Lipoma of the stomach

Summary Gastric lipomas are among the rare benign tumors of the stomach. Only 54 cases appear in the English literature. We have reported a case of such a tumor and have discussed pertinent clinical, pathologic, and radiologic features.     

Leiomyoblastoma of the stomach

The leiomyoblastoma of the gastrointestinal tract is a tumour which arises from the smooth musculature. With regard to its malignancy it is between leiomyoma on the one hand and leiomyosarcoma on the other. In 12% of the patients the leiomyoblastoma shows a malignant course. Males somewhat more frequently fall ill with leiomyoblastoma than females (ratio 1.3:1). The average age of the patients is 56.6 years. The most impressive clinical symptom is the gastrointestinal haemorrhage. In an own case problems of therapy are discussed. The mere enucleation of the tumour is not enough for cure. The resection of the stomach, at least of the involved part of the stomach, seems to be necessary.     

Hemodynamics of the stomach

Summary A method is described for measuring the change in blood pressure gradient across the stomach of the dog in response to changes in blood flow.In 16 dogs pressure-gradient responses were measured and vascular resistance calculated. The rise in pressure gradient was not proportionate to the increase in blood flow. Resistance, therefore, decreased as blood flow rose. The decline in resistance to increments in flow was especially marked till flow reached a rate of 60 ml./min. Beyond this flow the fall in resistance became slight. It appears that autoregulation does not occur to any appreciable degree in the gastric vascular bed.When flow was lowered over the same range used in raising flow, pressure values somewhat different were obtained, suggesting a hysteresis effect.Submitted to the Midwestern Section Meeting of the American Federation for Clinical Research, Chicago, Ill., Nov. 2, 1961.The authors are indebted to Dr. Francis J. Haddy for continued advice and criticism in the course of these investigations, and to Lyle Brown, James McGuire, Albert Malanche, and Miguel Ramirez for technical assistance.     

Leiomyosarcoma of the stomach

Summary The literature is reviewed, and 10 cases of leiomyosarcoma of the stomach are presented. Nine of these were encountered during the 10-year period of 1948–58. The clinical features and roentgenologic diagnosis are discussed. Two cases were of microscopically benign leiomyomas that eventually metastasized. One case involved a gastric adenocarcinoma. A case with gastric fistula leading to the center of a large, necrotic, exogastric leiomyosarcoma is presented. There were 3 long-term survivals, 1 of five years and 2 of ten years. Emphasis is placed on the slow rate of metastasis and the excellent prognosis of long-term survival when the tumors are thoroughly removed.It is suggested that leiomyosarcoma be considered in those cases where (a) gastric tumor, or (b) gastric fistula, or (c) barium outside the confines of the stomach is radiogrphaically shown in the examination of the gastrointestinal tract, in patients whose clinical picture is one of (a) anemia secondary to blood loss, (b) vague epigastric complaints, and (c) long duration of symptoms.     

Sarcoidosis of the stomach

The article describes sarcoidosis affected mucous membrane of the stomach. On the basis of literature data and personal observations (2 cases of sarcoidosis affected the mucous membrane of the stomach in 40 sarcoidosis patients examined), the endoscopic characteristics of the mucous membrane of the stomach are given. It is found that the process is frequently localized in the antral portion of the stomach being combined with +pyloric stenosis. Patients with chronic sarcoidosis were examined, unlike foreign authors who surveyed those with first sarcoidosis. The presence of "sarcoid" changes in the mucous membrane of the stomach appears to be one of the signs of the process manifestation and requires hormonal agents to be used. It is necessary to conduct endoscopic examinations of the gastrointestinal tract to detect both the disease and different chronic lesions of the stomach in a specialized hospital where sarcoidosis patients are treated.     

Adenomyoma of the stomach

Two cases of adenomyoma of the stomach and a review of previous reports in the literature are presented. Adenomyoma is a benign lesion of the pylorus of the stomach composed of smooth muscle, cysts, and glandular structures lined by tall columnar epithelium, Brunner's glands, and sometimes pancreatic tissue. The histopathological and radiological characteristics of this lesion are discussed.