Anomaly and tumor of kidney and urinary tract

2007475 MRI manifestations of renal oncocytoma.JI Jiansong(纪建松) , et al. Dept Radiol, Sir Run RunShaw Hosp, Zhejiang Univ, Hangzhou 310016. Chin JRadiol 2007;41(10):1087 -1089. Objective To analyze the MRI findings of renal on-cocytoma, and to improve the ability for the diagnosis.Methods We retrospectively reviewed MRI findings ofsults Sixcases had a solitary lesion, and 1 of themac-companied with renal clear-cell carcinoma. Tumors ap-peared as round with diameter 1.5 to 3.8 cm,…     

Relationships between serum adiponectin and soluble TNF-α receptors and glucose and lipid oxidation in lean and obese subjects

Insulin resistance might be associated with an impaired ability of insulin to stimulate glucose oxidation and inhibit lipid oxidation. Insulin action is also inversely associated with TNF-α system and positively related to adiponectin. The aim of the present study was to analyze the associations between serum adiponectin, soluble TNF-α receptors concentrations and the whole-body insulin sensitivity, lipid and glucose oxidation, non-oxidative glucose metabolism (NOGM) and metabolic flexibility in lean and obese subjects. We examined 53 subjects: 25 lean (BMI < 25 kg × m⁻²) and 28 with overweight or obesity (BMI > 25 kg × m⁻²) with normal glucose tolerance. Hyperinsulinemic euglycemic clamp and indirect calorimetry were performed. An increase in respiratory exchange ratio in response to insulin was used as a measure of metabolic flexibility. Obese subjects had lower insulin sensitivity, adiponectin and higher sTNFR1 (all P < 0.001) and sTNFR2 (P = 0.001). Insulin sensitivity was positively related to adiponectin (r = 0.49, P < 0.001) and negatively related to sTNFR1 (r = −0.40, P = 0.004) and sTNFR2 (r = −0.52, P < 0.001). Adiponectin was related to the rate of glucose (r = 0.47, P < 0.001) and lipid (r = −0.40, P = 0.003) oxidation during the clamp, NOGM (r = 0.41, P = 0.002) and metabolic flexibility (r = 0.36, P = 0.007). Serum sTNFR1 and sTNFR2 were associated with the rate of glucose (r = −0.45, P = 0.001; r = −0.51, P < 0.001, respectively) and lipid (r = 0.52, P < 0.001; r = 0.46, P = 0.001, respectively) oxidation during hyperinsulinemia, NOGM (r = −0.31, P = 0.02; r = −0.43, P = 0.002, respectively) and metabolic flexibility (r = −0.47 and r = −0.51, respectively, both P < 0.001) in an opposite manner than adiponectin. Our data suggest that soluble TNF-α receptors and adiponectin have multiple effects on glucose and lipid metabolism in obesity.     

Periodontitis and diabetes mellitus—an awareness and perception study among endocrinologists and diabetologists

International Journal of Diabetes in Developing Countries - Periodontitis is a chronic inflammatory disease caused by pathogenic dental plaque which causes microbial dysbiosis leading to...     

Lipids,Lipoproteins, and Metabolites and Risk of Myocardial Infarction and Stroke

Background

Blood lipids are established risk factors for myocardial infarction (MI), but uncertainty persists about the relevance of lipids, lipoprotein particles, and circulating metabolites for MI and stroke subtypes.

Thromboelastography and recombinant factor VIIa—hemophilia and beyond

Thromboelastography (TEG), which records the continuous profiles of whole blood (WB) coagulation, can be used to evaluate the effects of hemostatic agents, such as recombinant factor VII (rFVIIa). Our group has developed a revised TEG model, involving activation with minute amounts of tissue factor and subsequent signal processing, and has used this method to evaluate the effects of rFVIIa both in patients with hemophilia and in those receiving vitamin K antagonist (VKA) thromboprophylaxis. We review the early results of our investigations, which suggest that, in clinical situations where rFVIIa has shown benefit, the changes in the profiles obtained by TEG recording appear to correlate with the clinical outcome.     

Alcohol and Atherosclerosis

Objectives To study the relationship between alcohol and atherosclerosis （AS）. Methods The paper reviewed the mechanism of the alcohol leading to AS from four aspects such as the introduction of alcohol and AS, imbalance of oxidationantioxidation system, oxygen free radical （OFR） and endothelium cell （EC） apoptosis, apoptosis and AS. Results Excessive alcohol could lead to imbalance of oxidation-antioxidation system, and increase OFR, in the meanwhile, OFR could lead to EC apoptosis, which could lead to AS.     

