Mean blood loss was 115.90 ± 98.12 ml. No blood transfusions were required. All patients had their catheters removed within 2 d and were able to void spontaneously after this time. Significant improvements were noted in Qmax, quality of life, IPSS, and PVR volume from baseline to each follow-up time point.Based on the validated Clavien-Dindo system, we observed one grade 1d complication, one grade 2 complication, and one grade 3b complication.Conclusions
ELEP is a safe and reproducible method for relieving bladder outflow obstruction and lower urinary tract symptoms. Its advantages include minimal blood loss, short catheterization time, and a brief hospital stay. 相似文献19.
Background
Although tension-band wiring is the most widely used technique to fix patellar fractures, metal implant-related complications including implant failure and postoperative pain are very common and additional procedures are often necessary to treat the complications. The purpose of this study is to evaluate a totally metal-free technique using a transosseous suturing method and to compare it with the traditional fixation technique.Method
A total of 25 patients (mean age of 59.60 years) with displaced patellar fractures treated by a transosseous suturing technique were compared with a 1:1 matched historical control group that underwent modified tension-band-wire fixation. Union time, union rate, operation time, number of procedures, mean hospitalisation days and complications were compared between cases and controls.Results
Union time (8.43 ± 2.92 vs. 8.64 ± 2.82 weeks) and operation time (69.00 ± 19.31 vs. 64.89 ± 14.27 min) were not different between the two groups. Mean hospitalisation days (4.04 ± 1.40 vs. 5.76 ± 1.50 days; P < 0.001), number of procedures and the frequency of complications were significantly lower in the transosseous suturing group.Conclusion
The transosseous suturing technique is safe and effective in the transverse or comminuted fractures of the patella. The complication rate is significantly lower than with the tension-band-wiring technique. 相似文献20.