右乳癌合并小细胞肺癌1例

患者,女性,50岁,因发现右乳肿物4年于1988年10月确诊为右乳癌,并行右乳癌根治术,术后病理为:乳腺浸润性导管癌术后行Co~(60)放疗,CVA方案化疗,经过顺利。1991年12月因右胸壁肿物行肿物穿刺细胞学检查找到癌细胞,证实为右乳癌术后胸壁复发,再次行放疗,总量达60Gy后,行手术切除。1993年7月,因刺激性咳嗽,痰中带血1个月,行支气管镜检查,诊断为左肺中心型肺癌,病理诊断为:未分化小     

阴囊Paget病1例

1 病案摘要 患者男性,59岁。因“阴囊Paget病术后1年半,左腹股沟转移癌术后8个月”至我院就诊。患者于2015年1月因反复阴囊湿疹至盐城市第三人民医院行病理活检确诊为阴囊湿疹样癌,遂至上海华山医院行手术切除,术后未进一步治疗。2015年9月发现左腹股沟肿块,再次至上海华山医院行体表肿块切除,病理活检示：转移性癌（图1）。     

原发性宫颈混合性生殖细胞瘤1例

1 临床资料 患者女性, 53岁,于1998年9月因阴道不规则流血半年,检查发现"宫颈腺癌",10月13日在我院行广泛全子宫切除加盆腔淋巴结清扫术.术后病理示:宫颈内膜腺癌.此后定期复查.     

盆腔侵袭性血管黏液瘤一例报道并文献复习

1 病例报告 患者女,48岁,因发现右臀部肿物1年,于2016-03-10入院.既往病史:患者8年前因右臀部肿物于济南军区总医院行手术,术后病理确诊为盆底神经纤维瘤(病理号:087076).2015-03患者再次发现右臀部肿物并逐渐增大,近4个月肿物明显增大,患者感腰骶部疼痛,下腹部坠胀感.入院查体示:右臀部可触及7 cm×5 cm肿物,质软,边界欠清,活动度可,无压痛,皮温、皮色无异常.腹压升高时肿物明显突出,腹压降低时肿物部分还纳.     

三氧化二砷注射液治疗晚期胆囊癌

我们试用三氧化二砷注射液治疗晚期胆囊癌获得完全缓解1例,疗效显著,类似治疗国内外均未见报道.现报告如下:1 临床资料患者郭××,男性,70岁.因皮肤、巩膜黄染2月,行胆囊癌姑息术后1月,于1997年9月23日收住入科.患者1997年7月下旬起出现皮肤、巩膜黄染伴乏力,进行性加重,CT检查发现胆囊占位,拟诊胆囊癌,于8月19日行手术治疗.术中见胆囊底部纸3cm×2cm肿块,侵及胆囊床周围肝组织,十二指肠韧带及门静脉周围有多枚肿大淋巴结,相互粘连,无法切除,仅行姑息性胆囊切除和胆肠吻合术.术后病理:胆囊管状乳头状腺癌,浸润囊壁全层     

乳腺癌首发头皮转移1例

患者女,30岁,1993年5月偶然发现头顶偏右后侧有一包块,在当地县医院行包块切除术,术后病理为汗腺癌。一年后出现颈部淋巴结肿大,又在该院行颈淋巴结清扫术,病理报告为汗腺癌淋巴结转移。此后半年又发现右腋窝及右锁骨上淋巴结肿大,再在该院行局部淋巴结扩清术,病理送上级医院检查报告为淋巴结内转移性腺癌,给予化疗及~(60)C_0后装     

右肺癌切除术后合并右侧胸腔侵袭性曲霉感染1例

1病案摘要患者女性,65岁。因右肺腺癌术后2年余,咳嗽、咳痰、发热20天余入院。患者因体检发现右肺占位,于2009年5月21日在江苏省肿瘤医院行"右中下肺切除术+淋巴结清扫术",术后病理显示"右肺低分化腺癌",多组淋巴结均未见转移,术后未行辅助化疗。2009年11月,患者于江苏省中医院复查胸部CT显示"纵隔及右锁骨上淋巴结肿大",考虑     

一例结肠造口狭窄的护理

患者 ,女 ,6 6岁。 1999年 1月 8日因下腹疼痛 ,大便带血 ,在当地医院行直肠腺癌Ｄｉｘｏｎ手术 ,术后病理示 :直肠乙状结肠腺癌。术后恢复良好。同年 11月发现肿瘤复发 ,再次行直肠Ｍｉｌｅｓ术。 3个月后患者逐渐出现排便困难 ,造口明显缩窄、变小 ,行造口狭窄扩创 ,症状缓解。术后 5个月造口再次出现排便、排气困难 ,排便时需用棉棒通畅后方能排出 ,造口处有撕裂样疼痛。为治疗造口狭窄于 2 0 0 0年 5月 16日收入我院。经充分术前准备后于 5月 2 2日手术切除原造瘘口 ,予以腹壁修补 ,于左侧腹壁平脐处重新造口。术后通过严密的病情观察与…     