Meetings and Courses

Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the HBPD INT.Section editorShui-Ying LeiEmail: hbpdje@mail.hz.zj.cn     

Meetings and Courses

<正>Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the Hepatobiliary & Pancreatic Diseases International.     

Crohn’s and colitis in children and adolescents

Crohn’s disease and ulcerative colitis can be grouped as the inflammatory bowel diseases (IBD). These conditions have become increasingly common in recent years, including in children and young people. Although much is known about aspects of the pathogenesis of these diseases, the precise aetiology is not yet understood, and there remains no cure. Recent data has illustrated the importance of a number of genes-several of these are important in the onset of IBD in early life, including in infancy. Pain, diarrhoea and weight loss are typical symptoms of paediatric Crohn’s disease whereas bloody diarrhoea is more typical of colitis in children. However, atypical symptoms may occur in both conditions: these include isolated impairment of linear growth or presentation with extra-intestinal manifestations such as erythema nodosum. Growth and nutrition are commonly compromised at diagnosis in both Crohn’s disease and colitis. Consideration of possible IBD and completion of appropriate investigations are essential to ensure prompt diagnosis, thereby avoiding the consequences of diagnostic delay. Patterns of disease including location and progression of IBD in childhood differ substantially from adult-onset disease. Various treatment options are available for children and adolescents with IBD. Exclusive enteral nutrition plays a central role in the induction of remission of active Crohn’s disease. Medical and surgical therapies need to considered within the context of a growing and developing child. The overall management of these chronic conditions in children should include multi-disciplinary expertise, with focus upon maintaining control of gut inflammation, optimising nutrition, growth and quality of life, whilst preventing disease or treatment-related complications.     

Meetings and Courses

Announcements for this section should be submitted in the correct format at least 3 months before the required     

Meetings and Courses

Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the HBPD INT.Section editor Shui-Ying Lei Email: hbpdje@mail.hz.zj.cnFebruary, 2007 2007 pancreas cancer February 21-23, 2007; Rome, Italy Pancreas Cancer 2007 will be a meeting point where different diagnostic and therapeutic modalities are examined, focusing on recent ad…     

Meetings and Courses

<正>Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication. This list is provided as a service to readers; inclusion does not imply endorsement by the Hepatobiliary & Pancreatic Diseases International.     

Rest and Relax

Life is made up of exercise and activity;but,if life is to continue for any extended time,there must also be rest and relaxation.A bal-ance between activity and rest is the objectiveof all intelligent living-not too much activity,yet not too much rest.Life for most people is a very unbalancedaffair.Jobs in modern industry are so special-ized that usually one part or one set of organsof the body is overstrained while others arealways in need of exereise.Much of the fatigue and strain from thework we do today is the result of unnecessarytension.Every job we do requires that certain     

Endocrinology and Metabolism

2020036 Comparative analysis of clinical features of fulminant type 1 diabetes.WANG Yajing(王雅静),et al.Dept Endocrinol,1st Med Center,Chin PLA General Hosp,Beijing 100853.Med J Chin PLA 2019;44(11):937-94.Objective To analyze and compare the clinical features of fulminant type 1 diabetes mellitus(FT1D M).     

Jejunum and ileum

2005219 NOD2/CARD15 gene polymorphisms and susceptibility to Crohn's disease in Chinese Han population. GAO Min(高敏), et al. Dept Digestol, Sir Run Shaw Hosp, Sch Med, Zhejiang Univ, Hangzhou 310016. Chin J Intern Med, 2005;44(3): 210-212. Objective: Previous studies have shown NOD2/ CABD15 gene is the first susceptibility gene to     

Meetings and Courses

Announcements for this section should be submitted in the correct format at least 3 months before the required date of publication.This list is provided as a service to readers;inclusion does not imply endorsement by the Hepatobiliary&Pancreatic Diseases International.     

Allergy and Immunity

4.1.Autoimmune disease2005303 Peripheral blood mRNA and interferongene expression in systemic lupus erythematosus.TANG Jianping(汤建平),et al.Dept Rheumatol,RenjiHosp,Shanghai 2nd Med Univ Shanghai 200001.Chin JIntern Med 2005;44(2):106-110.