双侧原发性乳腺癌二例报告

双侧原发性乳腺癌少见,国内报道发病率为0.4％～2％,较国外为低。我院1978年～1991年手术治疗乳腺癌158例,经病理证实的双侧原发性乳腺癌仅2例,本组发病率为1.2％,现报告如下。例1.女性,57岁。首次因左乳腺外上象限肿块1个月,直径1.5cm。于1981年9月1日行区段切除,术中病理证实为乳腺癌,立即施左全乳单纯切除术。术后病理诊断:左乳腺单纯癌。第二次因右乳腺外上方肿块2个月,直径2.5cm。于1988年5月13日行区段切除,术中病理证实为乳腺癌,立即施右乳腺癌根治术。术后清理:右乳腺浸润性导管癌。例2.女性,26岁,因双侧乳腺外上象限肿块2个月,直径各为2cm。于1991年6月24日行区段     

腮腺转移性混合瘤一例

患者女 ,2 7岁。发现右腮腺肿块 5个月 ,于 1991年 5月入院。行右腮腺浅叶切除 ,术后病理示右腮腺良性混合瘤。术后 17个月 (1992年 10月 )在原右腮腺手术区出现复发肿块再次入院。X线肺片提示两肺外侧带结节状影 ,疑转移灶。右腮腺复发灶切除后 ,病理仍示良性混合瘤 ;左肺转移灶切除后 ,病理诊断为 :左肺转移性混合瘤 (病灶位于肺泡周围 ,排除细支气管以上支气管腺体来源混合瘤 )。患者在首次术后 2年 (1993年 5月 )、4年 (1995年 6月 )又因右肺转移灶和左胸膜转移灶在我院分别行转移灶切除 ,术后病理均示转移性混合瘤。首次术后 6年半 (1…     

A case of malignant eccrine spiradenoma metastatic to intramammary lymph node

Eccrine spiradenoma (ES) is a fairly common, benign, cutaneous tumor originating from the sweat glands. In contrast, the malignant counterpart of ES, malignant eccrine spiradenoma (MES), is extremely rare. A long-standing lesion rarely begins to enlarge rapidly. A growth that results in ulceration or discoloration may be associated with malignant transformation. We present the first reported case of this tumor metastasizing to an intramammary lymph node (IMLN). The uncommon metastasizing focus of the periumbilical MES and its histopathological similarity with a primary breast carcinoma made the diagnosis difficult.     

A case of malignant eccrine spiradenoma metastatic to intramammary lymph node.

Eccrine spiradenoma (ES) is a fairly common, benign, cutaneous tumor originating from the sweat glands. In contrast, the malignant counterpart of ES, malignant eccrine spiradenoma (MES), is extremely rare. A long-standing lesion rarely begins to enlarge rapidly. A growth that results in ulceration or discoloration may be associated with malignant transformation. We present the first reported case of this tumor metastasizing to an intramammary lymph node (IMLN). The uncommon metastasizing focus of the periumbilical MES and its histopathological similarity with a primary breast carcinoma made the diagnosis difficult.     

Malignant eccrine spiradenoma of the hand

A malignant eccrine spiradenoma (MES) of the hand is described in a patient who developed bilateral pulmonary metastasis more than 10 years later. A review of the literature including observations on clinical behavior and recommendations for treatment of this rare adnexal tumor is presented.     

小汗腺螺旋腺瘤1例报告

报告1例小汗腺螺旋腺瘤。患者,女,60岁。因发现右上臂肿块一年余就诊。皮肤科检查：肿块位于皮下,直径0.5cm,质地中等,活动度可。组织病理检查：肿瘤呈分叶状,与周围组织界限清楚。瘤细胞内毛细血管丰富,瘤细胞围绕毛细血管排列呈片状、实性条索状、花瓣样及腺管样,部分区域似玫瑰花样排列。肿瘤主要由两种瘤细胞组成：一种瘤细胞体积稍大,呈卵圆形及立方形,细胞核呈类圆形,淡染;另一种瘤细胞形态似基底细胞样,体积较小,卵圆形,细胞核深染。免疫组化：肿瘤细胞SMA（＋）,CK5/6（＋）,CK（＋）,EMA（＋）。结合临床和组织病理表现,诊断为小汗腺螺旋腺瘤。     

胰腺恶性孤立性纤维性肿瘤1例并文献复习

目的:讨论孤立性纤维性肿瘤（solitary fibrous tumor,SFT）的临床特征、病理学表现、影像学表现、诊断方法、鉴别诊断、治疗及预后,以提高临床医生对此病的认识及诊治水平。方法:报道1例术后肿瘤2次复发的胰腺恶性SFT的临床病理资料并文献复习。结果:患者女性,59岁,以“体检发现胰尾部肿物10天”为主诉首次入院,入院后诊断为胰体部占位,行胰体尾切除、脾切除术,术后石蜡病理提示胰体尾交界性梭形细胞肿瘤,考虑孤立性纤维性肿瘤。术后5月余复查,肿瘤复发于左上腹网膜囊内,再次手术切除复发肿物,术后石蜡病理提示交界性或低度恶性孤立性纤维性肿瘤。距二次术后4月余复查,肿瘤再次复发于左上腹网膜囊内,再次予手术切除肿物,术后石蜡病理提示交界性或低度恶性孤立性纤维性肿瘤。结论:胰腺恶性SFT病例极其罕见,术后复发者更是少之又少,确诊主要依靠病理组织形态学及免疫组化标记,并与其他相关性疾病加以鉴别,治疗方法以手术完全切除肿物为主,注意定期复查及远期随访。     

膀胱脐尿管癌合并膀胱尿路上皮癌1例及文献复习

目的:探讨脐尿管癌的诊断和治疗方法。方法:报道1例膀胱脐尿管癌合并膀胱尿路上皮癌,探讨脐尿管癌的诊治。结果:患者为72岁老年男性,2004年手术确诊为膀胱尿路上皮癌。2013年6月因右下腹肿块手术,术后病理提示肿块为膀胱脐尿管腺癌。故患者诊断为膀胱癌及膀胱脐尿管双原发癌。结论:脐尿管癌是来源于脐尿管残存组织的少见恶性上皮肿瘤,由于发生部位特殊,早期诊断困难。膀胱部分切除术是主要的治疗方法,病理分期是主要的预后因素。目前仍没有公认的化疗方法,预后较差。     

阴茎原发性恶性黑色素瘤1例报告并文献复习

目的:探讨阴茎原发恶性黑色素瘤的生物学行为、临床病理特征、诊断、治疗方法及其预后。方法:报告1例阴茎原发性恶性黑色素瘤的诊断治疗及随访情况,并结合国内外文献进行分析。结果:本例患者肿瘤分期为Ⅰ期,行阴茎部分切除术及双侧腹股沟淋巴结清扫术,同时给予化疗及生物治疗。术后随访24 个月,体格检查正常,行盆腔 MRI 检查未见复发及远处转移。结论:阴茎原发恶性黑色素瘤临床罕见,恶性程度高,总体预后差,其确诊依靠病理,外科手术为主要治疗手段,术后结合化疗以及生物治疗可延长生存期。     

Malignant Adenomyoepithelioma of the Breast and Responsiveness to Eribulin

Adenomyoepithelioma (AME) of the breast is an uncommon tumor characterized by its dual differentiation into luminal cells and myoepithelial cells. In most cases these tumors have a benign clinical course, but distant metastases have been reported. We present the case of a 51-year-old woman diagnosed with malignant AME. The patient underwent a right modified radical mastectomy, and pathological examination confirmed the diagnosis of malignant AME. Ten months after the operation, multiple hepatic, pleural, and abdominal wall metastases were detected. A number of palliative chemotherapeutic agents were tried, including anthracycline and taxanes. However, the disease continued to progress, and superior vena cava syndrome developed as a result of direct tumor invasion. The patient received salvage eribulin monotherapy. After two cycles of this treatment, her clinical symptoms were ameliorated, and a computed tomography scan showed a partial response. Eribulin chemotherapy was thus effective in treating malignant AME in this case.     

Cystic liver metastases from lung adenocarcinoma: a case report

Cystic hepatic metastases arising from lung cancer are rare. We herein describe a case of a 71-year-old women admitted to our hospital for abdominal pain 6 months after the resection of a lung adenocarcinoma. Two cystic lesions of the liver were discovered at abdominal ultrasonography and computerized tomography scan. An ERCP excluded a biliary adenoma or adenocarcinoma, and an ultrasound-guided liver biopsy was negative for malignant cells. For persistence of symptoms and lack of a diagnosis, the patient underwent an exploratory laparotomy, a surgical biopsy with a diagnosis of adenocarcinoma, and a consequent right hepatectomy. After 2 years of follow-up, the patient is well and disease free. Although cystic liver metastasis are rare and a differential diagnosis difficult, the malignant nature should always be considered in the differential diagnosis of hepatic cysts to offer the patient the best treatment.     

A Primary Sacral Melanoma of Unknown Origin: A Case Report

Malignant melanoma caused by malignant transformation of melanocytes is associated with high mortality and is difficult to manage. Metastasis is not uncommon (up to 31% of all cases) and is closely associated with a poor prognosis. Although rare (4–5%), extracutaneous melanoma has been reported; however, primary malignant melanoma of the sacrum is extremely rare (only three case reports to date). Here, we present a 51-year-old patient who underwent surgical treatment for a lesion of the spinal canal and associated bony structures; extensive aggressive resection was required. She underwent partial sacrectomy and lumbo-iliac fixation (to maintain spinal stability). Pathology revealed malignant melanoma. We discuss the diagnosis, surgical intervention, and postoperative follow-up, which may assist clinicians. Although metastatic malignant melanoma is usually fatal, primary extracutaneous melanoma of the spine may respond well to surgery and adjuvant radiotherapy.